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Mingyun Lee,Jong-Nam Oh,Gyung Cheol Choe,Kwang-Hwan Choi,Dong-Kyung Lee,Seung-Hun Kim,Jinsol Jeong,Yelim Ahn,Chang-Kyu Lee Asian Australasian Association of Animal Productio 2023 Animal Bioscience Vol.36 No.12
Objective: Nanog homeobox (NANOG) is a core transcription factor that contributes to pluripotency along with octamer binding transcription factor-4 (OCT4) and sex determining region-Y box-2 (SOX2). It is an epiblast lineage marker in mammalian pre-implantation embryos and exhibits a species-specific expression pattern. Therefore, it is important to understand the lineage of NANOG, the trophectoderm, and the primitive endoderm in the pig embryo. Methods: A loss- and gain-of-function analysis was done to determine the role of NANOG in lineage specification in parthenogenetic porcine blastocysts. We analyzed the relationship between NANOG and pluripotent core transcription factors and other lineage makers. Results: In NANOG-null late blastocysts, OCT4-, SOX2-, and SOX17-positive cells were decreased, whereas GATA binding protein 6 (GATA6)-positive cells were increased. Quantitative real-time polymerase chain reaction revealed that the expression of SOX2 was decreased in NANOG-null blastocysts, whereas that of primitive endoderm makers, except SOX17, was increased. In NANOG-overexpressing blastocysts, caudal type homeobox 2 (CDX2-), SOX17-, and GATA6-positive cells were decreased. The results indicated that the expression of primitive endoderm markers and trophectoderm-related genes was decreased. Conclusion: Taken together, the results demonstrate that NANOG is involved in the epiblast and primitive endoderm differentiation and is essential for maintaining pluripotency within the epiblast.
( Mingyun Ko ),( Changho Song ) 물리치료재활과학회 2018 Physical therapy rehabilitation science Vol.7 No.2
Objective: This study aimed to compare the effects of core exercise methods on muscle activation and muscle thickness in healthy young adults and to propose effective core exercise methods. Design: Three-group pretest-posttest design. Methods: A total of 30 healthy young adults (14 males, 16 females) voluntarily participated in the study. Subjects were randomized to the prone plank exercise (n=10), reverse plank exercise (n=10), or bridge exercise (n=10) groups. Muscle activity and thickness of the rectus abdominis (RA), multifidus (MF), external oblique (EO), and internal oblique (IO) muscles were measured using surface electromyography and ultrasound. Subjects from each group participated in the exercises five times a week, with five 20-second sets during week 1. The set time was increased by 10 seconds per week. Results: Muscle activity and thickness in the prone plank, reverse plank, and bridge exercise group were statistically significant different for RA, MF, EO, and IO changes over time, and interaction between time and groups were also significantly different (p<0.05). We analyzed statistically significant differences between groups using a one-way analysis of variance for each period. A significant difference was observed after 4 weeks of exercise (p<0.05). Conclusions: The results suggest that the prone plank exercise is a beneficial method for enhancing muscle activation and thickness of the RA, EO, and IO compared to the reverse plank and bridge exercises. On the other hand, the reverse plank and bridge exercises are effective methods for enhancing the MF compared to the prone plank exercise.
A Study on Shooting Device of 3D Stereoscopic images using smart phone
Mingyun Kang,Seoksoo Kim,E-Jung Choi 중소기업융합학회 2015 중소기업융합학회 국제학술대회논문집 Vol.2 No.1
As the stereoscopic image provides the depth-of-focus to feel a real sense of distance, it has been actively studied in various fields including simulation, stereoscopic animation, interactive computers, etc. In this study, the platform which allows learning the stereoscopic image by utilizing a smartphone that is currently being used by public when taking the stereoscopic image and taking a simple stereoscopic image was proposed. The platform presented in this study will help in learning the stereoscopic image and taking a simple stereoscopic image to increase the understanding on the stereoscopic image and its utilization.
