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Kim, Mi Jung,Ahn, Sung Jae,Fan, Kenneth L.,Song, Seung Yong,Lew, Dae Hyun,Lee, Dong Won Korean Society of Plastic and Reconstructive Surge 2019 Archives of Plastic Surgery Vol.46 No.6
Background As the indications for postmastectomy radiotherapy expand, innovative solutions are required to reduce operative complications and reconstructive failure after prosthetic breast reconstruction. In this study, we investigated the effectiveness of acellular dermal matrix (ADM) inlay grafts in preventing postoperative wound dehiscence of irradiated breasts in the context of prosthetic breast reconstruction. Methods A retrospective analysis was conducted of 45 patients who received two-stage prosthetic reconstruction and radiotherapy following mastectomy. An ADM graft was placed beneath the incisional site during the second-stage operation in 19 patients using marionette sutures, whereas the control group did not receive the ADM reinforcement. Patient demographics and complications such as wound dehiscence, capsular contracture, peri-prosthetic infection, cellulitis, and seroma were compared between the two groups. Results During an average follow-up period of 37.1 months, wound dehiscence occurred significantly less often in the ADM-reinforced closure group (0%) than in the non-ADM group (23.1%) (P=0.032). There was no significant difference between the two groups in relation to other complications, such as capsular contracture, postoperative infection, or seroma. Conclusions The ADM inlay graft is a simple and easily reproducible technique for preventing incisional dehiscence in the setting of radiotherapy after prosthetic breast reconstruction. The ADM graft serves as a buttress to offload tension during healing and provides a mechanical barrier against pathogens. Application of this technique may serve to reduce complications in prosthetic breast reconstruction after radiotherapy.
조현희 ( Hyun Hee Jo ),황성진 ( Sung Jin Hwang ),김미란 ( Mi Ran Kim ),김장흡 ( Jang Heub Kim ),유영옥 ( Young Ok Lew ),임용택 ( Yong Taek Lim ),김은중 ( En Jung Lim ),김진홍 ( Jin Hong Kim ) 대한산부인과학회 2005 Obstetrics & Gynecology Science Vol.48 No.3
목적: 제대혈 내의 렙틴 수치와 분만 진행 시간과의 연관성에 대해 분석한다. 연구 방법: 2004년 1월부터 2004년 6월까지 6개월간 가톨릭대학교 의과대학 부속 성모병원에서 분만했던 산모 84명을 대상으로 하여 제대혈 내 렙틴 수치를 조사하였다. 총 분만시간, 임신 전과 후의 몸무게, 신생아의 몸무게, 두위, 태반의 무게가 조사되었다. 총 분만 시간은 자궁경부가 3cm 개대된 순간부터 태반이 분리되는 순간까지를 계산하였다. 렙틴의 측정은 ELISA를 Objective: To evaluate the correlation of level of leptin in cord blood and duration of labor. Methods: Eighty-four pregnant women who had delivered during Jan. 2004-Jun. 2004. at the delivery unit of St. Mary`s Hospital of Catholic University Medical Col
제왕절개술 후 복벽반흔에 발생한 자궁내막증 환자에서 mesh를 이용한 복부근막재건술
김수미 ( Su Mi Kim ),김현경 ( Hyun Kyoung Kim ),남궁정 ( Jung Nam Kung ),송재연 ( Jae Yeon Song ),정인철 ( In Chol Jung ),조현희 ( Hyun Hee Cho ),권동진 ( Dong Jin Kwon ),유영옥 ( Young Oak Lew ),김은중 ( Eun Jung Kim ),김장흡 ( J 대한산부인과학회 2012 Obstetrics & Gynecology Science Vol.55 No.7
Endometriosis is defined by the presence of endometrial glands and stroma outside uterine cavity showing variable clinical symptoms under effect of estrogen. The occurrence rate of abdominal wall endometriosis after cesarean section is rare making diagnosis difficult. The case of a 36-year-old female presenting with the very painful mass and pain arising in the caesarean section scar is reported. The curable treatment of abdominal wall endometriosis is the surgical removal of all the pathological tissue, through a large excision. The involved fascia was widely excised and the abdominal wall was reconstructed using polypropylene mesh.
LT, Others : PE-127 ; The seroprevalence of hepatitis A virus antibody in Western Gyeongnam province
( Dong Hoon Lew ),( Ja Yoon Choi ),( Jeong Mi Lee ),( Yun Won Jo ),( Hyun Ju Min ),( Hong Jun Kim ),( Chang Yoon Ha ),( Hyun Jin Kim ),( Woon Tae Jung ),( Ok Jae Lee ) 대한간학회 2012 춘·추계 학술대회 (KASL) Vol.2012 No.-
Backgrounds: In recent years, the incidence of acute hepatitis A (HAV) has significant increase in South Korea. It is due to both improved socioeconomic conditions and decreased seroprevalence of immunoglobulin G anti-hepatitis A virus (IgG anti- HAV). Acute hepatitis A was epidemic primarily around the capital area but was not so prevalent in Gyeongnam province. We investigated the seroprevalence of IgG anti-HAV in Western Gyeongnam province. Subjects and Methods: We collected questionnaires composed of several items, including age, sex, history of hepatitis, history of anti HAV vaccination, type of residence, from those who visit Gyeongsang National University Hospital for the routine check up including IgG anti-HAV. From May 2011 to April 2012, 3000 subjects were enrolled, among them 2392 questionnaires from people living in Gyeongnam province was put to use for the final data analysis. Results: Among 2392 patients, 1389 (58.1%) were male and 1003 (41.9%) were female. Overall the seroprevalence of IgG anti-HAV was 83.3%. Older subjects had more increased seroprevalence of IgG anti-HAV than younger subjects, 3rd decade (8/98, 8.2%), 4th (278/515, 54%), 5th (733/801, 91.5%), 6th (696/700, 99.4%), 7th (228/228, 100%), 8th (50/50, 100%), respectively (p<0.001). Subjects who had lived in rural area showed an increase of seroprevalence of IgG anti-HAV (p = 0.001). Conclusion: People on their 20th`s or 30th`s living Gyeongnam province had more positive IgG anti-HAV rate than people living other regions. This partly explains the reason that acute hepatitis A was not so prevalent in Gyeongnam compared to the capital area and other provinces.
