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Importance of PET/CT Scan Use in Planning Radiation Therapy for Lymphoma
Milana, Mitric-Askovic,Marko, Erak,Miroslav, Latinovic,Tihomir, Dugandzija Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.5
Background: Radiation therapy is a key part of the combined modality treatment for Hodgkin's lymphoma (HL) and non-Hodgkin's lymphoma (NHL), which can achieve locoregional control of disease. The 3D-conformal radiation oncology can be extended-field (EFRT), involved-field (IFRT) and involved node (INRT). New techniques have resulted in a smaller radiation field and lower dose for critical organs such as lung heart and breast. Materials and Methods: In our research, we made a virtual simulation for one patient who was treated in four different radiotherapeutic techniques: mantle field (MFRT), EFRT, IFRT and INRT. After delineatiion we compared dose-volume histograms for each technique. The fusion of CT for planning radiotherapy with the initial PET/CT was made using Softver Xio 4.6 in the Focal program. The dose for all four techniques was 36Gy. Results: Our results support the use of PET/CT in radiation therapy planning. With IFRT and INRT, the burden on the organs at risk is less than with MFRT and EFRT. On the other hand, the dose distribution in the target volume is much better with the latter. Conclusions: The aim of modern radiotherapy of HL and NHL is to reduce the intensity of treatment and therefore PET/CT should be used to reduce and not increase the amount of tissue receiving radiation.
Ivana Lj. Validži,Nadica D. Abazovi,Miodrag Mitric 대한금속·재료학회 2012 METALS AND MATERIALS International Vol.18 No.6
We report the organic synthesis and growth of antimony sulfide (Sb2S3) amorphous nanospheres to nanowires via a simple, colloidal synthetic method. Amorphous Sb2S3 nanospheres self-assembly in wires formation was dispersed in isopropyl alcohol. With increased heating time, Sb2S3 nanospheres grew into Sb2S3nanowires, probably involving both mechanisms of Ostwald-ripening and spherical nanoparticle self-organization through oriented-attachment of individual nanoparticles. Also, the as-synthesized Sb2S3 nanowires with different heating times (0, 5 and 10 min.) from the moment of appearance of the Sb2S3 precipitate were analyzed. The observed nanowires become longer with increased heating time and are around 100nm in diameter and 10-20 μm in length. UV-Vis absorption spectroscopy reveals that the optical band-gap energy of the Sb2S3 nanowires is independent of the heating times and is found to be ~1.5-1.6 eV. The optical band-gap energy found for amorphous Sb2S3 nanospheres was also ~1.5 eV. The structure of Sb2S3samples was refined down to R-factors of 10.82, 11.76 and 12.08%. The refinement showed that Sb2S3powder belongs to the orthorhombic type with space group Pbnm (no. 62) and that Sb2S3 nanowires grow along the [010] direction.
Rade Surudzic,Ana Jankovic,Miodrag Mitric,Ivana Matic,Zorica D. Juranic,Ljiljana Zivkovic,Vesna Miskovic-Stankovic,이경엽,박수진,David Hui 한국공업화학회 2016 Journal of Industrial and Engineering Chemistry Vol.34 No.-
Poly(vinyl alcohol)/graphene (PVA/Gr) nanocomposite was synthesized with the aim of developing anovel improved material. The PVA/Gr nanocomposite was characterized by UV–visible spectroscopy,cyclic voltammetry, Raman spectroscopy, X-ray diffraction, Fourier transform infrared spectroscopy, andX-ray photoelectron spectroscopy analyses, and the interaction of PVA molecules with graphene wasexamined. Introduction of Gr led to improved mechanical and thermal properties of the PVA/Grnanocomposite compared to pure PVA, as well as strong antibacterial activity against the bacterial strainStaphylococcus aureus. The PVA/Gr nanocomposite was non-cytotoxic against healthy peripheral bloodmononuclear cells by MTT assay, indicating its high potential for biomedical applications.