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( Francesca Ambrosi ),( Costantino Ricci ),( Deborah Malvi ),( Carlo De Cillia ),( Matteo Ravaioli ),( Michelangelo Fiorentino ),( Massimo Cardillo ),( Francesco Vasuri ),( Antonia D’errico ) 대한신장학회 2020 Kidney Research and Clinical Practice Vol.39 No.4
Background: We report the findings of a single Italian center in the evaluation of renal lesions in deceased donors from 2001 to 2017. In risk evaluation, we applied the current Italian guidelines, which include donors with small (< 4 cm, stage pT1a) renal carcinomas in the category of non-standard donors with a negligible risk of cancer transmission. Methods: From the revision of our registries, 2,406 donors were considered in the Emilia Romagna region of Italy; organs were accepted from 1,321 individuals for a total of 3,406 organs. Results: The evaluation of donor safety required frozen section analysis for 51 donors, in which a renal suspicious lesion was detected by ultrasound. Thirty-two primary renal tumors were finally diagnosed: 26 identified by frozen sections and 6 in discarded kidneys. The 32 tumors included 13 clear cell renal cell carcinomas (RCCs), 6 papillary RCCs, 6 angiomyolipomas, 5 oncocytomas, 1 chromophobe RCC, and 1 papillary adenoma. No cases of tumor transmission were recorded in follow-up of the recipients. Conclusion: Donors with small RCCs can be accepted to increase the donor pool. Collaboration in a multidisciplinary setting is fundamental to accurately evaluate donor candidate risk assessment and to improve standardized protocols for surgeons and pathologists.
Jo~ao Batista Silva Neto,Elita Fontenele Urano de Carvalho,Rafael Henrique Lazzari Garcia,Adonis Marcelo Saliba-Silva,Humberto Gracher Riella,Michelangelo Durazzo 한국원자력학회 2017 Nuclear Engineering and Technology Vol.49 No.8
Uranium tetrafluoride (UF4) is the most used nuclear material for producing metallic uranium by reduction with Ca or Mg. Metallic uranium is a raw material for the manufacture of uranium silicide, U3Si2, which is the most suitable uranium compound for use as nuclear fuel for research reactors. By contrast, ammonium uranyl carbonate is a traditional uranium compound used for manufacturing uranium dioxide UO2 fuel for nuclear power reactors or U3O8-Al dispersion fuel for nuclear research reactors. This work describes a procedure for recovering uranium and ammonium fluoride (NH4F) from a liquid residue generated during the production routine of ammonium uranyl carbonate, ending with UF4 as a final product. The residue, consisting of a solution containing high concentrations of ammonium (NH4+), fluoride (F-), and carbonate (CO3 2-), has significant concentrations of uranium as UO2 2+. From this residue, the proposed procedure consists of precipitating ammonium peroxide fluorouranate (APOFU) and NH4F, while recovering the major part of uranium. Further, the remaining solution is concentrated by heating, and ammonium bifluoride (NH4HF2) is precipitated. As a final step, NH4HF2 is added to UO2, inducing fluoridation and decomposition, resulting in UF4 with adequate properties for metallic uranium manufacture.