Prosthodontic rehabilitation of a patient with bilateral auricular deformity

Sneha Shivkumar Mantri,Ram U. Thombre,Daigavane Pallavi 대한치과보철학회 2011 The Journal of Advanced Prosthodontics Vol.3 No.2

Maxillofacial prosthodontics is an art and science which provides life like appearance to the person with facial deformity. Maxillofacial prosthetic rehabilitation for acquired defects has become more complex and sophisticated with advancement in techniques and materials. This case report describes the clinical and laboratory procedure for fabricating an auricular prosthesis for a patient with trauma related bilateral auricular deformity. Ear prosthesis was fabricated in two parts taking retention from external auditory canal.

Invasion potential of Kappaphycus alvarezii on corals at Kurusadai Island, Gulf of Mannar, India

Mandal, Subir Kumar,Mantri, Vaibhav A.,Haldar, Soumya,Eswaran, Karuppanan,Ganesan, Meenakshisundaram The Korean Society of Phycology 2010 ALGAE Vol.25 No.4

The marine red alga Kappaphycus alvarezii is a major source of $\kappa$-carrageenan. It has been introduced in 20 countries including India. Recently, several reports have expressed concerns about Kappaphycus invasion on Acropora corals at Kurusadai Island in the Gulf of Mannar, India, which is part of a marine bioreserve. To understand the extent of the Kappaphycus invasion, 27 randomly selected locations around Kurusadai Island and the mainland coast were surveyed during May-August 2008 and July 2009. Our rigorous sampling revealed that K. alvarezii was confined to two different patches of 105 m $\times$ 55 m and 8 m $\times$ 9 m located at the southeastern part of Kurusadai Island. The actual extent of the K. alvarezii canopy coverage was 76.7 $m^2$, accounting for less than 0.0035% of the total coral reef area. The daily growth rate of the K. alvarezii at Kurusadai was 0.7%. K. alvarezii was not observed in the coral reef area of the adjoining Pullivasal and Poomarichan Islands or the Palk Bay area cultivation sites. The lack of functional reproductive cycle, low spore viability, and the absence of microscopic phases in the life cycle of this alga coupled with the abundance presence of herbivores may restrict the further spread of this alga, so its invasive potential at Kurusadai Island is considered remote.

Establishing postprandial bio-equivalency and IVIVC for generic metformin sustained release small sized tablets

Chandramohan Eaga,Shivakumar Mantri,Rajkumar Malayandi,Phani Krishna Kondamudi,Sumon Chakraborty,S. V. N. Raju,Deepika Aggarwal 한국약제학회 2014 Journal of Pharmaceutical Investigation Vol.44 No.3

The objective of current study was to developmetformin hydrochloride modified release small sizedtablets, and to evaluate its bioequivalence when comparedwith the reference product (Glucophage SR). The physicochemicalproperties of the formulated and referencetablets were determined and compared. The in vitro dissolutionprofiles of formulated tablets were obtained usingbio-relevant media and IVIVC was established. Bioequivalenceinvestigation was carried out in 32 healthy malevolunteers who received a single dose 1,000 mg of bothtest and reference products in a randomized two-waycrossover design in postprandial conditions. After dosing,serial blood samples were collected for a period of 48 h. Metformin concentration was assayed by using a validatedLC–MS/MS method. The log-transformed Cmax and AUCwere statistically compared by analysis of variance, and the 90 % confidence intervals (CI) of the ratio of the logtransformedCmax and AUC between the most promisingdeveloped formulation and the reference product weredetermined. It was deduced that the dissolution rate profileof the formulated modified release small sized tablets wassimilar to the reference product employed in the study. Their similarity and difference factors were found to bewell within the established limits. In the bioequivalencestudy, the difference in Cmax, AUClast and AUCinf betweenthe test and reference product was not statistically significant,with the 90 % CI of 100.73–116.20, 86.16–97.37 and87.12–96.99 %, respectively. The results suggested that themetformin small tablets formulated with reduced quantityof controlled release polymer were found to be bioequivalentin the postprandial state. For these small tablets,pH 5.5 acetate buffer as a bio-relevant dissolution mediafor the development of IVIVC.

