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      • KCI등재후보

        브루셀라균에 노출된 미생물 검사실 직원들에 대한 예방적 항생제 요법과 혈청학적 추적검사

        이창섭,이혜수,이재현,박진희,최영실,황규잠,이흥범 대한감염학회 2008 감염과 화학요법 Vol.40 No.2

        The aerozolization is one of possible Brucella transmission mechanisms, particularly in air-borne exposed laboratory workers. In this study, seven laboratory workers were potentially exposed to B. abortus via aerosols. Two laboratory workers who sniffed an agar plate several times were considered to be at high risk for acquiring the disease, 5 workers who did not work directly with the strain were be considered at low risk of infection. Prophylactic antibiotics of doxycycline 200 mg/day and rifampin 600 mg/day were offered for 6 weeks in high risk workers and 3 weeks for low risk workers respectively. Enrolled workers were advised to check for serological testing of Brucella species every 3 weeks during a total period of 12 weeks. Compliance with taking medicine was 57.1% (4/7) and compliance for completing the serological tests was 85.7% (6/7). None of the laboratory workers developed clinical disease or tested positive serologically during 3 months of seroloaical testing and 1 year of clinical follow-up.

      • 노인의 영적 간호요구

        최미혜,김경희,김귀옥,김기숙,김수강,김정신,김춘숙,노흥진,박지연,성혜연,오명선,이선희,이원옥,이윤영,이현수,장명재,차혜경,채정선,홍상희 중앙대학교 의과대학 간호학과 간호과학연구소 2001 중앙간호논문집 Vol.5 No.1

        This study was designed to exam the aged's needs for spiritual nursing care. The purpose was to serve as a basis for the development of spiritual nursing practice. The major findings are as follows : 1. The degree of needs for spiritual nursing care as area was that needs of love and relationship mean 22.0, needs of meaning and object mean 28.2, needs of forgiving mean 13.5. Total needs for spiritual nursing care mean 63.7, which was on the upper middle level. The needs of meaning and object was rated highest. 2. Among the general characteristics of the subjects, needs of love and relatiohship wasn't significanlty different. 3. Among the general characteristics of the subjects, needs of meaning and object was significantly different according to two factors : age(F=7.260, p=0.001), religion(F=5.275, p=0.001). Higher needs of meaning and object was possessed by the older than the younger, by the one who have religion than the other. 4. Among the general characteristics of the subjects, four factors made a significantly difference to needs of forgiving : sex(t=-2.851, p=0.006), age(F=8.201, p=0.001), religion(F=6.928, p=0.000), disease(t=2.327, p=0.024). Higher needs of forgiving was possessed by man than woman, by the older than the younger, by the one who have religion than the other, by the one who have disease than the other.

      • 만성신부전에서 남성 Hormone 분비기능에 관한 연구

        이헌영,노흥규 충남대학교 의과대학 지역사회의학연구소 1986 충남의대잡지 Vol.13 No.1

        The serum prolactin, LH, FSH and testosterone were measured by RIA method for the evaluation of the hypothalamo-pituitary-testicular axis through the LHRH stimulation test before and after intramuscular injection of 50 mg of testosterone propionate(T.p.) in normal controls and patients with chronic renal failure (CRF) before specific treatment. 1. The basal level of the serum prolactin was significantly higher in the patients with CRF (124.9±46.3 ng/ml, M±S.E.) compared with normal controls(11.2±2.1 ng/ml). 2. The basal level of serum LH in normal controls was 7.1±1.4 mIU/ml and the peak level was 46.5±3.9 mIU/ml at 30 min. after iv injection of 100㎍ of LHRH. In patients with CRF, the basal serum level of LH was 15.5±2.7 mIU/ml and peak level was 37.1±5.4 mIU/ml at 180 min. after administration of LHRH, showing delayed response to LHRH stimulation in patients with CRF. After administration of T.p., the response of LH to LHRH stimulation in normal controls was suppressed, while in the patients with CRF, there was no significant difference between the responses before and after injection of T.p. 3. Basal serum FSH levels in normal controls was 3.2±0.4 mIU/ml, and at 60 min. after LHRH stimulation, level of the FSH was elevated to peak level significantly. The basal serum level of FSH in patients with CRF was 2.9±0.9 mIIU/ml and elevated more slowly with LHRH stimulation compared with normal controls. After injection of T.p., the basal levels of serum FSH and the responses to LHRH stimulation were not changed significantly in normal controls and the patients with CRF. 4. The basal serum level of testosterone was 5.2±0.4 ng/dl in normal controls. In the patients with CRF, the basal level of testosterone was significantly lower(3.5±0.8 ng/ dl) than that of normal controls. The serum testosterone level was not changed within 3 hours with LHRH stimulation in both normal controls and patients with CRF. After administration of T.p., the basal levels of testosterone in patients and controls were elevated significantly but there was no response to LHRH stimulation. With the above results, it can be concluded that the abnormal response of the pituitary gland to the change of testosterone level, elevated serum prolactin level, increased LH level, and abnormal response to LHRH stimulation contribute to the abnormal sexual functions in patients with CRF.

