일개 대학병원에 내원한 원발성 폐암 환자의 인구학적 및 병리학적 특성

주혜원,강경필,김민근,박민석,임현민,이현경,이성순,이영민,김주인,염호기,최수전,이혁표 인제대학교 2006 仁濟醫學 Vol.27 No.-

Background : Recently, the lung cancer mortality rank first in Korea. The prognosis of lung cancer is not good enough with current treatments and multimodality treatments are required. So we are interested in the characteristics of lung cancer patients for better treatment. Methods : We searched lung cancer patients since 1994. Then we collected the data of primary lung cancer patients about the demographic features, histologic types and diagnotic methods. We divided the total period into 2 haves and specific analysis was tried. Results : 1) Total 850 patients were included. 633 (74.5%) were male and 217 (25.5%) were female. 2) The mean age was 65 ± 11 years old. and the peak age was 7th decades. 3) Squamous cell carcinoma(334/850, 39.3%) was slightly more prevalent than adenocarcinoma(302/850, 35.5%). Conclusion : From these results, we expected that older persons will be diagnosed to have lung cancer and adenocarcinoma will be more dominant histologic type with time.

배송업무 아웃소싱 모델

송경주,임석철 한국경영과학회 2000 한국경영과학회 학술대회논문집 Vol.- No.1

최근 기업들은 자사의 핵심역량을 극대화하기 위하여 배송업무를 포함한 물류업무를 전문적인 제3자에게 위탁하는 아웃소싱이 확대되는 추세이다. 특히 제조업체는 제품 배송업무의 아웃소싱을 다양한 형태로 추진할 수 있기 때문에 아웃소싱 계획단계에서 최적의 업무프로세스 모델링이 매우 중요하며, 자사에 맞는 아웃소싱 모델을 선정하도록 의사결정을 지원할 체계적인 접근방법이 필요하다. 본 연구는 배송업무 아웃소싱 현황을 조망하고, 배송업무 아웃소싱을 위한 고려사항과 업무절차를 배송전문업체 선정단계와 운영단계, 그리고 성과평가단계로 구분하여 제시한다.

대학교 가정학 교양과목의 교과내용구성과 수업운영방식 : Focused on Child and Family, Clothing and Textiles, Food and Nutrition, and Housing 아동가족·의생활·식생활·주생활 영역을 중심으로

박경옥,이소은,김은영,김운주 충북대학교 교육·생활연구소 1999 생활과학연구논총 Vol.2 No.-

The purposes of this study were to: (1) analyze students' educational needs and attitude concerning various areas in Home Economics as a college-level liberal education curriculum, (2) provide data concerning future curricula and efficient teaching method. Four areas of Home Economics were investigated: child and family, clothing and textiles, food and nutrition, and housing. The subjects of this study were 478 students of Chungbuk National University, divided by experiences in enrollment of Home Economics and teaching methods (managed by 1-2 teachers vs. team teaching by 4 teachers). The data were collected by questionnaires developed by the researchers and analyzed by frequencies, t-test and x²-test The major findings were as follows: 1) Child and family education, especially the subjects of child-rearing and parents education, was most needed area by students, and this area also got highest score in attitude. 2) In the field of clothing and textiles, the subject of impression management with clothing was needed the most, and the importance of clothing got the highest score in attitude. Also, the students enrolled Home Economics showed more educational needs and practical attitude. 3) In the field of food and nutrition, food safety and sanitation were the most needed subject and safety of foods making got the highest score in attitude. The students enrolled Home Economic showed more educational needs on the subjects of food safety and sanitation, human nutrition and health maintenance and the culture of food and nutrition. 4) Educational need of the students was the lowest in housing area, though the subjects of knowledge on the space planning such as interior design, use of living space, and indoor environments-heat, light and air got most attention. Educational needs and attitudes of the students were affected by student's sex, major (human vs. scientific), and age. 5) Educational needs and attitudes of the students were affected by sociodemographic variables, such as grade, sex, major (human vs. scientific), and age. And teaching method was also found to be an influential factor.

