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      • New Recursive Identification Algorithm for Time-Varying Systems

        Lianming Sun,Lin Li 제어로봇시스템학회 2009 제어로봇시스템학회 국제학술대회 논문집 Vol.2009 No.8

        A new recursive identification algorithm for time-varying systems is developed in this paper. It is demonstrated that the parameters of the time-varying model can be expressed by a nexplicit approximation using cosineseries. By using the or thogonal characteristics of basis functions, efficient updating of matrices and recursion of parameters are implemented in the algorithm. In contrast with the conventional basis function based methods, RLS and LMS algorithms, the proposed algorithm has less sensitivity to selection of basis functions and data window, and has higher tracking performance even in rapid varying processes.

      • KCI등재

        Emotion-aware Task Scheduling for Au-tonomous Vehicles in Software-defined Edge Networks

        Mengmeng Sun,Lianming Zhang,Jing Mei,Pingping Dong 한국인터넷정보학회 2022 KSII Transactions on Internet and Information Syst Vol.16 No.11

        Autonomous vehicles are gradually being regarded as the mainstream trend of future devel-opment of the automobile industry. Autonomous driving networks generate many intensive and delay-sensitive computing tasks. The storage space, computing power, and battery ca-pacity of autonomous vehicle terminals cannot meet the resource requirements of the tasks. In this paper, we focus on the task scheduling problem of autonomous driving in soft-ware-defined edge networks. By analyzing the intensive and delay-sensitive computing tasks of autonomous vehicles, we propose an emotion model that is related to task urgency and changes with execution time and propose an optimal base station (BS) task scheduling (OBSTS) algorithm. Task sentiment is an important factor that changes with the length of time that computing tasks with different urgency levels remain in the queue. The algorithm uses task sentiment as a performance indicator to measure task scheduling. Experimental results show that the OBSTS algorithm can more effectively meet the intensive and delay-sensitive requirements of vehicle terminals for network resources and improve user service experience.

      • KCI등재

        MED1 induces M2 polarization of tumor-associated macrophages to aggravate breast cancer

        Shen Ye,Zhou Lianming,Xu Meiyu,Tan Zhanhai,Yao Kai,Wang Wenjie 한국유전학회 2023 Genes & Genomics Vol.45 No.12

        Background Breast cancer is a common malignant tumor in female, and its 5-year survival rate remains low. The correlation between mediator subunit 1 (MED1) gene and macrophage phenotypic transformation may be a key factor affecting the therapeutic effect on cancer. Objective The present study intended to explore the role of MED1 in macrophage polarization and its further influence on the malignant behaviors of breast cancer. Methods Bioinformatics analysis was carried out to predict the expression pattern of MED1 in breast cancer. Flow cytometry was conducted to detect the effect of MED1 overexpression or silencing on macrophage polarization. ELISA was applied to analyze the effect of abnormal MED1 expression on cytokine secretion of macrophages. CCK-8, colony formation, Transwell and scratch healing assays were applied to investigate the effects of macrophage conditioned medium on the malignant behaviors of breast cancer cells. Results MED1 expression was prominently increased in M2 macrophages, and overexpression of MED1 significantly increased M2 polarization of tumor-associated macrophages (TAMs) and IL-10 cytokine level. Meanwhile, M2 macrophages with MED1 overexpression could significantly promote the malignant behaviors of breast cancer cells. Dasatinib rescue experiment further confirmed that MED1-induced M2 macrophage polarization could facilitate the malignant progression of breast cancer cells. Conclusion In summary, MED1 could induce M2 macrophage polarization and thus regulate the malignant behaviors of breast cancer cells.

      • KCI등재

        A Hybrid of Smartphone Camera and Basestation Wide-area Indoor Positioning Method

        ( Jichao Jiao ),( Zhongliang Deng ),( Lianming Xu ),( Fei Li ) 한국인터넷정보학회 2016 KSII Transactions on Internet and Information Syst Vol.10 No.2

        Indoor positioning is considered an enabler for a variety of applications, the demand for an indoor positioning service has also been accelerated. That is because that people spend most of their time indoor environment. Meanwhile, the smartphone integrated powerful camera is an efficient platform for navigation and positioning. However, for high accuracy indoor positioning by using a smartphone, there are two constraints that includes: (1) limited computational and memory resources of smartphone; (2) users` moving in large buildings. To address those issues, this paper uses the TC-OFDM for calculating the coarse positioning information includes horizontal and altitude information for assisting smartphone camera-based positioning. Moreover, a unified representation model of image features under variety of scenarios whose name is FAST-SURF is established for computing the fine location. Finally, an optimization marginalized particle filter is proposed for fusing the positioning information from TC-OFDM and images. The experimental result shows that the wide location detection accuracy is 0.823 m (1σ) at horizontal and 0.5 m at vertical. Comparing to the WiFi-based and ibeacon-based positioning methods, our method is powerful while being easy to be deployed and optimized.

