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Multi‐site evaluation of hydrology component of SWAT in the coastal plain of southwest Georgia
Cho, Jaepil,Bosch, David,Vellidis, George,Lowrance, Richard,Strickland, Timothy John Wiley Sons, Ltd 2013 Hydrological processes Vol.27 No.12
<P><B>Abstract</B></P><P>Simulation of watershed scale hydrologic and water quality processes is important for watershed assessments. Proper characterization of the accuracy of these simulations, particularly in cases with limited observed data, is critical. The Soil & Water Assessment Tool (SWAT) is frequently used for watershed scale simulation. The accuracy of the model was assessed by extrapolating calibration results from a well studied Coastal Plain watershed in Southwest Georgia, USA, to watersheds within the same geographic region without further calibration. SWAT was calibrated and validated on a 16.7‐km<SUP>2</SUP> subwatershed within the Little River Experimental Watershed by varying six model parameters. The optimized parameter set was then applied to a watershed of similar land use and soils, a smaller watershed with different land use and soils and three larger watersheds within the same drainage system without further calibration. Simulation results with percent bias (PB) ±15% ≤ PB < ±25% and Nash–Sutcliffe efficiency (NSE) 0.50 < NSE ≤ 0.65 were considered to be satisfactory, whereas those with PB < ±10% and 0.75 < NSE ≤ 1.00 were considered very good. With these criteria, simulation results for the five non‐calibration watersheds were satisfactory to very good. Differences across watersheds were attributed to differences in soils, land use, and surficial aquifer characteristics. These results indicate that SWAT can be a useful tool for predicting streamflow for ungauged watersheds with similar physical characteristics to the calibration watershed studied here and provide an indication of the accuracy of hydrologic simulations for ungauged watersheds. Copyright © 2012 John Wiley & Sons, Ltd.</P>
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Jessica J. Matchynski,Steven A. Lowrance,Colleen Pappas,Julien Rossignol,Nicole Puckett,Michael Sandstrom,Gary L. Dunbar 한국식품영양과학회 2013 Journal of medicinal food Vol.16 No.4
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that affects more than five million Americans and is characterized by a progressive loss of memory, loss of cholinergic neurons in the basal forebrain, formation of amyloid plaques and neurofibrillary tangles, and an increase in oxidative stress. Recent studies indicate that dietary supplements of antioxidants and omega-3 and omega-6 fatty acids may reduce the cognitive deficits in AD patients. The current study tested a combinatorial treatment of antioxidants from tart cherry extract and essential fatty acids from Nordic fish and emu oils for reducing cognitive deficits in the mu-p75 saporin (SAP)–induced mouse model of AD. Mice were given daily gavage treatments of Cerise® Total-Body-Rhythm™ (TBR; containing tart cherry extract, Nordic fish oil, and refined emu oil) or vehicle (methylcellulose) for 2 weeks before intracerebroventricular injections of the cholinergic toxin, mu-p75 SAP, or phosphate-buffered saline. The TBR treatments continued for an additional 17 days, when the mice were tested on a battery of cognitive and motor tasks. Results indicate that TBR decreased the SAP-induced cognitive deficits assessed by the object-recognition, place-recognition, and Morris-water-maze tasks. Histological examination of the brain tissue indicated that TBR protected against SAP-induced inflammatory response and loss of cholinergic neurons in the area around the medial septum. These findings indicate that TBR has the potential to serve as an adjunctive treatment which may help reduce the severity of cognitive deficits in disorders involving cholinergic deficits, such as AD.
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