정신분열병 환자의 신경인지기능 결함 유형

백주희,이호택,장호균,박병관,이상연,김은경 大韓神經精神醫學會 1999 신경정신의학 Vol.38 No.2

연구목적 : 정신분열증의 인지기능장애가 전반적인 결함인지 아니면 특정한 결함인지 논란이 지속되고 있다. 본 연구에서는 표준화된 신경심리검사 도구인 벤튼 신경심리검사(Benton Neuropsychological Assessment. 이하 BNA)를 사용하여 정신분열병 환자에서 특정한 신경인지기능 결함 유형이 관찰되는지 평가하고자 하였다. 대상 및 방법 : 정신장애 진단통계편람 제4판(DSM-Ⅳ) 진단기중에 따라 분류된 (1) 편집성 정신분열병 입원 환자 30명과 (2) 연령, 성별, 교육정도를 일치시킨 정상 대조군 30명을 연구 대상으로 하여 정신분열병 환자의 임상 증상을 양성 및 음성증상척도(Positive and Negative Syndrome Scale, 이하 PANSS)로 평가하여 인지 결함과 임상 증상간의 상관관계를 검증하였다. 결 과 : BNA 12개 검사(시간지남력 검사, 좌우지남력 검사, 연속숫자학습, 얼굴재인 검사, 직선지남력판단, 시각형태변별 검사, 판토마임재인, 촉각형태지각, 손가락위치판단, 음소변별, 3차원토막구성, 운동지속력 검사)중에서 정신분열병 환자는 정상 대조군에 비해 연속숫자학습(이하 유의수준 p〈0.05), 얼굴재인 검사, 촉각형태지각, 손가락위치판단에서 통계적으로 유의하게 저하된 수행을 보였다. 또한 정신분열병 환자는 정상 대조군에 비해 손가락위치판단 하위 요인 중 오른손, 왼손, 이점역에서 저조한 수행을 보였고, 시각형태변별 검사의 주변오류에서 유의하게 많은 오류를 나타냈다. 정신분열병 환자군에서 PANSS 총점, 양성 및 음성증상척도도 점수와 각 검사, 하위 요인, 오류 점수간에는 유의한 상관관계가 나타나지 않았다. 결 론 : 정신분열병 환자군에서 임상증상과 독립적인 언어성 작동기억, 학습, 주의력 및 안면지각기술과 촉각정보처리 등 시각과 촉각 양식의 지각 과제에서 복잡한 감각정보처리의 결함을 보이며, 이러한 신경인지기능 결함 유형은 선행 연구에서 제시된 특정한 결함 유형과 최소한 부분적으로 일치되는 소견이다. 한편 정신분열병 환자가 대상 위치검사에서는 상대적으로 정상적인 수행을 보인 반면 대상 인식검사에서는 결함을 나타냈으며, 언어성 작동기억이 결함을 보인 결과는. (1) 전전두엽과 두정엽 피질간의 상호연결이나 (2) 전전두엽과 해마간의 상호연결의 기능 이상을 시사할 가능성이 있으나 후속 연구에서 확증이 필요하다. Objectives : Schizophrenic patients have been reported to be associated with abnormal performance on a broad range of neuropsychological tests. But it has been a persistent controversy in the neuropsychology of schizophrenia whether this disorder is characterized by generalized deficits or specific deficits. The purpose of this study was to investigate, using standardized Benton Neuropsychological Assessment(BNA), whether the specific pattern of neurocognitive deficits is found in schizophrenics. Methods : The subjects were composed of (1) 30 schizophrenic inpatients who were diagnosed as paranoid subtype according to DSM-Ⅳ diagnostic criterior and (2) 30 normal subjects with matching demographic variables(i. e. age, sex, educational level). All tests of BNA were given schizophrenic patients and normal subjects, and the performances of schizophrenic patients and normal subjects were compared on all aspects of BNA. Schizophrenic symptoms were assessed via Positive and Negative Syndrome Scale(PANSS) to determine the relationship between clinical symptoms and schizophrenic cognitive deficits. Results : Of 12 tests of BNA, schizophrenic patients performance on Serial Digit Learning (SDL), Facial Recognition Test(FR), Tactile Form Perception(TFP), Finger Localization(FL) were significantly lower than those of normal subjects. In addition, schizophrenic patients showed significantly lower performances than those of normal subjects on Right Hand, Left Hand, Identification of two simultaneously touched fingers of FL, and more Peripheral Error on Visual Form Perception Test(VFPT). Finally, no significant correlation was found with respect to the relationships between total scores, positive symptoms scores, negative symptoms scores of PANSS, and all scores of BNA tests in schizophrenic patients. Conclusion : These results suggest that schizophrenic patients may have a specific pattern of neurocognitive deficits in verbal working memory, learning, attention, and complex sensory information processing in visual and haptic modality such as facial perception skills, tactile information processing, independent of psychotic symptoms. The pattern of deifcits is at least in partial, in agreement with many previous study results. On the tests of linguistic functions, visuospatial perception, and constructional abilities, schizophrenic patients' performance were not significantly different from those of normal subjects. The findings on visuospatial perception and constructional abilities imply that some posterior cortical zones may be relatively uncompromised in schizophrenia. Both poor performances on object recognition tests relative to normal performances on object location tests and verbal working memory dysfunction may be associated with the putative dysfunction of the reciprocal connections either (1) between the prefrontal and parietal cortex or (2) between the prefrontal cortex and hippocampal formation. This tentative explanation remains to be confirmed.

