Relationship Between Psychological Factors and Pain Intensity in Temporomandibular Disorders with or without Central Sensitization: A Cross-Sectional Observational Study Using Multiple Regression Analysis

Pérez Sebastián Eustaquio Martín,Pérez Sebastián Eustaquio Martín,Córdova José Andrés Díaz,Cortés Leidy Milena Posada 대한안면통증∙구강내과학회 2023 Journal of Oral Medicine and Pain Vol.48 No.3

Purpose: To quantify the relationship between perceived pain intensity and psychological variables in a sample of participants with temporomandibular disorder, with or without central sensitization (CS). Methods: A cross-sectional study with nonprobability convenience sampling was conducted from January 1, 2022, to June 30, 2023. Pain intensity (Numeric Pain Rating Scale), anxiety (State-Trait Anxiety Questionnaire, STAI), catastrophizing (Pain Catastrophizing Scale, PCS), perceived stress (Perceived Stress Scale, PSS), and sleep quality (Pittsburgh Sleep Quality Index, PSQI) were assessed. Statistical analysis was performed using IBM SPSS Statistics for Windows, Version 20.0 (IBM Co.), which included descriptive and normality analyses and the calculation of strength of multiple correlational regression. Results: A total of 52 (n=34 female 65.4%; n=18 male 34.6%) subjects with diagnosis of temporomandibular disorders (TMD) were finally included. A total of 26 participants (n=26, 50.0%) were cases suffered from CS (TMD-CS mean=46.62±11.24) while the remaining participants (n=26, 50.0%) were the controls (TMD-nCS mean=26.77, standard deviation [SD]=8.42). The pain intensity was moderate in both groups TMDCS (mean=7.62, SD=0.83) and TMD-nCS (mean=7.05, SD=0.86), anxiety (TMD-CS STAI mean=53.27, SD=11.54; TMD-nCS STAI mean=49, SD=11.55), catastrophizing (TMD-CS PCS mean=46.27, SD=9.75; TMD-nCS PCS mean=26.69, SD=4.97), perceived stress (TMDCS PSS mean=30.35, SD=4.91; TMD-nCS PSS mean=26.12, SD=6.60) and sleep quality (TMD-CS PSQI mean=15.81, SD=3.65; TMD-nCS PSQI mean=12.77, SD=2.76) levels were measured in both groups. In TMD-CS and TMD-nCS, higher anxiety levels were moderately and significantly associated with greater pain intensity β=0.4467 (t=2.477, p=0.021) and β=0.5087 (t=2.672, p=0.014). Nevertheless, catastrophizing, perceived stress and sleep quality were not associated to pain intensity in neither of group. Conclusions: In both TMD-CS and TMD-nCS patients, elevated anxiety levels were moderately and significantly associated with increased pain intensity. However, heightened levels of pain catastrophizing, perceived stress, and poor sleep quality were not significantly associated with increased pain intensity in either of the two analyzed groups.

Slide Session : OS-HEM-03 ; Hematology : Hemophagocytic Syndrome in Internal Medicine: Iden-tification of Infectious Triggers, Therapeutic Manage-ment and Mortality in 88 Patients (REGHEM-GEAS-SEMI)

( Pilar BRITO ZERÓN ),( Marta PEREZ DE LIS NOVO ),( Roberto PÉREZ ALVAREZ ),( Pedro MORAL MORAL ),( Aleida MARTÍNEZ ZAPICO ),( Guadalupe FRAILE ),( Eva FONSECA ),( María VAQUERO HERRERO ),( Angela RUI 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

