http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Autonomous Access to the Moon for Europe: The European Large Logistic Lander
Markus Landgraf,Ludovic Duvet,Alexander Cropp,Gustavo Alvarez,Grzegorz Ambroszkiewicz,Massimiliano Bottacini,Pierre Brunner,Lorenzo Bucci,William Carey,Andrea Emanuele Maria Casini,Giorgio Cifani,Oliv 한국항공우주학회 2022 한국항공우주학회 학술발표회 논문집 Vol.2022 No.11
Steffen Landgraf,Anastasiya Ilinykh,Chiara S. Haller,Olga Shemelina,David Cropley,Isabella von Treskow,Olga M. Razumnikova,Tanja Kutscher,Elke van der Meer 대한사고개발학회 2015 The International Journal of Creativity & Problem Vol.25 No.1
This study investigates the impact of cultural background on creativity and schizotypy. Verbal and figural creativity, as well as schizotypal personality traits were assessed in 45 German and 46 Russian individuals. First, while Russian women scored higher on creative abilities than German women, German men scored higher than Russian men. Second, Germans compared to Russians showed higher “innovative capacities”, that is, product-oriented creativity. Third, ‘negative’ schizotypy predicted “innovative capacities”, and this effect was mediated by culture. These results suggest that the construct validity of creativity and schizotypy, as well as their association may be culture-specific. Thus, cultural backgrounds may contribute to labeling behavior as socially acceptable, e.g., creative, or psychopathological, e.g., schizotypal.
Adriano Cressoni Araujo,Elen Landgraf Guiguer,Sandra Maria Barbalho,Patricia C. S. Bueno,Juliana Agostinho Lopes,Bruna Ferreira da Silva,Letı´cia Cabrini Girotto,Marina Guirro de Paula,Paulo Vitor Zeb 한국식품영양과학회 2016 Journal of medicinal food Vol.19 No.1
Joannesia princeps is a plant commonly used in folk medicine as laxative for menstrual discomfort and as antihelminthic and antimicrobial to reduce edema and improve tissue healing. The seeds are used in many regions of Brazil as laxative; however, studies are needed to confirm its effectiveness and safety. Thus, the aim of this study was to evaluate the effects of using seeds of this plant on intestinal motility of Wistar rats, evaluate the effects and acute toxicity of its management, as well as determine its phytochemical profile. The evaluation of the effect on the intestinal motility was performed according to the model described by Michelin and Salgado (2004) with modifications. For the evaluation of acute toxicity, we used the model described by Craveiro et al. (2008) and Goloni et al. (2005), and for the analysis of the presence of alkaloids, flavonoids, anthraquinones, steroids, and other components, we used the method described by Carvalho et al. (2006). The results showed that J. princeps exhibits laxative effects similar to those of Senna species such as Cassia angustifolia and the phytochemical analysis of ethanol and aqueous extracts showed the presence of alkaloids, triterpenes, and/or steroids compounds. Acute toxicity showed in the first 12 h: piloerection, contortion, decreased respiratory rate, diarrhea, and weight loss. After this period, these changes were no longer observed. It was concluded that the seeds of this plant have potential laxative activity, confirming the popular use and that the dose of 5 g/kg can be considered safe for consumption.
Viscosity dependence of rubrene fluorescence quenching by organic radicals via energy transfer
Grampp, Gunter,Justinek, Martin,Landgraf, Stephan,Angulo, Gonzalo,Lukzen, Nikita Korean Society of Photoscience 2009 Photochemical & photobiological sciences Vol.8 No.11
The kinetics of rubrene (5,6,11,12-tetraphenylnaphthacene) fluorescence quenching by energy transfer to the radicals of N,N,N',N'-tetramethyl-para-phenylenediamine ($TMPD^{+\cdot}$), tetracyanoquinonedimethane ($TCNQ^{-\cdot}$) and galvinoxyl (2,6-di-tert-butyl-alpha-(3,5-di-tert-butyl-4-oxo-2,5-cyclohexadien-1-ylidene)-p-tolyloxy; $GAL^{\cdot}$), have been measured in solvents of different viscosities. At room temperature the observed quenching rate constants vary between 0.12 and $7.8{\time}10^{10}M^{-1}s^{-1}$, always exceeding the diffusion rate constants given by the simplest version of Smoluchowski theory combined with the rate constants for dipole.dipole energy transfer. This discrepancy is explained by accounting for the non-stationary stage in the F$\ddot{o}$orster kinetics, even though the experimental fluorescence decays are apparently mono-exponential.
