VP-16으로 성공적으로 치료된 위 Kaposi 육종 1예

양웅석,송근암,조몽,이재승,송철수,김형욱,김영민,이수봉,김태오,이성훈 대한소화기내시경학회 1999 Clinical Endoscopy Vol.19 No.4

The skin is an uncommon site of distant metastasis from any internal malignancy, and the incidence of metastatic skin lesions as the first symptom of disease is only 0.8% in patients with all systemic malignancies. Furthermore, cutaneous metastasis from adenocarcinoma of the stomach has been found to be extremely rare. A 35-year-old female patient was admitted due to multiple cutaneous nodules in her chest, abdomen, and back. A gastroendoscopic examination and biopsy was made according to the results of skin pathologic findings. Stomach and skin biopsy results revealed a signet ring cell type of adenocarcinoma. A case of gastric adenocarcinoma in which metastatic skin nodules appeared as the first sign of disease, is here in reported with a review of related literature.

A comparison of survival outcome of open, total laparoscopic and laparoscopy-assisted vaginal radical hysterectomy in patients with early cervical cancer of stage IB2

( Sul Lee ),( Hyung Joon Yoon ),( Eun Hye Jeon ),( Juseok Yang ),( Yong Jung Song ),( Hyun Jin Roh ),( Sang Hun Lee ),( Byung Su Kwon ),( Ki Hyung Kim ),( Dong Soo Suh ) 대한산부인과학회 2019 대한산부인과학회 학술대회 Vol.105 No.-

Objective: The aim of this study is to evaluate oncologic outcomes of total abdominal radical hysterectomy (TARH), total laparoscopic radical hysterectomy (TLRH) and laparoscopic-assisted radical vaginal hysterectomy (LARVH) in early cervical cancer patients (stage IB2-3, tumor size≥2cm), analyzing the risk factors that may affect the clinical results. Methods: A total of 756 patients underwent radical hysterectomy between 2000 and 2019 from three university hospitals (Pusan National University Hospital, Yang-san Pusan National University Hospital, Ulsan University Hospital) were enrolled. Among them, 172 patients with stage IB2-3 were analyzed retrospectively. Results: Seventy-seven patients were treated with TARH, and 95 were managed via minimally invasive surgery (MIS), consisting of 35 with TLRH and 60 with LARVH. TARH group had better disease five-year disease free survival (DFS) and overall survival (OS) compared with MIS group (86.4% vs. 73.4 for DFS and 91.7 vs. 82.2 for OS), but not statistically significant in both (p=0.058 for DFS and p=0.119 for OS). When TARH and the LARVH group were compared, both five-year DFS and OS were not significant different (86.4 vs 82.2%; p=0.288 for DFS and 91.7 vs 84.4%; p=0.206 for OS). However, when TARH and the TLRH group were compared, TLRH group had significantly worse five-year DFS than TARH (86.4 vs 54.5%; p=0.008), but five-year OS was not significant different (91.7 vs 77.5%; p=0.127). Multivariate analysis showed that LN metastasis and TLRH surgical approaches were an independent prognostic factor for DFS in IB2-3 cervical cancers. Conclusion: Our findings provided the evidence that TLRH surgical approach was associated with worse DFS in IB2-3 cervical cancers but that of LARVH was not. Such results may have important implications of colpotomy method for MIS in cervical cancer.

Bortezomib과 Dexamthasone으로 치료한 골수외 형질세포종 4예

백종현,이은영,장리라,손창배,신은경,서정아,이지숙,이호섭,이상민,신성훈,김양수 고신대학교의과대학 2007 고신대학교 의과대학 학술지 Vol.22 No.2

Despite the use of aggressive local and systemic treatment including autologous stem cell transplantation in multiple myeloma, extramedullary recurrences are common and the prognosis of these patients is poor. Many novel drugs such as thalidomide, lenalidomide and bortezomib improve the response of treatment of multiple myeloma, but some reports failed to describe thalidomide has effect in extramedullary plasmacytoma. Recent data report on the successful treatment plasmacytomas with bortezomib in patients with advanced multiple myeloma. We treated 4 relapsed or refractory extramedullary plasmacytomas with bortezomib at our institution. We recognized all these extramedullary plasmacytomas decreased and showed more than partial response. This report lends support to the efficacy of bortezomib in the treatment of plasmacytoma and describes the safe use of bortezomib. Responses may, however, be of short duration. Therefore, despite our limited experience, we propose that bortezomib may be considered a therapeutic option for such patients who have risk of radiation therapy

