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      • KCI등재

        Collegiate female athletes’ body image and clothing behaviors

        Mary Claire Nemeth,Huiju Park,Jane Mendle 한국의류학회 2020 Fashion and Textiles Vol.7 No.1

        This study investigated the body image experiences unique to collegiate female athletes in relation to their apparel wear. Female athletes (n = 36) participated in interview sessions, 3D body scanning, and photography of garment fit, and the Multidimensional Body-Self Relations Questionnaire (MBSRQ). Through Qualtrics, the MBSRQ was distributed to female college students nationwide, to obtain a larger participant pool (Lean sport athletes (n = 36), non-lean sport athletes (n = 42) and non-athletes (n = 101). Results indicated that both sports groups were most influenced by sport specific body ideals. Correlation of body image and athletic uniforms was more influenced by the fit of the uniform than by the categorization of the sport. Both lean and non-lean sport group participants expressed dissatisfaction in pant fit. 3D body scans revealed similar body proportions and shape between sports groups. MBSRQ results indicated no significant difference between sports groups but higher body image scores in comparison to non-athletes.

      • KCI등재

        Asthma and the Risk of Rheumatoid Arthritis: An Insight into the Heterogeneity and Phenotypes of Asthma

        ( Mary Claire Rolfes ),( Young Jun Juhn ),( Chung-il Wi ),( Youn Ho Sheen ) 대한결핵 및 호흡기학회 2017 Tuberculosis and Respiratory Diseases Vol.80 No.2

        Asthma is traditionally regarded as a chronic airway disease, and recent literature proves its heterogeneity, based on distinctive clusters or phenotypes of asthma. In defining such asthma clusters, the nature of comorbidity among patients with asthma is poorly understood, by assuming no causal relationship between asthma and other comorbid conditions, including both communicable and noncommunicable diseases. However, emerging evidence suggests that the status of asthma significantly affects the increased susceptibility of the patient to both communicable and noncommunicable diseases. Specifically, the impact of asthma on susceptibility to noncommunicable diseases such as chronic systemic inflammatory diseases (e.g., rheumatoid arthritis), may provide an important insight into asthma as a disease with systemic inflammatory features, a conceptual understanding between asthma and asthma-related comorbidity, and the potential implications on the therapeutic and preventive interventions for patients with asthma. This review discusses the currently under-recognized clinical and immunological phenotypes of asthma; specifically, a higher risk of developing a systemic inflammatory disease such as rheumatoid arthritis and their implications, on the conceptual understanding and management of asthma. Our discussion is divided into three parts: literature summary on the relationship between asthma and the risk of rheumatoid arthritis; potential mechanisms underlying the association; and implications on asthma management and research.

      • KCI등재

        Anterior Shoulder Instability with Concomitant Superior Labrum from Anterior to Posterior (SLAP) Lesion Compared to Anterior Instability without SLAP Lesion

        Claire Marie C. Durban,Je Kyun Kim,김세훈,Joo Han Oh 대한정형외과학회 2016 Clinics in Orthopedic Surgery Vol.8 No.2

        Background: The aims of this study were to investigate the clinical characteristics of patients with combined anterior instability and superior labrum from anterior to posterior (SLAP) lesions, and to analyze the effect of concomitant SLAP repair on surgical outcomes. Methods: We retrospectively reviewed patients who underwent arthroscopic stabilization for anterior shoulder instability between January 2004 and March 2013. A total of 120 patients were available for at least 1-year follow-up. Forty-four patients with reparable concomitant detached SLAP lesions (group I) underwent combined SLAP and anterior stabilization, and 76 patients without SLAP lesions (group II) underwent anterior stabilization alone. Patient characteristics, preoperative and postoperative pain scores, Rowe scores, and shoulder ranges of motion were compared between the 2 groups. Results: Patients in group I had higher incidences of high-energy trauma (p = 0.03), worse preoperative pain visual analogue scale (VAS) (p = 0.02), and Rowe scores (p = 0.04). The postoperative pain VAS and Rowe scores improved equally in both groups without significant differences. Limitation in postoperative range of motion was similar between the groups (all p-value > 0.05). Conclusions: Anterior instability with SLAP lesion may not be related to frequent episodes of dislocation but rather to a highenergy trauma. SLAP fixation with anterior stabilization procedures did not lead to poor functional outcomes if appropriate surgical techniques were followed.

      • SCOPUSKCI등재

        Asthma and the Risk of Rheumatoid Arthritis: An Insight into the Heterogeneity and Phenotypes of Asthma

        Rolfes, Mary Claire,Juhn, Young Jun,Wi, Chung-Il,Sheen, Youn Ho The Korean Academy of Tuberculosis and Respiratory 2017 Tuberculosis and Respiratory Diseases Vol.80 No.2

        Asthma is traditionally regarded as a chronic airway disease, and recent literature proves its heterogeneity, based on distinctive clusters or phenotypes of asthma. In defining such asthma clusters, the nature of comorbidity among patients with asthma is poorly understood, by assuming no causal relationship between asthma and other comorbid conditions, including both communicable and noncommunicable diseases. However, emerging evidence suggests that the status of asthma significantly affects the increased susceptibility of the patient to both communicable and noncommunicable diseases. Specifically, the impact of asthma on susceptibility to noncommunicable diseases such as chronic systemic inflammatory diseases (e.g., rheumatoid arthritis), may provide an important insight into asthma as a disease with systemic inflammatory features, a conceptual understanding between asthma and asthma-related comorbidity, and the potential implications on the therapeutic and preventive interventions for patients with asthma. This review discusses the currently under-recognized clinical and immunological phenotypes of asthma; specifically, a higher risk of developing a systemic inflammatory disease such as rheumatoid arthritis and their implications, on the conceptual understanding and management of asthma. Our discussion is divided into three parts: literature summary on the relationship between asthma and the risk of rheumatoid arthritis; potential mechanisms underlying the association; and implications on asthma management and research.

