Microfluidic generation of Prussian blue-laden magnetic micro-adsorbents for cesium removal

Kang, Sung-Min,Rethinasabapathy, Muruganantham,Hwang, Seung Kuy,Lee, Go-Woon,Jang, Sung-Chan,Kwak, Cheol Hwan,Choe, Sang-Rak,Huh, Yun Suk Elsevier 2018 CHEMICAL ENGINEERING JOURNAL -LAUSANNE- Vol.341 No.-

<P><B>Abstract</B></P> <P>Here, we designed and synthesized a recoverable multifunctional adsorbent using a microfluidic reaction system and evaluated the removal performance of the smart adsorbent toward radioactive cesium as a model sample. Prussian blue-laden magnetic micro-adsorbents (PB-MNPs-MAs) with uniform morphology and monodispersity were generated via two-step sequential procedures using a glass capillary microfluidic system, followed by chemical co-precipitation with a high production rate. The cesium removal efficacy of the PB-MNPs-MAs was analyzed based on Langmuir and Freundlich isotherms by controlling adsorption parameters such as adsorbent size, initial cesium concentration, and contact time. The adsorption isotherm of the PB-MNPs-MAs was better fitted to the Langmuir model with a maximum cesium adsorption capacity of 58.73 mg g<SUP>−1</SUP>, which was 40% higher than that of macro-adsorbents in a dynamic magnetic field. This result can be attributed to their large specific area, which increased the kinetic rate of cesium adsorption and achieved saturation within 20 min. Additionally, the PB-MNPs-MAs were recovered from wastewater within 5 s under a static magnetic field, indicating their great potential for magnetic actuation. We believe that our PB-MNPs-MAs can encapsulate nano-functional adsorbents and prevent actuation, making them promising for environmental remediation and especially for removal of radionuclides.</P> <P><B>Highlights</B></P> <P> <UL> <LI> PB-MNPs-MAs were generated in microfluidic device using chemical co-precipitation. </LI> <LI> The prepared PB-MNPs-MAs are monodispersed with uniform morphology. </LI> <LI> PB-MNPs-MAs exhibited high Cs adsorption capacity (58.73 mg g<SUP>−1</SUP>). </LI> <LI> 100% recovery of PB-MNPs-MAs is possible under static magnetic field after Cs adsorption. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

Moclobemide의 항우울 효과에 대한 평가

이귀행,박민철,노승호,백영석,이상열,김재현 圓光大學校 醫科學硏究所 1996 圓光醫科學 Vol.12 No.2

Eighteen patients took Moclobemide for 6 weeks, who had been diagnosed as major depression based on DSM-Ⅲ-R and had had more than 16 points on the Hamilton Depression Rating Scale. After medication of Moclobemide, they were evaluated by the Hamilton Depression Rating Scale and in terms of sleep, vigilance, performance, social interactions and drive. The results were as follows ; 1. The average dosage of Moclobemide was 400±89 ㎎. 2. Antidepressant effect were checked on the all items of the Hamilton Depression Rating Scale and prominent on the items of work and activities, insomnia, suicide, somatic symptoms. 3 There were obvious changes of the antidepressive effect by the evaluation of the doctors and patients at 4 weeks after the medication of Moclobemide. 4. In the patients, 61% had positive effects on the sleep. 94% no negative effects on the vigilance. Nobody has negative effects on the social interactions and drive. 5. Side effects or physical disturbances induced by Moclobemide were not found. According to these results, it seemed that Moclobemide had clear antidepressant effects, few negative effects on the life of day time, positive effects on the sleep and somatic symptoms.

알콜 및 임신오조에 의한 Wernicke-Korsakoff 증후군 2례

김훈,이귀행,박민철 圓光大學校 醫科大學 神經精神科學敎室 1994 圓光精神醫學 Vol.10 No.1

We reported a case of Wernicke-Korsakoff's syndrome which was consultated due to psychiatric symptoms by severe hyper-emesis gravidarum and a case of Wernicke-Koraskoff's syndrom which was diagnosed and treated due to chronic alcohol drinking. Wernicke-Korsakoff's syndrome is not rarely experienced in psychiatric settings, and early diagnosis and adequate treatment is much important in clinical prognosis of that illness. His detailed clinical features, etiologies and treatments are reported here with a brief review of literatures.