V.I.S.의 槪念 및 製作에 關한 考察 : Concentrated of the V.I.S. Manual of Samchok National University 三陟大學校의 V.I.S. Manual을 中心으로

李允洙,全洋德 三陟大學校 1992 論文集 Vol.25 No.-

Beginning with the industrial revolution in England, spreaded rapidly into European countries, the design movement, new artistic concept, faced with a new phase because of more developed industrial technique and international age. Identity concept in design, with industrial diversity, specialization, internationalization, resulted from the work called 'Visual Identification Standards.' Samchok National University, elevated into four-years' academic system in 1991, has taken a new opportunity of making progress. Keeping pace with the new image, the introduction to Visual Identification Standard is followed necessarily according to the current trend. The V.I.S. Manual has been attempted by general concept. Some problems on the overall plan, design process, and management in the Manual are as follows; 1. It has not gone through the broad convergence of opinions. That is, the identity n ideal system has not ben established. But the Visual Standard of identity was committed. 2. The Visual Identification Standard has been published into a Manual. But it has been used missunderstandingly, or subjectivelly. 3. For the unified image, it should be widely used, and the visual unfamiliarization should be eliminated. Thus, V.I.S. Manual of Samchok National University should be sufficed gradually according to the various phases. In a broad view, the re-design concept should be examined and thoroughly.

경부외측종괴의 감별진단 및 접근에 대한 고찰

이경호,박현진,강지연,최희원,조용석,김경원,양수남 大韓顎顔面成形再建外科學會 2002 Maxillofacial Plastic Reconstructive Surgery Vol.24 No.6

Most neck masses of specific cause occur in rather predictable locations within typical age groups. This allows a systematic approach to developing a working diagnosis and a differential diagnosis and management plan for the patient presenting with a neck mass. Pathologic masses of the neck will be divided into the following segment: 1. Masses of nonspecific location. 2. Masses in the submandibular region, 3. Masses in the parotid region, 4. Masses in the median-paramedian region, 5. Masses in the lateral neck region. The lateral neck region is the area posterior to the hyolaryngotracheal conduit, below the posterior belly of the digastric muscle and tip of the parotid gland, and extends down to the clavicle. The contents of this region include the large vessels, nerves and greatest number of lymph nodes of the neck, and lymph node metastasis in this region is usually from a primary lesion at the base of the tongue or elsewhere in the oropharynx. Common lateral neck masses include branchial cleft cyst, carotid body tumor, neurogenic tumor, pan-neck infection, cystic hygroma, hemangioma, lipoma and lymphoma. Especially lymphosarcoma. Hodgkin's disease, cystic hygroma, hemangioma and branchial cleft cyst and more common and often manifest in the young patients. Many head and neck disease processes manifest as neck masses. These conditions are treated by surgical excision, except for some inflammatory masses, and often those also must be excised before a diagnosis can be made. We retrospectively reviewed 5-year experiences in the treatment of lateral neck masses at our department to define better clinical characteristics of the masses and the optimal diagnostic and therapeutic approaches to these rare diseases.

跆拳道 앞차기時 스탠스 差異에 따른 全身反應時間에 關한 硏究

李秀川,梁昌秀 慶北大學校 師範大學 體育學硏究會 1986 體育學會誌 Vol.14 No.-

The purpose of the study was to investigate changes of whole body reaction time in accordance with 3 different stances. The subjects were 3 male national caliber Tae Kwan Do players. The 3 different stances were 1 standard stance (natural stride of each subject), 2 comparable stance (natural stride of each subject-1/2 foot length, natural stride of each subject+1/2 foot length). The reselts were summarized as follow; 1. In case of subject A, the whole body reaction time were 0.223sec in standard stance, 0.325 sec in -1/2 foot length stance, and 0.364 sec in+1/2 foot length stance. But these were no significant differences except between standard stance and +1/2 foot length stance (p<0.5). 2. In case of subject B, the whole body reaction time were 0.446 sec in standard stance, 0.447 sec in +1/2 foot length stance, 0.473 sec in -1/2 foot length stance. There were not significant differences among the stances. 3. In case of subject C, the whole body reaction time were 0.374 sec in +1/2 foot length stance, 0.399 sec in standard stance, 0.405 sec in 1/2 foot length stance. But there were no significant differences among the stances. 4. In case of total stances, the whole body reaction time were 0.357 sec in standard stance, 0.395 sec in +1/2 foot length stance, 0.401 sec in -1/2 foot length stance. But there were no significant differences among the stances.

