지역고용 증진을 위한 독일의 지역고용서비스 정책

Matthias Schulze-Boing 한국노동연구원 2014 국제노동브리프 Vol.12 No.1

In vitro Stability of Heat Shock Protein 27 in Serum and Plasma Under Different Pre-analytical Conditions: Implications for Large-Scale Clinical Studies

Matthias Zimmermann,Denise Traxler,Elisabeth Simader,Christine Bekos,Benjamin Dieplinger,Mitja Lainscak,Hendrik Jan Ankersmit,Thomas Mueller 대한진단검사의학회 2016 Annals of Laboratory Medicine Vol.36 No.4

The effects of storage temperatures, repeated freeze-thaw cycles, or delays in separating plasma or serum from blood samples are largely unknown for heat shock protein 27 (HSP27). We evaluated (1) the imprecision of the HSP27 assay used in this study; (2) the in vitro stability of HSP27 in blood samples stored at 4°C for up to 6 hr with immediate and delayed serum/plasma separation from cells; and (3) the in vitro stability of HSP27 in blood samples stored at -80°C after repeated freeze-thaw cycles. The ELISA to detect HSP27 in this study showed a within-run CV of <9% and a total CV of <15%. After 4-6 hr of storage at 4°C, HSP27 concentrations remained stable when using serum tubes irrespective of sample handling, but HSP27 concentrations decreased by 25-45% when using EDTA plasma tubes. Compared with baseline HSP27, one freeze-thaw cycle had no effect on serum concentrations. However, plasma concentrations increased by 3.1-fold after one freeze-thaw cycle and by 7.3-fold after five freeze-thaw cycles. In conclusion, serum is an appropriate biological sample type for use in epidemiological and large-scale clinical studies.

Thermal Fingerprints for Computational Tasks - Benefits and Security Issues

Matthias Vodel,Marc Ritter,Wolfram Hardt 대한전자공학회 2017 대한전자공학회 학술대회 Vol.2017 No.1

Digital fingerprinting is used in several security-related domains to identify and track individual users or processes. In this paper, we introduce and discuss thermal fingerprinting as a novel approach to categorise computational tasks regarding its security impact and possible attack vectors. The concept of thermal fingerprinting monitors basic thermal sensor data from each server entity. The respective, characteristic curves are merged with additional general system information, such as CPU load behaviour, memory usage, and I/O characteristics. The result represents two-dimensional thermal patterns, which are unique and achievable. Besides the huge potential for energy savings, also security issues has to be analysed and considered.

2018년 독일 노동시장 및 노사관계 전망

Matthias Knuth 한국노동연구원 2018 국제노동브리프 Vol.16 No.2

Assessing the Impact of Trade Liberalization: The Case of Jordan

( Matthias Busse ),( Steffen Groning ) 세종대학교 경제통합연구소 2012 Journal of Economic Integration Vol.27 No.3

This paper assesses the impact of Jordan`s substantial trade liberalization over the last two decades. Using a gravity model, a large country sample, and a long time-series, we estimate the effects of various Free Trade Agreements (FTAs) and the World Trade Organization (WTO) accession on both Jordan`s exports and imports. Overall, we find that the impact has been rather small, as no statistically significant and robust impact on exports and imports can be found due to multilateral or preferential trade liberalization. However, there is one exception: the FTA with the United States of America has boosted Jordan`s exports to the US to a considerable degree.

Drive Signals for Maximizing the Velocity of Piezoelectric Inertia Motors

Matthias Hunstig,Tobias Hemsel 한국물리학회 2010 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.57 No.41

Piezoelectric inertia motors have a simple construction and are controlled by a single driving signal. This allows for miniaturization and low-cost production. One of the main questions to be answered during the design process of a piezoelectric inertia motor is which electrical excitation signal yields optimum motor characteristics. Three signals and their variants are widely used in the literature: sawtooth, parabolic and cycloidic signals. Within this paper, we propose to use a rigid body model of a simple inertia motor to predict the dependance of the motor characteristics on the movement pattern of the driving element. The advantages and the disadvantages of three different drive signals that maximize the motor velocity are discussed.

Pathogenesis-based therapy of disorders of cornification

( Matthias Schmuth ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.2

The Adjacent Vessel Sign on Breast MRI: New Data and a Subgroup Analysis for 1,084 Histologically Verified Cases

Matthias Dietzel,Pascal A.T. Baltzer,Tibor Vag,Aimee Herzog,Mieczyslaw Gajda,Oumar Camara,Werner A. Kaiser 대한영상의학회 2010 Korean Journal of Radiology Vol.11 No.2

