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Effect of Impeller Blade Number on Kla in Mechanically Agitated Vessels
Lu Wei Ming,Wu Hong Zhang,Chou Cheng Ying 한국화학공학회 1999 Korean Journal of Chemical Engineering Vol.16 No.5
Effects of impeller blade number on gas dispersion and mass transfer rate were thoroughly investigated for mechanically agitated vessels equipped with 2-, 4-, 6- and 8-straight blades disk turbine impellers. The results show that under the same rotational speed, the impeller with more blades always can disperse gas more effectively, which induces a higher value of $lt;K_La$gt;. However, with the same total power consumption, the 4-blade impeller can obtain a higher $lt;K_La$gt; value than the 6- and 8-blade impellers under a lower gassing rate condition (Q-g$lt;0.5vvm), but if Q_g) exceeds 0.5vvm, the 6-blade impeller will perform better than the 4- and 8- blade impellers. To examine the results obtained from the single impeller systems, the same approach is applied to measure $lt;K_La$gt; values for the triple stage 6-blade impeller system (3×6) and quadruple stage 4-blade impeller system (4×4). From the experimental results, it can be found that the 4×4 system gives higher $lt;K_La$gt; value than the 3×6 system under gas completely dispersed conditions. By correlating $lt;K_La$gt; with n_b, N and V_s, the following correlation can be given as: $lt;K_La$gt; = 0.00119n^(0.62)_bN^(1.56)V^(0.4)_s $lt;K_La$gt; = 0.0297n^(0.1)_b(P_s/V)^(0.34)V^(0.48)_s These two correlations can also be used to evaluate the mass transfer coefficient of each impeller region for the multiple impeller systems and the deviation is always less than 10%.
Lu Yunjun,Li Shu,Shen Xiaodong,Zhao Yan,Zhou Dongming,Hu Dan,Cai Xushen,Lu Lixia,Xiong Xiaohui,Li Ming,Cao Min 한국미생물학회 2021 The journal of microbiology Vol.59 No.10
Streptococcus suis serotype 2 (S. suis 2) is an important zoonotic pathogen that presents a significant threat both to pigs and to workers in the pork industry. The initial steps of S. suis 2 pathogenesis are unclear. In this study, we found that the type II histidine triad protein HtpsC from the highly virulent Chinese isolate 05ZYH33 is structurally similar to internalin A (InlA) from Listeria monocytogenes, which plays an important role in mediating listerial invasion of epithelial cells. To determine if HtpsC and InlA function similarly, an isogenic htpsC mutant (ΔhtpsC) was generated in S. suis by homologous recombination. The htpsC deletion strain exhibited a diminished ability to adhere to and invade epithelial cells from different sources. Double immunofluorescence microscopy also revealed reduced survival of the ΔhtpsC mutant after cocultivation with epithelium. Adhesion to epithelium and invasion by the wild type strain was inhibited by a monoclonal antibody against E-cadherin. In contrast, the htpsC-deficient mutant was unaffected by the same treatment, suggesting that E-cadherin is the host-cell receptor that interacts with HtpsC and facilitates bacterial internalization. Based on these results, we propose that HtpsC is involved in the process by which S. suis 2 penetrates host epithelial cells, and that this protein is an important virulence factor associated with cell adhesion and invasion.
Lu, Zhi-Hao,Yang, Li,Yu, Jing-Wei,Lu, Ming,Li, Jian,Zhou, Jun,Wang, Xi-Cheng,Gong, Ji-Fang,Gao, Jing,Zhang, Xiao-Tian,Li, Jie,Li, Yan,Shen, Lin Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.15
Background: Weight loss during chemotherapy has not been exclusively investigated. Macrophage inhibitory cytokine-1 (MIC-1) might play a role in its etiology. Here, we investigated the prognostic value of weight loss before chemotherapy and its relationship with MIC-1 concentration and its occurrence during chemotherapy in patients with advanced esophageal squamous cell carcinoma (ESCC). Materials and Methods: We analyzed 157 inoperable locally advanced or metastatic ESCC patients receiving first-line chemotherapy. Serum MIC-1 concentrations were assessed before chemotherapy. Patients were assigned into two groups according to their weight loss before or during chemotherapy:>5% weight loss group and ${\leq}5%$ weight loss group. Results: Patients with weight loss>5% before chemotherapy had shorter progression-free survival period (5.8 months vs. 8.7 months; p=0.027) and overall survival (10.8 months vs. 20.0 months; p=0.010). Patients with weight loss >5% during chemotherapy tended to have shorter progression-free survival (6.0 months vs. 8.1 months; p=0.062) and overall survival (8.6 months vs. 18.0 months; p=0.022), and if weight loss was reversed during chemotherapy, survival rates improved. Furthermore, serum MIC-1 concentration was closely related to weight loss before chemotherapy (p=0.001) Conclusions: Weight loss both before and during chemotherapy predicted poor outcome in advanced ESCC patients, and MIC-1 might be involved in the development of weight loss in such patients.
A controller design for high-quality images on microcapsule active-matrix electrophoretic displays
Lu, Chi-Ming,Wey, Chin-Long The Korean Infomation Display Society 2012 Journal of information display Vol.13 No.1
Active-matrix electrophoretic display (AMEPD) is commonly used for the applications of smart handheld reading devices such as e-books and e-news. This paper presents a new reduced waveform lookup table storage method that reduces the associated lookup table by approximately 2n (n is the number of gray levels employed) times the conventional one. The paper also proposes a driving method for image display. The method provides high-speed performance for image display and also effectively eliminates the image residue, achieving high image quality. The prototyped controller was connected to a 6" AMEPD panel, whose excellent display quality demonstrated the effectiveness of the proposed controller design.