Background: To analyze the therapeutic management and the main epidemiological and clinical characteristics related to survival in a large series of patients with hemophagocytic syndrome (HS) diagnosed in Departments of Internal Medicine. Methods: In June 2013, the Study Group of Autoimmune Diseases (GEAS-SEMI) creates a national registry of patients with HS. Patients were diagnosed according to the fulfillment of the criteria of the Histiocytosis Society in 1991 and updated in 2004. Results: At June 15, 2014, the REGHEM registry included 88 patients with HS, 35 (40%) men and 55 (60%) women, with a mean age at diagnosis of 49.16 years (range 12- 84 years). During the admission that led to the diagnosis of SH, acute infections were identified in 50 (57%) patients, including viruses (n=20), bacteria (n=13), mycobacteria (n=8) and parasites/fungi (n=13). Patients were treated with corticosteroids (n=40), etoposide (n=12), cyclosporin A (n=12), methotrexate (n=4), tacrolimus (n=2) rituximab (n=3), intravenous immunoglobulins (n=2) and chemotherapy (n=5). A total of 44 (50%) patients died. The main factors associated with mortality were analytical parameters at diagnosis such as the presence of severe anemia (Hb <9 g/L, 89% vs 66%, p=0.01), platelet count <100,000/mm3 (96% vs 64%, p<0.001), neutropenia <1000/mm3 (59% vs 39%, p=0.044), and bacterial infections as precipitating agent (77% vs 45%, p=0.034); a clinical presentation including lymphadenopathy was associated with a lower mortality (59% vs 39%, p=0.044). Conclusions: Hemophagocytic syndrome is a severe multisystemic disease associated in nearly 50% of cases with an acute infection, and usually requires vital support in intensive care units. Despite this and the use of a complex therapeutic approach, half of the patients died. The main prognostic factor identified is the presence at diagnosis of severe cytopenias and the coexistence of bacterial infections.

Molecular Identification of Adenocephalus pacificus (Cestoda) from Three Human Cases in Lima Province, Peru

Aarón Mondragón-Martínez,Rosa Martínez-Rojas,Enrique Garcia-Candela,Abraham Delgado-Escalante,Manuel Tantaleán-Vidaurre,Lidia Cruz-Neyra 대한기생충학ㆍ열대의학회 2020 The Korean Journal of Parasitology Vol.58 No.4

The Pacific tapeworm Adenocephalus pacifcus (syn. Diphyllobothrium pacificum) is a causative agent of diphyllobothriosis occurred in Pacific coast of South America, mainly in Peru. Source of infections are traditional meal from raw or undercooked marine fish such as “cebiche”. We confirmed 3 new cases, one including scolex and the other two headless. A strobila 46 cm long without scolex was discharged from an 8-year-old boy before treatment. Specimens were confirmed morphologically by presence of tegumental protuberances on proglottids and small sized eggs. Partial sequence of cytochrome c oxidase subunit 1 gene was congruent with A. pacificus sequences.

La noción de precursores en los discursos narrativos a partir de las obras “Japonesas” de Mario Bellatin

Álvaro Martín Navarro 서울대학교 라틴아메리카연구소 2010 이베로아메리카硏究 Vol.21 No.2

El presente ensayo es una propuesta acerca de la homogeneidad de la escritura, a partir de las reflexiones de Jorge Luis Borges que se halla en su obra Kafka y sus precursores. Proponemos la idea de que en cada escritor hay matices y estilos de otros escritores que llegan de forma directa, por medio de sus lecturas, o precursores directos; pero también de forma indirecta, donde los métodos, estéticas y reflexiones, están presentes en diversas obras de esos autores precedentes y en los autores influenciados sin que necesariamente exista una relación causa efecto, por lo que a veces “parecieran” que diversas obras literarias están escritas por la misma mano sin circunscribirse a un espacio o tiempo determinado. Por lo que tenemos dos niveles de precursores, los propios del autor, los leídos, y los propios del sujeto literario, determinado por propuestas culturales, míticas e ideológicas. Tomamos al autor mexicano Mario Bellatin y nos proponemos a presentar estas ideas en una serie de análisis que nacen de sus obras desarrolladas en (su) Japón: Shiki Nagaoka, El jardín de la señora Murakami, Bola negra;paralelamente estableceremos vasos comunicantes entre las obras de Bellatin con algunas obras literarias japoneses, mostrando la idea de precursor en la estructura narrativa del autor por una parte, y del sujeto literario por otra.

