한라산 주변에 발생하는 Karman Vortex Street 재현

권지혁(Kwon Ji-hyuk·Lee),이연원(Lee Yeon-won),김영덕(Kim Young-duk),박광열(Park Kwang-yul) 한국풍공학회 2006 한국풍공학회지 Vol.10 No.1

늦가을과 초본 사이 제주도 후면에 Karman vortex street가 발생한다. 이러한 vortex가 발생하기 위해서는 기온 역전층과 5 ~ 13 m/s의 지속적인 바람이 필요하다는 것을 밝히기 위한 많은 연구들이 있었다. 이러한 vortex clouds는 발생 후 주 풍향의 방향을 이동하게 된다. Karman vortex street는 기상학에서 매우 흥미로운 주제이다. 본 연구에서는 LES 난류 모델을 이용하여 Karman vortex street에 관한 해석을 수행하고 수치해석을 통해 얻은 결과와 기상 데이터가 일치함을 보였다. From late autumn to the beginning of the spring, the phenomena of the Karman vortex street have been frequently observed in the wake of Mt. Halla in the Jeju island. Some researches revealed that the necessary conditions for development of these vortex clouds are a strong low-level inversion of temperature and a persistent wind speed of 5 to 13m/s. After the cloud is formed, the vortex clouds are shed from alternating sides of Jeju island and then move downwind with main airflow stream. The Karman vortex street in the wake of the Jeju island was one of the interesting topics in meteorology. In this study, CFD using LES turbulence model was developed to investigate the Karman vortex street and the results of CFD showed a good agreement with weather data.

생태시범도시 조성을 위한 계획모형 구축에 관한 연구

이광국(Lee Kwang-Kug),김청원(Kim Chung-Won) 한국주거환경학회 2005 주거환경(한국주거환경학회논문집) Vol.3 No.1

  The security of municipal competitiveness is the most important in the age of limitless competition of localization and globalization. The authority of city planning which has been exercised by central governments was mostly or is being transferred to local governments. At this point of time, it is no exaggeration to say that the creation of abundant and advanced municipal environment for 21st century ahead wholly depends on the efforts of local governments.<BR>  The ecological model project was introduced as a connecting support and link between central and local governments. The ecological model project will play a role in city policies ahead as a win-win strategy. Therefore, this study is aimed at establishing the most preferentially required planning model during the propulsion of the ecological model city project.<BR>  For the planning model establishment of the ecological city project, the security of purpose coincidence and public interest are required because the ecological city project is focused on efficient propulsion not like existing city development projects. For this, fund raising, citizen participation and citizen corporation should be preferentially considered from the aspect of project performance possibility. Also, the introduction of an evaluation monitoring system for appropriateness evaluation is needed.<BR>  From the result of the planning model establishment of this study, the model was divided into 11 stage procedures such as problem recognition, suggestion & announcement of proposed sites for the project, evaluation & selection of proposed sites, drawing up of project performance guideline, drawing up & presentation of project plan, selection of project"s main body, drawing up of detailed project plan, examination & authentication of detailed project plan, project execution, evaluation & authentication of project execution, evaluation & authentication of after management.

과학기술정보콘텐츠 통합관리시스템 구축을 위한 데이터 마이그레이션 모델 수립 및 적용 사례

신성호(Sung-Ho Shin),이민호(Min-Ho Lee),이원구(Won-Goo Lee),윤화묵(Hwa-Mook Yoon),성원경(Won-Kyung Sung),김광영(Kwang-Young Kim) 한국컴퓨터정보학회 2011 韓國컴퓨터情報學會論文誌 Vol.16 No.11

