대장암환자에서 자연살해세포의 변화

김광호,심강섭,박응범,강은숙,홍기숙 대한대장항문학회 1998 Annals of Coloproctolgy Vol.14 No.3

근로자 건강증진전략을 위한 행동변화에 대한 요구도 평가

이강숙,임현우,구정완,홍현숙,이정민,이원철,박정일,맹광호,M, O'Donnel 大韓産業醫學會 1999 대한직업환경의학회지 Vol.11 No.4

Objectives : In order to evaluate the stage of behavior change for health promotion strategy in workplace Methods : Questionnaire survey was carried out for 309 workers who employed in H Electronics company in Kyong-in area from September to October 1998. Results : According to need assessment of four step such as precontemplation stage, contemplation stage, action stage, maintenance stage which were to change of behavior for health promotion, the percent for quitting smoking were observed 48.8%, 43.1%, 8.1%, 0%, and for the restriction of drinking were 29.8%, 10.6%, 9.3%, 5.3%; for fitness 11.1%, 31.0%, 37.3%, 20.6% in male 26.6%, 27.8%, 26.6%, 19.0% in female, for regular diet 26.1%, 19.8%, 38.7%, 15.3% in male, 27.8%, 22.2%, 40.0%, 10.0% in female and for stress management 5.8%, 10.6%, 8.7%, 75.0% in male, 13.6%, 22.7%, 19.7%, 44.0% in female. In heavy smoker(p=0.017) and heavy drinker,(p=0.021) the percent of precontemplation stage was significantly higher than in lower drinker and light smoker. Conclusions : This study suggested that company support for health promotion in workplace was and workers of high risk group for smoking and drinking were in precontemplation stage. So before conducting the health promotion program, health risk appraisal and need assessment for stage of behavior change should be taken for the efficient health promotion strategy.

사무공간의 통합유니트 구축을 위한 조명유니트 도출에 관한 연구

김선숙,신선준,김지현,양인호,김광우 대한건축학회 2005 대한건축학회논문집 Vol.21 No.1

The purpose of this study is to develop the lighting units for workspace and to propose their application method at the architectural design stage The lighting unit is one of the components of a workspace integrated unit, which can be defined as the planning unit satisfying the environmental comfort criteria of workspace According to the survey of current domestic and foreign office buildings, the luminaire layout types could be classified into the line, spot and square type Various simulation cases were set up considering these layout types, architectural modules, and luminaire types Finally, forty-four lighting units were developed by RADIANCE simulation With these lighting units, the designer would be able to easily predict how his decision about architectural modules influences the lighting design, and can consider other alternatives

우울증 환자의 혈당에 관한 연구

고희숙,김광일 大韓神經精神醫學會 1980 신경정신의학 Vol.19 No.3

In the biochemical study of depression, research interest has been focused mainly on the metabolism of neurotransmitters. Meanwhile, several researchers have paid attention to the blood sugar change in depression. Pryce (1958), van-Praag(1965), Muller, Heninger & McDonald(1969) and Diebold(1976) proved that blood sugar level was increased during active phase of depression and decreased by recovery, while, Herzberg, Coppen & Marks(1968) reported opposite result. The authors have tried to confirm the changes of blood sugar in depression with special regard to patterns of the changes in diagnostic subgroups of depression. Fifty six in-patients were initially selected for the study. But out of 56 subjeets, 22 were discarded; 12 subjects were lost because of their early discharge, two cass of thyroid dysfunction, two of diabetes mellitus and 6 with history of antidepressant medication previously at the out-patient clinic were excluded in this study. Among 34 subjects, 16 were retarded depression, 5 were agitated depression and 13 were secondary depreesion which was observed in borderline and hysterical personality disorders and recovered schizophrenia. Fasting blood sugar level was checked on the first, third, fifth days of admission, then weekly basis till fifth week. Hamilton's Rationg Scale for depression was used in symptom evaluation on the days of blood sampling. Fasting blood sugar level of retarded depression was higher than that of secondary depression. However, this increase was within normal limit. On the other, two subgroups could be identified according to the pattern of blood sugar level; typical and atypical groups. Typical group was a state in which manifested increased FBS level in the initial phase of treatment then slow decrease as symptom improvement. Atypical group was a state in which manifested irregular FBS level on the course of illness without initial increase. Fifty percent of retarded depression, 20 percent of agitated depression, and 15.4 percent of secondary depression were the typical group. The amount of food intake revealed no difference between the typical and atypical groups. According to factor analysis of Hamilton's rating scale, factor Ⅰ, Insomnia, was more prominent in typical group and factor Ⅴ, Somatic Delusion, in atypical group. Symptom improvement was faster in typical group for 6 days than atypical group. Tricyclic antidepressant and phenothiazine seemed to have no effect on the FBS level. In the typical group, the increased FBS decreased gradually and maintained steady level in one to two weeks, and symptom improvement was followed six to thirteen days later.

