β-1,3/6-linked glucan 첨가사료가 넙치의 비특이적 면역반응에 미치는 영향

원경미,김수미,박수일 한국어병학회 2004 한국어병학회지 Vol.17 No.1

glucan 첨가 사료 투여가 넙치에 미치는 영향을 조사하기 위하여 넙치에 glucan 0%, 0.01%, 0.1%, 0.5% 첨가 사료를 연속 투여구와 격주 투여구로 나누어 공급하면서, 성장, 혈액 성분, 비특이적 면역능을 분석하였으며, 나아가 어병 세균인 Edwardsiella tarda균의 공격 실험에 대한 방어능을 조사하였다. gulcan 첨가 사료 투여는 넙치의 성장에 긍정적인 효과를 보였는데, 특히 0.05% 연속 투여구와 0.1% 격주 투여구에서 대조구보다 유의하게 높은 성장을 나타내었다. glucan 첨가사료의 투여가 넙치의 비특이적 면역 반응에 미치는 영향을 조사하기 위해 혈청 lysozyme과 전신 식세포의 확성 산소를 측정한 결과, 거의 모든 실험구에서 실험 기간 내내 대조구보다 높은 활성을 보였다. glucan 첨가 사료의 투여가 넙치의 생리에 영향을 미치는 지를 조사하기 위하여, total protein, glucose, GOT, GPT, Ht를 측정한 결과, 3주째 GPT 수치가 다소 높은 것을 제외하고는 그다지 큰 변화를 보이지 않았다. 마지막으로 Edwardsiella tarda (4×10^(6) cells/fish) 균을 공격 실험한 결과, 0.01% 연속 투여구를 제외한 모든 실험구에서 높은 방어력을 보였다. The effects of dietary β-1,3/1,6-linked glucan administration on nonspecific immune responses, hematology and disease resistance against Edwardsiella tarda in olive flounder, Paralichthys olivaceus were evaluated. Fish were fed the experimental diets supplemented with 0 %, 0.01 %, 0.05 %, 0.1 %, and 0.5 % of β-glucan to a commercial diet for 7 weeks. The test was performed in two ways such as fed on each β-glucan concentrations daily and every other week alternately. The body weight gain from the fish fed on daily the 0.05 % supplemented diet and fed on alternately the 0.1 % supplemented diet of β-glucan were significantly higher than the control. Both lysozyme activity and intracellular superoxide anion production of kidney phagocytes were higher in the all experimental groups than in the control. But there was no large difference in hematology among each group. The relative percent survival rate (RPS) after an artificial challenge with 4×10^(6) cells of E. tarda per fish was higher than the control, except for that fed on daily the 0.01 % supplemented diet.

악골의 낭종 적출술 후 발생한 골결손부의 자발적인 골 재생

김경원, 이은영 충북대학교 의과대학 충북대학교 의학연구소 2012 忠北醫大學術誌 Vol.22 No.1

비교적 크기가 큰 하악골의 낭종성 병소에 대하여 낭종적출술 후에 발생하는 골결손부에 대하여 즉 각적인 골이식술을 시행하지 않아도, 골결손부가 자연적으로 골재생이 일어난다는 보고들이 최근에 발 표되고 있다. 본 연구는 하악골에 발생한 비교적 크기가 큰 낭종성 병소의 낭종적출술 후 생긴 골결손 부에 대하여 특별한 골이식등의 술식 없이 일차봉합술만 시행한 후에 골결손부가 자발적으로 치유되는 과정을 관찰하고 이에 관여하는 요소들에 대한 것을 확인하고자 한다. 파노라마 방사선사진의 술전, 수술 직후, 술후 1개월, 3개월, 6개월, 1년을 관찰하여 하악골의 낭종 적출술 후 골결손부의 자연적인 골재생 정도를 평가하여 향후 유사한 증례에 대한 치료에서 통상적인 골이식술 없이 낭종적출술 및 일차봉합술을 통한 치료전략을 세우는데 도움을 주고자 한다.