국내 데이터베이스 구축 시장은 작년 기준으로 3조 6,633억원 규모로 추정된다. 데이터베이스 산업의 지속적인 성장과 맞물려, 데이터 마이그레이션의 중요성도 날로 높아지고 있다. 고객 위치를 찾아주는 g-CRM이나 고객에게 상품을 추천하는 맞춤 설계 기능 등은 모두 고객 데이터베이스, 상품 데이터베이스, 지리정보 데이터베이스 등이 결합되어야 구현 가능한 서비스들이다. 스마트 비즈니스의 핵심 인프라도 통합되고 완전하며 신뢰할 수 있는 데이터베이스라고 할 수 있다. 이러한 데이터베이스의 중요성에도 불구하고, 데이터 마이그레이션 및 통합 과정의 효율적인 수행 방안이나 데이터 검증 방법에 대하여는 구체적인 연구가 부족한 실정이다. 본 연구에서는 다양한 타입으로 존재하는 과학기술분야 콘텐츠들을 대상으로 데이터 마이그레이션을 위한 모델을 설계하였고, 모델을 기반으로 실제 데이터 마이그레이션 작업을 수행한 결과를 제시하였다. 아울러 데이터 마이그레이션 결과에 대한 검증을 위해 데이터베이스의 완전성, 데이터값의 일관성, 관계의 일관성을 검증하였고, ANSI/ASQ Z1.4-2003에서 제시된 샘플링 검사 기법도 적용하였다. 결과적으로 모델 수립에 의한 체계적인 데이터 마이그레이션 수행은 데이터베이스 정합성 및 데이터값의 정확성에 영향을 미치고, 고품질의 데이터베이스를 유지하기 위한 필수 요소라 할 수 있다. The domestic market of database in Korea is estimated to be over 3.663 trillion won. The data migration is getting to be more important along with the continuous growth of the database industry. g-CRM and private recommending function are examples of the service that can be given through coupling among customer database, product database, geographic information database, and others. The core infrastructure is also the database which is integrated, perfect, and reliable. There are not enough researches on efficient way of data migration and integrating process and investigation of migrated data though trends of database in IT environment as above. In connection with this issue, we have made a model for data migration on scientific and technological contents and suggest the result of data migration process adapting that model. In addition, we verified migration's exhaustiveness, migration's consistency, and migration's coherence for investigation of migrated data and database. From the result, we conclude data migration based on proper model has a significant influence on the database consistency and the data values correctness and is essential to maintain high qualified database.

소음인(少陰人) 태음병(太陰病) 심하비증(心下?證)의 병증약리(病證藥理) 고찰

서영광,이지원,이준희,최원철,이의주,고병희,Seo, Young-Kwang,Lee, Ji-Won,Lee, Jun-Hee,Choi, Won-Cheol,Lee, Eui-Ju,Kho, Byung-Hee 사상체질의학회 2010 사상체질의학회지 Vol.22 No.3

1. Objective: Gastric Stuffiness (心下?證) in the Soeumin Taeeum symptomatology (少陰人 太陰病) in Sasang Constitutional Medicine shows an interesting evolutionary process. Originally found in the texts of Sanghanlun (傷寒論), the perspectives regarding the symptoms of Gastric Stuffiness were expanded by many medical scholars and Lee Jema. To comprehend the Jema's concept of Taeeum symptomatology and utilize his prescription clinically, it deserves to study on the Gastric Stuffiness in Donguisuseowon (東醫壽世保元). 2. Methods: Many texts including Sanghanlun (傷寒論) and Dongeuibogam (東醫寶鑑) were reviewed in order to track the evolutionary process concerning the symptoms of Gastric Stuffiness. Also, Lee Jema's works including the different versions of Donguisuseowon (東醫壽世保元) were reviewed to examine the development of Lee's concepts regarding the Gastric Stuffiness in the Soeumin Taeeum symptomatology. 3. Results and Conclusions: 1) Most of the previous concepts on Gastric Stuffiness were generally similar to those found in Sanghanlun, especially in that they addressed Yang deficiency of the middle triple energizeer as the central pathogenic process. 2) Lee Jema's views on the epigastric discomfort in the Soeumin Taeeum symptomatology evoloved over time and culminated in the finalized pathology and therapeutics appearing in his last work, the Shinchuk version of Donguisuseowon (東醫壽世保元). 3) 4 kinds of prescription which invented by Lee Jema to treat the Gastric Stuffiness in the Soeumin Taeeum symptomatology can be matched to the prescription of Sanghanlun respectively. However through evolutionary process of Jema's prescriptions, the indication of them expanded: not only to treat Gastric Stuffiness but to diverse symptoms of Soeumin.

