Analysis of KAP1 expression patterns and human endogenous retrovirus Env proteins in ovarian cancer

Kyung‑Yoon Jeon,Eun‑Ji Ko,Young Lim Oh,Hongbae Kim,Wan Kyu Eo,김아리,Han Gyu Sun,Meesun Ock,Ki Hyung Kim,Hee‑Jae Cha 한국유전학회 2020 Genes & Genomics Vol.42 No.10

Background Human endogenous retroviruses (HERVs) constitute around 8% of the human genome and have important roles in human health and disease, including cancers. Previous studies showed that HERV envelope (Env) proteins are highly expressed in cancer tissues and co-related with cancer progression. KAP1 has been reported to play a key role in regulating retrotransposons, including HERV-K, through epigenetic silencing. Objective The relationship between KAP-1 and HERV Envs expressions was analyzed only in tumor cell lines and has not yet been studied in cancer tissues. In this study, we analyzed the expression patterns and relationship between KAP1 and HERV Env proteins in ovarian cancer tissues. Method The expression patterns of KAP-1 and HERV Env proteins, including HERV-K and HERV-R, were analyzed in ovarian cancer tissue microarrays that contained 80 surgical specimens, including normal ovary and malignant ovarian cancers. Results The expression of HERV-R Env and KAP1 proteins is signifcantly higher in ovarian cancer compared with normal ovary tissues. However, the expression of HERV-K Env did not change signifcantly in cancer tissues. The expression patterns of HERV-K Env and HERV-R Env signifcantly increased in early stages of cancer and KAP1 expression was higher in certain stage and types of cancers. However, the expression of HERV-K Env, HERV-R Env, and KAP1 did not change in diferent age groups. The correlation between the expression of KAP1 and HERV-Env, including HERV-K and HERV-R, was not signifcantly correlated. Conclusions The results of this study showed that there was no signifcant correlation between the expression of KAP1 and HERV Env proteins in ovarian cancer tissues, unlike studies with cell lines in vitro. These results suggest that the actual expression of HERV Env proteins in ovarian cancer tissues may be regulated through various complex factors as well as KAP1.

MBTI 성격분석을 통한 체육전공학생과 일반전공학생의 차이점 연구비교

전매희,오경록 한국학교체육학회 2002 한국학교 체육학회지 Vol.12 No.1

본 연구는 체육전공학생과 일반전공학생의 성격 유형적인 차이점과 묵성을 비교하여 어떤 관계가 형성되는 지를 밝히는데 그 목적이 있다. 연구대상은 2001년 현재 경기도에 소재하고 있는 K대학교에 재학중인 대학생을 모집단으로 설정한 후, 집락무선표집법(cluster ramdom sampling)으로 표본을 추출하여 (MBTI)성격유형 검사도구를 사용하여 분석하였으며, 남자 299명(69%), 여자 100명(31%), 총 300명이었다. 이러한 실험과 실험에 따른 분석절차를 통해서 규명된 결론은 아래와 같다. 첫째 체육전공학생과 일반전공학생과의 성격유형의 차이를 경종한 결과 체육전공학생과 일반전공학생과는 성격유형의 차이가 있었다. 구체적으로 체육전공은 ESTJ(외향적 감각형)형이 높고, 일반 전공학생들은 ISTJ(내향성 감각형)형이 높게 나타났다. 둘째 체육전공학생과 일반전공학생과의 선호지표의 차이를 검증한 결과 E-I(외향형, 내향형) 성향은 차이가 있었다. 구체적으로 체육전공학생은 E(외향형)성향이 높고, 일반전공학생들은 I(내향형)성향이 높게 나타났다. 셋째 체육전공학생과 일반전공학생과의 선호지표의 차이를 검증한 결과 S-N(감각형, 직관형) 성향은 차이가 있었다. 구체적으로 체육전공학생은 S(감각형)성향이 높고, 일반전공학생은 N(직관형)성향이 높게 나타났다. 넷째, 체육전공학생과 일반전공학생과의 선호지표의 차이를 점증한 결과 T-F(사고형, 감정형) 성향은 차이가 있었다. 구체적으로 체육전공학생은 T(사고형)성향이 높고, 일만 전공학생은 F(감정형)성향이 높은 것으로 나타났다. The aim of this study is to specify the dissimilarity in character between athletes and non-athletes, and look at the nature of their relationships of personality traits. The population of this study are students from university "K", in the year 2002, located in Kyung-Gi province. After establishing I selected 300 students(31%) from using cluster random sampling method. The final step of the study involves actual analysis using MBTI psychological type indicator. As a result of such a analysis, f come to the following conclusion ; · When I study on the difference of the personality traits between the athletes and non-athletes, I find that there is a personality traits difference between two groups, Concretely, the indicator shows that the athletes can be defined as ESTJ pattern (Extraverted Sensing). · In my study of the preferences between two groups, the difference of the E-I(Extraversion, Intraversion) pattern shows. In a concrete way, the athletes are more consistent with the Extraversion trait, while the general group frequently keep the 1(Introversion) trait. · MBTI results on the difference of the preferences indicate that the difference of(T-F) traits exists. · The athletes are common to the T(thinking) traits, to the contrary, the general students are common to the F(Feeling) Traits. · There is no difference of J-P(Judging, Perceiving) traits between them. · After examining the difference of the preference, I learn to know that the athletes and the general students share the same traits(S-N, I-F, J-P).

