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      • KCI등재

        토양중 게르마늄 농도에 따른 벼의 생육 특성 및 게르마늄 흡수

        이성태,이영한,최용조,이상대,이춘희,허종수 한국환경농학회 2005 한국환경농학회지 Vol.24 No.1

        게르마늄의 약리효능이 알려짐에 따라 게르마늄이 깅화된 기능성 농산물의 요구도가 높아지는 추세이다. 본 연구는 게르마늄의 농업적 이용에 대한 기초 사료를 제공하고자 실시하였으며, 벼의 생육 및 게르마늄 흡수에 미치는 게르마늄처리 효과는 다음과 같다. 게르마늄을 0, 2.5, 5.0, 7.5 및 10.0 mg/kg으로 처리할 토양을 와그너포트에 넣어 벼를 재배힌 결과, 게르마늄 처리농도가 증가할수록 게르마늄 독성의 증가로 초장, 수장, 수수 및 수량이 급격히 감소하였으며 게르마늄 2.5 mg/kg 이상에서는 게르마늄 독성이 발생하였다. 게르마늄 처리농도가 증가할수록 벼의 게르마늄 흡수랑은 증가하였으나 벼의 게르마늄 이용율은 게르마늄 2.5, 5.0, 7.5 mg/kg 처리에서 각각 20.7, 12.5 및 7.5%로서 게르마늄 처리농도가 증가할수록 감소하였다. 벼의 부위별 게르마늄 함량은 볏짚>왕겨>현미 순으로 높았다. 게르마늄 2.5 mg/kg 처리시 볏짚, 왕겨 및 현미의 게르마늄 함량은 각각 103.4, 30.2 및 3.02 mg/kg 이었고, 볏짚과 왕겨에서는 게르마늄 무처리에서도 각각 2.9 및 3.9 mg/kg을 함유하고 있었다. 쌀의 아미노산 함량을 분석한 결과 게르마늄 처리농도가 증가할수록 Asx., Thr., Ser. 등 대부분 종류의 아미노산 함량이 증가하였으며, 그 결과 현미중 질소흡수량도 증가하였다. In order to obtain the basic information for agricultural utilization of Germanium(Ge), the growth characteristics and Ge absorption of rice plant were investigated with different Ge concentration in soil. Ge concentrations were treated with 0, 2.5, 5.0 7.5 and 10.0 mg/kg in pot(1/5,000a), respectively. As higher the Ge concentration in soil, the Ge absorption amount in straw, husk and brown rice were increased. But the yields were decreased with the increase of Ge phytotoxicity. When rice plant was grown more than 2.5 mg/kg Ge(as GeO₂) in the soil, growth was inhibited by germanium phytotoxicity and necrosis spots were observed in the rice leaf blades. Therefore the optimum concentration of Ge was less than 2.5 mg/kg in rice plant. When rice plant was cultivated on soil supplemented with 2.5 mg/kg Ge, Ge content in straw, husk and brown rice was 103.4, 30.2 and 3.02 mg/kg, respectively. The Ge content in plant was high in the order of straw > husk > brown rice. Most of the amino acids in rice were increased with the increase of Ge treatment, besides, total amino acid contents also increased.

      • SCOPUS

        Firmware Design for Portable PCR Devices Controlled by Smart Phones through Wireless Communication

        Wan Yeon Lee1,Min Ja Kim,YoungWoong Ko,Jong Dae Kim 보안공학연구지원센터 2014 International Journal of Control and Automation Vol.7 No.11

        In this paper, we design and implement a firmware for portable PCR devices that is controlled by a smart phone. The firmware has the host-local structure in which the firmware receives operation commands from the smart phone and sends operation results to the smart phone through Bluetooth communication. The firmware is designed to accommodate unstable wireless communication of Bluetooth. We implement a low-cost small PCR device with the proposed firmware on microchip PIC18F4550, and verify that the implemented PCR device significantly re

      • 아연계 탈황제의 장기연속 반응성 연구

        박노국,이종욱,이승철,이종대,류시옥,이태진 영남대학교 공업기술연구소 2000 工業技術硏究所論文集 Vol.28 No.2

        The zinc titanate sorbents(ZTG40) were prepared and the tests for durability and attrition resistance were carried out to develop the highly effective desulfurization sorbents. In the attrition tests for ZTG40 the results showed that the attrition resistance was 94.08% and that the sulfur capacity was maintained above 15g S/100g sorbent throughout the 100-cycle test, its maximum being 23.05g S/100g sorbent. As compared to sorbents developed by the developed countries, ZTG40 showed superior performances. In the advanced countries 15g S/100g sorbent is a yardstick of excellency for the sulfur capacity of desulfurization sorbents. Therefore, ZTG40 developed in this study has the desirable physical and chemical properties for fluidized desulfurization of coal gases.