수종의 암세포주의 저선량 방사선감수성에 관한 실험적 연구

김민숙,고광준 大韓口腔顎顔面 放射線學會 1994 Imaging Science in Dentistry Vol.24 No.2

The purpose of this study was to aid in the radiation therapy of head an neck cancer patients. For this study, radiation survival curves were generated for B16, MG063 and YAC-1 cell lines using semiautomated MTT assay and Dye Exclusion Assay. Irradiation of 2, 4, 6, 8, 10Gy were delivered at room temperature at a dose rate of 210.2cGy/min using ??Co r-ray Irradiator ALDORADO 8. The viable cells were determined for each radiation dose and compared to control values. The obtained results were as follows: 1.There was significantly different absorbance at 10Gy on B16 cell line in MTT assay(P<0.05). 2.There was significantly different absorbance at 4, 6, 8, 10Gy on MG-63 cell line in MTT assay(P<0.05). 3.YAC-1 cell line was more sensitive than B16 or MG-63 cell line to all doses of radiation(P<0.05). 4.There was significantly different absorbance among all tumor cell lines except between B16 and MG-63 cell line at 2Gy in MTT assay(P<0.05). 5.Good correlation was obtained between MTT assay and DEA(P<0.05). The efficient of correlation of B16, MG-63 and YAC-1 cell line was 0.845, 0.824 and 0.906, respectively.

대한제국 법어학교에 관한 연구

이광숙 서울대학교 언어교육원 2012 語學硏究 Vol.48 No.1

The French Language School of the Korean Empire was established in 1895 and lasted until 1911. The development of the French School occurred in three stages, like the development of five other foreign language schools (English, Japanese, Chinese, German and Russian language schools) in the Empire. During the first stage (1895-1906), the French School was the third most prosperous school, after the English and Japanese schools. A large number of students entered the School, and the employment rates of its students were high. This is because the strong diplomatic power of France during this period leads to the introduction of the French system in areas such as the government’s postal services and construction and the hiring of professionals who can speak French. The classes were held at the house of Emile Martel, a teacher at the French School, before the School found a site. Lee Nung- Hwa was a talented Korean instructor at the School, who also served as the principal. The curriculum of the School was divided into two: the language acquisition classes, which accounted for more than 60 percent, and the other subjects (history, geography, science and mathematics). The second stage of the development (1906-1098) saw the increasing influence of the Japanese government. During the third stage (1908-1911), all the foreign language schools were merged to form one school, where the French School became the Department of French Language. Japanese language is included in the curriculum of each department as an elective course during this period.

