Early CT Findings of Coronavirus Disease 2019 (COVID-19) in Asymptomatic Children: A Single-Center Experience

Lan Lan,Xu Dan,Xia Chen,Wang Shaokang,Yu Minhua,Xu Haibo 대한영상의학회 2020 Korean Journal of Radiology Vol.21 No.7

Objective: The current study reported a case series to illustrate the early computed tomography (CT) findings of coronavirus disease 2019 (COVID-19) in pediatric patients. Materials and Methods: All pediatric patients who were diagnosed with COVID-19 and who underwent CT scan in Zhongnan Hospital of Wuhan University from January 20, 2020 to February 28, 2020 were included in the current study. Data on clinical and CT features were collected and analyzed. Results: Four children were included in the current study. All of them were asymptomatic throughout the disease course (ranging from 7 days to 15 days), and none of them showed abnormalities in blood cell counts. Familial cluster was the main transmission pattern. Thin-section CT revealed abnormalities in three patients, and one patient did not present with any abnormal CT findings. Unilateral lung involvement was observed in two patients, and one patient showed bilateral lung involvement. In total, five small lesions were identified, including ground-glass opacity (n = 4) and consolidation (n = 1). All lesions had ill-defined margins with peripheral distribution and predilection of lower lobe. Conclusion: Small patches of ground-glass opacity with subpleural distribution and unilateral lung involvement were common findings on CT scans of pediatric patients in the early stage of the disease.

A New Traffic Congestion Detection and Quantification Method Based on Comprehensive Fuzzy Assessment in VANET

( Lanlan Rui ),( Yao Zhang ),( Haoqiu Huang ),( Xuesong Qiu ) 한국인터넷정보학회 2018 KSII Transactions on Internet and Information Syst Vol.12 No.1

Recently, road traffic congestion is becoming a serious urban phenomenon, leading to massive adverse impacts on the ecology and economy. Therefore, solving this problem has drawn public attention throughout the world. One new promising solution is to take full advantage of vehicular ad hoc networks (VANETs). In this study, we propose a new traffic congestion detection and quantification method based on vehicle clustering and fuzzy assessment in VANET environment. To enhance real-time performance, this method collects traffic information by vehicle clustering. The average speed, road density, and average stop delay are selected as the characteristic parameters for traffic state identification. We use a comprehensive fuzzy assessment based on the three indicators to determine the road congestion condition. Simulation results show that the proposed method can precisely reflect the road condition and is more accurate and stable compared to existing algorithms.

감정조절 유능성과 경력만족의 관계에서 다차원 셀프리더십의 매개효과

Lanlan Kong,김윤정,마지광 한국자료분석학회 2017 Journal of the Korean Data Analysis Society Vol.19 No.5

A few studies have suggested several factors that affect people's positive attitude toward career, namely, career satisfaction. These studies have focused mainly on individual characteristics, such as personality, disposition. but have not taken into account personal competence, which can also explain individual differences. Accordingly, this study aims to apply the factor of emotional regulation competence, explore the effect of emotional regulation competence on career satisfaction, and the mediation of multiple self-leadership between these two factors. A quantitative survey methodology was utilized to collect data on 299 employees who have worked in the tourism service industry at Jeju. SPSS macro was used to analyze multiple mediating effects. The results are as follows. First, emotional regulation competence was positively associated with career satisfaction and multiple self-leaderships (behavior-focused strategy, natural reward strategy, constructive thought strategy). Second, in the relationships between multiple self-leaderships and career satisfaction, only natural reward strategy had significant influence on career satisfaction. Third, natural reward strategy had partially mediated the relationship between emotional regulation competence and career satisfaction. These findings show the significant role of emotional regulation competence on career satisfaction, and the importance of intrinsic reward in improving career satisfaction. 일생동안 축적된 경력에 대한 호의적인 태도인 경력만족은 다양한 요인들에 설명되고 있다. 기존연구에서 경력만족은 성격 및 성향과 같은 개인 특성에서 그 원인을 규명하고 있으나, 개인 차이를 반영하는 유능성으로 범위를 확대할 수 있다. 이에 본 연구에서는 감정유능성의 요소인 감정조절 유능성의 다차원 셀프리더십에 대한 영향력, 감정조절 유능성과 다차원 셀프리더십의 경력만족에 대한 역할, 그리고 감정조절 유능성과 경력만족의 관계에서 다차원 셀프리더십의 매개효과를 입증하고자 하였다. 자료수집은 제주지역에 소재하는 관광 서비스 업종 종사자를 대상으로 하였으며, 299명으로부터 획득된 자료를 분석에 활용하였다. 분석과정은 SPSS macro를 활용하여 다중 매개효과를 수행하였다. 실증분석 결과, 감정조절 유능성은 경력만족과 다차원 셀프리더십(행동지향전략, 자연보상전략, 건설적사고전략)에 긍정적인 영향력이 확인되었고, 다차원 셀프리더십 가운데 자연보상전략만이 경력만족의 원인으로 규명되었다. 감정조절 유능성과 경력만족의 관계에서 다차원 셀프리더십의 매개효과는 자연보상전략을 통한 경로만이 부분 매개효과가 있는 것으로 입증되었다. 이러한 결과는 경력만족에 있어 개인 차이를 반영하는 감정조절 유능성의 중요성을 입증하는 것이며, 경력만족을 위한 자기관리활동에 있어 내재적 보상의 중요성을 보여주고 있다.