Aerobic Training이 女學生들의 肺機能 및 PWC170에 미치는 影響

全廷祐,金耕知 慶熙大學校 體育科學大學 1990 體育科學論叢 Vol.- No.3

The purpose of this study was to determine one effect of ten week of aerobic training on pulmonary function and physical work capacity The subject all female were collected from the K university The results of the study were as follow ; in the FVC the subjects improved from 3.29 ±0.22ml to 3.46 ±0.18ml after training with 5.2% increase. The subjects also improved from 2.48 ±0.21 to 2.67 ±0.2 in the FEV 1.0, from 5.86 ±0.42 to 6.28 ±0.58 in the PF. However all the values were statistically not significant in the PWC170 by kpm/min the subjects improved from 673.2 ±54 to 691.6 ±49, with 2.73% increase. In the PWC170 by kpm/kg/min the subject improved from 11.75 ±1.11 to 12.34 ±1.26, with 5.02% increase. The subjects also improved from 16.40 ±1.29 to 16.60 ±1.25 in PWC170 expressed by kpm/kg(L.B.M)/min all the values were however statistically no significant.

아프리칸 방염기법을 이용한 섬유디자인 연구

전경애 東義大學校 生活科學硏究所 2001 生活科學論集 Vol.5 No.-

The study consists of combining traditional Resist-Dyeing techniques, which are utilized extensively by the Yoruba people of West Africa, and fabric design created by using these techniques. This approach not only enhances the aesthetic expression of fine textiles but also developes fabric design through another medium and methodology. The goal is explore and exploit combining new materials and designs with ancient tradition, therefore, such an ancient tradition as Yoruba adire cloth could also progress and develop.

중등교사신규임용후보자선정경쟁시험의 프랑스어 과목 평가영역 설정 및 평가내용요소 상세화에 관한 연구

전경준 韓國敎員大學校 敎育硏究院 2008 敎員敎育 Vol.24 No.2

The purpose of this study is to propose the evaluation area standards and content standards for French Teacher Employment Examination, according to the improvement policy of the teacher selection system which is reorganized with first selective style, secondary statement style and 3 in-depth interview and teaching ability. In this paper, we propose 6 evaluation areas for French language teaching (understanding the French curriculum, French teaching methodology, French class practice, French teaching materials analysis, evaluation, communication skills), 5 for French language competence (Pronouciation and spelling, vocabulary, grammar, French conversation, French composition), 4 for French linguistics (general linguistics, phonetics and phonology, morphology and syntax, semantics and pragmatics), 3 for French literature (literary theory, history of French literature, French writers and analysis works) and 4 for culture of French-speaking countries/Francophonie (educated culture, life culture, actualites, mutual culture). 본 연구는 교원 양성 체제 개편에 따른 교원 선발제도의 개선 정책이 확정ㆍ발표됨으로써,이에 따른 “교육공무원임용후보자선정시험”이 과거의 2차 시험에서 1차 선택형,2차 논술형,3차 심층면접 및 수업능력 평가 등 3단계 체제로 개편되어 이와 같은 전형의 취지에 부합하는 출제·채점 체제 개발과 출제 근거를 명료화하고 객관화시키기 위한 임용시험 프랑스어 과목 평가영역의 설정 및 평가내용요소 상세화 등을 연구하는 것을 목표로 한다. 이를 위해 프랑스어 평가영역을 프랑스어교육학 6개 평가영역,프랑스어능력 5개 평가영역,프랑스어학개론 4개 평가영역,프랑스문학개론 3개 평가영역,프랑스어권문화 4개 평가영역을 교원자격검정령,교원자격검정령 시행규칙 등 관계법령,교사자격무시험검정 기준법령 상의 프랑스어 과목 기본이수과목(또는 분야),전공과목별 교사 자격 기준,전국 사범대학 프랑스어교육과의 교육과정,개정7차 고등학교 프랑스어 교육과정에 의거하여 제안하고,각각의 평가영역에 대해 각 영역의 소단원이나 핵심 주제를 중심으로 평가내용요소 상세화를 제시한다.

