French-fried Potato와 Potato Chips製造에 관한 硏究

閔龍圭,呂貞淑 충북대학교 농업과학기술연구소 1986 農業科學硏究 Vol.4 No.-

For the purpose of determining blanchng conditions and qualities of potato products, French-fried potato and potato chips were manufactured from six potato varieties-Irish cobbler, Bintze, Snow Chip, Superior and Norin #1 with various blanching the treatment. The treatments for French-fried potato were done at 85°C for 0, 5, 10, 20 and 30 minutes. Those for potato chips were obtained at 40°C for 0, 3, 5, 7 and 10 minutes. The treatment for 0 min. means without blanching treatment for the both products. The qualityof the products were evaluated by color, texture and panel tests. 1.As blanching period lengthened, Y% increased but chroma% decreased in French-fried potato. This tendency was not so clear in potato chips. 2.Color properties of French-fried potato were observed in the range of 575 to 577nm for dominant wavelength, 29.44 to 40.16% for Y% and 18.83 to 39.84% for chroma. 3.In potato chips, dominant wavelength ranged from 575 to 578nm, Y% 20.91 to 26.91% and chroma 18.83 to 36.82%. 4.The texture properties of French-fried potato-maximum force, total area and curve dstance increased as blanching period lengthened. Maximum force were ranged from 0.19 to 0.63kg, total area 1.44 to 5.77㎠ and curve distance 4.2 to 5.7mm. 5.Brittleness and crispness as criteria of potato chip texture properties were distributed in the range of 2.17 to 5.88kg and 1.79 to 3.57mm respectively.

Coiled-coil structure-dependent interactions between polyQ proteins and Foxo lead to dendrite pathology and behavioral defects

Kwon, Min Jee,Han, Myeong Hoon,Bagley, Joshua A.,Hyeon, Do Young,Ko, Byung Su,Lee, Yun Mi,Cha, In Jun,Kim, Seung Yeol,Kim, Dong Young,Kim, Ho Min,Hwang, Daehee,Lee, Sung Bae,Jan, Yuh Nung National Academy of Sciences 2018 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF Vol.115 No.45

<P><B>Significance</B></P><P>It remains unclear how the structural properties of polyglutamine (polyQ) proteins, which underlie several neurodegenerative disorders, including Huntington’s disease and spinocerebellar ataxias (SCAs), translate into the toxicity of these proteins. Here, we demonstrate that coiled-coil structures in expanded polyQ regions of SCA type 3 (SCA3) proteins cause dendrite defects in <I>Drosophila</I> neurons, as well as behavioral abnormalities. Moreover, interactions of SCA3 with Foxo mediated by coiled-coil domains of these two proteins resulted in functional impairment of this transcription factor, whereas its overexpression significantly rescued the SCA3-induced defects. Our study expanded the current understanding of neuronal pathology mediated by polyQ proteins via the coiled-coil–mediated interactions. These results may have important implications in therapeutic strategies for polyQ protein-related diseases.</P><P>Neurodegenerative disorders, such as Huntington’s diseases and spinocerebellar ataxias (SCAs), are driven by proteins with expanded polyglutamine (polyQ) tracts. Recently, coiled-coil structures in polyQ regions of such proteins were shown to facilitate aggregate formation and ultimately lead to cell death. However, the molecular mechanism linking these structural domains to neuronal toxicity of polyQ proteins remains elusive. Here, we demonstrate that coiled-coil structures in the Q repeat region of SCA type 3 (SCA3) polyQ proteins confer protein toxicity in <I>Drosophila</I> neurons. To functionally characterize coiled-coil structures in the Q repeat regions, we generated three structural variants of SCA3 polyQ proteins: (<I>i</I>) MJDtr-76Q, containing both α-helical coiled-coil and β-sheet hairpin structures in the Q repeat region; (<I>ii</I>) MJDtr-70Q_cc0, possessing only α-helical coiled-coil structures due to the incorporation of β-sheet–breaking residues (Q-to-N or Q-to-E mutations); and (<I>iii</I>) MJDtr-70Q_pQp, with no secondary structure due to the introduced proline residues (Q-to-P mutations). Through comparative analysis of these variants, we found that coiled-coil structures facilitated nuclear localization of SCA3 polyQ proteins and induced dendrite defects in <I>Drosophila</I> dendritic arborization neurons. Furthermore, genetic and functional screening identified the transcription factor Foxo as a target of polyQ proteins, and coiled-coil–mediated interactions of Foxo and polyQ proteins in the nucleus resulted in the observed dendrite and behavioral defects in <I>Drosophila</I>. These results demonstrate that coiled-coil structures of polyQ proteins are crucial for their neuronal toxicity, which is conferred through coiled-coil to coiled-coil interactions with the nuclear targets of these proteins.</P>

