工團 周邊 農耕地 土壤의 成分 變化에 관한 硏究

鄭大守,金度勳,金賢勍 東亞大學校 1995 東亞論叢 Vol.32 No.-

溫山工業團地 造成에 따른 土壤汚染의 정도를 調査하기 위하여 1988年부터 1994年까지 7년간에 걸쳐 工團 隣近地域의 논과 밭 土壤에 대한 土壤成分의 理化學的인 變化를 調査分析한 結果를 要約하면 다음과 같다. 土壤의 pH 變化는 논과 밭 土壤 모두 每年 pH가 약간씩 減少하여 土壤 酸性化가 深化되어지고 있으며, 一部 地域에서는 pH 5.0 以下의 强酸性을 나타내는 곳도 있었다. 논 土壤의 特性變化에서는 有機物含量과 有效燐酸의 含量은 全國平均보다 낮았으며, Ca++이온과 Mg++이온의 含量은 每年 增加하는 傾向이었다. 밭 土壤의 特性變化에서도 有機物含量과 有效燐酸의 含量은 全國平均보다 낮게 나타났으며, K이온은 全體 平均이 0.85me/100g으로 全國平均 0.5m3/100g보다도 높은 含量을 보였고, Ca++이온과 Mg++이온의 含量은 每年 增加하는 傾向을 나타내었다. A study was carried out to investigate the possibility of soil pollution in Onsan Industrial Complex. Physical and chemical properties of soil were analyzed. Soil samples were collected from paddy and upland soil around the Onsan Industrial Complex between 1988 and 1994. The results were summarized up as follows: Soil acidity of paddy and upland soil was slightly decreased every year respectively. Some sampling area and showed the strong acidity which was less than pH 5.0. For the characteristics of paddy soil, the content organic matter and phosphroic acid were lower than that of Korean average. The content of Mg ++ and Ca++ were increased by degree every year. In the case of upland, the content of organic matter and phosphoric acid showed similar pattern as low as Korean average. The content of K+ was higher as the value of 0.85me/100g comparing with the Korean average, 0.5me/100g. For the Mg++ and Ca++, the contents were also increased by degree every year, respectively.

Rat의 복강내에 투여한 5-fluorouracil-polyglycolic acid 제형이 장기에 미치는 영향에 관한 연구

강대영,송규상,최정목,노승무,정경수,오정연,김진향,양준묵,최선웅,이진호,조준식,민병무,김용백,김창식,박근성,김승영,김학용,인현빈 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

For more effective intraperitoneal chemotherapy, the authers made 5-fluorouracil-polyglycolic acid composite disks(FU-PGA disks) with 5-fluorouracil and polyglycolic acid, a biodegradable polymer. We inserted the FU-PGA disk into the peritoneal cavites of Sprague-Dawley male rats, the control and three experimental groups; one FU-PGA disk insert group(300mg/kg), two FU-PGA disk insert group(600mg/kg), and three FU-PGA disk insert group(900mg/kg). The control group received a similar number of PGA disk inserts. A pharmacokinetic study was performed to measure the 5-fluorouracil concentration in the peritoneal fluid, blood, and tissues(liver, kidney and heart) at 24 hours, 72hours and 168 hours after insertion of the FU-PGA disk. Light and electron microscopic studies were done. The results were as follows: 1) The number of white blood cells and platelets decreased after FU-PGA insertion. The degree was proportional to the duration and amounts inserted. The change in the number of red blood cells varied slightly. 2) Light microscopically, slight changes were noted at 168 hours in the 3 disk insert group (900mg/kg). Mild fatty change and hepatocyte degeneration around the central veins of the liver were noted, with vacuolar degeneration in the proximal convoluted tubules of the kidney. 3) Electron microscopically,the liver showed focal increases of lipid droplets in the hepatocytes, and irregular nuclear membrane with focal nucleolar segregation of the fibrillar and granular elements. Also the double membranous structure of the hepatocytes and Kupffer cells was widened with bleb formation. The kidney showed wide separation of the nuclear double membrane in the proximal convoluted tubular cells and mesangial cells, with vacuolation and myelin figure formation in the mitochondria of the proximal convoluted tubular cells, at 72 hours and 168 hours in the 2 to 3 FU-PGA insert groups. The heart showed focal loss of cristae,vacuolation and myelin figure formation in the mitochondria of the 2 to 3 FU-PGA insert groups. In conclusion, despite the large amont of FU-PGA inserted, the histopathological changes in the liver, kidney and heart were slight, and consonant with the very low amount of 5-fluorouracil concentrations detected in the liver, kidney and heart. The above results suggest that the FU-PGA composite can serve as a new device for releasing drugs in a controlled manner and easily targeted to intraperitoneal organs. This device can improve the efficacy of intraperitoneal chemotherapy for gastric cancer.