황색종 및 기타 피부질환에 있어서의 혈청지질 및 지질단백질 농도에 관한 연구

전경준,김용환,장진요 중앙대학교 의과대학 의과학연구소 1981 中央醫大誌 Vol.6 No.2

Serum lipid and lipoproetin levels were measured in order to compare with xanthoma and other dermatologic diseases. The measurement was done in 11 patients with xanthoma and 131 patients with other dermatologic diseases. The results are summarized as follows: 1. The levels of the serum lipid and lipoprotein of the patients with other dermatologic diseases were not different from that of the normal populations. 2. Eleven patients with xanthoma corresponded to Types IIb (5 cases), Ⅲ(4 cases) and Ⅳ (2 cases) of WHO classification. 3. The serum lipid and lipoprotein levels were higher significantly in the patients with xanthoma than in the patients with other dermatologic diseases.

프랑스어과 교사 일반연수 프로그램(교육과정)에 관한 연구

전경준 한국 프랑스어문교육학회 1999 프랑스어문교육 Vol.8 No.-

Cet article a pour but de proposer un programme modele pour le stage de formation continue des professeurs de francais langue etrangere au lycee. Apres avoir insiste la necessite du stage, on analyse des facteurs qui doivent etre pris en consideraction pour elaborer le programme : l'objectif de l'enseignement du francais langue etrangere au lycee, les demandes et besoins langiers des professeurs et les conditions formelles imposees par le ministere (telles que les heures minima du stage). En tenant compte de ces facteurs, on propose un programme de 60 heures. Les cours se divisent en trois grandes categories : cours d'enseignement general, didactique du FLE et cours de francais. Pour les cours d'enseignement genera1, on propose 'la conference du directeur de l'etablissement', 'la civilisation francaise' et 'les mentalites et comportements des Francais'. Les cours de didactique du FLE comprennent 'la production/l'elaboration des ressources pour les cours du FLE', 'le mutimedia et l'enseignement du FLE' et 'l'evaluation et les specifcites de l'enseignement du FLE'. Pour les cours de francais, on propose 'la conversation en situation', 'la conversation socio-culturelle', 'la comprehension orale par l'internet' et 'les activites pedagogiques en francais'.

부부간 의사소통 유형이 결혼만족도에 미치는 영향

전귀연,구순주,박경란 인제대학교 아동ㆍ가족복지연구소 1998 아동ㆍ가족복지연구 Vol.2 No.-

The purpose of this study was to identify the influence of marital communication style on marital satisfaction. For this purpose, two instruments were administrated to 352 couples who were mothers and fathers of the students attending five middle shcholols in Taegu. The instruments of measurement were Martal Satisfaction Scale and Marital Communication Scale. Factor Analysis. Cronbach' a and multiple regression were conducted for the data analysis. Major findings of this study were as follows: 1) In the case of wives, the style of marital communication influencing on marital satisfaction were rational attitude and reproachful attitude of hushand. 2) In the case of husbands, the style of marital communication influencing on marital satisfaction were rational attitude, concessive attitude, and unconcerned attitude of wife.

미국산 청바지에 대한 소비자 태도의 비교문화 분석 : 한국과 멕시코의 남녀소비자를 대상으로 among Korean and Mexican consumers

전경숙,Kim, Jai-Ok 한국의류학회 1996 한국의류학회지 Vol.20 No.3

An understanding of consumers' evaluative processes and the consumer variables that influence cross-cultural evaluations of foreign products is essential to effectively penetrate international markets. This study compared consumers in two developing countries, Korea and Mexico, regarding their product evaluations and purchase intentions for US Levi's jeans. Both Korean and Mexican consumers are generally quality and price conscious. Korean consumers appeared to be more value-conscious than Mexican consumers. Mexican consumers exhibited high level of brand and prestige conscious behavior. Findings in this study support that culture bound consumer characteristics vary from country to country resulting in differences in perception of quality, value and purchase intentions for a particular product. The perception of product quality differs from perception of value and subsequent willingness to buy. For a comprehensive understanding of consumer purchase behavior, the impact of value-conscious attitude on percetion of quality and on purchase intentions should be examined.

건축물의 LCC Database 구축에 관한 연구

전찬민,우경헌,김중현,김경업,박태근 목원대학교 건축도시연구센터 2003 建築·都市環境硏究 Vol.11 No.-

The importance of LCC analysis has been enlarged. Also, it would be necessary to computerize LCC analysis for accurate and logical analysis of LCC. In other papers, they showed LCC analysis model but the study of database development which could be applied in LCC analysis have been undeveloped. This study showing the development of common database for the LCC analysis computerization inquires into cost breakdown structure by previous researches. Also, it makes cost breakdown structure for deriving LCC cost item. As a result, the standard of LCC analysis computerization by developing LCC DB of cost breakdown structure would be shown.