      • KCI등재

        A Classification-Based Virtual Machine Placement Algorithm in Mobile Cloud Computing

        ( Yuli Tang ),( Yao Hu ),( Lianming Zhang ) 한국인터넷정보학회 2016 KSII Transactions on Internet and Information Syst Vol.10 No.5

        In recent years, cloud computing services based on smart phones and other mobile terminals have been a rapid development. Cloud computing has the advantages of mass storage capacity and high-speed computing power, and it can meet the needs of different types of users, and under the background, mobile cloud computing (MCC) is now booming. In this paper, we have put forward a new classification-based virtual machine placement (CBVMP) algorithm for MCC, and it aims at improving the efficiency of virtual machine (VM) allocation and the disequilibrium utilization of underlying physical resources in large cloud data center. By simulation experiments based on CloudSim cloud platform, the experimental results show that the new algorithm can improve the efficiency of the VM placement and the utilization rate of underlying physical resources.

      • KCI등재

        Taxonomic Revision of the Nematode-Trapping Fungus Arthrobotrys multisecundaria

        Juan Li,Jinkui Yang,Lianming Liang,Ke-Qin Zhang 한국미생물학회 2008 The journal of microbiology Vol.46 No.5

        The gene encoding an extracellular serine protease was cloned from Arthrobotrys multisecundaria using degenerate primers. The gene was highly similar (99.26%) to protease Mlx from Monacrosporium microscaphoides. To clarify the taxonomic relationship between these species, genes encoding the internal transcribed spacer (ITS) and β-tubulin were also cloned and sequenced from A. multisecundaria and M. microscaphoides, respectively. Homologous analysis of the nuclear (ITS) and protein (β-tubulin) encoding genes showed that the two species of nematode-trapping fungi also shared extensive identity (99.82 and 99.63%, respectively), although they exhibited obvious differences in secondary conidia morphology. Accordingly, a taxonomic revision is recommended, with A. multisecundaria being revised as A. microscaphoides var. multisecundaria. In addition, the identified mutation may better facilitate the study of the sporulation of nematode-trapping fungi.

      • SCISCIESCOPUS

        Arrays of horizontal carbon nanotubes of controlled chirality grown using designed catalysts

        Zhang, Shuchen,Kang, Lixing,Wang, Xiao,Tong, Lianming,Yang, Liangwei,Wang, Zequn,Qi, Kuo,Deng, Shibin,Li, Qingwen,Bai, Xuedong,Ding, Feng,Zhang, Jin Macmillan Publishers Limited, part of Springer Nat 2017 Nature Vol.543 No.7644

        <P>The semiconductor industry is increasingly of the view that Moore's law-which predicts the biennial doubling of the number of transistors per microprocessor chip-is nearing its end(1). Consequently, the pursuit of alternative semiconducting materials for nanoelectronic devices, including single-walled carbon nanotubes (SWNTs), continues(2-4). Arrays of horizontal nanotubes are particularly appealing for technological applications because they optimize current output. However, the direct growth of horizontal SWNT arrays with controlled chirality, that would enable the arrays to be adapted for a wider range of applications and ensure the uniformity of the fabricated devices, has not yet been achieved. Here we show that horizontal SWNT arrays with predicted chirality can be grown from the surfaces of solid carbide catalysts by controlling the symmetries of the active catalyst surface. We obtained horizontally aligned metallic SWNT arrays with an average density of more than 20 tubes per micrometre in which 90 per cent of the tubes had chiral indices of (12, 6), and semiconducting SWNT arrays with an average density of more than 10 tubes per micrometre in which 80 per cent of the nanotubes had chiral indices of (8, 4). The nanotubes were grown using uniform size Mo2C and WC solid catalysts. Thermodynamically, the SWNT was selectively nucleated by matching its structural symmetry and diameter with those of the catalyst. We grew nanotubes with chiral indices of (2m, m) (where m is a positive integer), the yield of which could be increased by raising the concentration of carbon to maximize the kinetic growth rate in the chemical vapour deposition process. Compared to previously reported methods, such as cloning(5,6), seeding(7,8) and specific-structure-matching growth(9-11), our strategy of controlling the thermodynamics and kinetics offers more degrees of freedom, enabling the chirality of as-grown SWNTs in an array to be tuned, and can also be used to predict the growth conditions required to achieve the desired chiralities.</P>