Invasion potential of Kappaphycus alvarezii on corals at Kurusadai Island, Gulf of Mannar, India

Subir Kumar Mandal,Vaibhav A. Mantri,Soumya Haldar,Karuppanan Eswaran,Meenakshisundaram Ganesan 한국조류학회I 2010 ALGAE Vol.25 No.4

The marine red alga Kappaphycus alvarezii is a major source of κ-carrageenan. It has been introduced in 20 countries including India. Recently, several reports have expressed concerns about Kappaphycus invasion on Acropora corals at Kurusadai Island in the Gulf of Mannar, India, which is part of a marine bioreserve. To understand the extent of the Kappaphycus invasion, 27 randomly selected locations around Kurusadai Island and the mainland coast were surveyed during May-August 2008 and July 2009. Our rigorous sampling revealed that K. alvarezii was confined to two different patches of 105 m × 55 m and 8 m × 9 m located at the southeastern part of Kurusadai Island. The actual extent of the K. alvarezii canopy coverage was 76.7 m2, accounting for less than 0.0035% of the total coral reef area. The daily growth rate of the K. alvarezii at Kurusadai was 0.7%. K. alvarezii was not observed in the coral reef area of the adjoining Pullivasal and Poomarichan Islands or the Palk Bay area cultivation sites. The lack of functional reproductive cycle, low spore viability,and the absence of microscopic phases in the life cycle of this alga coupled with the abundance presence of herbivores may restrict the further spread of this alga, so its invasive potential at Kurusadai Island is considered remote.

Effect of agglomerated zirconia-toughened mullite on the mechanical properties of giant cane fiber mat epoxy laminated composites

Pruthwiraj Sahu,Sambit Kumar Parida,Sisir Mantry 국제구조공학회 2019 Structural Engineering and Mechanics, An Int'l Jou Vol.70 No.2

This paper depicts the development and characterizations of laminated composites made with cellulosic giant cane (Arundinaria gigantea) fiber mats and epoxy resin. Zirconia-toughened mullite (ZTM) is used as a filler material in the laminated composite which was prepared from sillimanite through plasma processing technique. The mechanical characterizations of this composite have been carried out as per ASTM standards to evaluate its usability as a structural material. The effects of varying weight percentages of the filler and two different fiber orientations namely, angle-ply [+45°/-45°/+45°] and balanced cross-ply [0°/90°/0°] on the physical and mechanical properties such as density, microhardness, impact strength, tensile strength and interlaminar shear strength of the layered composite specimens have been investigated. The study indicates that the inclusion of zirconia-toughened mullite in the composite laminate as filler improves its mechanical properties. Moreover, the use of giant cane fiber mat in the laminate is more eco-friendly than the synthetic fibers. This research also helps in generating additional data to enrich the repository of natural fiber reinforced laminated composites.

Thyroid Abscess After Fine Needle Aspiration with Spontaneous Rupture into the Trachea : A Case Report

Sanjay Marwah,Shouvik Das,Abhishek Mandal,Ritesh Kumar,Sandeep Chauhan,Krishna Rekha Mantry,Sandeep Kumar Malik 대한외상중환자외과학회 2023 Journal of Acute Care Surgery Vol.13 No.2

Fine needle aspiration (FNA) of the thyroid is a well-tolerated minimally invasive procedure. Thyroid abscess, as a complication of FNA in an immune-competent adult, is extremely rare. Diagnosis requires a high index of suspicion, for which treatment is intravenous antibiotics, drainage, and sometimes surgery. Here we present a case of thyroid abscess in an otherwise healthy man who presented with neck pain, rapidly increasing neck swelling, difficulty in swallowing, and hoarseness of the voice that developed two weeks after diagnostic FNA of a thyroid nodule which had been present for ten months. Despite antibiotic treatment, the abscess ruptured into the trachea, requiring surgical intervention. This highlights the importance of maintaining asepsis during FNA of the thyroid. Timely diagnosis of a thyroid abscess is essential to avoid life-threatening airway complications.