인삼사포닌의 마우스 비장 임파구에 대한 면역활성

정경수,이대우,양희정,이순철,김길현 충남대학교 약학대학 의약품개발연구소 1994 藥學論文集 Vol.10 No.-

To ellucidate immunologic activities of ginseng saponin, the splenic leukocytes of BALB/c mice were incubated in RPMI medium for 48hr with or without ginseng total saponin(GTS), and then analyzed flow cytometrically. Upto the concentration of 100㎍/㎖, GTS exherted stimulatory effect on the immune cells most prominently on B cells: the percentage of the surface Immunoglobulin (sIg) -positive cells (B cells) of the control was 47.l%, while that of GTS treated was 58.9%. The percentages of monoclonal antibody(mAb) J1j-reactive cells (T cells) were 28.8% and 3l.3%, those of mAb Gkl.5-reactive cells (CD4' T cells) were l8.5% and l9.l%, and those of mAb M1/70-reactive cells (mostly macrophages) were 4.4 and 5.0% at the concentration of 0 and 100㎍/㎖, respectively. However, at the concentration of 300㎍/㎖ or higher, GTS was found to be toxic to the immune cells especially to B cells in that the flow rate of the cells (gated viable cells) significantly decreased and the percentage of B cells droped from 58.9% to 31.2% and 25.4% at l00, 300, and 1000㎍/㎖, respectivelly. These data strongly suggests that GTS would exhert B-cell mitogen-like activity at physiological concentrations of 100㎍/㎖ or lower.

민어(Miichthys miiuy)의 卵發生過程 및 仔稚魚 발육단계에 따른 형태발달

한경호,오성현,황동식,조영현,서대철 한국어류학회 2002 韓國魚類學會誌 Vol.14 No.2

본 연구는 2000년 8월 19일 전라남도 신안군 임자도 연안에서 2각망으로 어획된 민어 어미를 인위적인 방법으로 수정하여 부화 사육하면서 관찰한 卵發生 過程 및 仔稚魚 형태변화는 다음과 같다. 1. 민어의 受精卵은 구형의 분리 부성난으로 알의 크기는 0.96~1.08㎜(평균 1.01㎜, n=50)였고, 크고 작은 油球가 1~5개(0.06~0.34㎜) 존재하였다. 2. 사육수온 25.2~28.4℃에서 受精 후 17시간 10분에는 배체가 卵膜을 뚫고 머리부터 孵化하기 시작하였다. 3. 孵化 직후 仔魚의 전장은 2.36~2.63㎜(평균 2.48㎜, n=10)로 전장의 45.0~47.0%에 달하는 큰 卵黃(장경 1.11~1.20㎜, 단경 0.92~0.96㎜)을 가지고 있으며 筋節은 7~8+ 17~19=24~27개였다. 4. 孵化 후 3일째 仔魚는 전장 3.98~4.32㎜(평균 4.16㎜, n=10)로 입은 열려있었고, 이 시기에 섭이활동이 활발하게 관찰되면서 卵黃이 완전히 흡수되어 後期仔魚期로 이행되었다. 5. 孵化 후 10일째 後期仔魚는 전장이 5.88~6.74㎜(평균 6.30㎜, n=10)로 꼬리의 말단이 굽어지기 시작하는 시기로 黑色素胞가 기저후두골 뒷부분의 체측에서 점모양 및 나뭇가지모양 으로 출현하였다. 6. 孵化 후 31일째 개체의 전장은 9.62~12.76㎜(평균 11.12㎜, n=10)로 모든 지느러미가 정수에 달하였고, 체형이나 반문이 成魚와 닮아 種魚期로 이행하였다. Egg development and morphological change of larvae of the brown croaker, Miichthys miiuy, were investigated after obtaining samples by artificial insemination. The spawning season extends from the middle to the end of August in the seas off Lim-ja Island, Cheollanam-do. The fertilized eggs were transparent, spherical, separate and they floated. Egg diameter ranged 0.96~1.08㎜ with several oil globules of 0.06~0.34㎜. Hatching occurred 17 hours 10 minutes after fertilization in 25.2~28.4℃ water temperature. The newly-hatched larvae were 2.36~2.63㎜(mean:2.48㎜, n=10) in total length(TL), had a large yolk, and 7~8+17~19=24~27 myotomes. Melanophores were distributed on the eye lens. Three days after hatching the larvae had attained 3.98~4.32㎜ in TL(mean:4.16㎜, n=10), the yolk sac was completely absorbed, and they had transformed into the postlarva stage. The larva reached the juvenile stage with all fins formed and with a complete set of fin rays(D.Ⅹ-28~31;A.Ⅱ-7~8;P. 21~23;C. 19~21;V. 25~26) on the 31st day after hatching. The juveniles were 9.62~12.76㎜(mean:11.12㎜, n=10) in total length. At this point the juvenile was similar to the adult in body form and pigmentation pattern.