      • KCI등재

        Design of 39-GHz Up- and Down-Conversion Mixers for 5G mmWave TDD Applications

        Wang Yi-Yang,Duan Haipeng,He Long,Wu Xu,Wang Dongming,Li Lianming 한국전자파학회 2023 Journal of Electromagnetic Engineering and Science Vol.23 No.2

        This article presents fully integrated 39-GHz bidirectional up- and down-conversion mixers for 5G millimeter-wave (mmWave) applications. Fabricated in a 65-nm CMOS process with a 1.2-V supply voltage, the up- and down-conversion mixers consume 39 and 43 mW, respectively. For 5G time-division duplexing (TDD) operation, intermediate-frequency (IF)/local-oscillator (LO)/radio-frequency (RF) T/R switches are introduced. For better isolation and low insertion loss between the up- and down-conversion mixer, a series-shunt singlepole double-throw (SPDT) structure and an equivalent lumped λ/4 transmission line are proposed for IF and RF T/R switches, respectively. To realize compact area and wide bandwidth, a transformer-based matching network is adopted in this design. Targeting multi-channel phased array applications, the measurement result shows that the up-conversion mixer achieves a 2.5-dB peak conversion gain with 6.5 GHz 3-dB bandwidth. Including the insertion loss of the switch and IF signal routing, at the maximum gain of 36.5 GHz, the up-conversion mixer achieves an output 1-dB gain compression point (OP1dB) of 2.5 dBm. Furthermore, the down-conversion mixer achieves a 5-dB peak conversion gain with a 9.7-GHz 3-dB bandwidth.

      • KCI등재

        Active hexose correlated compound potentiates the antitumor effects of low-dose 5-fluorouracil through modulation of immune function in hepatoma 22 tumor-bearing mice

        Zhiyun Cao,Xuzheng Chen,Lan Lan,Zhideng Zhang,Jian Du,Lianming Liao 한국영양학회 2015 Nutrition Research and Practice Vol.9 No.2

        BACKGROUND/OBJECTIVES: A variety of immunomodulators can improve the efficacy of low-dose chemotherapeutics. Active hexose correlated compound (AHCC), a mushroom mycelia extract, has been shown to be a strong immunomodulator. Whether AHCC could enhance the antitumor effect of low-dose 5-fluorouracil (5-FU) via regulation of host immunity is unknown. MATERIALS/METHODS: In the current study Hepatoma 22 (H22) tumor-bearing mice were treated with PBS, 5-FU (10 mg?kg<SUP>-1</SUP>?d<SUP>-1</SUP>, i.p), or AHCC (360 mg?kg<SUP>-1</SUP>?d<SUP>-1</SUP>, i.g) plus 5-FU, respectively, for 5 d. CD3<SUP>+</SUP>, CD4<SUP>+</SUP>, CD8<SUP>+</SUP>, and NK in peripheral blood were detected by flow cytometry. ALT, AST, BUN, and Cr levels were measured by biochemical assay. IL-2 and TNFα in serum were measured using the RIA kit and apoptosis of tumor was detected by TUNEL staining. Bax, Bcl-2, and TS protein levels were measured by immunohistochemical staining and mRNA level was evaluated by RT-PCR. RESULTS: Diet consumption and body weight showed that AHCC had no apparent toxicity. AHCC could reverse liver injury and myelosuppression induced by 5-FU (P < 0.05). Compared to mice treated with 5-FU, mice treated with AHCC plus 5-FU had higher thymus index, percentages of CD3<SUP>+</SUP>, CD4<SUP>+</SUP>, and NK cells (P < 0.01), and ratio of CD4<SUP>+</SUP>/CD8<SUP>+</SUP> (P < 0.01) in peripheral blood. Radioimmunoassay showed that mice treated with AHCC plus 5-FU had the highest serum levels of IL-2 and TNFα compared with the vehicle group and 5-FU group. More importantly, the combination of AHCC and 5-FU produced a more potent antitumor effect (P < 0.05) and caused more severe apoptosis in tumor tissue (P < 0.05) compared with the 5-FU group. In addition, the combination of AHCC and 5-FU further up-regulated the expression of Bcl-2 associated X protein (Bax) (P< 0.01), while it down-regulated the expression of B cell lymphoma 2 (Bcl-2) (P < 0.01). CONCLUSIONS: These results support the claim that AHCC might be beneficial for cancer patients receiving chemotherapy.

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