당뇨병과 동반된 화농성 간농양의 임상상 및 예후인자

오은숙,강무일,이원영,오기원,임동준,이소영,이정민,고승현,김성래,안유배,손현식,윤건호,차봉연,이광우,손호영,강성구 대한당뇨병학회 2000 임상당뇨병 Vol.1 No.1

연구배경: 감염질환은 혈관질환과 함께 당뇨병의 중요한 사망원인의 하나이며, 혈당조절이 불량할수록 감염 빈도가 증가됨은 잘 알려져 있다. 간농양의 발생이 있어서도 당뇨병은 중요한 기저질환 중의 하나이다. 일반적으로 간농양의 가장 흔한 원인균은 Escherichi coli라고 알려져 있으나, 최근 당뇨병을 가진 간농양 환자에서 Klesiella pneumoniae의 검출이 증가되고 있다. 또 최근 연구에 의하면 K.pneumonie가 간농양의 가장 흔한 원인균이며, K. pneumoniae에 의한 간농양은 K.pneumoniae 이외의 균주에 의한 간농양보다 당뇨병과 밀접히 관련되어 있다고 보고된 바 있다. 이에 저자들은 간농양 환자를 대상으로 당뇨병환자의 빈도를 알아보고, 그 원인균 및 특징을 비당뇨병 환자들의 경우와 비교해 보고자 하였다. 방법: 1992년 1월부터 1999년 6월까지 방사선학적 검사 혹은 수술에 의해 간농양이 확인되거나, 경피적 천자나 수술을 통한 배농액 배양, 혹은 혈액 검사에서 원인균이 증명된 182명의 환자를 대상으로 후향적 임상고찰을 실시하였다. 결과: 화농성 농양을 가진 167명의 환자(남:94명, 여:73명)중 당뇨병을 가진 환자는 54명 (남:30명, 여:24명)으로 32.3%를 차지하였다. 환자의 평균나이는 당뇨군에서 62.1 ± 13.4세, 비당뇨군에서는 55.1 ±15.5세로 당뇨군에서 높았으며(p=0.0021), 남녀간의 평균나이 비교 시 두 군 모두 여성의 나이가 의미있게 높았다. 비당뇨군에 비하여 당뇨군의 경우 저알부민혈증의 빈도와 aspartate transaminase가 증가되어있었다. 원인균주는 K. pneumoniae (당뇨군54%, 비당뇨군 39.1%), E. coli(당뇨군 17.5%, 비당뇨군 18.8%), Pseudomonas aeruginosa, Streptococcus viridans, Enterococcus 순이었으며 두 군간의 의미는 차이는 없었으나 K. pneumoniae의 경우 다른 균종에 비해 단독감염의 빈도가 높았다(82.8%). 사망률은 당뇨군에서 16.7%, 비당뇨군에서 7.1%로 당뇨군에서 의미있게 높았으며(p=0.019), 당뇨군에서의 사망환자는 모두 패혈증이 동반되어 있었다. 당뇨환자의 사망군은 생존군에 비해 당뇨병 이환기간이 길고 혼합감염의 빈도가 높았다(p=0.046). 검사실 소견에서는 총 빌리루빈 및 알카리성 포스파타제의 증가가 관찰되어 있었다. 결론: E. coli가 간농양의 주된 원인균이라는 기존 보고와는 달리 당뇨군과 비당뇨군 모두 K. pneumoniae가 간농양의 주된 원인균이었다. 또한 당뇨 유병기간이 길고 당뇨조절이 불량한 환자에서 혼합감염이며 총 빌리루빈 및 알카리성 포스파타제의 증가등과 같은 위험인자가 존재할 경우 사망률이 증가될 수 있으므로 이들 군에서는 적극적인 치료가 필요할 것으로 사료된다. Background: Liver abscesses are commonly associated with underlying disease, particularly diabete mellitus. The number of the liver abscesses caused by Klebslella pneumoniae in diabetic patient has been increased in Korea nowadays. This study was conducted to clarify the clinical presentation and prognostic factors of pyogenic liver abscesses, especially in diabetic patients and to determine the proportion of K. pneunomiae as a pathogen in liver abscess in Korea. Methods: Medical records of 167 patients treated for pyogenic liver abscess from January, 1992 through June, 1999 were reviewed retrospectively in detail. Major Pathogenic organism, clinical manifestations, prognostic factors, the importance of diabetes mellilus as an underlying disease and its effect on clinical features and prognosis were analyzed. Results: Among 167 cases of pyogenic liver abscess, underlying diabetes mellitus was present in 32.3%. The mean age of patients was 62.7 13.4 years in diabetic liver abscess group and 55.1 15.5 years in non-diabetic liver abscess group. Most liver abscesses were cryptogenic in origin or secondary to the billary tree diseases. The clinical presentations among the two groups were not significantly different. When compared to patients without diabetes, patients with diabetes had significantly higher proportions of hypoalbuminemia and elevated aspartate transaminase level. The most common organism of the pyogenic abscess was K. pneumoniae in both groups. Percutaneous drainage of the abscess with appropriate antibiotics was the most commonly used therapeutic modality in liver abscess. The mortality rate of diabetic liver abscess is 16.1 % and 7.1% in nondiabetic liver abscess. Complications, especially septicemla, were found more frequently in patients with diabetes than in patients without diabetes (64.8% vs 28.3%, septicemia : 31.5% vs 9.7%). The factors influencing mortality in the diabetic liver abscess were disease duration, mixed infection, presence of septicemia, elevated bilirubin and alkaline phosphatase. Conclusions: In contrast to prior report that the E. coli was the most common pathogen in liver abscess, we found that K. pneumoniae was the most common organism cultured in liver abscess. Diabetic patients have more complications and higher mortality than patients without diabetes. Early detection and proper treatment are needed to improve the outcome for diabetic patient with liver abscess.

