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        일렬 자가조혈모세포이식을 받은 다발성 골수종 환자에서 발생한 뇌 톡소포자충증 1례

        김계형,송경호,전재현,박완범,박상원,김홍빈,김남중,김인호,오명돈 대한감염학회 2010 감염과 화학요법 Vol.42 No.3

        Toxoplasmosis is a rare but fatal complication in hematopoietic stem cell transplant recipients, usually associated with allogeneic hematopoietic stem cell transplantation (HSCT). We report a case of cerebral toxoplasmosis in a patient with multiple myeloma, following tandem autologous stem cell transplantation. A 55-year-old Korean male presented with weakness in both legs that had progressed to both arms. A magnetic resonance imaging scan of the brain revealed multiple, variablesized ring-enhancing lesions with surrounding edema in the cerebral hemispheres and brain stem. Stereotactic biopsy revealed bradyzoites of Toxoplasma gondii in the brain tissue. The patient received trimethoprim-sulfamethoxazole, followed by pyrimethamine and sulfadiazine, accompanying treatment for progressive multiple myeloma. Cerebral toxoplasmosis should be considered as one of the differential diagnoses in patients with neurologic signs following autologous HSCT.

      • 笠岩山의 高等菌類相

        魏啓聞,蔡正基,鄭南澈,吳光仁 全南大學校 農業科學技術硏究所 1993 農業科學技術硏究 Vol.28 No.-

        총 2아문(Basidiomycotina, Ascomycotina) 9목 29과 77종의 고등균류가 입암산에 위치한 전남대학교 장성지방연습림에서 발견되었다. 그중 Basidiomycetes는 23과 66종으로 부후성이 30종, 균근성이 36종이었다. 부후성 버섯 중 16종(53%)이 식용가능했고 Polyporaceae(구멍장이버섯)의 버섯이 우세하였다. 균근성 버섯은 Tricholomataceae, Russulaceae, Boletaceae, Strobilomycetaceae가 23종(64%)를 차지했으며, 특히 Tricholomataceae의 Laccaria속, Russulaceae의 Russula속이 발견되었다. 본 조사지에서는 갓의 직경이 20-30㎝ 가량으로 대형인 Boletaceae의 Tylopilus neofelleus(제주쓴맛그물버섯)이 다수 발생한 것이 가장 큰 특징이었다. Ascomycetes는 6과 11종으로 부후성이 8종, 기생성이 3종이었다. 부후성 버섯은 4종이 식용가능 했으며, 4종은 약한 독성이 있는 것이었다. 기생성 버섯은 Clavicipitaceae의 Cordyceps속(동충하초속)의 버섯이 3종 발견되었다. The 9 orders, 29 families, 51 genera, and 77 species of higher fungi belong to the two subdivisions(Basidiomycotina, Ascomycotina) were collected from the Jangsung Forests of Chonnam National University Forests around Mt. Ipan. The 23 families and 66 species of basidiomycetes in which the 30 and 36 species of saprophytic and mycorrhizal mushrooms were included respectively, were isolated. The 16 species (53%) from the 30 species of saprophytic mushrooms were edible and the dominant family was Polyporaceae. The Tricholomataceae, Russulaceae, Boletaceae and Strobilomytaceae formed the 64% of the 36 species of mycorrhizal mushrooms. Of these, the Laccaria(Tricholomataceae) and Russula (Russulaceae) were common genera of which 22 species(61%) were edible and two species were very poisonous. Especially, Tylopilus neofellus(Boletaceae) that has a big fruiting body of which cap diameter is around 20-30㎝, were grown up in this area. Ascomycetes were composed of 6 family 11 species in which 8 and 3 species of saprophytic and parasitic mushrooms were included, respectively. Of the 8 species of parasitic mushrooms, 4 were edible but the other 4 were weakly poisonous. The 3 species of parasitic mushrooms were belonged to the genus Cordyceps(Clavicipitaceae).

      • 함질소 유기화합물의 초임계수 산화반응

        박계성,박성배,남영우 崇實大學校 生産技術硏究所 1996 論文集 Vol.26 No.2

        Diethylaniline and benzidine, the nitrogen containing organic chemicals, decomposed by supercritical water oxidation. The experiments were performed at temperature range between 380℃ and 448℃ in batch reactor. Oxygen was used as oxidant. Reaction orders for each reactants were determined by differential method. Activation energy and frequency factor were obtained by SAS SLIN procedure. The rate equations obtained were as follows. Rate equation for diethylaniline: ?? Rate equation for benzidine: ??