음악가에서의 과 사용 증후군환자에 대한 임상양상

서경묵,서경호,김성원 大韓再活醫學會 1998 Annals of Rehabilitation Medicine Vol.22 No.6

남녀평등교육의 두 접근방식에 나타난 교육기회균등과 가치 문제 분석

조경원 이화여자대학교 한국문화연구원 1992 韓國文化硏究院 論叢 Vol.61 No.3

There are two approaches to education for women liberation. One is the gender-free approach which attempts to ignore gender or to be free from gender-bias in education. The other is the gender-sensitive approach which pays attention to gender in order to prevent gender bias and inequality. The first approach argues for co-education, having come to the realization that sex-segregated education has been both different and unequal. In contrast, the second approach calls for women-centered education since our society, education and perceptual frameworks are themselves too gender-biased. The gender-free education has been supported in the tradition of Liberal Feminism, while the gender-sensitive education has recently been claimed by the Radical Feminists and the Social Feminists. The Liberal Feminists tend to emphasize the same education for women as for men. Focusing on the alleged inferiority of women, they want to redress sexual inequality as a result the stereotyping of expected role s for men and women and the translation of these into curricula. They emphasize equal educational opportunities between the sexes by ignoring gender as an access barrier (from admission to specific educational institutions and programs to opportunities for participations). They claim for women an education in the "masculine" virtues of rationality and independent judgment, while they claim for men an education in the "feminine" virtues of nurturance and care. They argue that single-sex schools or classes have fostered different and unequal education for men and women. In this tradition, co-education has been a major trend in public schools since ignoring gender has enabled us to move to co-education. Acknowledging power relations between men and women, the Radical Feminists and the Social Feminists argue for women-centered education, which aims at empowering women to change their position and, therefore, society. Believing that our current educational system tends to perpetuate patriarchal social relation, they began to question the assumptions underlying co-education, examining the manner in which the school under-evaluates womens performance even when they do better than men at the same activity. Arguing that male control of education has shaped the nature of education and knowledge promulgated schools, they question the dominant code of knowledge, the styles of pedagogy, and the ideals of the educated person. Feminist Pedagogy in this tradition legitimates womans personal experience as an appropriate arena of intellectual inquiry when facing established knowledge about women and social reality. Taking the everyday lives of women seriously, they challenge what has been defined as significant or valuable in our society.

제 1형 신경섬유종증 환자에서 발생한 위장관 간질종양 1예

원경준,이준,변유미,조민근,한경택,김원,홍란,임성철,김경종,김영대,박찬국,김만우 朝鮮大學校 附設 醫學硏究所 2007 The Medical Journal of Chosun University Vol.32 No.2

Gastrointestinal stromal tumor (GIST) is the most common non-epithelial neoplasm arising in the gastrointestinal tract, but this tumor is rarely seen in association with type l neurofibromatosis (NFl) Generally, the majority of GISTs are isolated neoplasm and they are sporadically found in the stomach, but the GISTs in NFl patients are usually multiple and usually found in the small intestine. We report a case of multiple GISTs in the jejunum of a 63-year-old woman diagnosed as NFl accompanied by complication of gastrointestinal bleeding, In this case, Patient had multiple cafe-au lait spots and neurofibroma on skin and had freckling on axilla and groin, and then, we made a diagnosis of NFl. Gastrointestinal bleeding is controlled by resection of multiple GISTs. Generally, only 3-5% of all gastrointestinal bleeding comes from the small bowel. Causes of small intestinal bleeding are angiodysplasia, neoplasm, NSAIDs induced ulcer etc. but, If patients have NFl accompanied by complication of gastrointestinal bleeding, GISTs on small bowel must be considered.