규제예산의 논의

여차민(Yuh, Cha Min) 한국규제학회 2013 규제연구 Vol.22 No.2

규제예산(Regulatory Budget)은 모든 규제가 유발하는 비용에 상한을 두어 무분별한 규제의 양산을 통제함으로써 자원의 합리적 배분을 달성하는 것을 목적으로 하며 이론적으로는 강력한 규제개혁 수단으로 평가받는다. 그럼에도 불구하고 우리나라에서는 이론적으로나 실무적으로 규제예산에 대한 논의가 공론화된 바가 없다. 본 연구의 목적은 규제예산이 갖는 매력에도 불구하고 왜 제도화가 무산되었는지에 대한 의문에 기초하여 규제예산의 제도화 가능성을 탐색적으로 분석하는 데 있다.본 연구에서는 편익측정의 배제, 비용추정의 신뢰성, 정책수단의 제약, 적정규모의 결정, 새로운 비용 유발 등 규제예산의 쟁점을 분석틀로 사용하여 제도화 가능성을 분석하였다. 분석결과, 편익배제를 제외한 여타의 쟁점은 역량 및 제도운영의 기술적 문제로 환원하여 해석할 수 있었으며 이는 다소 어려울 수는 있겠으나 제도화 과정에서 해결 불가능한 문제는 아닌 것으로 파악되었다. 결국 규제예산 제도화의 중심에 편익추정 배제의 쟁점이 자리하고 있었으며 이는 규제의 효율성과 형평성 간 선택의 문제로 귀결될 수 있다. 이러한 논의가 시사하는 바는 규제개혁 프로그램의 제도화에 있어서 효율성과 형평성 간 균형의 담보가 핵심적 고려사항이어야 한다는 것이다. Regulatory budget aims at achieving rational allocation of resources by putting a cap at regulatory costs and constraining agencies from issuing ineffective regulations. Thus regulatory budget is theoretically considered as a powerful tool for regulatory reform. Nevertheless, there has been no public debate on Regulatory budget theoretically neither practically in Korea. This study aims at searching the applicability of regulatory budget on the basis of a question of why application of regulatory budget has failed despite its merits.This study examines the applicability of regulatory budget by using five disputed points(exclusion of benefit estimation, problems related to cost estimation, conditional selection of policy instrument, decision of proper size of budget, additional cost) as an analytical framework.We found that except exclusion of benefit estimation, all disputed points could be regarded as technical problems in implementing the regulatory budget and identified as solvable problems. We also found that exclusion of benefit estimation has been at the center of application of regulatory budget and regarded as a selective problem of regulatory value between efficiency and equality. This results suggest that programs or institutions for regulatory reform be designed to strike a balance between efficiency and equity.

The Application of Quantitative Research in Developing Nursing Theory : An Example of Survey Study(Relationships among Health Locus of Control, Self-Efficacy, Self-Care, and Subjective Well-Being in the Elderly with Hypertension)

Chen, Yuh-Min 경희대학교 2001 INTERNATIONAL SYMPOSIUM ON EAST-WEST MEDICINE Vol.2001 No.1

The purpose of this study was to examine and identify relationships among health control orientation, self-efficacy, self-care behavior, and subjective well-being in the elderly with hypertension. The theoretical framework of this study, constructed by using theory synthesis, illustrates how several global factors and specific personal attributes, including health control orientation and self-efficacy, might influence self-care behavior and ultimately, subjective well-being. Six research questions evolving from this theoretical framework guided the study, which consisted of a sample of 121 noninstitutionalized elderly individuals with hypertension. Subjects were recruited through friends and senior activity centers. The packet of research instruments consisted of a demographic data sheet, the Health Control subscale of the Health Hardiness Inventory, the Exercise of Self-Care Agency, and the Index of Well-Being. Correlations and multiple regressions were the principal statistics used for data analysis. In general, the findings support the relationships identified in the proposed framework. Health control orientation was highly correlated with self-efficacy and self-care. Self-efficacy was also highly correlated with self-care. Health control orientation, self-efficacy, and self-care were all moderately associated with subjective well-being. Hierarchical repression showed that health control orientation and self-efficacy explained 39% of the variance in self-care. Hierarchical regression showed that health control orientation and self-efficacy accounted for 22% of the variance of subjective well-being, and the entry of self-care significantly increased the variance by 5%. This study examined components of the guiding theoretical framework. In general, the findings support the relationships identified in this model. However, implications for extension of knowledge include further testing of the proposed model before recommending specific nursing interventions.