Integrated Design and Evaluation System for the Effect of Rest Breaks in Sustained Mental Work Based on Neuro-physiological Signals

Lanlan Chen,Junzhong Zou,Takenao Sugi,Masatoshi Nakamura,Shuichiro Shirakawa 제어·로봇·시스템학회 2010 International Journal of Control, Automation, and Vol.8 No.4

Rest breaks are very important to prevent the accumulation of mental fatigue in sustained mental work environments. In this research, an integrated design and evaluation system for fatigue and relaxation is proposed, which consists of subjective scale, performance assessment and neurological signals. A work-rest schedule containing mental calculation and rest break is designed to reflect effect of prolonged cognitive work and rest time in mental work environments. Inter-individual difference has been taken into account to extract common features. The results indicate that rest breaks in sus-tained mental work are effective to counteract mental fatigue and improve work efficiency. Rest breaks are widely recommended in practical mental work circumstance. Integrated analysis from multi-estimators is helpful to improve the validity and explore the underlying mechanisms central to mental fatigue. Electroencephalogram (EEG) signals at occipital region show high correlation with performance. Thus EEG signals can contribute to the efficient design of work-rest schedule.

TGF-β1 induces VEGF expression in human granulosa-lutein cells: a potential mechanism for the pathogenesis of ovarian hyperstimulation syndrome

Lanlan Fang,Yiran Li,Sijia Wang,Yuxi Li,Hsun-Ming Chang,Yuyin Yi,Yang-yang Sun,Avinash Thakur,Peter C. K. Leung,Jung-Chien Cheng,Ying-Pu Sun 생화학분자생물학회 2020 Experimental and molecular medicine Vol.52 No.-

Ovarian hyperstimulation syndrome (OHSS) is one of the most serious and iatrogenic complications that can occur during in vitro fertilization treatment. Although the pathogenesis of OHSS is not fully understood, vascular endothelial growth factor (VEGF) has been recognized as an important mediator of the development of OHSS. Transforming growth factor-beta-1 (TGF-β1) is known to regulate various ovarian functions. However, whether VEGF can be regulated by TGF-β1 in human granulosa cells has not been determined. In addition, the role of TGF-β1 in the pathogenesis of OHSS remains unknown. In the present study, we demonstrate that TGF-β1 stimulates VEGF expression in and secretion from both immortalized human granulosa-lutein (hGL) cells and primary hGL cells. Our results demonstrate that the SMAD2/3, ERK1/2, and p38 MAPK signaling pathways are involved in TGF-β1-induced VEGF expression and secretion. Using a mouse OHSS model, we show that the expression levels of TGF-β1 and VEGF are increased in the ovaries of OHSS mice. Blocking TGF-β1 signaling inhibits the development of OHSS by attenuating VEGF expression. Moreover, clinical results reveal that the protein levels of TGF-β1 and VEGF are increased in the follicular fluid of patients with OHSS, and that the levels of these two proteins in the follicular fluid are positively correlated. The results of this study help to elucidate the mechanisms by which VEGF expression is regulated in hGL cells, which could lead to the development of alternative therapeutic approaches for treating OHSS.