      • KCI등재

        치아 이상의 발생 빈도와 양상에 관한 연구

        이제호,손홍규,전승준,최형준 大韓小兒齒科學會 1996 大韓小兒齒科學會誌 Vol.23 No.2

        An object definition of the anomaly is not avaliable and most investigators define the term differently or fail to describe their criterion.Because dental anomaly may lead to many complications,early detection and diagnosis of dental anomalies are essential steps in the evaluation of the child patient and in treatment planning.These procedures require detailed medical and dental histories,through clinical examination and the use of radiographs.So,this study was designed to find out the prevalece of dental anomalies.The clinical and roentgenographic examination was undertaken for 8,054 children at age from 0 to 15 years and statistical analysis was done.The results were as follows: 1.Among the examined subjects 2,134 subjects(26.5%) showed dental anomalies.The prevalance of individure dental anomalies were as as follows:Supernumerary teeth 15.6% congenitally missing teeth 6.6%,fusion 2.2%,odontoma 0.35%,microdontia 1.2%,macrodotia 0.05%,gemination 0.22%,talon cusp 0.36%,dens evaginatus 0.24%,dens invaginatus 0.15%,dilaceration 0.27%,taurodontism 0.09%,abnormal tooth position 1.7%,natal $ neonatal teeth 0.92%,amelogenesis imperfecta 0.01%. 2.Significant correlations between the groups with individual dental anomalies were as follows:between groupⅠand other groups,there was nagative correlation,especially groupⅠ and groupⅡ.And the correlation coefficient between male and female showed differences. 3.For the supernumerary teeth group,the prevalence of male was higher than female(p<0.001).While for the congenitally missing teeth,macrodontia,microdontia,abnormal tooth position group,the prevalence of female was greater than male(p<0.001). 4.For the congenitally missing teeth group,the mandibular primary lateral incisor showed the highet incidence in primary dentition,while mandibular lateral incisor in permanent dentition.In the mandible(72.5%),this site showed higher prevelence than in maxilla.In this case with deciduous congenitally missing teeth,the prevelence of successive permanent congenitally missing teeth was about 33.9%,the incidence was highet in mandibular lateral incisors. 5.Most supernumerary teeth existed on middle area and showed inverted position and unerupted state.In addition,supernumerary teeth showed higher incidence on maxilla(99.3%). 6.In the case with deciduous fused teeth,the prevelence of successive permanent congenitally missing teeth was 39.9%,while that of successive permanent fused teeth was 2.7%.And the highet rate of the prevalence(40.3%) appeared in fusion of mandibular deciduous lateral incisor and canine. 7.In the case of odontoma,the prevelence was higher in maxilla(78.6%) and anterior region(82.7%) the mandible and posterior region.

      • KCI등재

        수종 치과재료의 제I급 와동에서의 변연 누출에 관한 실험적 연구

        이선희,손흥규,최형준 大韓小兒齒科學會 1996 大韓小兒齒科學會誌 Vol.23 No.1

        Microleakage is a problem of all filling materials of losted teeth structure and is clinically undetectable. Because marginal leakage may be responsible for pulp irritation, pulp inflammation, necrosis and recurrent caries, it is essential to prevent and control it. For the evaluations of microleakage of various class I filling materials, 175 extracted teeth were filled with amalgam, light curing composite resin, glass inomer cement, IRM and Fermit-N. After thermocycling, speciemens were placed in 1% methylene blue dye solution for 24 hours in an incubator set 37℃. The teeth were sectioned at filling body center and margin and degree of dye penetration was observed with a stereomicroscope. The following results were obtained. 1. Light cured composite resin has the excellent results and microleakage is increased in the order of amalgam, IRM, Fermit-N, glass ionomer cement.(SAS-6.0 system) and there was a statistically significancy in marginal leakage for each filling materials.(Kruskal-Wallis analysis, P<0.05) 2. Microleakage of the center and margin was statistically insignificant (Mann-Whitney analysis P<0.05) 3. There was less microleakage for amalgam than light cured composite resin but was statistically insignificant (Mann-Whitney analysis, P<0.05) and also showed less marginal leakage for Fermit-N compared to glass ionomer cement but also was statistically insignificant. (Mann-Whitney analysis, P<0.05).