통합재난관리이론의 분석적 해석 -재난관리체계 설계에의 정책적 함의--

여차민 ( Cha Min Yuh ) 한국정책학회 2014 韓國政策學會報 Vol.23 No.4

본 연구는 우리나라 재난관리체계의 토대를 이루고 있는 통합재난관리의 논거를 분석적으로 해석하여 재난관리체계 설계를 위한 정책적 함의를 도출하는 것을 목적으로 한다. 이에 본 연구에서는 기존문헌 검토를 통해 재난의 유사성, 재난발생 단계별 관리의 이점, 분산관리의 비효율성, 단일 총괄조직의 필요성 등을 통합재난관리의 논거로 정리하고 이를 분석적으로 해석하였다. 그리고 이를 다시 종합적으로 토론하여 정책적 함의를 도출한 후, 국민안전처 신설 및 오룡호 침몰사고 사례에 적용하여 그 유용성을 확인하였다. 정책적 함의의 내용은 다음과 같다. 첫째, 재난관리체계의 설계 시 기계적 재난관리 원칙을 적용하기 보다는 재난의 특성과 재난발생 단계의 가변성을 고려하여야 한다. 둘째, 통합재난관리가 대응에 최적화된 체계임을 감안하여 재난관리체계 설계 과정에서 다양한 재난이론 및 패러다임을 수용하여야 한다. 마지막으로 통합재난관리가 역사적?정치적 산물이라는 점에서 우리나라 재난관리체계의 역사적?제도적 맥락을 복합적으로 고려하여 재난관리체계를 설계하여야 한다. Since the Sewol ferry disaster, Criticisms proposed on disaster management system in Korea might be showing the necessity of profound analysis and interpretation on IEM(Integrated Emergency Management) which has become the foundation of disaster management system in Korea. This study aims at suggesting policy implications for designing a disaster management system by analytically interpreting the rationales for IEM which is somewhat normative. For this purpose, this study identified five rationales(such as similarity among types of disasters, benefits of 4 phase disaster management, inefficiency of diversified management, necessity of comprehensive agency) for IEM through literature review and suggested policy implications as followings by analytically interpreting these five rationales and comprehensively debating on the outcomes of the interpretation. Firstly, the government should consider the characteristics of disasters and the variableness of disaster phases rather than utilize the principles of disaster management by rote. Secondly, various theories and paradigms on disaster management need to be taken in the process of designing the disaster management system, considering that IEM is an optimal system especially to response phase. Finally, administrative, political, and historical characteristics in Korea should be counted in when designing the disaster management system, considering that IEM is the product of historical and political conditions of a country.