The role of cultural intelligence in intercultural service encounters

Lanlan Kong,Sungho Ji,Zhiqiang Ma,Hyounggil Kim 한국무역학회 2017 한국무역학회 국제학술대회 Vol.2017 No.11

브랜드경험과 즐거움, 구전의도의 관계

공란란(Lanlan Kong),김형길(Hyounggil Kim),다니엘 김(Daniel J. Kim) 한국인터넷전자상거래학회 2015 인터넷전자상거래연구 Vol.15 No.3

The present study is aimed to demonstrate the causal relationships of muli-dimensional brand experience(sensory, affective, behavioral, intellectual) to pleasure and WOM intention, to investigate mediating effects of pleasure in the links between multi-dimensional brand experiences and WOM intention, and to explain the differences between South Korean and Chinese. The results are indicated as follows. First, brand experiences(sensory, affective, behavioral, intellectual) had positive effects on consumer’s pleasure in both sample. Second, it was demonstrated that brand experiences was significant causes on inducing consumers’ WOM intention for South Korean and Chinese consumers. Finally, it was demonstrated that pleasure had fully mediated in the relationship between brand experiences and WOM intention in all sample. The findings will help global marketers establish more efficient brand strategies according to the differences and similarities between South Korean and Chinese smartphone consumers.

유치원과 실버하우스 복합시설의 공간특성에 관한연구 -미국, 유럽, 일본, 중국 중심으로-

유란란 ( Liu Lanlan ),김주연 ( Kim Jooyun ),왕세학 ( Wang Shixue ) 한국공간디자인학회 2021 한국공간디자인학회논문집 Vol.16 No.4