Multistep electron transfer systems based on silicon phthalocyanine, [60]fullerene and trinitrofluorenone

Martí,n-Gomis, Luis,Ohkubo, Kei,Ferná,ndez-Lá,zaro, Fernando,Fukuzumi, Shunichi,Sastre-Santos, Á,ngela Royal Society of Chemistry 2010 Chemical communications Vol.46 No.22

<P>The synthesis and photodynamics in the absence and in the presence of Mg<SUP>2+</SUP> ions of a novel TNF-C<SUB>60</SUB>-SiPc-C<SUB>60</SUB>-TNF pentad are reported. The redox gradient approach allows to obtain a long-lived CS state of 160 ns and 200 μs in the absence and in the presence of Mg<SUP>2+</SUP> ions, respectively.</P> <P>Graphic Abstract</P><P>The redox gradient approach in a TNF-C<SUB>60</SUB>-SiPc-C<SUB>60</SUB>-TNF pentad allows the generation of a long-lived CS state of 160 ns/200 μs in the absence/presence of Mg<SUP>2+</SUP> ions respectively. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c002077j'> </P>

Removal of textile dyes in wastewater using polyelectrolytes containing tetrazole groups

Martín Caldera-Vil,Alejandra-Alicia Peláez-Cid,Miriam-Amelia Martins-Alho,Ana-María Herrera-González 한국화학공학회 2018 Korean Journal of Chemical Engineering Vol.35 No.12

Textile dyes are some of the pollutants which have received the most attention because of the large volume of wastewater generated by the textile industry. Removal by means of adsorption is one of the most versatile alternatives to treat these effluents. Even though different adsorbents such as activated carbons and mineral materials have been proposed, polymeric adsorbents are a viable alternative. This work reports for the first time the use of polyelectrolyte PTZ and macroelectrolyte MTZ containing tetrazole groups as adsorbents useful in the textile dyes removal present in aqueous solutions and wastewater. Because of the anionic character of the tetrazole group, MTZ exhibits selective adsorption capabilities for cationic dyes of up to 156.25mg·g1. The kinetic study of the process of adsorption shows that PTZ and MTZ fit a pseudo second-order model. MTZ also shows utility as a flocculant agent in the treatment of wastewater containing dyes Indigo Blue and Reactive Black. The results showed that PTZ and MTZ may be used in the treatment of wastewater in a process of coagulation-flocculation followed by the treatment by adsorption. This twostage treatment removed up to 95% of the dye present in the wastewater. As well as removing the dyes, the values for COD, suspended solids, pH, and color of the wastewater decreased, thus significantly improving its quality.

Nonlinear dynamic analysis of a RC bridge subjected to seismic loading

Germán Nanclares,Daniel Ambrosini,Oscar Curadelli,Martín Domizio 국제구조공학회 2020 Smart Structures and Systems, An International Jou Vol.26 No.6

Collapse of bridges in recent earthquakes demonstrates the need to deepen the understanding of the behaviour of these structures against seismic actions. This paper presents a highly detailed numerical model of an actual bridge subjected to extreme seismic action which results in its collapse. Normally, nonlinear numerical models have high difficulties to achieve convergence when reinforced concrete is intended to be represented. The main objective of this work is to determine the efficiency of different passive control strategies to prevent the structural collapse of an existing bridge. Metallic dampers and seismic isolation by decoupling the mass were evaluated. The response is evaluated not only in terms of reduction of displacements, but also in increasing of shear force and axial force in key elements, which can be a negative characteristic of the systems studied. It can be concluded that the use of a metallic damper significantly reduces the horizontal displacements and ensures the integrity of the structure from extreme seismic actions. Moreover, the isolation of the deck, which in principle seems to be the most effective solution to protect existing bridges, proves inadequate for the case analysed due to its dynamic characteristics and its particular geometry and an unpredictable type of axial pounding in the columns. This unexpected effect on the isolation system would have been impossible to identify with simplified models.