LT, Others : PE-127 ; The seroprevalence of hepatitis A virus antibody in Western Gyeongnam province
( Dong Hoon Lew ),( Ja Yoon Choi ),( Jeong Mi Lee ),( Yun Won Jo ),( Hyun Ju Min ),( Hong Jun Kim ),( Chang Yoon Ha ),( Hyun Jin Kim ),( Woon Tae Jung ),( Ok Jae Lee ) 대한간학회 2012 춘·추계 학술대회 (KASL) Vol.2012 No.1
Backgrounds: In recent years, the incidence of acute hepatitis A (HAV) has significant increase in South Korea. It is due to both improved socioeconomic conditions and decreased seroprevalence of immunoglobulin G anti-hepatitis A virus (IgG anti- HAV). Acute hepatitis A was epidemic primarily around the capital area but was not so prevalent in Gyeongnam province. We investigated the seroprevalence of IgG anti-HAV in Western Gyeongnam province. Subjects and Methods: We collected questionnaires composed of several items, including age, sex, history of hepatitis, history of anti HAV vaccination, type of residence, from those who visit Gyeongsang National University Hospital for the routine check up including IgG anti-HAV. From May 2011 to April 2012, 3000 subjects were enrolled, among them 2392 questionnaires from people living in Gyeongnam province was put to use for the final data analysis. Results: Among 2392 patients, 1389 (58.1%) were male and 1003 (41.9%) were female. Overall the seroprevalence of IgG anti-HAV was 83.3%. Older subjects had more increased seroprevalence of IgG anti-HAV than younger subjects, 3rd decade (8/98, 8.2%), 4th (278/515, 54%), 5th (733/801, 91.5%), 6th (696/700, 99.4%), 7th (228/228, 100%), 8th (50/50, 100%), respectively (p<0.001). Subjects who had lived in rural area showed an increase of seroprevalence of IgG anti-HAV (p = 0.001). Conclusion: People on their 20th``s or 30th``s living Gyeongnam province had more positive IgG anti-HAV rate than people living other regions. This partly explains the reason that acute hepatitis A was not so prevalent in Gyeongnam compared to the capital area and other provinces.
간세포암종에 대한 간동맥 화학색전술 후 발생한 급성호흡곤란증후군
조윤원,이정미,최자윤,유동훈,차라리,오혜원,김홍준,민현주,김현진,정운태,이옥재,하창윤,이선영 이화여자대학교 의과학연구소 2013 EMJ (Ewha medical journal) Vol.36 No.1
Transcatheter arterial chemoembolization (TACE) has become an effective alternative treatment strategy for patients with inoperable hepatocellular carcinoma (HCC). Although TACE is relatively safe, acute respiratory distress syndrome associated with pulmonary lipiodol embolism is a rare and potentially fatal complication. We report a rare case of acute respiratory distress syndrome after TACE for inoperable HCC. A 75-year-old man, with huge HCC in right lobe, was treated by TACE for the first time. Seven hours after uneventful TACE procedure, he felt dyspneic and his oxygen saturation recorded by pulse oximetry (SpO2) fell to 80% despite of applying non-rebreathing mask. He underwent mechanical ventilation with a protective ventilatory strategy. We experienced a case of acute respiratory distress syndrome after TACE for HCC.
Yun, In Sik,Lee, Mi Hee,Rah, Dong Kyun,Lew, Dae Hyun,Park, Jong-Chul,Lee, Won Jai Williams & Wilkins 2015 Plastic and reconstructive surgery Vol.136 No.1
BACKGROUND:: The regulation of apoptosis, proliferation, and migration of fibroblasts is altered in keloids. The 90-kDa heat shock protein (heat shock protein 90) is known to play a key role in such regulation. Therefore, the authors investigated whether the inhibition of heat shock protein 90 in keloid fibroblasts could induce apoptosis and attenuate keloid fibroblast proliferation and migration. METHODS:: The authors evaluated heat shock protein 90 expression in keloid tissues with immunohistochemistry. The authors used cell viability [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] assays and annexin V/propidium iodide staining for apoptosis, a wound healing model and cell tracking system to assess cell migration, and Akt Western blotting analysis in keloid fibroblasts after inhibition of heat shock protein 90 with 17-allylaminodemethoxygeldanamycin (17-AAG). RESULTS:: The expression of heat shock protein 90 in keloid tissues was significantly increased compared with normal tissues. The 17-AAG–treated keloid fibroblasts showed significantly decreased proliferation, promotion of apoptosis, and decreased expression of Akt. Furthermore, a dose-dependent decrease in cell migration was noted after 17-AAG treatment of keloid fibroblasts. The 17-AAG–treated keloid fibroblasts had less directionality to the wound center and migrated a shorter distance. CONCLUSIONS:: The authors confirmed that the inhibition of heat shock protein 90 in keloid fibroblasts could promote apoptosis and attenuate proliferation and migration of keloid fibroblasts. Therefore, the authors think that the inhibition of heat shock protein 90 is a key factor in the regulation of biological processes in keloids. With further preclinical study, the authors will be able to apply these results clinically for keloid treatment.