비글개에서 신우황청심원의 급성 및 아급성독성시험

권오경,성하정,곽형일,방명주,신대희,이진영,박대규,정규혁,윤효인,조명행 성균관대학교 약학연구소 1998 成均藥硏論文集 Vol.10 No.1

Single and 4 weeks oral administration of New Woohwangchungsimwon (NWCH) which was used l-muscone as substitutive material of musk, to beagle dogs of both sexes were performed to investigate both acute and subacute toxicity. Beagle dogs(3 males and 3 females) in acute experiments were administered orally with single dose of 2,000 ㎎/㎏ and groups of 9 male and 9 female beagle dogs in subacute experiments were given daily different dosage of NWCH, 160 ㎎/㎏/day(low dosage group), 400 ㎎/㎏/day (middle dosage group), 1,000 ㎎/㎏/day (high dosage group) once a day for 4 weeks by oral route according to the Established Regulation of Korea Food and Drug Administration (1996. 4. 16). LD_50 value for beagle dogs was more than 2,000 ㎎/㎏ per oral for both male and females. In animals administered with NWCH, there were neither dead animals nor significant changes of body weights. In addition, no differences were found between control and treated groups in clinical sign, urinalysis, eye examination, hematology, serum chemistry, organ weight and other fingings. No histological lesions were observed in both control and treatment groups. Above data strongly suggset that NWCH in beagle dogs is considered to be safe.

참깨 種實의 發芽중 脂肪酸 組成의 變化에 관한 硏究

鄭大守,金度勳,丁海鎭,金賢勍 東亞大學校生命資源科學大學附設 農業資源硏究所 1995 農業生命資援硏究 Vol.4 No.1

참깨 種子를 25℃의 incubator에서 10日 동안 發芽시키면서, 發芽後 1日, 3日, 5日, 10日로 區分하여 試料를 採取하여 油脂含量과 脂肪酸組成의 變化를 比較 分析한 結果는 참깨 種子 發芽中 油脂含量의 變化는 發芽前 안산깨가 53.8%, 단백깨가 52.5% 發芽後 5日에 18.8%와 13.6%, 10日째에 9.3%와 7.3%로 減少하였다. 그리고 總脂質中의 脂肪酸 組成은 幼植物이 成長함에 따라 palmitic acid, stearic acid 및 linolenic acid는 增加하였으나, linoleic acid는 減少하는 傾向을 나타내었고, 發芽後 5日과 10日의 子葉部와 胚軸部의 脂肪酸 組成은 linolenic acid는 急激히 增加하였으나, palmitic acid, stearic acid 및 oleic acid 減少하는 傾向을 나타내었다. Sesame(Sesamum indicum L.) seeds were germinated at 25℃ for 10 days in order to investigate changes in the oil contents and fatty acid composition of total lipid. The sample for analysis was distinguished with 1st day, 3rd day, 5th day and 10th day after germination. In Ansan and Danbak varieties during the germination period, the oil contents were decreased continuously from 53.8%, 52.5% pre-germination 18.8%, 13.6% on the 5th day, and 9.3%, 7.3% on the 10th day after germination. In fatty acid composition of total lipids, palmitic acid, stearic and linolenic acid were increased, but linoleic acid showed the opposite tendency, according to the growth of seedling. In fatty acid composition of cotyledon and seedling axis, linolenic acid was increased rapidly, but palmitic acid, stearic acid and oleic acid decreasing trends showed during the germination periods.

木村腐朽菌의 菌絲生長抑制에 대한 木村 防腐劑의 效果

민경희,정대교 建國大學校 附設 農業資源開發硏究所 1993 農資源開發論集 Vol.18 No.-

한천 평판 희석법에 의한 각 방부제의 목재부후균 T. palustris와 C. versicolor에 대한 생육저해 효과는 유용성 방부제인 IF-1000과 IPBC가 효과가 가장 크게 나타났으며, 수용성방부제 중에서는 CCB가 우수하게 나타났다. 또한 T. palustris보다 C. versicolor에 대해 방부제의 생육저해 효과가 크게 나타났다. IF-1000, IPBC, ZKCF, CCA, and CCB were tested for their ability to inhibit the mycelial growth of Tyromyces palustris and Coriolus versicolor. The inhibitory effect of chemicals was measured by the length of mycelial growth. IF-1000 and IPBC showed the highest inhibitory effect for Tyromyces palustris and Corigolus versicolor, And C. versicolor was more sensitive than T. palustris in chemical treatments.