쌍태아에서 제 1태아의 분만 후 제 2태아의 지연분만 : 중례보고

김주환,서민정,유희정,노권일,조대현,박정규,이정헌,조성남,손영수 朝鮮大學校 附設 醫學硏究所 2005 The Medical Journal of Chosun University Vol.30 No.3

With the widespread use of fertility medications and techniques of in vitro fertilization, multiple gestation has become epidemic in modern obstetric practice. Delivery of the initial fetus in a multiple gestation usually is followed by delivery of the subsequent fetus or fetuses shortly thereafter. However in rare circumstances, the delivery is delayed for days due to disappearance of uterine contraction after delivery of the first fetus. When uterine activity ceases after the delivery of the first neonate, a policy of nonintervention may be considered in case of an immature or very premature delivery, in order to achieve a gestational age for the remaining fetus(es) more compatible with neonatal survival. We report a case of twin gestation with prolongation of the delivery interval between the twins for 46 days.

정신분열병 환자의 환시에 관한 임상적 연구

이상열,소광,이귀행,박민철 大韓神經精神醫學會 1997 신경정신의학 Vol.36 No.1

환시가 있는 정신분열병 환자가 어떻게 환시를 지각하고 있는지 이해하고 그들의 정신병리를 파악하여 효과적인 평가 및 치료에 도움을 주고자 본 연구를 시행하였다. 1991년 3월 1일부터 1992년 2월 28일 까지 DSM-III-R의 진단기준에 따라 정신분열병으로 입원한 환자 중 현재 지각하고 있는 환시를 그린 환자 40명을 대상으로 환시의 의미와 내용, 환시에 대한 정서적 반응 및 행동을 조사하였다. 또한 환시군과 대조군과의 간이정신상태검사와 간이정신평정척도를 비교하였으며, 환시의 의미와 환자의 망상 형태사이의 상관성, 환시에 대한 믿음의 강도, 환시의 빈도, 일회 삽화기간과 간이정신평정척도와의 상관성, 환시군의 간이정성평정척도 각 항목간의 상관성을 조사하였으며 결과는 다음과 같다. 1) 지각하고 있는 환시의 대상은 사람의 형태를 지닌 신화적인 인물, 의미는 피해적, 위치는 일상적 시야 범위 내의 근접거리, 빈도는 일주일에 한번 미만, 일회 삽화기간은 1∼5분, 정서적 반응은 부정적 반응, 환시에 대한 행동은 언어적 행동 또는 제한된 신체적 행동이 가장 많았다. 2) 환시의 의미와 망상의 내용사이에는 정적인 상관관계가 있었다. 3) 환시군은 환시 및 환각이 없는 군에 비해 불안, 환각적 행동, 비일상적 사고내용이 유의하게 많았다. 4) 환시 사실성에 대한 믿음의 강도와 환각 행동, 일회 삽화기간과 불안, 긴장, 운동성 지연 간에 정적인 상관이 있었다. 5) 환시군에서 간이 정신평정 척도상 환각적 행동항목과 불안, 환각적 행동과 매너리즘과 기묘한 자세취하기, 환각적 행동과 흥분, 환각적 행동과 운동성 지연에 각각의 정적인 상관이 있었다. 또한 운동성 지연과 긴장감, 무딘 감정과 긴장감, 감정적으로 움추러듬과 긴장감 사이에 각각 정적인 상관이 있었다. 본 연구의 결과들은 정신분열병 환자가 환시를 실제로 어떻게 지각하고 있는가를 임상가가 평가해야 하는 필요성을 나타내고 있다. Objective : The purpose of this study was to investigate actual visual hallucinations as perceived by 40 schizophrenic patients and, subsequently, to explore their psychopathology in order to assist clinicians in more effectively evaluating and treating the visual hallucination. Methods : With the authors' guidance, the content and meaning of pictures drawn, according to their perceptions, by 40 schizophrenic patients were evaluated in conjunction with an examination of the patient's emotional reaction and associated behavior. The results from the visual hallucination group were analyzed and then compared with non-visual hallucinatory control group using the Brief Psychiatric Rating Scale(BPRS). On this basis, the authors investigated the correlations between patients' strength of confidence in visual hallucination, frequency of visual hallucination, mean duration of an episode and the score of BPRS, and the correlation between meaning of visual hallucination and the type of patient's delusion. Finally the authors attempted to derive correlation among the items of BPRS. Results : 1) The content of visual hallucination was mostly non-human and mythologically exhibiting anthropomorphic qualities while its meaning was frequently persecutory. In addition, the visual hallucinations experienced by the subjects were most often close to or within the patients' ordinary visual range with mean duration of hallucinatory episodes ranging from 1 to 5 minutes. The most frequent reaction of patients is a negative emotional response and the most frequent overt behavior was either verbal or restricted physical activity. 2) There was a positive correlation between the meaning of the visual hallucination and the type of patients' delusion. 3) The group having visual hallucinations had more frequent anxiety, hallucinatory behavior and unusual thought content compared to the non-visual hallucination group. 4) There were positive correlations between patients' strength of confidence in visual hallucination and hallucinatory behavior and among anxiety, tension, motor retardation and mean duration of episodes of visual hallucination. 5) There were positive correlations between hallucinatory behavior and anxiety, hallucinatory behavior and mannerism and posturing, hallucinatory behavior and excitement, and hallucinatory behavior and motor retardation. Also, there were positive correlations between motor retardation and tension, blunted affect and tension, and between emotional withdrawal and tension among each item of BPRS in the visual hallucination group. Conclusion : In this study of visual hallucinations in schizophrenics, the authors concluded that it is helpful for clinicians to evaluate how schizophrenic patients experience their visual hallucination.