      • 풍력발전의 설비이용율 특성연구

        이계주,이은학,김유남 한라대학교 2009 論文集 Vol.12 No.-

        The scheme described checking the change transition for annual average plant factor month and season respectively as standard with measuring power exchange on Korea Power Exchange (KPX) from 2003 to 2006 and analysis of characteristic of output of wind power on a huge Wind Power Plant Complex which is selected for evaluating capacity of wind pover The result of the change transition for annual average plant factor will carry out good place construction plan and Long-term Electric Power Development Plan It can find that Wind Energy will be very useful when comparison between the value of data for long-term operating of wind power and the value of data for real wind

      • 아음속풍동의 제작과 난류경계층 구조의 변화에 관한 연구

        李南榮,朴桂香,柳相信 한국항공대학교 1991 論文集 Vol.29 No.-

        본 연구에서는 풍동의 활용성과 경제성, 장비설치 및 취급의 용이성등을 고려하여 요구풍속을 결정한 후 확산부, 정체실, 수축부, 시험부등을 설계하고, 제작된 풍동에 대한 성능검사를 실시하였다. 정체부와 시험부 수축비는 9이고 시험부의 단면은 406mm×406mm 이며 길이는 1,200mm 이다. 시험부에서 얻을 수 있는 최대속도는 송풍기 회전수 1,500rpm 일때 36m/sec이다. 송풍기 동력은 19kW 이며 송풍기 형태는 원심형 임펠러를 선택하였다. 시험부의 성능을 검사하기 위해 열선유속계를 사용하여 시험부 출구 단면에서의 속도분포와 난류강도를 조사하였다. 시험부의 속도는 5m/sec 에서 30m/sec 까지의 범위에서 난류강도는 0.5%이고 벽면경계층 두께를 고려하면 유효 단면적은 약 85%이다. 제작된 풍동에 에머리 페이퍼(emery paper) 또는 트리핑 와이어(tripping wire)를 부착한 매끈한 평판과 축대칭 3차원 물체를 장치하여 경계층 속의 흐름이 난류가 되도록 하였고 발생된 난류 경계층의 특성을 분석 하였다. In the present experimental study, the range of wind speed at the test section was determined by considering the availability, economy, installation and handling of the wind tunnel, and diffuser section, settling chamber, contraction section and test section of the wind tunnel were designed and manufactured to satisfy the prescribed wind speed range. Performance of the manufactured wind tunnel was tested according to the normal testing procedure. Contraction ratio of the test section to the settling chamber is 9 and the cross section of the test section is 406mm×406mm and the test section is 1200mm long. The maximum air speed at the test section is 36m/sec for the motor speed of 1500 rpm. A centrifugal type fan is used and the maximum power required is 19kw. The hot-wire anemometer system was employed to test the performance of the wind tunnel by measuring the velocity distribution and turbulent intensity at the exit of the test section. Measured values of turbulent intensity were less than 0.5% for the range of wind speed from 5m/sec to 30m/sec. The available cross sectional area of the test section was about 85%. Flat plate and axisymmetric three dimensional body were used as models to identify the boundary layer characteristics. The boundary layers were triggered by emery paper and/or tripping wire. The characteristics of the generated turbulent boundary layers were analyzed.

      • Paclitaxel 및 Apo-2L/TRAIL이 자궁경부암 세포주 아포토시스에 미치는 영향

        김주영,남계현,김태희,이권해,이해혁,배동한 순천향의학연구소 2003 Journal of Soonchunhyang Medical Science Vol.9 No.2