      • POTENTIAL BIODIESEL FUEL FROM STERCULIA FOETIDA WITH ZERO WASTE SYSTEM

        Dave Albert Patrimonio,Ana Marie Piodos,Dessere Claire Saragena 국제과학영재학회 2014 APEC Youth Scientist Journal Vol.6 No.1

        In order to cope with the huge demand for tomato in various industries, its production has to be optimized using novel approaches. Heavy metals present in soil such as arsenic can potentially affect its growth and quality, and may induce oxidative stress on it by producing free radicals that damage its cells. In this study, the effect of arsenic on the leaves of Solanum lycopersicum was quantified in terms of hydrogen peroxide, which is directly involved in the degradation of eukaryotic cells when there is oxidative stress. Tomato seeds grown in an ambient temperature of approximately 29°C were exposed to 5 pM arsenic trioxide for 7 days before shoot length was measured and leaves were tested for hydrogen peroxide content spectrophotometrically. Results showed that As-treated plants reached an average height of 9.92 em while control plants reached 11.03 em. Hydrogen peroxide in the leaves is found to be relatively higher on the arsenic-treated plants than on control plants. The former was found to have an H202 concentration of0.257 pM, compared to the 0.15 pM ofthe control. This difference in hydrogen peroxide relates to a 0. 008 p -value in ANOVA and shows that it is significant. Plant physiology may be impeded when exposed to high concentrations of this metal. It is concluded that arsenic contamination inhibits plant growth and induces oxidative stress in the leaf tissue of tomato plants.

      • SCISCIESCOPUS

        Mutations in KEOPS-complex genes cause nephrotic syndrome with primary microcephaly

        Braun, Daniela A,Rao, Jia,Mollet, Geraldine,Schapiro, David,Daugeron, Marie-Claire,Tan, Weizhen,Gribouval, Olivier,Boyer, Olivia,Revy, Patrick,Jobst-Schwan, Tilman,Schmidt, Johanna Magdalena,Lawson, J Nature Pub. Co 2017 Nature genetics Vol.49 No.10

        <P>Galloway-Mowat syndrome (GAMOS) is an autosomal-recessive disease characterized by the combination of early-onset nephrotic syndrome (SRNS) and microcephaly with brain anomalies. Here we identified recessive mutations in OSGEP, TP53RK, TPRKB, and LAGE3, genes encoding the four subunits of the KEOPS complex, in 37 individuals from 32 families with GAMOS. CRISPR-Cas9 knockout in zebrafish and mice recapitulated the human phenotype of primary microcephaly and resulted in early lethality. Knockdown of OSGEP, TP53RK, or TPRKB inhibited cell proliferation, which human mutations did not rescue. Furthermore, knockdown of these genes impaired protein translation, caused endoplasmic reticulum stress, activated DNA-damage-response signaling, and ultimately induced apoptosis. Knockdown of OSGEP or TP53RK induced defects in the actin cytoskeleton and decreased the migration rate of human podocytes, an established intermediate phenotype of SRNS. We thus identified four new monogenic causes of GAMOS, describe a link between KEOPS function and human disease, and delineate potential pathogenic mechanisms.</P>

      • KCI등재

        Comparative Performance of the Reverse Algorithm Using Architect Syphilis TP Versus the Traditional Algorithm Using Rapid Plasma Reagin in Florida’s Public Health Testing Population

        Yolanda R. Totten,Bonnie M. Hardy,Berry Bennett,Marie-Claire Rowlinson,,Susanne Crowe, 대한진단검사의학회 2019 Annals of Laboratory Medicine Vol.39 No.4

        In Florida, where syphilis is a reportable disease, the number of primary and secondary (P&S) syphilis cases has increased from 3,266 in 2008–2010 to 5,340 in 2013–2015, a 63% increase. The objective of this study was to compare the performance and sensitivity of the syphilis reverse algorithm with the traditional algorithm for detecting P&S (infectious) syphilis cases. Clinical specimens from individuals who self-referred for syphilis testing at public health clinics were processed using the traditional algorithm (non-treponemal rapid plasma reagin (RPR) test followed by a confirmatory treponemal (EIA) test) and then further tested with the Architect Syphilis TP (ASTP) immunoassay (Abbott Diagnostics, Chicago, IL, USA) or by RPR confirmation, if needed (reverse algorithm). Of 1,079 specimens, 59 were positive for syphilis. The sensitivity of the reverse algorithm was 98.3% (58/59) and of the traditional algorithm was 72.9% (43/59). Based on clinical evidence, of the 16 traditional algorithm-negative but reverse algorithm-positive cases, 68.8% (11/16) were classified as missed P&S infections (treatment naïve) and 31.2% (5/16) were classified as missed past syphilis (latent or infections with documented linkage to care). The reverse algorithm enables the detection of additional P&S syphilis cases missed by our current traditional algorithm.

      • SCISCIESCOPUS

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