      • KCI등재

        전위 배복된 상악 측절치와 상악 견치의 치험례

        이기영,최형준,손홍규 大韓小兒齒科學會 1999 大韓小兒齒科學會誌 Vol.26 No.4

        치아의 전위는 매우 드문 치아 기형의 하나로서 발생 또는 맹출중 인접한 2개의 영구치의 위치가 서로 바뀐것을 말한다. 전위는 상악과 하악 모두에서 발생 가능한데 그중에서 상악에서의 발생이 더 흔하며 상악견치는 가장 호발하는 치아이다. 상악에서는 상악 견치와 제 1 소구치와의 전위가 가장 빈도 높고 그 다음으로 상악 견치와 측절치와의 전위가 많다. 전위는 완전 전위와 불완전 전위로 나눌수 있는데 완전 전위는 치관뿐 아니라 치근의 위치까지 전위된 경우를 말하고 불완전 전위는 치근의 위치는 정상이고 치관만 전위된 경우이다. 전위의 원인에 대하여 명확하게 밝혀진 것은 없으나 유치의 만기잔존이나 조기상실, 발생중의 전위나 정상 맹출 경로로부터의 이탈, 유치열시기의 안면외상 등이 제기되고 있고 이밖에 과잉치, odontoma 또는 odontogenic cyst, 염증성 병소 등을 그 원인으로 생각해 볼 수 있다. 본 증례는 유치열시기의 안면외상으로 인하여 상악 영구 견치와 측절치의 전위가 발생한 경우로서 치료후 전위된 위치로의 양호한 배열을 이루었다. Transposition has been described as an interchange of position of permanent tooth and is relatively rare dental anomaly. Transposition of teeth may occur both in the maxillary and mandibular arches. but it appears more often in the maxilla of individual teeth, the maxilla canine is the most often involved. A canine transposes most often with a first premolar and less frequently transposes with a lateral incisor. Incomplete transposition is a condition describing an interchange in the position of the crowns of two permanent teeth, while the root apices remain in their relative position. Complete transposition is a situation in which both the crowns and entire root structure are transposed. The etiologic factors of transposition are tooth buds interchange, retained deciduous canines, migration of the erupting canine, trauma to deciduous teeth etc. This report describes a case of a transposition between a maxillary left canine and a lateral incisor and impaction of a maxillary left central incisor due to trauma to deciduous dentition.

      • 괴사후성과 비괴사후성 간경변증에서 원인별 주석교질 (^99mTc-tin colloid) 간스캔의 차이

        이헌영,허승식,이강욱,정현용,김삼용,신영태,김영건,노흥규 충남대학교 의과대학 지역사회의학연구소 1992 충남의대잡지 Vol.19 No.2

        The differences of the liver scintigraphic features between postnecrotic and nonpostnecrotic liver cirrhosis were studied for 69 patients. Degrees of mottling and splenomegaly were no different between two groups but shrinked form was more frequent finding in postnecrotic type(23:10), and normal shape & enlarged left lobe with shrinked right lobe were relatively dominant in non-postnecrotic group(15:6, 10:2). Grade of extrahepatic uptake of ^99mTc-tin colloid was significantly higher in Child-Pugh B & C group than A group(p<0.05), but there was no difference between postnecrotic and non-postnecrotic groups. These will be important results on the dicision for the presence of cirrhosis according to the variable causes.

      • KCI등재

        육군 범법자들에 대한 정신의학적 특성 분석

        이규환,박흥수,이정태 大韓神經精神醫學會 1989 신경정신의학 Vol.28 No.2

        The authors compared two hundred forty-eight imprisoned soldiers with two hundred seventy-nine normal controls using MMPl and Ego-Strength Scale in R.0.K. Army. The results were as follows ; 1) Mean age of imprisoned soldiers was 23.4, while that of controls was 23.9. 2) Educational level of imprisoned soldiers was lower than that of normal controls. 3) Pre-enlistment occupations in imprisoned soldiers chiefly were employees and factory workers (39.9%), while students consisted of 54.4% in normal controls. 4) More than half(61.4%) of the criminal acts had occured during the first year of the military service 5) Of the various criminal acts, absence without leave was the most frequent criminal activities(50.6%). 6) The result of MMPI was significantly different between two groups except L subscale. More specifically, F, Ma, Sc, Pd, Pa subscales which indicate a tendency of behavioral acting out were high in imprisoned soldiers, but all subscales showed below scores of 65. 7) Scores of Ego-Strength Scale in imprisoned soldiers were lower than that of the controls.

      • 11세 여아에서 발생된 성숙 낭성 기형종의 염종1예

        이희민,김재현,이봉주,하태규,김흥곤,윤기중 圓光大學校 醫科學硏究所 1996 圓光醫科學 Vol.12 No.1

        Mature cystic teratomas comprise 10% of all ovarian tumors and show the highest frequency of incidence in women under 20 years of age. Torsion of ovarian cyst is the most common complication in young female and lower abdominal pain, peritonitis, necrosis and shock are outcomes that require emergency treatment. Generally, gross finding of mature cystic teratoma shows that most of the entire ovary is replaced by multiple cystic masses, and rarely only small portion of the ovary is changed into cystic mass. We report a case of torsion of mature cystic teratoma in an 11 year old girl with a brief review of literature.

      • KCI등재

        구호흡을 동반한 증식성 치은염 환자의 치료증례

        이종갑,이남형,손흥규,김형태 大韓小兒齒科學會 1993 大韓小兒齒科學會誌 Vol.20 No.2

        Mouth breathing gives direct irritation to gingival tissue and increases gingivitis by increasing debris deposite. Generally, it is reported that gingivitis increases at puberty and it is mainly caused by microbial change and hormonal imbalance. This study included generalized gingivitis accompanying mouth breathing and localized gingival hypertrophy. This 11 years old female patient had no past medical history but she had menarchy a year ago. As a treatment, primarily eliminated the cause of mouth breathing and conducted tooth brushing instruction, scaling, and gingivectomy which resulted good.

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