근대적 인간관에 기원한 정치사회 성격에의 재고찰 : 마키아벨리, 홉스, 로크, 루소를 중심으로

권경주,윤대식 建陽大學校 1997 建陽論叢 Vol.- No.5

Contemporary man is at the beginning of postmodernity in historical process. We must understand postmodernity and our ontological status based on the modernity. Therefore understanding and accepting of postmodern elements are limited in the present based on mosernity. Considering discourses on the human nature and political society provided by modern political thinkers who had the vision on new order and prosperity, we can understand our situation confronted with new order and have opportunities seeking some proposals to prepare.

窒素, 燐酸 및 加里의 施肥水準이 藥用作物 仙鶴草(Agrimonia pilosa L.)의 生育 및 收量에 미치는 影響

김현경,황필성,이용호,김기영,정대수 東亞大學校 大學院 2000 大學院論文集 Vol.25 No.-

This study was carried out to determine the effect of various fertilizer levels on the growth and yield of Agrimony. this experiment was conducted for 2years from 1998 to 1999 in Medicinal Plant Experiment Station, Kyungnam ARES. The results obtainned were summarized as follows : 1. The growth characteristics such as plant height, tillers and leaf numbers were more increased at 22-10-10 plot than of other fertilizer levels. 2. Variations of percent flowering of Agrimonia pilosa L. treated with different fertilizer levels were more increased at 22-10-10 plot than of other fertilizer levels. 3. Yield per 10a of Agrimonia pilosa L., Fresh weight was 1,500kg in 22-10-10 plot, and 243kg in non-treatment plot. The dry weight was 736kg in 22-10-10 plot, and 96kg in non-treatment plot. Yield of Seed and Fruit following to different application levels was highest at the fertilizing plot of N, P2O5, K2O=22-10-10.

인공모래 부산물 재활용 방안

김경남,신대용,이현종 강원대학교 부설 석재복합신소재 제품연구센터 2002 석재연 논문집 Vol.7 No.-

인공모래 제조시 부산물로 발생하는 석분슬러지에 의한 환경문제와 폐기되는 자원의 활용문제를 해결하기 위하여 석분슬러지와 점토 및 폐유리분말을 이용하여 900∼1,100℃로 소성하여 세라믹스 건자재를 제조하였다. 석분 슬러지는 평균입경 16.3㎛, 비표면적 0.42㎡/g, 화학조성은 CaO 46.43wt%, SiO_2, MgO 와 Al_2O_3가 7.83 wt% , 6.17 wt% 및 3.13 wt%이며, 주결정상은 calcite (CaCO_3)와 dolomite (CaMg(CO_3)_2)로서 약 800℃에서 CaCO_3나 CaMg(CO_3)_2의 열분해에 의한 32.52wt% 의 강열감량을 나타내었다. 석분슬러지와 점토를 이용한 시편(No. 1, 4, 7, 10 및 13)은 점토의 첨가량과 소성온도가 증가함에 따라 시편의 부피비중 및 압축강도는 증가하였으나 기공률과 흡수율은 감소하여 No. 1, 4, 및 7 시편은 부피비중 1.78∼1.98, 기공률 6.4∼12.5%, 흡수율 10.3∼12.7%, 압축강도 264∼370kgf/㎠을 나타내었다. 폐유리분말을 첨가한 시편(No. 2, 5, 6, 8, 9, 10 및 12)의 부피비중과 압축강도는 1.91∼2.63 및 213∼895kgf/㎠로서 폐유리분말의 첨가가 시편의 소결성과 압축강도의 향상에 기여하여 세라믹스 건자재로 사용이 가능하였다. The utilization of waste stone powder sludge produced secondarily from artificial sand plants of Ssangyoung resource development (Co.) and general waste, as was classified, became very important to solve the environmental problem and waste materials recycle. In the chemical composition of stone powder sludge, the amount of CaO was 46.43wt%, SiO_2, MgO and Al_2O_3 were 7.83 wt% 6.17 wt% and 3.13 wt%, respectively. The mean average particle size was 16.3㎛ and specific surface area was 0.42㎡/g. Main crystal phases were calcite (CaCO_3) and dolomite (CaMg(CO_3)_2) and ignition loss was 32.52wt% because of decomposition of CaCO_3 or CaMg(CO_3)_2. Specimens were fabricated by mixing the waste stone powder sludge, low-grade clay, waste glass powder and sintering at 900∼1,100℃ for 2 hours. The density and compressive strength of specimen increased with increasing the sintering temperature and the amount of clay. The specimen showed the bulk density of 1.78∼1.98, porosity of 6.4∼12.5%, water absorption 10.3∼12.7% and compressive strength of 264∼370 kgf/㎠. Those of the specimen heated at 1,050℃ increased with increasing the added amount of waste glass powder, bulk density was 1.91∼2.63 and compressive strength was 213∼895 kgf/㎠. Therefore, the waste stone powder sludge can be used as a constructional materials.