하악전돌증 환자의 하악운동에 관한 연구

김기숙,김광남 대한두개하악장애학회 1991 대한두개하악장애학회지 Vol.3 No.1

It is important to harmonize the occlusion with TMJ and neuromuscular system. However, clinically, how to harmonize is very difficult. The mandibular movement is the motion in which all component part of stomatognathic system participate. This study was performed to compare mandibular movement of mandibular prognathic patients group with that of normal group, to ascertain which components of mandibular movement have differences between two groups, and to use for occlusal treatment of mandibular movement. Thirteen adult who have physiologically normal occlusion and are free of TMJ dysfunction were selected as a control group(Group l). Eight adult who are mandibular prognathic patient and have more than four anterior teeth crossbite, therefore have not anterior guidance function and have posterior interference at protrusion were selected as a experimental group(Group 2). Electronic pantograph, Denar Pantronic (Denar Corp., U.S.A.), was used to record mandibular movement. Pantronic survey was performed by using an arbitrary hinge axis according to manufacturer's direction. Of the Pantronic recordings, immediate side shift (ISS), progressive side shift (PSS), orbiting condylar path (ORB), protrusive condylar path (PRO) between two groups were compared and analysed. The results were as follows: 1. The average protrusive and orbiting condylar inclination of mandibular prognathic patient(28.44˚, 36.94˚) was significantly lower than those of normal group(40.15˚, 48.00˚) (P<0.01). 2. There was no statistically significant difference between the average immediate and progressive side shift of mandibular prognathic patient (0.37㎜, 6.19˚)and those of normal group(0.52㎜, 5.96˚) (P>0.0l). 3. The significant correlation was found between orbiting condylar inclination and protrusive condylar inclination.