자동착유시스템 설치농가의 설치 후 만족도에 관한 실태조사

기광석,김종형,정영훈,김윤호,박성재,김상범,이왕식,이현준,조원모,백광수,김현섭,권응기,김완영,여준모,Ki, Kwang-Seok,Kim, Jong-Hyeong,Jeong, Young-Hun,Kim, Yun-Ho,Park, Sung-Jai,Kim, Sang-Bum,Lee, Wang-Shik,Lee, Hyun-June,Cho, Won-Mo,Baek, Kwang- 한국축산환경학회 2011 축산시설환경학회지 Vol.17 No.1

본 시험은 국내에 도입되기 시작한 AMS에 대하여 설치 동기, 설치 후 우유생산량과우유품질, AMS 설치계기 및 설치 후 만족도, AMS 운영상 애로점 및 건의사항 등을 조사 분석하였다. 설치 계기가 무엇인가에 대한 응답비율은 노동력 부족 44%, 체험목장으로 전환 25%, 소들의 고능력화에 대응 19% 순이었으며 기타 6%였다. AMS 설치농가의 사육경력은 평균 24.9년, 평균 연령은 53.2세로 나타났으며 가족노동력만으로 경영하는 목장이 조사농가의 38%, 고용+자가노동력 형태의 목장이 63%로 나타났다. 목장의 산유능력은 두당 평균 유량은 1일 $30.9{\ell}$, 평균 유지율 3.9%, 세균수는 9.1천개/$m{\ell}$ 수준이었다. 후계자 육성에 대한 질문에 매우 그렇다라고 응답한 비율은 68%였으며, 보통 18%, 아니다와 매우 아니다라고 응답한 비율은 18%로 나타났다. 시스템 운영현황 및 애로사항을 파악하기 위하여 AMS의 프로그램 주운영자에 대한 질문에 본인 44%, 부인 6%, 자녀 또는 후계자사람이 44%, 기타 6%나 되었다. AMS 운영상 가장 어려운 점에 대한 조사결과, 기기 작동 및 복잡한 프로그램 운영이 각각 31%로 가장 많았다. 그 외 기계 에러 및 고장에 대한 애로사항이 25%이였다. 도태원인에 대하여 유방염 28%, 번식장애 20%, 발굽질환 19%, AMS에 부적합한 유두 배열 12%, 분만 후 대사성질병 7%, 노산 등 기타 14%였다. 시스템 설치 후 유지보수 계약 체결유무 및 비용에 대하여 유지보수 계약 56%, 유지 보수 계약 미체결 44%이었다. 유지보수 계약 평균 계약비용은 연간 658만원 정도였다. 시스템 설치 후 항목별 만족도에 대하여 5점 만점에 3.9점이었으며, 노동력 절감 3.7점, 업체의 A/S 3.6점, 산유량 증가 3.2점, 원유의 체세포 수 저감 2.8점이었다. 시스템 설치 시 고려사항 및 건의사항에 대하여 고가의 장비를 효율적으로 사용하기 위하여 젖소의 유방과 유두 배열이 적합하도록 젖소를 선발하는 것, 시스템을 운용할 수 있는 능력, 적합한 환경, 재정적 능력과 부지 확보, 지속적인 관찰 등이 권장되어야 할 것으로 나타났으며, 설치 업체에 대해서는 컨설팅이 체계화될 필요가 가장 높게 나타났으며 이어서 보다 저렴한 설치와 서비스의 체계화를 요구하는 결과를 보였다. The present survey was conducted to provide basic information on automatic milking system (AMS) in relation to purchase motive, milk yield and quality, customer satisfaction, difficulties of operation and customer suggestions, etc. Purchase motives of AMS were insufficient labor (44%), planning of dairy experience farm (25%), better performance of high yield cows (19%) and others (6%), respectively. Average cow performance after using AMS was 30.9l/d for milk yield, 3.9% for milk fat, 9,100/ml for bacterial counts. Sixty-eight percentage of respondents were very positive in response to AMS use for their successors but 18% were negative. The AMS operators were owner (44%), successor (44%), wife (6%) and company worker (6%), respectively. The most difficulty (31%) in using AMS was operating the system and complicated program manual. The rate of response to system error and breakdown was 25%. The reasons for culling cow after using AMS were mastitis (28%), reproduction failure (19%), incorrect teat placement (12%), metabolic disease (7%) and others (14%), respectively. Fifty-six percentages of the respondents made AMS maintenance contract and 44% did not. Average annual cost of the maintenance contract was 6,580,000 won. Average score for AMS satisfaction measurement (1 to 5 range) was 3.2 with decrease of labor cost 3.7, company A/S 3.6, increase of milk yield 3.2 and decrease of somatic cell count 2.8, respectively. Suggestions for the higher efficiency in using AMS were selecting cows with correct udder shape and teat placement, proper environment, capital and land, and attitude for continuous observation. Systematic consulting was highly required for AMS companies followed by low cost for AMS setup and systematization of A/S.