Ko, Mingyun,Song, Changho korean Academy of Physical Therapy Rehabilitation 2018 Physical therapy rehabilitation science Vol.7 No.2
Objective: This study aimed to compare the effects of core exercise methods on muscle activation and muscle thickness in healthy young adults and to propose effective core exercise methods. Design: Three-group pretest-posttest design. Methods: A total of 30 healthy young adults (14 males, 16 females) voluntarily participated in the study. Subjects were randomized to the prone plank exercise (n=10), reverse plank exercise (n=10), or bridge exercise (n=10) groups. Muscle activity and thickness of the rectus abdominis (RA), multifidus (MF), external oblique (EO), and internal oblique (IO) muscles were measured using surface electromyography and ultrasound. Subjects from each group participated in the exercises five times a week, with five 20-second sets during week 1. The set time was increased by 10 seconds per week. Results: Muscle activity and thickness in the prone plank, reverse plank, and bridge exercise group were statistically significant different for RA, MF, EO, and IO changes over time, and interaction between time and groups were also significantly different (p<0.05). We analyzed statistically significant differences between groups using a one-way analysis of variance for each period. A significant difference was observed after 4 weeks of exercise (p<0.05). Conclusions: The results suggest that the prone plank exercise is a beneficial method for enhancing muscle activation and thickness of the RA, EO, and IO compared to the reverse plank and bridge exercises. On the other hand, the reverse plank and bridge exercises are effective methods for enhancing the MF compared to the prone plank exercise.
미래차 시트의 구조변화와 피로저감 시트용 6절 링크 Leg rest 부하 예측에 관한 연구
신민균(Mingyun Shin),차재권(Jaekown Cha),정요한(Yohan Jung),정호진(Hojin Jung),육형섭(Hyungsub Yook) 한국자동차공학회 2022 한국자동차공학회 학술대회 및 전시회 Vol.2022 No.11
Recently, the development and marketing of fatigue-reducing seats has been active, and this product is expected to provide better rest and comfort to passengers during autonomous driving and charging of electric vehicles. The core technology of the fatigue reduction seat is the proper positioning of the upper and lower body of the human body and the development of a mechanical device to implement it. Leg rests that support below the knees were generally applied only to the rear seats, but with the expansion of the fatigue-reducing seats, they are also being applied to the driver and front passenger seats. Domestic companies have secured leg rest mechanical design capabilities, but lack the ability to determine the motor capacity that operates them. In this study, structural changes in future car seats, development trends of fatigue-reducing seats and leg rests, and evaluation methods were investigated, and finally, a model was developed to predict the load amount of the 6-section link leg rest motor.
신민균(Mingyun Shin),박상현(Sanghyun Park),권혁모(Hyoukmo Kwon),차재권(Jaekown Cha),강병주(Byungju Kang),김회천(Hoecheon Kim) 한국자동차공학회 2019 한국자동차공학회 학술대회 및 전시회 Vol.2019 No.11
Many companies that have technological catch-up strategies have standardized and quantified the information and know-how accumulated at the imitation phase. However, excessive regulation has a negative impact on qualitative growth. Initial operation sound is the start noise of the car’s power seat, and developers are highly skeptical about the regulation. This study investigated the management status, influence factors, measurement levels, improvement methods, and degree of awareness. In conclusion, soft starters and limit switches are the most effective way to improve initial operation sound. The survey showed that only 37% perceived the difference when 30 people heard product with 10㏈ difference in the initial operation sound.
몰입형 무대 연출을 위한 시나리오 및 콘텐츠 설계 시스템
문명운 ( Mingyun Wen ),치옥용 ( Yulong Xi ),국윤창 ( Yoonchang Kook ),홍성욱 ( Tony Hong ),김준오 ( Junoh Kim ),조경은 ( Kyungeun Cho ) 한국정보처리학회 2017 한국정보처리학회 학술대회논문집 Vol.24 No.1
Today multimedia technologies are playing an increasingly important role in games, movies, and live performances. In this paper, we design a flexible interactive system integrated with gesture recognition, skeleton tracking, internet communication, and content edition using multi-sensors to direct and control the performance on stage. In this system, the performer can control the elements showed on stage through corresponding gestures and body movements during the performance. The system provides an easier way for users to change the content of the performance if they intent to do.