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Kim, Sun Jie,Kim, Wook Hyun,Lee, Chang-Hyun,Kim, Hwa-Min,Kang, Cheon Su,Han, Yoon Soo Informa UK (TaylorFrancis) 2017 MOLECULAR CRYSTALS AND LIQUID CRYSTALS - Vol.651 No.1
<P>Effects of sodium ethanesulfonate (SES) adsorbed on photoelectrode surface on the performance of dye-sensitized solar cells (DSSCs) was investigated. SES-modified photoelectrode was prepared by soaking the TiO2 film to an aqueous SES solution for 20 min. The DSSC with SES-modified TiO2 layer showed an increase in open circuit voltage (V-oc), short circuit current (J(sc)) and fill factor (FF), resulting in a power conversion efficiency of 11.20%, compared to that of reference device with bare TiO2 (10.21%). Electrochemical impedance spectroscopy and open circuit voltage decay measurements revealed that the SES modification of TiO2 surface led to a longer electron lifetime by the suppression of the interfacial charge recombination between photo-injected electrons and I-3(-) ions, resulting in an increase in J(sc) and V-oc, compared with those of a reference device without surface modification.</P>
이정규,전지현,김민정,이규재,김한겸,조현득,채양석 大韓法醫學會 1999 대한법의학회지 Vol.23 No.2
Although it is known that hypothyroidism can cause cardiac dysfunction, it is very hard to find a case report on sudden death due to hypothyroidism. There are only two reported cases on mediline; one is about a 15-year-old girl who died suddenly of Hashimoto's thyroiditis and the other is about a 31-year-old man who also died suddenly of hypothyroidism associated with chronic lymphocytic thyroiditis. Recently we found a young woman who unexpectedly died while she was sleeping. She was diagnosed as hypothyroidism when she went to hospital about a month before she died. At autopsy there were roughly four abnormal findings; Hashimoto's thyroiditis, mild chronic active hepatitis, diverticulosis and accessory spleen. Trace of chlorpheniramine was detected in gastric remains and blood alcohol level was 0.37 percent. To our knowledge, this is the first case reporting sudden and unexpected natural death associated with hypothyroidism in Korea.
자동차 이중전원 시스템을 위한 새로운 양방향 ZVS CUK 컨버터
이성룡,이수원,고성훈,문제민 국립7개대학공동논문집간행위원회 2004 공업기술연구 Vol.4 No.-
Currently, to overcome the limit of a 14V power supply system and to enhance the stability of this system high and to make the fuel efficiency better, a research development of a 42V power supply system is actively the progress. As an intermediate step to change into an unity power supply system, a 42V/14V dual power supply system uses a DC/DC Converter as one of structure elements. Considering the main electric power sources in the next generation of the car is a 42V system, a 14V power supply system has advantages as follows : to be managed efficiently and to increase the redundancy at start, to jump start with any vehicles, etc. We need the introduction of a bi-directional converter that can flow the energy each other in a dual 42V-12V system. This paper proposed the ZVS bi-directional CUK DC/DC converter which decrease the weight with the size of the DC/DC Converter and minimize the loss when the switching happen. In this paper, a circuit design method and an action principle of the circuit was proposed. To verify the proposed circuit, a comprehensive evaluation with theoretical analysis, simulation results is presented.
Molecular phylogenetic study of Arca boucardi using metallothionein gene
Jie Eun Park,Se Won Kang,Hee-Ju Hwang,Dae Kwon Song,Min Kyu Sang,Hye Rin Min,Jong Min Chung,Hee Cheol Ha,Hyun Jun Lee,Chan Eui Hong,Hong Seog Park,Yeon Soo Han,Jun Sang Lee,Yong Seok Lee 한국수산해양기술학회(구 한국어업기술학회) 2016 한국수산해양기술학회 학술발표대회 Vol.2016 No.10
Min, Se Hee,Kong, Sung Hye,Lee, Jie-Eun,Lee, Dong-Hwa,Oh, Tae Jung,Kim, Kyoung Min,Park, Kyong Soo,Jang, Hak Chul,Lim, Soo Elsevier 2017 Journal of diabetes and its complications Vol.31 No.10
<P><B>Abstract</B></P> <P><B>Objectives</B></P> <P>The relationship between the renin–angiotensin system (RAS) and diabetes has been studied for many years. However, studies that assessed RAS components comprehensively were limited. We hypothesized that serum RAS components, especially the effector peptide angiotensin-II, might be closely associated with glucose metabolism status and diabetic complications.</P> <P><B>Methods</B></P> <P>We investigated the association of individual RAS component with albuminuria in 407 subjects with normal glucose metabolism (NGM), prediabetes, or type 2 diabetes mellitus (T2DM). Anthropometric and biochemical parameters, including glucose homeostasis, albuminuria, and RAS-related parameters such as plasma renin activity (PRA), aldosterone, angiotensin-converting enzyme (ACE), and angiotensin-II levels, were measured.