Magnetic Resonance Imaging Findings after Neoadjuvant Chemoradiotherapy Predict Prognosis Better than Magnetic Resonance Imaging Findings Before Neoadjuvant Chemoradiotherapy

Kwang-Seop Song,Dong Woon Lee,Bo Yun Hur,Min Ju Kim,Chang Won Hong,Sung Chan Park,Hyoung Chul Park,Dae Kyung Sohn,Byung Chang Kim,Kyung Su Han,Jae Hwan Oh 대한외과학회 2018 대한외과학회 학술대회 초록집 Vol.2018 No.11

HBV : PE-022 ; Hepatitis B surface antigen quantification across different phases of chronic hepatitis B virus infection using immunoradiometric assay

( Kwang Hyun Chung ),( Ho Young Lee ),( Yong Jin Jung ),( Hwi Young Kim ),( Ji Won Kim ),( Ji Bong Jeong ),( Byeong Gwan Kim ),( Kook Lae Lee ),( Won Kim ) 대한간학회 2012 춘·추계 학술대회 (KASL) Vol.2012 No.1

Background/Aim: Assays for hepatitis B surface antigen (HBsAg) quantification are emerging serologic tests which might determine treatment strategy and monitor treatment responses in chronic hepatitis B (CHB) patients. The aim of our study was to evaluate the dynamic changes in HBsAg titers during the natural course of CHB infection, and identify correlations between HBsAg titers and hepatitis B virus (HBV) DNA concentrations across different phases of CHB measured using novel immunoradiometric assay (IRMA). Methods: Serum HBsAg titers and paired HBV DNA concentrations in the different phases of CHB were retrospectively compared from August 2010 to March 2011 by correlation analysis. Phases of CHB were defined on the basis of HBV DNA concentrations, serum hepatitis B e antigen/ antibody status, and serum alanine aminotransferase levels. Additionally, mean HBsAg titers were compared across the different stages of chronic liver disease. Results: In 629 serum samples, mean HBsAg titers were significantly higher in the immune tolerance (ITO) and immune clearance (ICL) phases than in immune control (ICN) and immune escape (IES) phases. Correlations between HBsAg titers and HBV DNA concentrations varied with the CHB phases. Modest correlation was observed in ITO (n=54, r=0.733, p<0.001) and ICL (n=28, r=0.677, p<0.001), and poor correlation in ICN (n=79, r=0.242, p=0.032); however, no significant correlation was seen in IES (n=86, r=0.015, p= 0.894) and the oral nucleos(t)ide analogues-treated group (n= 252). Additionally, the mean HBsAg titers were significantly higher in patients with liver cirrhosis or hepatocellular carcinoma than in patient without liver cirrhosis or hepatocellular carcinoma (21574.7 vs. 4525.5 IU/mL, p<0.001; 16616.4 vs. 3529.6 IU/mL, p<0.001, repectively) and tended to gradually decrease as the 10-year age stratum increased (P for trend<0.001). Conclusions: HBsAg quantification using the IRMA method might be useful to discriminating patients in different phases of CHB and in different stages of chronic liver disease.

Expression of a Tomato Proteinase Inhibitor I Gene in Tobacco

Lee, Jong Seob,Ahn, Ji Hoon,Suh, Jeong Won,Lee, Kwang Woong 한국유전학회 1988 Genes & Genomics Vol.10 No.4

A wound-inducible proteinase inhibitor I gene was isolated from a genomic library and characterized at the nucleotide sequence level previously. In order to understand the molecular biology of wound induction of the inhibitor I gene, the inhibitor I-chloramphenicol acetyltransferase (CAT) chimaeric genes were constructed in a vector derived from Ti plasmid of Agrobacterium tumefaciens. One of the constructs, pJSL105 was introduced into tobacco cells by electroporation, which were regenerated into intact plants. Southern hybridization of genomic DNAs isolated from leaves of a transgenic plant revealed the presence of the plasmid DNA. Agrobacterium-mediated transformation of tobacco was also carried out with pJSL105. Leaf segments were co-cultivated with Agrobacterium containing pJSL105 mobilized from E. coli by triparental mating. Kanamycin-resistant colonies initiated at the boundary of leaf segments were regenerated into plants. The functionality of the wound-inducible promoter of the inhibitor I gene is being tested by CAT assay.

