뇌동맥류 환자의 임상분석

강삼석,박중욱,류재광,신동철,김봉환 全南大醫大 1983 전남의대학술지 Vol.20 No.1

Helicobacter pylori 와 대장의 신생물과의 연관성

안중욱,류재현,김광호,박응범 대한대장항문학회 2001 Annals of Coloproctolgy Vol.17 No.3

안면부 기저상피세포암의 인접표피에서 p53 발현 양상에 관한 연구

김광진,김대중,김재훈 순천향의학연구소 1999 Journal of Soonchunhyang Medical Science Vol.5 No.1

The tumor suppressor gene, p53, has proved to be one of the genes most often modified in human cancers. These aterations consist mainly of point mutations located in the evolutionarily conserved sequences which render the protein inactive for its normal biologic functions. Many mutations of p53 result in a protein product that is abnormally stable, so it becomes readily detectable by immunochemistry. Immunohistochemical overexpression of p53 has been observed not only invasive tumors but also in precancerous or early lesions of tumors of the skin. Overexpression of p53 might be useful marker to identify precursor lesions of cancers arising de novo, which are histopathologically indistinguishable from normal cell. We were studied the p53 expressions immunohistochemically to identify a precursor lesion of basal cell carcinoma in the epidermis adjacent to basal cell carcinoma. With anti-p53 antibodies of DO7, p53 expression was frequently detected in the epidermis adjacent to basal cell carcinomas arising on the face and in the normal epidermis with usual sun exposure. In the epidermis adjacent to basal cell carcinoma, stained cells were occasionally clustered in a small area, but no cluster was found in the normal epidermis with usual sun exposure. The expression was less frequent in the normal epidermis with rare sun exposure. We have carried our PCR-sequencing of exon 5-8 of the p53 gene in 7 basal cell carcinoma and two normal epidermis with immunohistochemically positive and cluster formed. Heterozygous mutations were detected in 4 of 7 (57%) samples investigated. All mutations were G:C-A:T transitions, three at codon 248 and one at codon 273. But no mutation was detected in two normal epidermis with cluster formed positive staining. We conclude that 1. Because all basal cell carcinoma specimens examined here were obtained from facial lesions that were usually exposed to sunlight, the frequent p53 overexpression-detected in the epidermis adjacent to basal cell carcinoma might be related to chronic UV light exposure. 2. The accumulation of p53 was also frequently detected in the epidermis adjacent to basal cell carcinoma developing on the face that was usually sun-exposed. In the epidermis adjacent to basal cell carcinoma, unlike normal epidermis with usual sun exposure that was scattered pattern, the stained cells were occasionally clustered in small areas of the epidermis. 3. A missense mutation was not found in the epidermis adjacent to basal cell carcinoma. 4. The correlation between immunohistochemicl overexpression or pattern and underlying mutation is not absolute, but there might be useful as excisional marker because the p53 staining positive cells ,that was clustered pattern, were possible result for clonal expansion of p53 mutant cells.

Circuit Weight Training이 體造率, 筋力, 筋持久力 및 心肺機能에 미치는 影響

金光中,金海中 瑞逸專門大學 1992 論文集 Vol.10 No.-

The purpose of this study is to investigate the effect of circuit weight training on body composition, Muscle stregth, Muscular endurance and cardiopulmonary function The subjects were ten male college students Who exercised circuit weight training 3 times per week. The results were as follows ①Body composition were not significantly changed after training ②Muscle strength and Muscular endurance were significantly changed after training (p < 0.05) ③VO_(2)max, VEmax and all out time were significantly increased after ten weeks (p < 0.05)

