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Sa,Sang-duk,Narita Masakuni 대한방사선 방어학회 1994 방사선방어학회지 Vol.19 No.2
방사선방호의 최적화 검토에 대하여 계층화 의사결정법에 의한 의사결정과정에 예시적 방법론이 제시되었다. ICRP Publ. 55의 우라늄 광산 환기시스템 결정사례의 방호데이터를 이용하여 주어진 방호선택대안 가운에 최적안을 도출하는 과정을 나타내었다. 이 AHP 방법은 방사선방호의 최적안 결정에 있어 방사선호 관리자 또는 의사결정자가 이해하기 쉽고 간단한 방법으로 판단된다. This study aims to introduce a prescriptive methodology to comprehensively support the analysis of decision process by the use of Saaty's Analytical Hierarchy Process for the optimization of radiation protection. The analytical Hierarchy Process for the optimization of radiation protection. The analytical process or the problem of selecting options among given protection alternatives is illustrated with the data of the uranium mine example in ICRP publ. 55. This technique, unlike other conventional selection method, is considered to provide a useful tool for the protection manager with respect to its ease of use and simplification in the choice of optimal alternative associated with radiological protection.
사상덕,Sa, Sang-Duk,Narita, Masakuni 대한방사선방어학회 1994 방사선방어학회지 Vol.19 No.2
방사선방호의 최적화 검토에 대하여 계층화 의사결정법에 의한 의사결정과정의 예시적 방법론이 제시되었다. ICRP Publ. 55의 우라늄 광산 환기시스템 결정 사례의 방호데이터를 이용하여 주어진 방호선택대안 가운데 최적안을 도출하는 과정을 나타내었다. 이 AHP 방법은 방사선방호의 최적안 결정에 있어 방사선방호 관리자 또는 의사 결정자가 이해하기 쉽고 간편한 방법으로 판단된다. This study aims to introduce a prescriptive methodology to comprehensively support the analysis of decision process by the use of Saaty's Analytical Hierarchy Process for the optimization of radiation protection. The analytical Hierarchy Process for the optimization of radiation protection. The analytical process for the problem of selecting options among given protection alternatives is illustrated with the data of the uranium mine example in ICRP Publ. 55. This technique, unlike other conventional selection method, is considered to provide a useful tool for the protection manager with respect to its ease of use and simplification in the choice of optimal alternative associated with radiological protection.
A New Potent Angiogenesis Inhibitor, FR-118487
TAKANAO, OTSUKA,OHKAWA, TAKEHIKO,SHIBATA, TOSHIHIRO,OKU, TERUO,OKUHARA, MASAKUNI,TERANO, HIROSHI,MASANOBU KOHSAKA,IMANAKA, HIROSHI 한국미생물 · 생명공학회 1991 Journal of microbiology and biotechnology Vol.1 No.3
A new angiogenesis inhibitor, FR-118487 was obtained by chemical modification of FR-111142 which was isolated from the fermentation products of Scolecobasidium arenarium F-2015. The antiangiogenic activity of FR-118487 was compared with that of the parent compound, FR-111142. In the endothelial cell proliferation test in vitro and the anglogenesis in the chick embryo chorioallantoic membrane assay, FR-118487 had about 5∼10 times stronger antiangiogenic activities than FR-111142. In addition, FR-118487 inhibited the angiogenesis in the rabbit corneal assay and suppressed the solid tumor growth in mice. These findings showed that FR-118487 would be a unique antiangiogenic agent with promising antitumor activity.