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      • KCI등재

        The reverse model of repositioning: A case study of the Howard Johnson hotel chain in China

        Lianping Ren,Po-Ju Chen,Jinlin Zhao,Peilai Wang 한국마케팅과학회 2017 마케팅과학연구 Vol.27 No.4

        This study explores the repositioning of an international hotel brand, Howard Johnson China (HoJo China) and examines the decoding strategies and process the fi rm undertook to establish itself in that market. The study reports that HoJo China had gone through a reverse model of repositioning, starting with the repositioning decision, followed by customer response analysis, and competitor analysis. A persistent pursuit of service quality and eff ective management consolidated the repositioning of HoJo China. The study includes creating a causal map to analyze the success factors of the repositioning case of HoJo China. The discussion describes the infl uences of contextual factors.

      • KCI등재

        Microstructural Abnormalities of Basal Ganglia and Thalamus in Bipolar and Unipolar Disorders: A Diffusion Kurtosis and Perfusion Imaging Study

        Lianping Zhao,Ying Wang,Yanbin Jia,Shuming Zhong,Yao Sun,Zhifeng Zhou,Zhongping Zhang,Li Huang 대한신경정신의학회 2017 PSYCHIATRY INVESTIGATION Vol.14 No.4

        Objective: Bipolar disorder (BD) is often misdiagnosed as unipolar depression (UD), leading to mistreatment and poor clinical outcomes. However, little is known about the similarities and differences in subcorticalgray matter regions between BD and UD. Methods: Thirty-five BD patients, 30 UD patients and 40 healthy controls underwent diffusional kurtosis imaging (DKI) and three dimensional arterial spin labeling (3D ASL). The parameters including mean kurtosis (MK), axial kurtosis (Ka), radial kurtosis (Kr), fractional anisotropy (FA), mean diffusivity (MD), axial diffusivity (Da), radial diffusivity (Dr) and cerebral blood flow (CBF) were measured by using regions-of-interest analysis in the caudate, putamen and thalamus of the subcortical gray matter regions. Results: UD exhibited differences from controls for DKI measures and CBF in the left putamen and caudate. BD showed differences from controls for DKI measures in the left caudate. Additionally, BD showed lower Ka in right putamen, higher MD in right caudate compared with UD. Receiver operating characteristic analysis revealed the Kr of left caudate had the highest predictive power for distinguishing UD from controls. Conclusion: The two disorders may have overlaps in microstructural abnormality in basal ganglia. The change of caudate may serve as a potential biomarker for UD.

      • KCI등재
      • Synthesis of CuS/ZnO Nanocomposite and Its Visible-Light Photocatalytic Activity

        Zhu, Lianping,Zheng, Min,Lu, Juan,Xu, Mengfei,Seo, Hyo Jin Hindawi Limited 2014 Journal of nanomaterials Vol.2014 No.-

        <P>The CuS/ZnO nanocomposite was successfully synthesized by a simple mechanical method, without adding any surfactants. TEM images showed that CuS existed in the nanocomposite and the size of CuS/ZnO nanocomposite particle was around 35 nm. CuS worked as an electron absorber in the nanocomposite, which was beneficial for the improvement of photocatalysis of ZnO. It was also proved by the experiments performed under the visible light irradiation that CuS could help ZnO degrade methylene blue (MB). The catalytic efficiency of the nanocomposites reached the highest value when 0.5 wt% CuS was added. In addition, compared with pure ZnO, the CuS/ZnO nanocomposite exhibited a better photochemical stability up to 5 catalytic cycles. More importantly, CuS did not reduce the antibacterial property of ZnO. All these results indicated that as-prepared samples had some potential values in practical applications.</P>

      • KCI등재

        The Shear Behavior of Double-superposed Panels Reinforced with Different Shear Connectors

        Wenying Zhang,Lianping Yang,Shaole Yu,Junsheng Yan 대한토목학회 2018 KSCE JOURNAL OF CIVIL ENGINEERING Vol.22 No.10

        The shear behavior of a new type of sandwich structure, double-superposed panels, is investigated by conducting push-out test and finite element analysis in this paper. Experiments have been carried out to characterize the effect on the shear behavior of two different shear connector configurations: truss connector and tic-tac-toe connector. Based on finite element analysis, a parameter study is conducted, with the major parameters considered being the diameter, height and pitch of shear connector. Test results indicate that the delamination between the precast layers and core layer is the main failure mode for all specimens, and the crack formation and crack development between the two interfaces is not in synch. It’s also revealed that the specimens with tic-tac-toe connections present higher ultimate shear strength, as well as better ductility during the process of failure, compared to those with truss connections. The results of the numerical simulations show that the ultimate shear strength and the ductility of both connector configurations increases as the diameter of the shear connector increases; increasement in height of shear connector has a negligible effect on the shear behavior; when the pitch length is increased, the ultimate shear strength of the truss connector specimen increases, which is the inverse behavior of the specimen with tic-tac-toe connector.