社會階層과 作名

李光淑 서울대학교 어학연구소 1981 語學硏究 Vol.17 No.1

Das Ziel der vorliegenden Arbeit ist, die Namengebung in Heidelberg seit 1960 in zwei ausgewa"hlten Jahren (1961 und 1976) empirisch zu untersuchen. Das besondere Augenmerk der Arbeit ist dabei auf das interdependente Verha"ltnis von Name und Namengeber und deren gesellschaftlicher bzw. beruflicher Stellung gerichtet. Dabei soll im einzelnen u"berpru"ft werden, ob und inwieweit sich die Namengebung innerhalb dieses Zeitraums vera"ndert hat. Um die Abha"ngigkeit zwischen der Namenwahl und der sozialen Stellung der Namengeber zu erfassen, werden die Namengeber in bestimmte Gruppen eingeteilt. Fu"r die Einteilung wird das Schichtenmodell von Moore und Kleinig verwendet, das auf dem Merkmal 'stellung im Beruf' aufbaute. Das eindimensionale Modell ist fu"r die Untersuchung besonders geeignet, weil das Untersuchungsmaterial Angaben zum Beruf entha"lt, aber nicht zur sonstigen Stellung. Die Untersuchung der Namengebung beider Jahrga"nge zeigt, daß erkennbare Vera"nderungen bei der Namengebung in Heidelberg zwischen 1961 und 1976 eingetreten sind, und zwar einmail bezu"glich des Verha"ltnisses von Jungen-und Ma"dchennamen und zum anderen bezu"glich der Verteilungen in den verschiedenen sozialen Schichten. Der Wandel der Namengebung kommt sowohl bei der Ha"ufigkeits-wie auch bei der Gesamtverteilung der Namen zum Ausdruck. In der Ha"ufigkeitsverteilung tritt besonders im Namenschatz, bei den Prozentanteilen und bei der Herkunft der ha"ufigsten Jungen-und Ma"dchennamen eine starke Vera¨nderung auf. In der Gesamtverteilung gibt es gro"ßere verschiebungen bei der Herkunft, bei den Kurzformen und bei den nur einmal vergebenen Jungen- und Ma"dchennamen. Es wurde dabei festgestellt, daß shoche Vera''nderungen (trotz der a"ußerlich uneinheitlichen Erscheinungsformen) eine u"berregional erkennbare Tendenz der heutigen Namengebung aufweisen. Die untersuchung besta"tigt die Auffassung, daß die Namengebung auch heute noch schichtenspezifisch gepra"gt ist. Der Namengeber ist heute nicht als Mitgleid eines hierarchischen Sta''ndesystems anzusehen, sondern als Mitglied von Gruppen, mit denen er Gemeinsamkeiten in der Mentalita"t und im Selbstbewußtsein hat und an deren Erwartungsnormen er sich auch bei der Namenwahl orientiert.

유아 무용 교육이 유아의 긍정적 자아개념에 미치는 영향

이광욱,조연숙,정일호,강성환 한국스포츠리서치 2003 한국 스포츠 리서치 Vol.14 No.4

The purpose of this study was to examine through 24weeks whether dance education with 6-year old preschool-Kindergarten may increase positive self-concepts. The results of analysis of self-concept's change that the dance education served K kindergarten and not in the S kindergarten in Seoul were as follows. 1. There is a statistically significant relation of the generally satisfactory self-concepts between the two preschool-Kindergarten groups(P<0.05). It means that the development of satisfactory self-concepts are generally influenced by dance education programs. 2. There was no statistically significant relation of the same-aged children's self-concepts between the two preschool-Kindergarten groups (P>0.05). It means that the same-age children's self-concepts are not influenced effectively by dance education programs. 3. There was no statistically significant relation of the children's self-concepts about their teachers and kindergartens between the preschool-Kindergarten groups(P<0.05). It means that their teachers and kindergartens the children's self-concepts are not influenced effectively by dance education programs. 4. There was no statistically significant relation of the children's self-concepts about their classes between the two preschool-Kindergarten groups(P<0.05). It means that the children's self-concepts about their classes are not influenced by dance education programs. 5. There was no statistically significant relation of the children's self-concepts about their physical exercises between the two preschool-Kindergarten groups(P<0.05). It means that the children's self-concepts about their physical exercises are not influenced by dance education programs.