Pereskia aculeata Miller Flour: Metabolic Effects and Composition
Sandra Maria Barbalho,Elen Landgraf Guiguer,Paulo Sergio Marinelli,Patrı´cia Cincotto do Santos Bueno,Leticia Maria Pescinini-Salzedas,Mirele Cristine Batista dos Santos,Marie Oshiiwa,Claudemir Gregor 한국식품영양과학회 2016 Journal of medicinal food Vol.19 No.9
Pereskia aculeata Miller is known in Brazil as ora-pro-nobis (OPN) and has been used commonly in the folklore medicine. The purpose of our study was to evaluate the composition and the effects of OPN flour on the metabolic profile and intestinal motility of Wistar rats. Animals were divided randomly into five groups (n = 10): G1 (control group) and G2 (treated with OPN flour). For the intestinal motility: G3 (control group), G4 (treated with senne), and G5 (treated with OPN flour). After 40 days, G1 and G2 were euthanized and metabolic profiles were analyzed (glycemia, cholesterol, triglycerides, high density lipoprotein [HDL-c], C reactive protein, AST, ALT, Lee Index, weight, and visceral fat). The flour of OPN was effective in reducing percentage of weight gain, visceral fat, levels of total cholesterol, triglycerides, low density lipoprotein, very low density lipoprotein, and increased HDL-c. Significance was also found in the distance covered by the activated charcoal from the pylorus to the beginning of the cecum, which was higher in animals treated with OPN. Our results indicate that OPN flour may bring health benefits, as the improvement of the intestinal motility, and it is associated with reduction of visceral fat and lipid profile, as well as the increase of HDL-c levels. With these results, we may suggest that the incorporation of this flour in different industrial products may be a convenient and effective way for the intake of healthier products.
Patricia Cincotto dos Santos Bueno,Sandra Maria Barbalho,Elen Landgraf Guiguer,Maricelma da Silva Soares de Souza,Isabela Ramos Arau´jo de Medeiros,Isabella Vasconcelos Zattiti,Manuela dos Santos Buen 한국식품영양과학회 2019 Journal of medicinal food Vol.22 No.12
Studies have shown that the consumption of a diet containing whole grains may improve metabolic homeostasis and is related to the reduction of risk factors for the development of obesity, diabetes, cardiovascular diseases, and cancer. We aimed to investigate the effects of Triticum aestivum and Triticum turgidum on the metabolic profile of Wistar rats. Animals were divided into G1 (control group), G2 (T. turgidum), and G3 (T. aestivum). Anthropometric and biochemical parameters were evaluated after 45 days of treatment with both types of wheat. Our results showed that the use of the common or green wheat improved body weight percentage, visceral fat, glycemia, low-density lipoprotein cholesterol, triglycerides, and atherogenic indices such as atherogenic index, CCR1, and CCR2. Furthermore, wheat may also improve high-density lipoprotein cholesterol levels. The health-promoting properties of wheat occur probably due to the content of phytochemicals, antioxidants, and fibers. We suggest that the intake of T. aestivum and T. turgidum may be helpful in the prevention or treatment of obesity, diabetes and cardiovascular diseases.
Henrique Bosso,Giovanna Emanuella Piffer Soares Arantes,Sandra Maria Barbalho,Elen Landgraf Guiguer,Maricelma da Silva Soares de Souza,Patrıcia Cincotto dos Santos Bueno,Agnaldo Bruno Chies,Priscilla 한국식품영양과학회 2019 Journal of medicinal food Vol.22 No.4
Many studies have shown that plants can be therapeutic alternatives in the prevention or treatment of various diseases. Among these, green coffee may present different pharmacological effects related to the regulation of glycemia and lipid metabolism and is related to the prevention of cardiovascular diseases. The objective of our study was to evaluate the effects of using green and ripe coffee on the metabolic profile and muscular enzymes after the practice of physical exercises in Wistar rats. We included six groups: G1 (control group), G2 (group submitted to swimming), G3 (group that consumed green coffee), G4 (group that consumed green coffee and was submitted to swimming), G5 (group that consumed ripe coffee), and G6 (group that consumed ripe coffee and was submitted to swimming). Our results showed that there was a significant reduction in the percentage of visceral fat in G3, G5, and G6. We did not observe significant modifications in glycemia, lipids, lactate dehydrogenase, ferric reducing ability of plasma, and ferric-xylenol orange. The levels of creatine phosphokinase showed a reduction in the groups G2 and G4. No significant differences were found in the atherogenic indices. There is a global demand for natural compounds that can be safe, cheap, related to minimum side effects, and provide health benefits. Our results show that the use of green or ripe coffee may contribute to reduce the percentage of visceral fat and consequently may protect against further complications once this tissue produces proatherogenic hormones. Furthermore, green coffee may play a role in protecting muscle injury after the practice of physical exercises.