정신분열증 환자와 우울증 환자의 MMPI-2 프로파일

고윤화,손용훈,윤정흠,오상우,이귀행,박민철 圓光大學校 醫科學硏究所 2008 圓光醫科學 Vol.23 No.2

Background: Minnesota multiphasic personality inventory-2(MMPI-2) is superior to its predecessor in differential diagnosis. this study was to investigate MMPI-2 profiles of the patients with schizophrenia and depression and to discriminate among two groups. Methods: The sample consisted of 35 patients with schizophrenia(male 24, female 11), 35 patients with depression(male 18, female 17) diagnosed by the diagnostic and statistical manual of mental disorders(DSM-IV) for schizophrenia & depression at department of neuropsychiatry in WonKwang University from January 2005 to December 2007. The data from the results were analyzed statistically by t-test and discriminant analysis. Results: The results were as follows. First, according to t-test results the comparison of schizophrenia patients and depression patients in MMPI-2 among two groups showed significant differences; the validity scales: F, F(P); The clinical scales: D, Pa; The restructured clinical scales: Rcd(dem), RC4, RC6, RC8; The content scales: ANX, DEP, BIZ; The supplementary scales: AGGR, PSYC, Mt, GF, O-H. Second, as a results discriminant analysis, BIZ, D were significant predictors in distinguishing patients with schizophrenia from patients with depression. Third, probability to be discriminated schizophrenia in schizophrenia was 91.4%, probability to be discriminated depression in depression was 85.7%. Conclusion: Finally, we remind readers that although the MMPI-2 may prove to be useful in the task of differential diagnosis, it should be used only in combination with other patient information. 배경: MMPI-2는 감별진단에서 기존의 MMPI 보다 더 우수하다. 본 연구는 정신분열증 환자와 우울증 환자의 MMPI-2 프로파일과 두 집단을 판별하는 연구를 하였다. 방법: 2005년 1월부터 2007년 12월까지 원광대학교 병원 신경정신과에서 정신분열증과 우울증으로 진단된 정신분열증 환자 35명(남성 24명, 여성 11명), 우울증 환자 35명(남성 18명, 여성 17명)이 본 연구에 참여하였다. 자료는 t-검증과 판별분석으로 분석하였다. 결과: 결과는 다음과 같다. 1. t-검증 결과, 두 집단간 유의미한 차이를 보인 척도들로는 타당도 척도에서 F, F(P) 척도, 임상척도에서 D, Pa, 척도, 재구성 임상척도에서 Rcd(dem), RC4, RC6, RC8척도 였다. 내용척도에서는 ANX, DEP, BIZ척도 였으며 보충척도에서는 AGGR, PSYC, MT, GF O-H척도 였다. 2. 판별 분석 결과로서, 정신분열증과 우울증을 구별하는데 가장 유의한 예언요소는 BIZ, D척도로 나타났다. 3. 판별함수를 통한 진단율은 정신분열증을 정신분열증으로 판별해주는 정확도는 91.4%였고, 우울증을 우울증으로 판별해주는 정확도는 85.7%였다. 결론: 본 연구 결과를 통해서 MMPI-2가 두 집단을 감별하는데 유용하다고 증명되었을지 모르지만 더욱 정확하게 감별하기 위해서 환자의 기타 정보를 사용해야 할 것이다.

