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- 저자 : Mauverger (검색결과 2 건)
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Brun, Jean-Frederic,Varlet-Marie, Emmanuelle,Chevance, Guillaume,Pollatz, Marion,Fedou, Christine,de Mauverger, Eric Raynaud 한국유변학회 2014 Korea-Australia rheology journal Vol.26 No.2
We recently proposed a unifying hypothesis to reconcile unexpected findings in exercise hemorheology and the classical concepts of "hemorheologic fitness" and the "triphasic effects of exercise", based on the "healthy primitive lifestyle" paradigm. This paradigm assumes that evolution has selected genetic polymorphisms leading to insulin resistance as an adaptative strategy to cope with continuous low intensity physical activity and a special alimentation moderately high in protein, rich in low glycemic index carbohydrates, and poor in saturated fat. According to this protocol the true physiological picture would be that of an individual whose exercise and nutritional habits are close from this lifestyle, both sedentary subjects and trained athletes representing situations on the edge of this model. Unfortunately samples of people truly adhering to this ancestral lifestyle are hard to obtain. In order to address this picture we tried to compare databases obtained with our preceding published studies. As a model of the "healthy primitive lifestyle" we selected patients trained at low intensity (LI) and given an advice of protein intake around 1.2 g/kg/day. Results show a continuum for plasma viscosity which seems to be lower in athletes than LI-trained and even more sedentaries. When sedentary subjects become obese the most obvious characteristic is an increase in red blood cell (RBC) aggregation correlated to the size of fat stores. It is clear that 3 months of LI are not a perfect model of "healthy primitive lifestyle", but these data suggest that the most important effect of LI regular exercise is to decrease plasma viscosity and that sedentarity increases RBC aggregation mostly when it results in increased fat storage.
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Jean-Frédéric Brun,Emmanuelle Varlet-Marie,Guillaume Chevance,Marion Pollatz,Christine Fedou,Eric Raynaud de Mauverger 한국유변학회 2014 Korea-Australia rheology journal Vol.26 No.2
We recently proposed a unifying hypothesis to reconcile unexpected findings in exercise hemorheology andthe classical concepts of “hemorheologic fitness” and the “triphasic effects of exercise”, based on the “healthyprimitive lifestyle” paradigm. This paradigm assumes that evolution has selected genetic polymorphisms leadingto insulin resistance as an adaptative strategy to cope with continuous low intensity physical activity anda special alimentation moderately high in protein, rich in low glycemic index carbohydrates, and poor in saturatedfat. According to this protocol the true physiological picture would be that of an individual whose exerciseand nutritional habits are close from this lifestyle, both sedentary subjects and trained athletes representingsituations on the edge of this model. Unfortunately samples of people truly adhering to this ancestral lifestyleare hard to obtain. In order to address this picture we tried to compare databases obtained with our precedingpublished studies. As a model of the “healthy primitive lifestyle” we selected patients trained at low intensity(LI) and given an advice of protein intake around 1.2 g/kg/day. Results show a continuum for plasma viscositywhich seems to be lower in athletes than LI-trained and even more sedentaries. When sedentary subjectsbecome obese the most obvious characteristic is an increase in red blood cell (RBC) aggregation correlatedto the size of fat stores. It is clear that 3 months of LI are not a perfect model of “healthy primitive lifestyle”,but these data suggest that the most important effect of LI regular exercise is to decrease plasma viscosity andthat sedentarity increases RBC aggregation mostly when it results in increased fat storage.
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