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        Comparison of superb microvascular imaging and shear wave elastography for assessing liver fibrosis in chronic hepatitis B

        Mesude Tosun,Hande Uslu 대한초음파의학회 2022 ULTRASONOGRAPHY Vol.41 No.2

        Purpose: The present study investigated the effectiveness and applicability of superb microvascular imaging (SMI) in determining the degree of liver fibrosis noninvasively in comparison with shear wave elastography (SWE).Methods: Ninety-eight consecutive patients with chronic hepatitis B who underwent ultrasound (US)-guided needle biopsy were examined using US combined with SMI and SWE. The predictive performance of the two US techniques in staging liver fibrosis and inflammation was compared with reference to the histological findings obtained from liver biopsy. The intraobserver and interobserver reproducibility of SMI in vascularity scores were evaluated.Results: SWE values and SMI vascular scores were statistically significantly different among fibrosis stages (χ<sup>2</sup>(3)=76.3, χ<sup>2</sup>(3)=81.5, P<0.001). The SWE and SMI models significantly predicted fibrosis stages separately, and SMI scores alone predicted fibrosis stages better than SWE values (50.1% for SWE, 63.5% for SMI, P<0.001). A model with both SMI scores and SWE values together explained 73.2% of variance in fibrosis stages. When other clinical and laboratory predictors were added to the model (81.5%, P<0.001), SWE values and SMI scores remained the main predictors of fibrosis stages. SWE and SMI were also applicable in predicting inflammatory grades, explaining 31% and 34% of variance, respectively, and 37.7% when used together (P<0.001).Conclusion: Both SWE and SMI had good diagnostic performance in determining the degree of liver fibrosis in chronic hepatitis B patients. The efficacy of SMI was better than that of SWE. SMI can improve diagnostic performance for staging liver fibrosis and shows potential for estimating necroinflammation of the liver.

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        Investigation of Shear Complex Modulus and Phase Angle Values of Short- and Long-term Aged Polymer Modified Bitumens at Different Frequencies

        Taner Alatas,Mesude Yilmaz,Necati Kuloglu,Mehmet Cakiroglu,Tacettin Geckil 대한토목학회 2014 KSCE JOURNAL OF CIVIL ENGINEERING Vol.18 No.7

        In this study, modified bitumens were prepared by mixing two types of Styrene-Butadiene-Styrene (SBS-D and SBS-M) and Ethylene-Vinyl-Acetate (EVA) with B 160/220 base bitumen 3% by weight. The short- and long-term aging processes were applied to base and modified binders with rolling thin film oven test and pressure aging vessel, respectively. Dynamic Shear Rheometer (DSR) test conducted at different temperatures and frequencies showed that while the shear complex modulus (G*) of unaged, short- and long-term aged binders reduced, the phase angle (δ) of those increased. The shear complex modulus values increased and the phase angle values decreased by the effect of aging and increase in frequency. The G*/sinδ values increased with the addition of modifiers to the base bitumen. Comparison of modifiers demonstrated that the effective modifier type shows variety according to frequency, temperature and aging conditions.

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        Novel Approach to Analytical Jitter Modeling

        Adnan Huremovic,Mesud Hadzialic 한국통신학회 2015 Journal of communications and networks Vol.17 No.5

        In this paper we propose an analytical model for jitter, wherein we implement the interrupted Poisson process (IPP) for incoming traffic. First, we obtain an analytical model for the jitter on one node with respect to the phase probabilities, traffic load, and tagged traffic share in the aggregate traffic flow. Then, we analyze N-node cases, and propose a model for end-to-end jitter. Our analysis leads to some fast-to-compute approximations that can be used for future network design or admission control. Finally, we validate our analytical results by comparing them with previous results for limit cases, as well as with event-driven simulations. We propose the use of our results as guidelines for jitter evaluation of real IP traffic.

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