      • KCI등재후보

        Toluene, Xylene, Trichloroethylene 투여가 흰쥐의 시상하부와 뇌하수체의 GnRH, GnRH Receptor, Pit-1 유전자 발현에 미치는 영향

        기노석,이종태,강대성,김대환,이채관,이헌,전진호,김정호,이채언 大韓産業醫學會 1998 대한직업환경의학회지 Vol.10 No.2

        The workplace exposure of chemicals has steadily increased, therefore the concern for subsequent effect on reproductive outcome has been an important issue in occupational medicine. In previous studies, higher rates of spontaneous abortion, reduced fertility and menstrual disorder among women, and an impairement of sperm quantity and quality among men have been associated with a wide variety of chemical agents. This study was conducted to evaluate the effects of toluene, xylene and trichloroethylene(TCE) injection on the mRNA levels of GnRH, GnRH receptor and Pit-1 genes in male rats hypothalamus and pituitary and the effects on the plasma levels of FSH, LH, prolactin and testosterone. Sprague-Dawley male rats were divided into five groups of five each according to concentration of toluene, xylene and TCE. The rats were injected subcutaneously to 0, 50, 100, 200, 400 mg/kg body weight/day of toluene, xylene and TCE, respectively for 6 days. Rat brains were excised and hypothalamus and pituitary were separated. Reverse transcription-polymerase chain reaction (RT-PCR) and RNase protection assay(RPA) were used to evaluate the GnRH, GnRH receptor and Pit-1 mRNA levels. Plasma concentrations of FSH, LH, prolactin and testosterone were assayed by radioimmunoassay(RIA). The results were as follows; 1. GnRH, GnRH receptor and Pit-1 mRNA levels in toluene and xylene injected groups, and GnRH receptor mRNA levels in TCE injected group were lowered dose-dependently. Especially, GnRH receptor and Pit-1 mRNA levels in 200mg/kg of toluene injected group, and GnRH, GnRH receptor and Pit-1 mRNA levels in 400mg/kg of toluene injected group were significantly lower than control group (p<0.05). GnRH receptor and Pit-1 mRNA levels in 400mg/kg of xylene injected group, and GnRH receptor mRNA levels in 400mg/kg of TCE injected group were significantly lower than control group(p<0.05). 2. The plasma levels of prolactin and testosterone in 400mg/kg of toluene injected group, and LH in 100, 200 and 400mg/kg of xylene injected group, and testosterone in 400 mg/kg of TCE injected group were significantly lower than control group(p<0.05). In conclusion, we speculated that toluene and xylene affected reproductive system secondarily through hypothalamus-pituitary axis, and TCE affected directly through steroidogenesis. And we recommended that further study for assessment of the reproductive toxicity of mixed organic solvent exposures should be conducted.

      • KCI등재후보

        Discordance in Spirometric Interpretations Based on Korean and Non-Korean Reference Equations

        Nami Kim,Mi-Hee Park,Se-yeong Kim,Chunhui Suh,Sangyoon Lee,Kun-Hyung Kim,Chae-Kwan Lee,Dae-Hwan Kim,Jong-Tae Lee 대한직업환경의학회 2013 대한직업환경의학회지 Vol.25 No.-

        Objectives: Korean regression models for spirometric reference values are different from those of other ethnic groups. The purpose of this study was to evaluate discordance in spirometric interpretations based on using Korean reference equations versus non-Korean reference equations. Methods: Spirometry was performed on 825 Korean male workers from April 2009 to November 2011. The spirometric patterns and disease severity were evaluated using two Korean equations (Choi’s and Lee’s) and three equations for Caucasians (NHANES III, Morris’s, and Knudson’s), and the results of Choi’s equation were compared with the non-Korean equations. The spirometric patterns were defined as normal, restrictive, and mild and moderate obstructive. Results: The mean differences in the FEV1% and FVC% between the two Korean equations were 2.0 ± 1.3% and 3.5 ± 2.2%, respectively. Morris’s equation had the greatest difference in the FEV1% from Choi’s equation: 32.9 ± 8.5%. Knudson’s equation had the greatest difference in the FVC% from Choi’s equation: 10.5 ± 6.5%. Conclusions: The two Korean equations shared similar characteristics of spirometric interpretation. The spirometric interpretations of Choi’s equation were significantly different from those of Morris’s equation and Knudson’s equation.

      • SCOPUSKCI등재
      • 두경부 종양세포주에 대한 Mithramycin A의 세포자멸사 유도성 및Cisplatin 항암작용 증가효과

        이강대,손성환,박종욱,김영록,이봉주,김주연 고신대학교의과대학 2008 고신대학교 의과대학 학술지 Vol.23 No.1

        Background and Objectives : Cisplatin (CP) is a major chemotherapeutic agent for head and neck cancer. However, cancer cells can get drug resistance through recovering the DNA damage by CP. Mithramycin A (MA) can inhibit gene expression of multidrug resistance gene 1, c-myc or h-ras. The goal of this study is to evaluate the therapeutic effect of MA alone and combination of MA and CP on head and neck cancer cell lines. Materials and Methods : Two head and neck cancer cell lines (AMC-HN4, AMC-HN7) were treated with MA. The cellular proliferation, apoptosis and protein expression were measured with XTT assay, FACS analysis, and western blotting, respectively after MA treatment in cell lines. In order to know the combination effect of MA with CP, the cancer cell lines were treated with MA, CP, and MA/CP combination, and cellular proliferation, apoptosis and expression of apoptosis-associated proteins were measured. Results : MA inhibited the proliferation of head and neck cancer cells and induce dapoptosis. Increase of caspase activation, PLC-?1 fragmentation and percent apoptosis by MA treatment was blocked by z-VAD-fms, but not blocked by N-Acetyl Cystein. Combination of MA and CP significantly inhibited cancer cell growth and increased apoptosis compared to MA and CP alone, and it also suppressed the expression of anti-apoptotic proteins such as XIAP and Mcl-1. Conclusions : The present study suggests that MA alone andMA/CP combination chemotherapy could be a potential regiment for the control of the head and neck cancer.