</P> <P><B>Results</B></P> <P>The mean±standard deviation (SD) age and body mass index were 57.1±11.1years and 24.7±3.3kg/m<SUP>2</SUP>, respectively. There were 54 subjects with NGM, 102 with prediabetes, and 251 with T2DM. The mean±SD angiotensin-II levels in these groups were 9.32±6.89, 12.89±10.39, and 17.00±15.28pg/mL, and the respective urinary albumin-to-creatinine ratios (ACRs) were 8.1±5.3, 13.3±17.3, and 30.7±51.9mg/g, which were significantly different among the groups. The serum angiotensin-II levels were correlated with levels of PRA, insulin resistance, C-reactive protein, and urinary ACR. Among RAS-related parameters, only the angiotensin-II level was significantly associated with urinary ACR after adjusting for relevant risk factors.</P> <P><B>Conclusions</B></P> <P>Angiotensin-II may play an important role in the development of albuminuria, particularly in subjects with impaired glucose metabolism.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Serum angiotensin-II concentration increases from prediabetic condition. </LI> <LI> Serum angiotensin-II was independently associated with urine albumin excretion after adjusting for multiple risk factors. </LI> <LI> Angiotensin-II plays a critical role in the pathophysiology of microvascular complications of diabetes. </LI> </UL> </P>
Molecular phylogenetic study of Arca boucardi using metallothionein gene
Jie Eun Park,Se Won Kang,Hee-Ju Hwang,Dae Kwon Song,Min Kyu Sang,Hye Rin Min,Jong Min Chung,Hee Cheol Ha,Hyun Jun Lee,Chan Eui Hong,Hong Seog Park,Yeon Soo Han,Jun Sang Lee,Yong Seok Lee 한국수산과학회 양식분과 2016 한국수산과학회 양식분과 학술대회 Vol.2016 No.10
HOXB5 Directly Regulates the Expression of IL-6 in MCF7 Breast Cancer Cells
Jie Min Kim,Ji-Yeon Lee,Myoung Hee Kim 대한의생명과학회 2017 Biomedical Science Letters Vol.23 No.3
HOX genes are transcription factors that play important roles in body patterning and cell fate specification during normal development. In previous study, we found aberrant overexpression of HOXB5 in breast cancer tissues and cell lines, and demonstrated that HOXB5 is important in regulation of cell proliferation, tamoxifen resistance, and invasiveness through the epithelial-mesenchymal transition (EMT). Although the relationship between HOXB5 and phenotypic changes in MCF7 breast cancer cells has been studied, the molecular function of HOXB5 as a transcription factor remains unclear. IL-6 has been reported to be involved in not only inflammation but also cancer progression, which is characterized by the increase of growth speed and invasiveness of tumor cells. In this study, we selected Interleukin-6 (IL-6) as HOXB5 putative downstream target gene and discovered that HOXB5 transcriptionally up-regulated the expression of IL-6 in HOXB5 overexpressing MCF7 cells. The upstream region (~1.2 kb) of IL-6 promoter turned out to contain several putative HOX consensus binding sites. Chromatin immunoprecipitation assay confirmed that HOXB5 directly binds to the promoter region of IL-6 and positively regulated the expression of IL-6. These data all together, indicate that HOXB5 promotes IL-6 transcription by actively binding to the putative binding sites located in the upstream region of IL-6, which enable to increase its promoter activity in MCF7 breast cancer cells.
( Min Wu Jie Tang ),( Xuerui Zhou ),( Dan Lei ),( Chaoyi Zeng ),( Hong Ye Ting Cai ),( Qing Zhang ) 한국미생물 · 생명공학회 2022 Journal of microbiology and biotechnology Vol.32 No.2
Continued fenvalerate use has caused serious environmental pollution and requires large-scale remediation. Dibutyl phthalate (DBP) was discovered in fenvalerate metabolites degraded by Citrobacter freundii CD-9. Coculturing is an effective method for bioremediation, but few studies have analyzed the degradation pathways and potential mechanisms of cocultures. Here, a DBPdegrading strain (BDBP 071) was isolated from soil contaminated with pyrethroid pesticides (PPs) and identified as Stenotrophomonas acidaminiphila. The optimum conditions for DBP degradation were determined by response surface methodology (RSM) analysis to be 30.9 mg/l DBP concentration, pH 7.5, at a culture temperature of 37.2℃. Under the optimized conditions, approximately 88% of DBP was degraded within 48 h and five metabolites were detected. Coculturing C. freundii CD-9 and S. acidaminiphila BDBP 071 promoted fenvalerate degradation. When CD-9 was cultured for 16 h before adding BDBP 071, the strain inoculation ratio was 5:5 (v/v), fenvalerate concentration was 75.0 mg/l, fenvalerate was degraded to 84.37 ± 1.25%, and DBP level was reduced by 5.21 mg/l. In addition, 12 fenvalerate metabolites were identified and a pathway for fenvalerate degradation by the cocultured strains was proposed. These results provide theoretical data for further exploration of the mechanisms used by this coculture system to degrade fenvalerate and DBP, and also offer a promising method for effective bioremediation of PPs and their related metabolites in polluted environments.