      • KCI등재

        Advances in tourism behavior & retailing introduction to a special issue in Journal of Global Scholars of Marketing Science (JGSMS)

        Chen Po-Ju,Ren Lianping,Xiangping Li,Yang Fiona X. 한국마케팅과학회 2022 마케팅과학연구 Vol.32 No.1

        This introduction reviews current issues in tourist behaviors and retailing. The article furthers the retailing shopping framework and its application to consumer behavior in general and tourism and retailing in particular. A summary of each of the six articles that follow appears. The article extends a note of appreciation to the members of the special editorial board for this issue.

      • KCI등재

        NF-κB-Mediated Regulation of Osteoclastogenesis

        Brendan F. Boyce,Yan Xiu,Jinbo Li,Lianping Xing,Zhenqiang Yao 대한내분비학회 2015 Endocrinology and metabolism Vol.30 No.1

        Osteoclasts are multinucleated cells formed mainly on bone surfaces in response to cytokines by fusion of bone marrow-derived myeloid lineage precursors that circulate in the blood. Major advances in understanding of the molecular mechanisms regulating osteoclast formation and functions have been made in the past 20 years since the discovery that their formation requires nuclear factor-kappa B (NF-κB) signaling and that this is activated in response to the essential osteoclastogenic cytokine, receptor activator of NF-κB ligand (RANKL), which also controls osteoclast activation to resorb (degrade) bone. These studies have revealed that RANKL and some pro-inflammatory cytokines, including tumor necrosis factor, activate NF-κB and downstream signaling, including c-Fos and nuclear factor of activated T-cells, cytoplasmic 1 (NFATc1), and inhibition of repressors of NFATc1 signaling, to positively regulate osteoclast formation and functions. However, these cytokines also activate NF-κB signaling that can limit osteoclast formation through the NF-κB signaling proteins, TRAF3 and p100, and the suppressors of c-Fos/NFATc1 signaling, IRF8, and RBP-J. This paper reviews current understanding of how NF-κB signaling is involved in the positive and negative regulation of cytokine-mediated osteoclast formation and activation.

      • KCI등재

        Nuclear Factor-Kappa B Regulation of Osteoclastogenesis and Osteoblastogenesis

        Brendan F. Boyce,Jinbo Li,Zhenqiang Yao,Lianping Xing 대한내분비학회 2023 Endocrinology and metabolism Vol.38 No.5

        Maintenance of skeletal integrity requires the coordinated activity of multinucleated bone-resorbing osteoclasts and bone-forming osteoblasts. Osteoclasts form resorption lacunae on bone surfaces in response to cytokines by fusion of precursor cells. Osteoblasts are derived from mesenchymal precursors and lay down new bone in resorption lacunae during bone remodeling. Nuclear factorkappa B (NF-κB) signaling regulates osteoclast and osteoblast formation and is activated in osteoclast precursors in response to the essential osteoclastogenic cytokine, receptor activator of NF-κB ligand (RANKL), which can also control osteoblast formation through RANK-RANKL reverse signaling in osteoblast precursors. RANKL and some pro-inflammatory cytokines, including tumor necrosis factor (TNF), activate NF-κB signaling to positively regulate osteoclast formation and functions. However, these cytokines also limit osteoclast and osteoblast formation through NF-κB signaling molecules, including TNF receptor-associated factors (TRAFs). TRAF6 mediates RANKL-induced osteoclast formation through canonical NF-κB signaling. In contrast, TRAF3 limits RANKL- and TNF-induced osteoclast formation, and it restricts transforming growth factor β (TGFβ)-induced inhibition of osteoblast formation in young and adult mice. During aging, neutrophils expressing TGFβ and C-C chemokine receptor type 5 (CCR5) increase in bone marrow of mice in response to increased NF-κB-induced CC motif chemokine ligand 5 (CCL5) expression by mesenchymal progenitor cells and injection of these neutrophils into young mice decreased bone mass. TGFβ causes degradation of TRAF3, resulting in decreased glycogen synthase kinase-3β/β-catenin-mediated osteoblast formation and age-related osteoporosis in mice. The CCR5 inhibitor, maraviroc, prevented accumulation of TGFβ+/CCR5+ neutrophils in bone marrow and increased bone mass by inhibiting bone resorption and increasing bone formation in aged mice. This paper updates current understanding of how NF-κB signaling is involved in the positive and negative regulation of cytokine-mediated osteoclast and osteoblast formation and activation with a focus on the role of TRAF3 signaling, which can be targeted therapeutically to enhance bone mass.

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