레트로 디자인 트렌드의 주기 특성 분석 -소비자 동향과 시각적 사례를 캔디자인을 중심으로-

여혜민 ( Hea-min Yuh ),손원준 ( Won-jun Son ) 한국디자인트렌드학회 2019 한국디자인포럼 Vol.24 No.3

연구배경 레트로는 계속적으로 이어져 오는 하나의 트렌드로서 현재에는 뉴트로(New-tro)라 하여 새로운(New) 레트로(Retro)의 움직임이 디자인 분야에서 활발하게 나타나고 있다. 이러한 레트로 트렌드 현상은 소비자의 감성과 경제적, 사회적 배경과도 많은 연관이 있는 것으로 사료된다. 따라서 본 연구에서는 레트로가 나타난 배경과 주기를 분석하고자 한다. 이를 통해 향후 레트로 디자인으로 이용할 수 있는 과거시대 범위를 제시하고 디자인 주기에 대한 학문적 연구에 초석을 다지는 데 기여하고자 한다. 연구방법 지금까지 나타난 레트로 디자인의 연대별 시각적 사례를 토대로 먼저 레트로 디자인의 주기를 고찰하고 레트로 경향이 나타나게 된 배경을 분석하였다. 이어서 본 논문은 소비자의 감성에 따른 레트로 디자인이 동일한 주기 형태로 나타나는지 분석하기 위해 SD(Semantic Differential Method) 기법으로 감성 평가를 실시하였다. 연구결과 사례에서 나타난 레트로 디자인의 시대적 범위는 시대가 흘러감에 따라 변화된 것을 알 수 있었다. 또한, 각 시대별 캔 디자인에 대한 감성평가결과에서는 두 연대의 디자인에 대해 실험대상자들은 유사한 감성을 나타냈다. 1970년대 1990년대 디자인에 대해서는 따뜻하고 친숙한 느낌을 나타냈고, 1960년대와 2010년대 디자인에 대해서는 차갑고, 어색한 느낌을 나타냈다. 또한 SD 기법에 의한 감성 평가 결과와 실제 사례를 비교해 봤을 때, 유사한 감성을 나타내는 시대가 레트로 디자인으로 불러오기 적합한 시대라고 유추할 수 있었다. 결론 캔 디자인 감성평가에서 서로 다른 두 시대가 유사한 감성을 나타낸 것으로 보아, 시대는 다르지만 감성이 맞는 ‘레트로 시대’가 있는 것으로 사료된다. 허나 한정된 표본으로 모든 디자인 분야의 레트로가 동일한 주기로 흘러간다고 단정하기는 이르다. 동일 주기성을 분석하기 위해서는 향후 더욱 확대된 시대적 범위와 더 광범위한 디자인 분야에서 주기를 더욱 깊이 조사하고 분석할 필요가 있다. Background Currently, Retro is being actively applied in the field of design as a called Neutro (New-Retro). This retro trend phenomenon seems to be related to consumers' emotions and economic and social backgrounds. Therefore, this study want to analyze the background and cycle of retro. Through this will be presented the range of time that can be reappeared by retro design in the future and be contributed to the foundation of academic research on the design cycle. Methods Based on the visual examples of retro design so far, first of all, this study analyzed the cycle of retro design and analyzed the background in which retro trends appeared. To the next, this paper conducted an emotional evaluation by the SD(Semantic Differential Method) technique to analyze the relationship between consumers' emotions and retro trends. Result In the case, the period of retro design showed that the period changed. Also, in the emotional evaluation results of the can design of each age, the experimental subjects showed similar emotions to the designs of the two age groups. In the 1970s and 1990s, the design was warm and familiar, and the designs in the 1960s and 2010s were cold and awkward. Also, when comparing the results of emotional evaluation by SD method and the actual cases, it can be seen that the era that shows similar emotion is suitable for retro design Conclusion As two different eras show similar emotions, it seems that there are 'Retro periods' which is different in period but similar emotional. However, it is too early to conclude that Retro design in all design areas will flow in the same cycle with limited specimens. Therefore, in order to analyze the same cycle of Retro, future studies will need to further investigate and analyze Retro Cycle for different ages in the larger and more extensive design areas.

[Free Paper] Clinical Significance of Neck Lymph Node Metastasis in Papillary Thyroid Carcinoma According to Size of Metastasis

Jung Min Lee,Sang Beom Seo,You Jin Lee,Eun Kyung Lee,Yuh-Seog Jung,Jun Sun Ryu,Seog-Yun Park,Tae Hyun Kim,Seok-Ki Kim,Tae-Sung Kim,Ki-Wook Chung 대한외과학회 2011 대한외과학회 학술대회 초록집 Vol.2011 No.11

[P5-29] Quality Characteristics of Makgeolli added with Black Garlic Extract and Black Garlic

Gyoung-Min Kim,Yuh-Ah Kim,Hwan-Sik Yoon,Jung-Hye Shin,Nak-Ju Sung 한국식품영양과학회 2010 한국식품영양과학회 학술대회발표집 Vol.2010 No.10

재발성 비호즈킨림프종에서 말초혈액조혈모세포이식의 결과

한성민,최신,유영진,김성록,한태희 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.2

Objective: This study is aimed to assess the effectiveness and safety of the autologous stem cell transplantation for patients with relapsed aggressive non-Hodgkin's lymphoma(NHL). Methods and Materials: We performed a retrospective analysis of 4 patients with relapsed aggressive NHL who undergone the autologous stem cell transplantation from the Inje University Sanggyepaik hospital. Results: All three patients with diffuse large B cell NHL have been in disease-free status without evidence of relapse for 5∼13 months after transplantation. A patient with extranodal NK/T cell lymphoma expired due to treatment related complications. Conclusion: High dose chemotherapy with autologous peripheral blood stem cell trar splantation(PBSCT) is an effective treatment for relapsed diffuse large B cell lymphoma.

인터넷 쇼핑몰에서의 소비자의 위험지각과 정보탐색에 관한 연구

신민경 ( Min Kyung Shin ),정순희 ( Soon Hee Joung ),여윤경 ( Yoon Kyung Yuh ) 대한가정학회 2004 Human Ecology Research(HER) Vol.42 No.9