청주지역 우수 아파트단지의 공용공간 이용도 및 만족도

박경옥,조현주 충북대학교 교육 ·생활연구소 생활과학연구센터 2002 생활과학연구논총 Vol.6 No.1

The purpose of this study is to give fundamental data for the planning on common facilities of apartments. Common facilities are consisted of green area, service facilities, children's activity space, social sports facilities, welfare facilities and leisure facilities. The apartment complexes in Cheongju city with well-designed common spaces were selected for this study, and we examined their composition of common facilities and the residents' satisfaction. 90 residents of 3 apartment complexes, which were built in last 3 years and have more than 500 households, answered the questionnaire. The result were as follows. 1) The diversity of common spaces is not sufficient, and the planning of common spaces is focused only on green spaces. 2) The pond, artificial fall, and artificial spring got high score in the use and satisfaction level, showing good planning of outer spaces. As a conclusion, inner common space planning as well as outer common space planning is very important for high quality residential environment, and operation system of these space has to be considerately designed.

감염근관에서 Black-Pigmented Bacteria의 동정에 대한 연구

권은경,김은숙,곽주석,이황,이수종,임미경 大韓齒科保存學會 2002 Restorative Dentistry & Endodontics Vol.27 No.1

Black-pigmented bacteria have been implicated in the endodontic infections. This group of microorganisms includes Porphyromonass endodontalis, Porphyromonas gingicalis, Prevotella intermedia, and Prevotella nigresceus. The organisms display a wide variety of virulence factors that may be pertinent to acute endodontic infections. The aim of this study was to identify P.endodontalis, P.gingivalis, P.intermedia, and P.nigrescens by using special potency disk test, filter paper spot test, 16S rRNA gene-directed PCR, and API 32A. Microbial samples were collected from root canals of 33 intact teeth with necrotic pulp and/or apical periodontitis. Conventional laboratory methods were used for identification of the strains of black pigmented bacteria. Eighteen of 33 samples were positive for the growth of black-pigmented bacteria. Five colonies were cultured from each pure cultured colonies from Brucella agar plate. Seventy seven colonies were positive for the growth of black-pigmented bacteria. Thirty three of 77(42.6%) were identifed as P.nigrescens, 10 of 77(12.9%) were P.gingivalis, 6 of 77(7.8%) were P.endodontalis, 10 of 77(12.9%) were P.intermedia. On the contraty the reference strains of P.nigrescens, experimental strains of P.nigrescens was sensitive to kanamycin in special potency disk test. 16S rRNA gene PCR and API test after rapid presumptative identification methods. such as special potency disk test and filter paper spot test, would be accurate detection methods for black-pigmented bacteria.

생분해성 다공질 Calcium Phosphate 세라믹스의 제조

이경주,이중환,김석영 嶺南大學校 工業技術硏究所 1995 工業技術硏究所論文集 Vol.23 No.2

When porous calcium phosphate ceramics are used as a bone graft substitute, it is known that new tissue or blood vessel is grown into the porous implant due to their excellent biocompatibility. In this study, the most chemically stable β-crystalline form of calcium metaphosphate, Ca(PO₃)₂is prepared by the controlled thermolysis of monocalcium phosphate, Ca(H₂PO₄)₂. The diameter of cylindrical pores formed during cooling was controlled by a holding time at the melting point of a monocalcium phosphate and by the change of a recrystallization temperature, to obtain the most appropriate size(about 200㎛) of pores. It was observed that the increasing holding time at the melting point of monocalcium phosphate results in the decreases of pore sizes.