조세순응성향과 조세회피행위에 관한 연구 : 봉급생활자와 자영업자를 중심으로 Focus on salaried employees and self-employed business people

李良玄,崔林洙 중앙대학교 산업경영연구소 1997 산업경영연구 Vol.6 No.1

The purpose of this study was to analyze factors influencing taxpayers'propensity to comply tax and tax evasion behavior, and to test if taxpayers' propensity to comply tax influences taxpayers' tax evasion behavior as a mediating variable. Pearson Correlation Analysis showed that almost tax ethical variable and taxpayer knowledge variable were significantly and positively related to tax propensity to comply tax, but on the contrary almost tax institutional variable and socio-cultural variable were significantly and negatively related to tax propensity to comply tax. Multiple Regression Analyses revealed that almost tax ethical variable and taxpayer knowledge variable emerged as significant positive predictors for propensity to comply tax, however almost tax institutional variable and socio-cultural variable were significant negative ones for propensity to comply tax. Logistic Regression Analyses showed almost tax ethical variable, tax psychological variable and propensity to comply tax variable to be significant negative predictors of taxpayer' tax evasion behavior, but almost tax institutional variable and taxpayer knowledge variable to be significant positive predictors of taxpayers' tax evasion behavior. And Logistic Regression Analyses also revealed that propensity to comply tax variable acted as a mediator variable between tax ethical variable, tax institutional variable, tax psychological variable, taxpayer knowledge variable, and socio-cultural variable and taxpayers' tax evasion behavior.

수술로 치험한 해면상 림파혈관종 2 예

이양행,황윤호,우종수,조광현,박동식 인제대학교 1984 仁濟醫學 Vol.5 No.4

Lymphangiomas are divided into three categories; (1) simple (capillary) lymphangioma, (2) cavernous lymphangioma, and (3) cystic hygroma. This lesion usually occurs in the posterior triangle of the neck but can be present in the axilla, mediastinum, or groin. Recently, we have experienced two cases of cavernous lymphangioma that one occurred in the mediastinum and the other was in the right chest wall, which were surgically removed successfully and confirmed histopathologically.

Cu-Al-Ni계 형상기억리본의 결정립크기 및 미세조직에 미치는 휠 회전속도의 영향

이영수,이수홍,장우양,강조원 조선대학교 생산기술연구소 2000 生産技術硏究 Vol.22 No.1

To improve mechanical properties of Cu-Al-Ni alloy by the grain refinement, Cu-Al-Ni SMA ribbons were fabricated by melt spinning apparatus. The variations of microstructure, transformation characteristics and mechanical properties with wheel speed were investigated in Cu-Al-Ni SMA ribbons. The ribbons fabricated by melt spinning obtained around 1.5mm in width and 50∼60㎛ in thickness. With increasing wheel speed in order of 10m/s, 15m/s, 20m/s, 30m/s and 35m/s, the grain size was decreased in order of 10㎛, 6㎛, 5㎛, 3㎛ and 3㎛. M_(s) and A, temperatures were decreased with decreasing grain size By X-ray diffraction test, ordered β_1 phase was observed in all the SMA ribbons and the volume friction of it was increased with increasing wheel speed. With increasing wheel speed, strain was increased from 4.8% to 5.8% and fracture mode has changed from mixture of intergranular and dimple fracture to mixture of fiber structure and dimple fracture

우묵사스레피(Eurya emarginata)의 플라보노이드 화합물의 분리 및 동정

양홍철,박수영,강희경,이남호 제주대학교 생명과학연구소 2001 제주생명과학연구 Vol.4 No.-

The extracts of Eurya emarginata showed inhibitory effect on the growth of HL-60 leukemia cells. So, 80% methanol(MeOH) extract of its leaves was partitioned to hexane, ethyl acetate, n-butanol and residual water fractions. The ethyl acetate fraction, which showed desirable activities, was further purified using SiO2 column chromatography(CC) followed by reverse phase silica gel CC, then another normal CC to give fraction 4-1-8 as a pure compound. The compound 4-1-8 was analyzed by NMR spectrometry using 1H, 13C, DEPT, HMQC and HMBC spectra, and finally proved to be well-known flavono glycoside, Quercitrin.