고관절 전치환술시 응용프로그램을 이용한 수술 전 계획

원중희,김용민,최의성,손현철,박경진,남기세,정재중 대한고관절학회 2003 Hip and Pelvis Vol.15 No.3

엔진 냉각계의 방열량 해석에 관한 연구(Ⅰ)

원종필,방청세,마상용,박경석 慶熙大學校 1997 論文集 Vol.26 No.-

The higher output levels attained by automotive engines recently been accompanied by an increase in the amount of heat released by the engine. This higher heat release level has caused the thermal load in the engine compartment to rise. As a result, greater emphasis has been placed on thermal analysis of heat radiation from the radiator and of heat release from the engine. Heat release the coolant from the engine is released with heat transfer. It is. thus, the essential element to analysis of heat transfer process in cooling system for an automotive engine. However, most of the research about heat release to the coolant is performed from the standpoint combustion, so this research is done from the standpoint of heat transfer to the cooling system including the engine coolant. This study is performed on the analysis of heat release chracteristics in cooling system for an automotive engine according to the operating and cooling conditions. The results are summarized as follows: 1. The heat release is increased according as coolant temperature is decreased and coolant flowrate is increased. 2. The heat release is increased and heat release per power is decreased according as engine is increased with same engine speed. 3. The heat release is increased by increasing fuel comsumption according as engine speed increased.

동종골과 이종골을 층별로 이식한 상악동골이식술

김경원, 이은영 충북대학교 의과대학 충북대학교 의학연구소 2013 忠北醫大學術誌 Vol.23 No.2

치조골의 흡수와 상악동의 함기화로 인하여 상악 구치부에서 임플란트 식립을 위한 상악동골이식술은 이미 보편화된 술식이며, 그 예후도 아주 양호한 것으로 알려져 있다. 최근 조직은행 등을 통하여 다양 한 동종골 이식재들이 공급되고 있으며 또한 그 이식재의 특성도 비교적 양호한 것으로 알려져 있다. 그러나 동종골 이식재는 비교적 흡수가 빨리 일어나는 단점이 있어서 이에 대한 보완으로 이종골이나 합성골을 섞어서 사용하여 이식재의 빠른 흡수를 줄이려는 노력이 있어 왔다. 저자는 상악동골이식술 시 동종골과 이종골을 섞어서 이식하는 것이 아니라 상악동저의 환자의 자기 골조직과 접촉되는 부분은 동종골을 이식하고, 상부의 상악동점막에 접촉하는 부분은 이종골을 이식하 여 흡수에 보다 저항할 수 있도록 동종골과 이종골을 층상으로 골이식술을 시행하여 비교적 양호한 결 과를 얻었다.

농구 선수의 만성 슬개건염

서경호,서경묵,김성원,김백곤,송인섭 大韓再活醫學會 1998 Annals of Rehabilitation Medicine Vol.22 No.6

반복적인 부비동염으로 내원한 Good 증후군 1예

송경호,김계형,김충종,박경운,전상훈,김홍빈,김남중,오명돈,최강원 대한감염학회 2007 감염과 화학요법 Vol.39 No.5

Good 증후군은 흉선종과 면역결핍이 동반되는 질환으로, B세포의 감소로 인한 범저감마글로불린혈증과 CD4^(+)T세포의 감소로 인한 세포성 면역저하가 동시에 나타나는 것을 특징으로 한다. 본 증례는 18개월 전부터 발생한 반복적인 부비동염을 주소로 내원한 43세 남자 환자로, 내원 1년 전 흉선종절제수술을 시행받았으며, 면역학적 검사상 범저감마글로불린혈증과 T세포의 감소 등의 이상 소견이 발견되었다. 정주 면역글로불린과 경험적 항생제(amoxicillin/clavulanic acid) 사용 후 부비동염이 호전되었으며, 예방접종과 정기적인 면역글로불린 투여 후 특이 합병증없이 경과 관찰 중이다. Good's syndrome is the association of thymoma with immunodeficiency, characterized by hypogammaglobulinemia, B-cell lymphopenia and variably defects in cellular immunity with CD4^(+) T-cell lymphopenia and an inverted CD4^(+):CD8^(+) T-cell ratio. We report a 43-year-old male patient who presented with a 18-month history of productive cough and postnasal drip. One year ago, he underwent the operation for resection of a thymoma. Despite of appropriate management, sinusitis relapsed multiple times. He was found to have hypogammaglobulinemia with nearly absent B cells(4/μL). The CD4^(+) T-cell count was 554/μL with an inverted CD4^(+):CD8^(+) T-cell ratio of 0.6. His symptoms and signs improved with antibiotic treatment and monthly administration of intravenous immunoglobulin (IVIG, 400 mg/kg).