赤何首鳥와 白何首鳥의 外部 및 內部形態

宋坰松,申喆均,朱榮丞 대한본초학회 2004 大韓本草學會誌 Vol.19 No.1

Objectives : This study was designed to establish a characteristic discrimination of internal and external morphological standard of original plants and herbal states in Polygoni Multiflori and Cynanchi Wilfordii Radix. Methods : In this studies, the external-internal morphological standards were determined by using stereoscope and butanol series. Results : 1. The external characteristics of original plants: Polygonum multiflorum has alternate leaves, and its flower with white color blooms at the shoot apex or leaf axil. In the other hand, Cymchum wilfor&i has opposite leaves, and its flower with yellowish green color blooms at the leaf axil. 2. The physical characteristics of herbal states: Polygoni Multiflori Radix is red-brown in outer surface, pink-brown in section. In the other hand, Cynanchi Wilfordii Radix is earthly-brown in outer surface, greyish white in section. 3. The physical characteristics according to the place of production: Demonstrable difference according to the place of production is not seen. Polygoni Multiflori Radix is brown or dark brown in outer surface, soft yellow-dark brown in section. In the other hand, Cynanchi Wilfordii Radix is white in outer surface, white-weak red in section, and has power type. 4. The internal characteristics: Pofygonum mulQt7orum has hetero-vascular bundle and lignification of cork layer is progressive. In the other hand, cynanchum wilfordii has not hetero-vascular bundle, and lignification of cork layer is weak. Conclusion : In the future, many fundamental study such as how to discriminate between Polygoni Multiflori Radix and Cynanchi Wilfordii Radix in origin and efficacy will be necessary. Also the standard of discrimination must be specific and distinct in that several kinds of fo-ti has been traded.

급성호흡부전증 환자에서 초기 인공환기방식의 중요성 : 인공환기시 혈역학적으로 유의한 부정맥의 유발요인 분석

이영주,김원,김영득,천석천,임경수 대한응급의학회 2000 대한응급의학회지 Vol.11 No.4

Background: The purpose of this article was to identify the risk factors related to development of hemodynamically significant cardiac arrythmias in patients with mechanical ventilation. Methods and Results: Holter recording and echocardiogram were performed after 30 minutes of ventilator initiation in patients on mechanical ventilation(MV) owing to respiratory failure(RF) from various reasons. From 68 patients, hemodynamically significant cardiac arrythmias were detected in 18 patients(26.5%). Initial mean arterial pressure, maximal heart rate, and initial pH were identified as risk factors for hemodynamically significant cardiac arrythmlas. Additionally, the patients with pressure-controlled ventilation as an initial ventilatory mode developed hemodynamically significant cardiac arrythmias less frequently than the patients with other modes(15.8% vs. 40%, p=0.03). In multivariate analysis, initial mean arterial pressure(<70mmHg, odds ratio[OR]: 5.5; 95% confidence interval[CI]: 1.2 to 24.2, p=0.026), maximal heart rate(>120/min, OR: 19.7; 95% CI: 2.0 to 190.9, p=0.01), and pressure-controlled ventilation(OR: 0.13, 95% CI: 0.03 to 0.55, p=0.006) were associated with the development of hemodynamically significant cardiac arrhythmias. Conclusion: Theses findings suggest that during the early stages of mechanical ventilation with acute respiratory failure, hemodynamically significant cardiac arrhythmias are directly associated with tachycardia(>120/min), initial MAP(<70 mmHg), and, inversely, the initial use of pressure-controlled ventilation.

주변성 법랑모세포종의 증례

송주섭,김경아,고광준 대한구강악안면방사선학회 2006 Imaging Science in Dentistry Vol.36 No.2

Peripheral ameloblastoma is an extremely rare odontogenic soft tissue tumor with histologic characteristics similar to those of the intraosseous ameloblastoma. It appears in the gingiva and oral mucosa. And it usually does not show any bone involvement on radiographs, except for saucer shaped erosion of underlying alveolar bone. Recurrence is considered uncommon. We report a case of peripheral ameloblastoma with bone involvement. Histologically it presented with follicles and nest of tumor cells with palisading pattern. And radiographs showed the typical saucer shaped alveolar bone erosion at the distal area of right mandibular third molar. At 6-month follow-up after operation, no local recurrence was noted.