韓末 愛國啓蒙運動期의 實業敎育 奬勵方案 : 新聞論說을 中心으로

金光重 又石大學校 人文科學硏究所 1997 人文論叢 Vol.4 No.-

외력진동수가 리츠해석법에 미치는 영향

예광일,박중석,노필성,김재웅 동아대학교 건설기술연구소 1998 硏究報告 Vol.22 No.1

The fact that with appropriate selection of the Ritz shapes, only a few of them can be used to represent adequately the response of the original system can be utilized very effectively in the forced response analysis of multi-degree-of-freedom systems. Obviously, a desirable set of Ritz vectors will be one that can adequately represent the spatial distribution of load by the superposition of a minimum number of shapes. It has been demonstrated that dynamic analysis based on Ritz vectors, which are generated by taking into account the spatial distribution of the load yield results which are more accurate than the use of the same number of exact mode shapes. However, because the dynamic response is influenced strongly by the exciting frequency, the exciting frequency in the use of Ritz analysis method is of considerable importance. In this paper, the influence of exciting frequency on Ritz analysis method is compared with mode superposition method with respect to displacement errors and base shear errors.

복강경하 대장절제술을 시행 받는 환자에서 라모세트론과 온단세트론외 술 후 오심 및 구토 예방 효과 비교

김효중;어전영;어근무;어정한;엄세훈;조광래;김명훈 인제대학교 2011 仁濟醫學 Vol.32 No.-

Objectives : We evaluated the efficacy of ramosetron and ondansetron for preventing postoperative nausea and vomiting (PONV) in laparoscopic colectomy. Methods and Materials : Eighty patients who received laparoscopic colectomy were randomly divided into two groups: R group (ramosetron 0.1mg PO) and O group (ondansetron 4mg twice IV). Injection or oral medication was administered before the induction of anesthesia in each group. Injection was administered at the end of surgery in O group. General anesthesia was induced using propofol and rocuronium, and maintained with sevoflurane, remifentanil and air (FiO2 0.5), We investigated the incidences of PONV in each group by the Rhodes index of nausea, vomiting and retching (RINVR) at postoperative 6 and 24 hours. Results : The incidence of PONV was not different between group at each time points after surgery (at postoperative 6 hours: 20% in group R, 17.5% in group 0, at postoperative 24 hours; 12.5% in group R, 7.5% in group 0). There was no difference in the severity of PONV, satisfaction, rescue drug usage. Conclusion : Prophylactic therapy with ramosetron is as effective as conventional prophylactic therapy with ondansetron for preventing PONV in general anesthesia for laparoscopic colectomy.

勿劑 安義에 대한 考察

金光重 又石大學校 1988 論文集 Vol.10 No.-

중력에 의한 경상분지 남부의 지각구조에 대한 연구

최광선,이준동,김광호,허남철 부산대학교 기초과학연구소 1988 부산대학교 기초과학연구소 연구논문집 Vol.8 No.-

The gravity anomaly of the southern part of the Gyeongsang basin and the adjacent sea is analyzed. According to the power spectum analysis method. calculated the mean depth of the moho and the boundary between the sedimentary layer and the basements is 32km and 6km respectively. With these values, regional and residual anomalies of the gravity for each depth are calculated by the running average method and interpreted. By the sin X/X method, the crustal thickness and the depth of the boundary of the sedimentary layer in the southern part of the Gyeongsang basin turns out to vary from 34km to 28km and from 8.5km to 0.5km repectively.

갑상설관 낭종에서 발생한 유두상암 1례

고중화,박기현,이원석,박광화 아주대학교 의과학연구소 1996 아주의학 Vol.1 No.1

Thyroglossal duct cyst is the most common developmental anomaly of the thyroid and the second most common pathology among childhood cervical masses. They present non-tender palpable mass on midline neck, and they are usually asymptomatic. The cysts are usually benign, but one percent of cases is associated with malignancy. From the world literature, 115 cases of malignant thyroglossal duct cyst are available for review. Despite aspiration cytology and the radiologic images, malignant thyroglossal duct cysts are usually comfirmed after surgery. The authors experienced a case of papillary carcinoma arising from the thryroglossal duct cyst without evidence of local invasion.