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Na Cao,Huiling Du,Jun Liu,Lianli Wang 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2018 NANO Vol.13 No.1
Bi4Ti3O12/Bi2S3 heterostructures with enhanced visible light photocatalytic activity are successfully synthesized via a two-step synthesis route based on a sol–gel hydrothermal method and a subsequent hydrothermal-ion exchange reaction technique. The structures, composition, morphologies and light absorption capability of Bi4Ti3O12/Bi2S3 heterostructures are verified by XRD, XPS, SEM, TEM and UV-Vis diffuse reflectance spectra, respectively. Results indicated that Bi2S3 nanorods are grown on the surface of the spherical structure assembled by criss-cross nanosheets of Bi4Ti3O12 after ion exchange reaction. The photocatalytic tests reveal that the Bi4Ti3O12/Bi2S3 heterostructures showed much higher photocatalytic activity than pure Bi4Ti3O12 or Bi2S3. The tight interconnection between the two semiconductors will facilitate the photoinduced carriers' separation. Owing to the easy preparation and excellent property, the obtained Bi4Ti3O12/Bi2S3 heterostructures may be promising photocatalysts for practical application.
Transcriptome sequencing and analysis of sweet osmanthus (Osmanthus fragrans Lour.)
Hong Na Mu,Liang Gui Wang,Huo Gen Li,Xiu Lian Yang,Tao Ze Sun,Chen Xu 한국유전학회 2014 Genes & Genomics Vol.36 No.6
Osmanthus fragrans is a woody, evergreenspecies of shrubs and small trees that is extensively plantedin sub-tropical and temperate climates as an ornamentalplant in gardens and for its health benefits. The flower colorranges from ivory to orange to pink among different varietiesand even color difference during the whole blossom inthe sweet osmanthus. Sweet osmanthus is widely cultivatedthroughout China and other countries due to its prominentfragrance, colorful flowers, and medicinal properties. However, the scanty genomic resources in the Olea familyhave greatly hindered further exploration of its geneticmechanism on these economically important traits. In thisstudy, transcriptome sequencing of O. fragrans was performedusing the Illumina HighSeqTM2000 sequencingplatform. Next generation sequencing (NGS) of the transcriptomeof O. fragrans produced 31.7G of clean bases(211,266,818 clean reads) that were assembled into256,774 transcripts and 117,595 unigenes. Of them, 197and 237 candidate genes involved in fragrance and pigmentbiosynthesis respectively were identified based on functionannotation. Meanwhile, 1 unnamed protein and 468 functionalunknown genes were also identified. Furthermore,mRNA sequencing expression profiling of O. fragranswere compared to previous genes’. In summary, thiscomprehensive transcriptome dataset allows the identificationof genes associated with several major metabolicpathways and provides a useful public information platformfor further functional genomic studiesin O. fragransLour.
STRUCTURAL DESIGN OF SPECIAL VEHICLE COMPONENTS BASED ON TOPOLOGY OPTIMIZATION
Wu Na,Liu Chao,Yang Zhian,Lian Zhaolun 한국자동차공학회 2023 International journal of automotive technology Vol.24 No.2
With the development of the economy, the demand for heavy-duty transportation vehicles is increasing. Due to the limitations of national standards and regulations, and the market’s requirements for the reliability and economy of the whole vehicle, it is urgent to optimize the structure of each part of the heavy-duty transportation vehicle. In this paper, the sub-frame of a certain type of cement mixer truck is taken as an example. Firstly, the finite element analysis method is used to find the structural defects of the existing products through static analysis and modal analysis of the existing products under full-load condition. Then, the density method is used to carry out topology optimization design of the existing sub-frame structure, and the optimized frame is checked. The conclusion is expected to provide a theoretical basis for the lightweight design of heavy transport vehicles.
Zhao, Lian-Mei,Han, Li-Na,Ren, Feng-Zhi,Chen, Shu-Hong,Liu, Li-Hua,Wang, Ming-Xia,Sang, Mei-Xiang,Shan, Bao-En Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.8
Cochinchina momordica seeds (CMS) have been widely used due to antitumor activity by Mongolian tribes of China. However, the details of the underlying mechanisms remain unknown. In the present study, we found that an EtOAc (ethyl ester) extract of CMS (CMSEE) induced differentiation and caused growth inhibition of melanoma B16 F1 cells. CMSEE at the concentration of $5-200{\mu}g/ml$ exhibited strongest anti-proliferative effects on B16 F1 cells among other CMS fractions (water or petroleum ether). Moreover, CMSEE induced melanoma B16 F1 cell differentiation, characterized by dendrite-like outgrowth, increasing melanogenesis production, as well as enhancing tyrosinase activity. Western blot analysis showed that sustained phosphorylation of p38 MAP accompanied by decrease in ERK1/2 and JNK dephosphorylation were involved in CMSEE-induced B16 F1 cell differentiation. Notably, 6 compounds that were isolated and identified may be responsible for inducing differentiation of CMSEE. These results indicated that CMSEE contributes to the differentiation of B16 F1 cells through modulating MAPKs activity, which may throw some light on the development of potentially therapeutic strategies for melanoma treatment.