Subclinical versus advanced forms of alcohol-related liver disease: Need for early detection

Concepción Gómez-Medina,Luma Melo,David Martí-Aguado,Ramón Bataller 대한간학회 2023 Clinical and Molecular Hepatology(대한간학회지) Vol.29 No.1

Alcohol-related liver disease (ALD) consists of a wide spectrum of clinical manifestations and pathological features, ranging from asymptomatic patients to decompensated cirrhosis and hepatocellular carcinoma. Patients with heavy alcohol intake and advanced fibrosis often develop a subacute form of liver failure called alcohol-induced hepatitis (AH). Globally, most patients with ALD are identified at late stages of the disease, limiting therapeutic interventions. Thus, there is a need for early detection of ALD patients, which is lacking in most countries. The identification of alcohol misuse is hampered by the existence of alcohol underreporting by many patients. There are useful biomarkers that can detect recent alcohol use. Moreover, there are several non-invasive techniques to assess the presence of advanced fibrosis among patients with alcohol misuse, which could identify patients at high risk of liver related events or early death. In this review, we discuss differences between early stages of ALD and AH as the cornerstone of advanced forms. A global overview of epidemiological, anthropometric, clinical, analytical, histological, and molecular differences is summarized in this article. We propose that campaigns aimed at identifying patients with subclinical forms can prevent the development of life-threatening forms.

A 1-Year Cost Analysis of Spinal Surgical Procedures in Spain: Neurosurgeons Versus Orthopedic Surgeons

Martín Avellanal,Mónica Martin-Corvillo,Laura Barrigon,Manuel Vazquez Espi,Clara M. Esteban Escolar 대한척추신경외과학회 2019 Neurospine Vol.16 No.2

Objective: To evaluate the direct costs of various spinal surgical procedures within 1 year of follow-up and to compare the profiles of neurosurgeons and orthopedic surgeons. Methods: All spinal procedures performed within a 10-month period in patients covered by a private insurance company were included. Costs related to the spinal interventions were systematically registered in the company database. Associated costs during the 1-year follow-up were recorded. Results: In total, 1,862 patients were included, with a total cost of €11,050,970, of whom 34.8% underwent noninstrumented lumbar decompression (€3,473), 27.1% dorsolumbar instrumented fusion (€6,619), 14.6% nucleoplasty (€1,323), 13.5% cervical surgery (€4,463), 3.4% kyphoplasty (€4,200), 2.9% scoliosis (€15,414), 1.2% oncologic surgery (€5,590), 0.5% traumatic compression (€7,844), and 4.7% (€1,343) other minor interventions (mainly rhizotomies). Approximately 42% of patients required reinterventions within the first year, with a global extra cost of €7,280,073; 11% were referred to the pain clinic, with a €114,663 cost; 55.5% were men; and the most common age range of patients who received an intervention was 65–75 years. Neurosurgeons performed 60% of all interventions. Noninstrumented lumbar operations were performed by neurosurgeons twice as often as instrumented operations, and they performed 76% of cervical operations. Orthopedic surgeons performed 2.5 times more instrumented than noninstrumented lumbar operations, and almost all scoliosis and rhizotomy procedures. Conclusion: The direct costs of spinal surgery in Spain were generally lower than those reported in other European Union countries and the United States. Neurosurgeons and orthopedic surgeons had different spine surgical profiles and costs.

Multi-dimensional coincidence point theorems for weakly compatible mappings with the C L R g -property in (fuzzy) metric spaces

Martí,nez-Moreno, J,Roldá,n, A,Roldá,n, C,Cho, Yeol Je Springer (Biomed Central Ltd.) 2015 Fixed point theory and applications Vol.2015 No.1