Cleber da Silveira Torres,Francisnaira da Silva Santos,Elen Landgraf Guiguer,Adriano Cressoni de Araujo,Sandra Maria Barbalho,Patricia Cincotto dos Santos Bueno,Maricelma Silva Soares de Souza,Danilo 한국식품영양과학회 2019 Journal of medicinal food Vol.22 No.1
Morinda citrifolia (MC) and Annona muricata (AM) are popularly used for the treatment of several diseases, including cancer. Our objective was to evaluate the effects of the juice of the MC fruit, and the ethanolic extract of AM leaves on Erhlich tumor cells, in mice and in vitro fibroblastic cells. The animals were divided into G1 and G2: controls; G3: treated with AM, and G4 juice: treated with MC. The animals were subjected to intraperitoneal inoculation of 103 tumor cells and then treated with the plants. G1 and G2 received a saline solution. Cells were grown in RPMI 1640 medium, supplemented with 10% fetal bovine serum, and maintained at 37°C in 5% CO2 atmosphere. After growth, the cells were trypsinized and incubated again. Subsequently, serial dilution of extracts and juice was performed and incubated again for 48 h. We evaluated the ascites growth, the survival rate, and cytotoxicity in fibroblast cells. AM and MC did not interfere in the ascites pattern. MC, but not AM showed significance in the survival rate. Both AM and MC produced cytotoxicity activity in T3T cells. Despite advances in medicine, cancer is still one of the leading causes of death in the world and traditional medications are not always effective. The use of MC may bring beneficial effects to patients since they interfere with different mechanisms of action during carcinogenesis. However, we suggest that further investigations should be performed.
Adriana Maria Ragassi Fiorini,Sandra Maria Barbalho,Elen Landgraf Guiguer,Marie Oshiiwa,Claudemir Gregorio Mendes,Rogerio Lopes Vieites,Agnaldo Bruno Chies,Priscilla Bianca de Oliveira,Maricelma da Si 한국식품영양과학회 2017 Journal of medicinal food Vol.20 No.11
Worldwide prevalence of noncommunicable chronic degenerative diseases is among the main causes of death worldwide. The consumption of some foods such as nuts and seeds may be beneficial in preventing these diseases. Dipteryx alata Vogel (DA), known popularly as Baru, belongs to the family Fabaceae and is a native fruit tree from the Brazilian savanna. The purpose of this study was to evaluate the use of seeds of DA on the metabolic and oxidative profile of Wistar rats. Animals were divided randomly into four groups (n = 10): G1 (control group), and G2 (treated with DA 20%), G3 (treated with DA 30%), and G4 (treated with DA 40%). After 40 days, animals were euthanized and metabolic and oxidative profiles were analyzed (glycemia, cholesterol, triglycerides [TGs], high-density lipoprotein-cholesterol [HDL-c], very low-density lipoprotein-cholesterol [VLDL-c], low-density lipoprotein-cholesterol [LDL-c], C reactive protein, aspartate aminotransferase, alanine aminotransferase, Lee index, weight, visceral fat, ferric reducing ability of plasma, and ferric–xylenol orange method. The use of the seeds was effective in reducing TGs, VLDL-c, LDL-c, and increasing HDL-c but did not interfere in the percentage of weight gain, visceral fat, levels of total cholesterol, and oxidative stress. Based on our results, it is possible to say that the use of DA may improve the lipid profile of Wistar rats and we may suggest that the consumption of DA almonds or products prepared with them may be an effective option for the intake of healthy products.
The Role of Resveratrol in Mild Cognitive Impairment and Alzheimer's Disease: A Systematic Review
Daiene Santos Buglio,Ledyane Taynara Marton,Lucas Fornari Laurindo,Elen Landgraf Guiguer,Adriano Cressoni Arau´jo,Roge´rio Leone Buchaim,Ricardo de Alvares Goulart,Cla´udio Jose´ Rubira,Sandra M. Barb 한국식품영양과학회 2022 Journal of medicinal food Vol.25 No.8
Advancing age is one of the risk factors for developing many diseases, including cancer, cardiovascular disorders, and neurodegenerative alterations, such as mild cognitive impairment (MCI), and Alzheimer's Disease (AD). Studies have indicated that supplementation with resveratrol (RSV) might improve cerebrovascular function and reduce the risk of developing dementia. Thus, the aim of this systematic review was to assess the effects of RSV on MCI and AD. MEDLINE-PubMed, Cochrane, and EMBASE were used to perform the search, and PRISMA guidelines were followed. Five studies met the eligible criteria; three with AD and two with MCI. In AD patients, the use of RSV reduces Aβ levels, improves brain volume, reduces the Mini-mental status score, and improves AD scores. In patients with MCI, this polyphenol prevents decline in Standard Volumes of Interest and increases the Resting-state Functional Connectivity score. RSV can activate the human silent information regulator 2/sirtuin 1 (Sirt-1) and can inhibit the cyclooxygenase-2 (COX-2), 5-lipoxygenase, and nuclear factor-κB, resulting in the reduction of the proinflammation pathways. It is also associated with the increase in the levels of interleukin (IL)-10 and reduction of interferon-γ and IL-17. Both anti-inflammatory and antioxidant effects can be related to preventing neurodegenerative diseases, doing maintenance, and enabling the recovery of these conditions directly related to inflammation and oxidative stress. We suggest that the use of RSV can bring beneficial effects to patients with MCI or AD.