        Objective: TRAIL(also called Apo-2L) is a member of the tumor necrosis factor(TNF) family of cytokines which induces apoptosis cell death in a variety of tumor cell lines. It mediates its apoptotic effects through one of two receptors, DR4 and DR5, which are members of the TNF receptor family, and whose cytoplasmic regions contain death domains. TNF and Fas ligand induces apoptosis in tumor cells; however, their severe toxicity toward normal tissues hampers their application to cancer therapy. We examed if paclitaxed and/or Apo-2LTRAIL induces apoptosis of cervical cancer HeLa, SiHa, ME-180, and CaSki cells. Mehods : We have demonstrated that paclitaxel and Apo-2L/TRAIL induces apoptosis of cervical cancer HeLa, SiHa, CaSki and ME-180 cell lines in a dose-dependent manner. HeLa, SiHa, ME-180 and CaSki were obtained from American Type Culture Colection. Recombinant Human TRAIL(Chmicon). DR4 and DR5 were purchased from Santa Cruz. Paclitaxel, MTT assay Kit, Acridine orange and Ethium bormide were purchased from Sigma. HeLa and SiHa were grown in DMEM. ME-180 and CaSki were grown in RPMI. Tripan blue stain and MTT assay were done for cytotoxicity. Annexin V-FITC and PI(propidium iodide) flowcytometry for apoptosis assay. DR4 and DR% were expressed by Western Blot. Fluorescent Microscopy used Acridine orange(AO) and Ethium bromide(EB). Results : Importantly, concurrent treatment of cervical cancer cells with paclitaxed and Apo-2L/TRAIL induces significantly more apoptosis than Apo-2L/TRAIL alone. Conclusion : We need further studies which reveals possible therapeutic potential in the women with cervical cancer by suing Apo-2L/TRAIL.

      • 원발성 난소 소세포암 2례

        조인숙,남계현,김태희,김정식,이해혁,이권해,권계원 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

        Two cases of primary small cell carcinoma of the ovary occurred. One was a case of 43-year-old woman associated with hypercalcemia and the other was a case of 40-year-old woman with pulmonary type. Ovarian small cell carcinoma of the hypercalcemic type have clinicopathological, immunohistochemical, ultrastructural, and flow cytometric features that from differ from those of small cell carcinomas of the pulmonary type. It is important for therapeutic reasons to distinguish these two types of ovarian tumors from each other and from a variety of malignant small cell tumors that ovary primarily or secondarily. So, we reported these cases with a brief review of the concerned literatures.

      • KCI우수등재

        재래시장에서의 접근성과 업종별 상관관계 : 광주광역시 대인시장과 남광주시장을 중심으로 Focused on Daein and Namgwangju markets in Gwangju

        정금호,이계순,신남수 대한건축학회 2004 대한건축학회논문집 Vol.20 No.1

        The conventional market places are the behavioral space by physical environment and human activity. We discuss ways and means of reviatalizing conventional market. Focused on consumer's aspect and physical improvement of building and equipment. In spite of it's small size, small area. Market is directly connected with daily life of citizen and plays a major role for urban activities and systems. Therefore is necessary to study the physical characteristics related to human activity for improving the physical environment of conventional market. This study base on an assumption that location of industrial classification depend on accessibility and relation with street. The purpose of this study is to analyze relation between street and industrial classification in conventional markets. For the logistic analysis, We investigated type of business, general road width, public land price, connection value, distance from a bus stop, distance between main street and the each store in Daein and Namgwangju markets. The statistical analysis says that 1. In the markets, food stores are located near from the main streets. 2. Clothing stores are located near from the main streets but far from the bus stops. 3. The culture type of business is located far from the main streets. 4. The neighboring facilities are located on the narrow roads and at the lands high in the public price.

      • 비정질 Se_90Sb_10 박막의 결정화에 관한 연구

        金太晩,李啓南 慶熙大學校 1989 論文集 Vol.18 No.-

        The change of the dc conductivity during the isothermal annealing of Se_90Sb_10 film with time was studied at 60, 70 and 80℃. The change of the conductivity as a function of time was used as the characteristic quantity of amorphous-crystal transition. The Avrami equation which is represented with the change of log conductivity was applied to expain the process of crystallization of samples, and values of different parameters for the crystallization were evaluated. X-ray diffraction records of samples were used to study the same process. Evaluated values of Avrami exponent of samples were close to 2 or 1, which correspond to the one dimensional growing process. Rate constants k were 2.67 × 10 exp (-4), 1.02 × 10 exp (-3) and 2.22 × 10 exp (-3) for samples annealed at 60, 70 and 80℃, respectively. The activation energy of the crystallization, E, was 2.47 kcal/mole. And then dependence of the radius R of the spherulite crystalline domain on the time, and of the time rate of crystallization, ν, on R were understood.

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