(연구배경 및 목적) 행정안전부가 2019년에 발표한 통계에 따르면 65세 이상의 인구가 800만 명 도달했지만 한국의 전체인구는 감소하고 있다고 한다. 산업이 발전함에 따라 출산율 저하와 노령화가 급속하게 진행되면서 실버하우스의 역할이 사회에서 중요시 되고 있는 상황이다. 현재, 노인시설의 수요 증가로 어린이시설과 노인시설을 복합화하여 부지확보가 어려운 도심지를 대상으로 복합화 개념을 도입하고 있는 추세이다. 본 연구는 미국, 유럽, 일본, 중국의 유치원과 실버하우스 복합시설의 사례분석을 통해 공간구성요소의 공간특성을 파악하여 향후 유치원과 실버하우스 복합시설의 공간구성에 기초자료로 사용하는데 목적이 있다. (연구방법) 연구 방법으로는 첫째, 이론적 고찰을 통해 복합공간의 개념과 종류를 살펴보고 둘째, 노인과 어린이의 신체적, 심리적, 사회적 특징을 파악하여 공간구성요소를 도출한다. 셋째, 공간구성요소를 분류하여 공간적 특성을 도출한다. 넷째, 이를 바탕으로 해외 유치원, 실버하우스의 복합시설 5곳을 대상으로 공간특성을 도출한다. (결과) 복합공간의 공간특성은 접근성, 안정성, 활동성, 개방성, 편의성이 있으며, 사례조사를 통해 기능중심의 공간특성인 접근성, 안전성, 편의성이 전반적으로 보통 이상 평가되지만 체험활동, 교류활동과 같은 어린이와 노인이 함께 할 수 있는 활동성, 개방성과 같은 공간의 역할이 부족하다. 보호자와 관리자들의 만족도를 높여주는 기능중심의 시설기반은 마련되어 있으나, 어린이와 노인을 고려한 감각적, 체험적 공간의 요소는 다소 부족하다. (결론) 고령화에 따른 실버하우스의 급증은 표면적 성과를 나타내고자 하는 성과이다. 저출산에 따른 어린이시설 수요 감소와 고령화에 따른 실버하우스의 수요 증가로 부지확보의 어려움에 있으나, 유치원과 실버하우스 복합공간을 통해 경제적 측면의 효과와 기존건물의 개보수를 통한 재생적 측면에 탁월하다. 다만, 어린이와 노인의 신체적, 심리적, 사회적 특징을 반영한 공간특성의 요소로는 기능 중심이 아닌 사용자 중심의 공간특성의 필요성이 부상한다. 이를 적용해 어린이와 노인들의 사용에 만족도를 높이고 향후, 공간프로그램 연구를 통해 보다 효과적인 유치원과 실버하우스 복합공간이 나오리라 기대한다. (Background and Purpose) Statistics released by the Ministry of Administration and Security in 2019 show that the population over 65 years old reached 8 million, but the total population of South Korea is declining. With the development of the industry and the decline in the birth rate ,the rapid development of aging, the role of the silver house has gained more and more attention in the society. Nowadays, with the increasing demand for facilities for the elderly and children's facilities Facilities for the seniors are integrated, and the concept of integration is being introduced to the central urban area where it is difficult to secure land. This research aims at understanding the spatial characteristics of spatial components through case studies of kindergartens and silver house complex facilities in The United States, Europe, Japan, and China, as the basic data for the spatial composition of future kindergartens and silver house complex facilities. (Method) Research methods include: first, to explore the concept and types of compound space through theoretical investigation, second, to grasp the physical, psychological and social characteristics of the senior and children to derive the spatial components. Third, classify the spatial components and obtain the spatial characteristics. Fourth, on this basis, the spatial characteristics of the five comprehensive facilities of overseas kindergartens and silver houses are derived. (Results) The spatial characteristics of the comprehensive space include barrier-freeness, stability, mobility, openness, and convenience. Through case investigations, the function-centered spatial characteristics of barrier-freeness, safety, and convenience are generally evaluated above average. But experience activities; lack of the role of space, such as communication activities, activities and openness where children and the seniors can be together. The establishment of a function-centric facility infrastructure can increase the satisfaction of guardians and managers, but considering the sensory and experience space elements of children and the seniors are lacking. (Conclusions) With the aging, the surge of silver houses is the result of hope to show superficial results. Due to the decrease in the demand for low-birth children's facilities and the increasing demand for silver houses by aging, there are difficulties in land security. However, through the kindergarten and silver house integrated space, the economic benefits and the regeneration of existing buildings are important Remarkable. However, the spatial feature elements that reflect the physical, psychological and social characteristics of children and the seniors are not function-centered, but the need for user-centered spatial characteristics rises. Looking forward to applying these to improve the satisfaction of children and the seniors , in the future, through space project research, more effective kindergarten and silver house integrated spaces will appear.

중국인 학습자를 위한 ‘-고도’의 문법 설명 부분의 교재 개선 방안

송남남(Song, Lanlan) 돈암어문학회 2014 돈암어문학 Vol.27 No.-

한국어에서는 하나의 어미 뒤에 다양한 보조사를 붙이기도 한다. 그 중에 일상 언어생활에 많이 사용되고 한국어 능력시험에도 자주 출제되고 있는 ‘-고도’가 있다. 하지만 지금 중국 현지에서 활용되는 교재를 보면 ‘-고도’에 대한 기술이 매우 애매모호하다. 심지어 이에 대해 전혀 기술이 없는 교재도 있다. 이런 문제점을 염두에 두고 본고는 절과 절을 접속하는 연결어미 ‘-고도’를 연구 대상으로 삼아 ‘-고도’의 의미를 규명하고 중국인 학습자를 대상으로 하는 교재의 문법 설명의 개선 방안을 모색하는 데에 그 목적이 있다. In Korean language, various postpositional particles are attached to an ending of a word. Among them is ‘Kodo’, which is used in daily living and appears in Test of Proficiency in Korean. But ‘Kodo’ has been ambiguously explained in the textbooks which are currently used in China. Even worse, some textbooks has no explanation of that point. Considering this problem, this work focuses on the ending ‘Kodo’ which connects two clauses, and tries to understand the meaning of the ending so that proper measures for improving the contents of the textbooks for Chinese students could be found.

Semantics and Modeling of Indoor Moving Objects

Peiquan Jin,Lanlan Zhang,Jie Zhao,Lei Zhao,Lihua Yue 보안공학연구지원센터 2012 International Journal of Multimedia and Ubiquitous Vol.7 No.2