교환기용 PCM 신호획득시스템을 이용한 음성분석

장민규(Min-kuy Zang),송성용(Sung-yong Song),윤달환(Dal-hwan Yoon) 대한전자공학회 1997 대한전자공학회 학술대회 Vol.1997 No.11

Measurement of Human Joints based on Korean Cadaver CT Image and Concept Design of Drug Delivery Device

Tae-Min BYUN,Cheol-Woong KO,Sang-Kuy HAN,Keyoung-Jin CHUN,In-Hoon JANG 대한인간공학회 2014 대한인간공학회 학술대회논문집 Vol.2014 No.11

지적장애 학생의 축구활동 참여가 사회성에 미치는 영향

송민기 ( Min Ki Song ),노형규 ( Hyoung Kuy Roh ) 한국지적장애교육학회(구-한국정신지체아교육학회) 2010 지적장애연구 Vol.12 No.3

정치적 관점에서 본 관우(關羽) 신격화(神格化)의 역사적(歷史的) 변모양상 고찰

배규범 ( Kuy Beom Bae ),민관동 ( Kwan Dong Min ) 경희대학교 비교문화연구소 2016 비교문화연구 Vol.42 No.-

본고는 蜀漢의 武將에서 출발하여 神으로 추앙받고 있는 관우의 생명력을 역대 왕조의 정치적 측면에서 찾았다. 관우는 魏晉南北朝 시대에는 일개 장군으로 묘사되었지만, 隋唐 시대를 거치며 武成王廟 從祀를 통해 국가 祀典에 편입되었고, 다시 宋元시대에는 ‘侯’에서 ‘公’으로, 다시 ‘公’에서 ‘王’으로 신분의 급상승을 이루었다. 관우신격화가 절정에 이른 明淸 시대에 이르면, ‘王’을 넘어 ‘帝’로 등극하면서 三界를 통섭하는 최고의 권능을 부여받게 된다. 그는 백성에서부터 사대부에 이르기까지 생활신앙과 도덕 정신에 영향을 미쳤고, 결국은 정신적 守護神으로 존재할 수 있었다. 역사상 통치자가 關羽에게 내린 封號는 다양했지만, 그 속에는 국가의 재난 해소와 봉건통치의 유지와 보호라는 정치적 필요성이 깔려 있었다. This paper is an attempt to look up the life of Guanyu who was a sainted warrior of Shu Han(蜀漢) and later, was revered as God, especially focusing on the Political perspective of Chinese Dynasty. People represented Guanyu as the general during the Wei Jin Southern and Northern Dynasties(魏晉南北朝), however, throughout the Su-Dang Dynasty(隋唐), Guanyu was Honored in the Wuchengwangmiao(武成王廟) then, was promoted from Hou(侯) to Gong(公), Gong(公) to King(王) in the Song-Yuan Dynasty(宋元). In the Ming-Qing Dynasty(明 淸) when the deification of Guanyu was proceeded most positively, he became a Di(帝) over a King and was endowed with the power over the Three Worlds(三界). He had an influence on nobility as well as the people in Folkbelief over Moral Spirits, and consequently rose through the ranks to become the spiritual guardian. The rulers gave him various names(封號) celebrating the life and work of Guanyu, In fact, they showed interests in the Belief of Guanyu as they attempted to establish an ideological base for the solution of the national disaster and maintenance of feudal system which came to the fore along with the reinforcement for emperor’s power.