HBV : PE-022 ; Hepatitis B surface antigen quantification across different phases of chronic hepatitis B virus infection using immunoradiometric assay

( Kwang Hyun Chung ),( Ho Young Lee ),( Yong Jin Jung ),( Hwi Young Kim ),( Ji Won Kim ),( Ji Bong Jeong ),( Byeong Gwan Kim ),( Kook Lae Lee ),( Won Kim ) 대한간학회 2012 춘·추계 학술대회 (KASL) Vol.2012 No.-

Background/Aim: Assays for hepatitis B surface antigen (HBsAg) quantification are emerging serologic tests which might determine treatment strategy and monitor treatment responses in chronic hepatitis B (CHB) patients. The aim of our study was to evaluate the dynamic changes in HBsAg titers during the natural course of CHB infection, and identify correlations between HBsAg titers and hepatitis B virus (HBV) DNA concentrations across different phases of CHB measured using novel immunoradiometric assay (IRMA). Methods: Serum HBsAg titers and paired HBV DNA concentrations in the different phases of CHB were retrospectively compared from August 2010 to March 2011 by correlation analysis. Phases of CHB were defined on the basis of HBV DNA concentrations, serum hepatitis B e antigen/ antibody status, and serum alanine aminotransferase levels. Additionally, mean HBsAg titers were compared across the different stages of chronic liver disease. Results: In 629 serum samples, mean HBsAg titers were significantly higher in the immune tolerance (ITO) and immune clearance (ICL) phases than in immune control (ICN) and immune escape (IES) phases. Correlations between HBsAg titers and HBV DNA concentrations varied with the CHB phases. Modest correlation was observed in ITO (n=54, r=0.733, p<0.001) and ICL (n=28, r=0.677, p<0.001), and poor correlation in ICN (n=79, r=0.242, p=0.032); however, no significant correlation was seen in IES (n=86, r=0.015, p= 0.894) and the oral nucleos(t)ide analogues-treated group (n= 252). Additionally, the mean HBsAg titers were significantly higher in patients with liver cirrhosis or hepatocellular carcinoma than in patient without liver cirrhosis or hepatocellular carcinoma (21574.7 vs. 4525.5 IU/mL, p<0.001; 16616.4 vs. 3529.6 IU/mL, p<0.001, repectively) and tended to gradually decrease as the 10-year age stratum increased (P for trend<0.001). Conclusions: HBsAg quantification using the IRMA method might be useful to discriminating patients in different phases of CHB and in different stages of chronic liver disease.

The Imbalance between Coagulation and Fibrinolysis is Related to the Severity of the Illness and the Prognosis in Sepsis

(Kwang Joo Park),(Hyung Jung Kim),(Sung Chul Hwang),(Sun Min Lee),(Yi Hyeong Lee),(Myung Ho Hahn),(Sung Kyu Kim),(Won Young Lee) 대한내과학회 1999 The Korean Journal of Internal Medicine Vol.14 No.2

N/A Objectives:The coagulation and fibrinolytic system appears to be activated by the septic process independently, leading to the syndrome of disseminated intravascular coagulation(DIC). In this study, we investigated the changes within the hemostatic system related to the severity of the illness and the prognosis in patients with sepsis. Methods:Plasma thrombin-antithrombin III(TAT) and plasmin-α2-antiplasmin (PAP) complexes were measured using ELISA methods in 32 patients with sepsis and 20 controls and were analyzed according to the APACHE III scores and survival of the patients. Results:Plasma TAT and PAP in patients with sepsis were significantly higher than controls. Nonsurvivors showed greater levels of TAT(21.7 22.3ng/mL) and lower levels of PAP(628.4 378.1ng/mL) than survivors (TAT: 11.1 11.2ng/mL; PAP: 857.1 364.1ng/mL). The imbalance between coagulation and fibrinolysis described as TAT/PAP ratio was closely related with APACHE III scores in patients with sepsis(r=0.47) and the TAT/PAP ratio in nonsurvivors was significantly higher compared with survivors(34.4 21.4 vs. 14.4 13.8). Conclusion:In sepsis, both coagulation and the fibrinolysis system are activated and the imbalance between coagulation and fibrinolysis predisposes to the hypercoagulation state and is closely related to the severity of the disease and the prognosis.