Objective: The adjacent vessel sign (AVS) is a descriptor for differentiating malignant from benign breast lesions on breast MRI (bMRI). This investigation was designed to verify the previous reports on the diagnostic accuracy of AVS and to assess correlation between AVS, histopathological diagnosis, lesion size and lesion grade. Materials and Methods: This study was approved by the local ethical committee. Experienced radiologists evaluated 1,084 lesions. The exclusion criteria were no histological verification after bMRI and breast interventions that were done up to one year before bMRI (surgery, core biopsy, chemo- or radiation therapy). The native and dynamic contrast-enhanced T1-weighted series were acquired using standardized protocols. The AVS was rated positive if a vessel leading to a lesion could be visualized. Prevalence of an AVS was correlated with the lesions’ size, grade and histology using Chi-square-tests. Results: The AVS was significantly associated with malignancy (p < 0.001; sensitivity: 47%, specificity: 88%, positive-predictive-value [PPV]: 85%). Malignant lesions > 2 cm more often presented with an AVS than did those malignant lesions < 2 cm (p < 0.0001; sensitivity: 65%, PPV: 90%). There was no correlation of the AVS with the tumor grade. The prevalence of an AVS didn’t significantly differ between invasive lobular carcinomas versus ductal carcinomas. In situ cancers were less frequently associated with an AVS (p < 0.001). Conclusion: The adjacent vessel sign was significantly associated with malignancy. Thus, it can be used to accurately assess breast lesions on bMRI. In this study, the AVS was particularly associated with advanced and invasive carcinomas. Objective: The adjacent vessel sign (AVS) is a descriptor for differentiating malignant from benign breast lesions on breast MRI (bMRI). This investigation was designed to verify the previous reports on the diagnostic accuracy of AVS and to assess correlation between AVS, histopathological diagnosis, lesion size and lesion grade. Materials and Methods: This study was approved by the local ethical committee. Experienced radiologists evaluated 1,084 lesions. The exclusion criteria were no histological verification after bMRI and breast interventions that were done up to one year before bMRI (surgery, core biopsy, chemo- or radiation therapy). The native and dynamic contrast-enhanced T1-weighted series were acquired using standardized protocols. The AVS was rated positive if a vessel leading to a lesion could be visualized. Prevalence of an AVS was correlated with the lesions’ size, grade and histology using Chi-square-tests. Results: The AVS was significantly associated with malignancy (p < 0.001; sensitivity: 47%, specificity: 88%, positive-predictive-value [PPV]: 85%). Malignant lesions > 2 cm more often presented with an AVS than did those malignant lesions < 2 cm (p < 0.0001; sensitivity: 65%, PPV: 90%). There was no correlation of the AVS with the tumor grade. The prevalence of an AVS didn’t significantly differ between invasive lobular carcinomas versus ductal carcinomas. In situ cancers were less frequently associated with an AVS (p < 0.001). Conclusion: The adjacent vessel sign was significantly associated with malignancy. Thus, it can be used to accurately assess breast lesions on bMRI. In this study, the AVS was particularly associated with advanced and invasive carcinomas.

Parameter Identification and Model Validation for the Piezoelectric Actuator in an Inertia Motor

Matthias Hunstig,Tobias Hemsel 한국물리학회 2010 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.57 No.41

Piezoelectric inertia motors make use of the inertia of a slider to drive the slider by friction contact in a series of small steps which are generally composed of a stick phase and a slip phase. If the best electrical drive signal for the piezoelectric actuator in an inertia motor is to be determined, its dynamical behaviour must be known. A classic dynamic lumped parameter model for piezoelectric actuators is valid only in resonance and, therefore, is not suitable for modelling the actuator in an inertia motor. A reduced dynamic model is used instead. Its parameters are identified using a step response measurement. This model is used to predict the movement of the actuator in response to a velocity-optimized signal introduced in a separate contribution. Results show that the model cannot represent the dynamical characteristics of the actuator completely. For determining voltage signals that let piezoelectric actuators follow a calculated movement pattern exactly, the model can, therefore, only be used with limitations.

Towards Gendering Northeast Asian Traditional Security: The Cases of the USS Pueblo and Juche Policy

Matthias Maass 한국국방연구원 2014 The Korean Journal of Defense Analysis Vol.26 No.2

Since the conclusion of the uneasy armistice that halted the Korean War in 1953, security on the Korean Peninsula has remained unsettled. This has negatively impacted regional security dynamics, too. A major problem has been North Korean military provocations. South Korean and U.S. responses to such maneuvers have further contributed to regional instability. Using the case of the 1968 Pueblo Incident, the paper examines the context of military provocation and reaction with the focus on a suspected gender-bias in regional security affairs. The paper investigates Pyongyang’s motivation for initiating a crisis and Washington’s and Seoul’s responses to the provocation and applies a branch of International Relations Theory, Gender Studies, as its analytical framework. The conclusion is that all actors involved in the 1968 Pueblo Incident, especially North Korea’s leadership, initiated or preferred actions that were heavily gender-biased. Demonstrations of strength, independence, and victory were seen as the only ones appropriate, while alternative policies were seen as weak and defeatist. In 1968, conflict and conflict resolution can be properly explained as heavily gender-biased, which sheds new light on our understanding of North Korea’s motivation for the provocation, and South Korean and American responses.