      • 나팔형 방파호안의 월파저지성능에 관한 실험적 연구

        이성대,박종배 한라대학교 2006 論文集 Vol.9 No.-

        A new type of shore protection with a deep re-curved parapet, called a flare-shaped seawall(FSS), was developed We have carried out the experiment to examine the hydrauic performance of the FSS and the conventinal seawall for bottom slope of 1/10 in a piston type wave flume Wave overtopping prevention was found to depend mainly on the specific volume between the front of the shore protection and the water surface It has proven that FSS, compared with conventional seawalls, decrease wave overtopping Consequently, FSS was found to be effective to reduce wave reflection coefficient, stability of structure and consistently prevent wave overtopping

      • 『辨證奇聞』의 醫學的 特徵에 關한 考察 : 傷寒門을 중심으로 In view of ShangHan

        이원석,박선동,박원환,김준기,김종대 동국대학교 한의학연구소 1998 東國韓醫學硏究所論文集 Vol.6 No.2

        『辯證奇聞』은 淸代(1687年) 陳土鐸이 著述한 醫書로서 126門의 형식으로 이루어져 있다. 내용을 보면 한의학적 理法方藥의 논리체계를 제시하였다고 볼 수 있다. 明末淸初이후 중국에서는 實證的인 學風의 등장에 따라 歷史理論에 대한 비판 및 정리작업이 활발히 이루어지기 시작하였으며, 이 시기에 저작된 『辯證奇聞』은 현재 우리나라 臨床家에서 널리 膾炙되고 있는 秘方과 관련된 醫書중의 하나로 이에 대한 내용을 정리함으로서 현대와의 연계를 도모해 볼 수 있었다. 주로 腑臟辯證論治에 대한 시각에 입각하였고, 「傷寒論」을 보완하면서 비판한면도 찾아볼 수 있었다. 약물은 體內의 津液損傷與否를 살펴 사용하였다. In order to find the characteristic medical mothods of 『BianZhengGiMun』by the author ChenshiTo, we have translated and analyzed the mentioned book. Upon analyses, the following facts were noted: 1) 『BianZhengGiMun』is written and composed of case studies. Prescriptive methods described here differ rather from previously known methods, where as our nation's Oriental medicine practioners refer and consider these methods as miraculous modern methodologies. 2) Book's content has much similarities to 『ShangHanLun』's original text. Moreover, the content is adjusted towards presenting methodologies not covered in 『ShangHanLun』's text, together with adding more information to converse 『ShangHanLun』's methods as well as to critique them. 3) Diagnostic methods mainly follow the ZangFuBianZheng(朧腑辨證)'s pattern, where it's recorded information and theories are valid. 4) 『BianZhengGiMun』's prescriptive methods usually follow BuYinShengJin(補陰生津)'s form, where they were appropriate for that period and circumstances. 5) In consideration of all of the above factors, ChenShihTo grasped ShangHan and WenBing(acute febrile disease due to exogenous factor) as WaiGanReBing(外感熱病)'s double sided characteristics, where this corresponds with the current belief. It is believd that this in turn would provide much practical value to the present time.

      • 高蛋白 熱帶荳科植物 Winged bean의 適應栽培에 關한 硏究 : 栽植密度에 따른 試驗 on the planting density

        李宗玉,徐大振 진주산업대학교 1982 論文集 Vol.20 No.-

        熟帶産 高蚤白 資源植物인 Winged bean(UPS-63)의 栽植密度에 따른 栽培適應性을 檢討하기 위하여 試驗한 結果를 要約하면 다음과 같다. 1. 支柱架設을 하며 栽培할 때는 栽植密度 75×30cm區가 總莢數 및 總收量이 가장 많았다. 2. 볏짚 被覆을 하여 栽培할 때는 栽植密度 75×45cm區가 總莢數 및 總收量이 가장 많았다. 3. 栽植密度에 따라서 開花始와 蔓長은 큰 差異가 없었다. 4. 株當莢數 및 莢當粒數는 栽植密度가 낮을수록 높은 成績을 나타냈다. The aim of the present experiment is to test the planting adaptability according to the different planting density for the high protein tropical plant, the winged bean (UPS-63). This results obtained in this experiment were as follows: 1. Total pods and total yield of the 75×30cm planting density plot were in building of the bamboo plot were observed the most. 2. Total and total yield of the 75×45cm planting density plot in the straw mulching plot were shown the most. 3. The first flowering day and the plant length according to planting density were shown little. 4. The lower the planting density was, The more the pods hill and grains per pod were.

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