Guo, Lian Yu,Hung, Tran Manh,Bae, Ki Hwan,Shin, Eun Myoung,Zhou, Hong Yu,Hong, Yoo Na,Kang, Sam Sik,Kim, Hyun Pyo,Kim, Yeong Shik Elsevier 2008 european journal of pharmacology Vol.591 No.1
<P><B>Abstract</B></P><P>Schisandrin is the main active ingredient isolated from the fruit of <I>Schisandra chinensis</I> Baill. Recent studies have demonstrated that schisandrin exhibits anti-oxidative effects <I>in vivo</I>. In the present study, the effect of schisandrin on plasma nitrite concentration in lipopolysaccharide (LPS)-treated mice was evaluated. It also significantly inhibited carrageenan-induced paw edema and acetic acid-induced vascular permeability in mice. Furthermore, schisandrin had a protective effect on lipopolysaccharide (LPS)-induced sepsis. <I>In vitro</I>, our results are the first that show that the anti-inflammatory properties of schisandrin result from the inhibition of nitric oxide (NO) production, prostaglandin E<SUB>2</SUB> (PGE<SUB>2</SUB>) release, cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS) expression, which in turn results from the inhibition of nuclear factor-kappaB (NF-κB), c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein kinase (MAPK) activities in a RAW 264.7 macrophage cell line.</P>
Liu, Meng,Cui, Lian-Hua,Ma, Ai-Guo,Li, Na,Piao, Jin-Mei Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.5
Background: Epidemiological findings are controversial relating to the relationship between dietary folate intake and the risk of breast cancer. We therefore conducted a meta-analysis of prospective cohort studies to clarify this association. Materials and Methods: PUBMED, EMBASE, and MEDLINE databases were searched for all relevant literature published in English from January 1, 1966 to August 2013. Summary relative risk (RR) and 95% confidence intervals (CIs) were calculated using a fixed or random effects model. Results: Dietary folate intake was not significantly associated with the risk of breast cancer. The combined RR with 95%CI for the highest vs. lowest category dietary intake of folate [fifteen studies; 1,836,566 participants and 24,083 patients with breast cancer] was 0.98 (0.90-1.05). Among subgroup analysis by menstrual status, hormonal status and the consumption of alcohol, methionine and vitamin B12, no significant association was observed for the dietary intake of folate and the risk of breast cancer. Dose-response analysis showed that a 220 ${\mu}g/day$ increment in dietary folate intake was not associated with the risk of breast cancer. Conclusions: Our findings indicate that dietary folate intake has no significant effect on the risk of breast cancer.
온라인 협업 도구 활용 한국어 수업 사례 : 상해 삼달대학교를 중심으로
배영련(Pei, Ying Lian),오선자(Wu, Shan Zi),최선진(Choi, Seon Jin),한나(Han, Na),오영화(Wu, Ying Hua) 글로벌교육연구학회 2021 글로벌교육연구 Vol.13 No.4
본 연구는 온라인 수업에서의 상호작용에 도움을 주며, 중국과 한국에서 동시에 사용할수 있는 다양한 온라인 협업 도구를 소개하고, 이 도구 네 가지(mentimeter, zoom, padlet, Quizizz)를 사용하여 중국인 대상 한국어 수업을 운영한 사례를 제시하였다. 그리고본 수업 운영에 대한 학습자 만족도를 살펴보기 위하여 2021학년도 3월 학기에 본 수업을수강한 상해 삼달대학교 한국어 학습자 75명을 대상으로 만족도 조사를 시행하였으며, 그결과 전체적인 수업 만족도는 평균 4.09였다. 또한, 온라인 수업에서의 상호작용 향상을위한 방법으로 활용한 온라인 협업 도구에 대한 전체적인 만족도는 4.24였으며, 각 도구의만족도는 mentimeter가 4.63, zoom이 4.15, padlet이 4.09, Quizizz 3.81 순이었다. 이 중에서 협업 도구에 대한 전체적인 만족도와 padlet 만족도가 수업 전체 만족도에 영향을미치는 것으로 분석되었다. 본 연구 결과에 따른 제언은 다음과 같다. 첫째, 온라인 협업도구 활용에 대한 학습자 만족도가 높기 때문에 한국어 수업에 활용할 수 있는 다양한 협업도구 연구를 바탕으로 수업 적용이 필요하며, 각 국 학습자용 교재 편찬이 필요하다고 할수 있다. 본 연구는 다양한 온라인 수업에서의 상호작용에 필요한 다양한 협업 도구를 소개하고 비대면 수업에서의 실제 활용방안을 제시했으며, 이에 대한 학습자들의 의견을 수렴했다는 점에서 의의가 있다. This study was to present a case of an Online Korean class using four online tools such as Mentimeter, Zoom, Padlet, Quizizz for helping the interaction of Korean and Chinese students. To investigate learner satisfaction, 75 Chinese students from Shanda University participated in a survey after the class. The results were as follows: First, the overall class satisfaction was 4.09, especially students were satisfied with using collaboration tools. Second, online tool satisfaction was 4.63 for Mentimeter, 4.15 for Zoom, 4.09 for Padlet, and 3.81 for Quizizz in the order of the program. Based on the results, it was suggested applications of various online tools into class and textbooks for learners. At last, it was significant that the case of online Korean class was presented with many online tools and learners satisfaction in this study.
Core Binding Factor β of Osteoblasts Maintains Cortical Bone Mass Via Stabilization of Runx2 in Mice
Lim, Kyung-Eun,Park, Na-Rae,Che, Xiangguo,Han, Min-Su,Jeong, Jae-Hwan,Kim, Shin-Yoon,Park, Clara Yongjoo,Akiyama, Haruhiko,Kim, Jung-Eun,Ryoo, Hyun-Mo,Stein, Janet L,Lian, Jane B,Stein, Gary S,Choi, J Wiley (John WileySons) 2015 Journal of bone and mineral research Vol.30 No.10