Hiccup Due to Aripiprazole Plus Methylphenidate Treatment in an Adolescent with Attention Deficit and Hyperactivity Disorder and Conduct Disorder: A Case Report

Meryem Ozlem Kutuk,Gulen Guler,Ali Evren Tufan,Ozgur Kutuk 대한정신약물학회 2017 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.15 No.4

Our case had hiccups arising in an adolescent with the attention deficit and hyperactivity disorder (ADHD) and conduct disorder (CD) after adding aripiprazole treatment to extended-release methylphenidate. Actually, antipsychotics are also used in the treatment of hiccups, but studies suggest that they can cause hiccups as well. Within 12 hours of taking 2.5 mg aripiprazole added to extended-release methylphenidate at a dose of 54 mg/day, 16-year-old boy began having hiccups in the morning, which lasted after 3-4 hours. As a result, aripiprazole was discontinued and methylphenidate was continued alone because we could not convince the patient to use another additional drug due to this side effect. Subsequently, when his behavior got worsened day by day, his mother administered aripiprazole alone again at the dose of 2.5 mg/day at the weekend and continued treatment because hiccup did not occur again. But when it was administered with methylphenidate on Monday, hiccup started again next morning and lasted one hour at this time. In conclusion, we concluded that concurrent use of methylphenidate and aripiprazole in this adolescent led to hiccups.

Influence of modeling agents on the surface properties of an esthetic nano-hybrid composite

Kutuk, Zeynep Bilge,Erden, Ecem,Aksahin, Damla Lara,Durak, Zeynep Elif,Dulda, Alp Can The Korean Academy of Conservative Dentistry 2020 Restorative Dentistry & Endodontics Vol.45 No.1

Objective: The aim of this study was to evaluate the influence of different modeling agents on the surface microhardness (Vickers hardness number; VHN), roughness (Ra), and color change (ΔE) of a nano-hybrid composite with or without exposure to discoloration by coffee. Materials and Methods: Sixty-four cylinder-shaped nano-hybrid composite specimens were prepared using a Teflon mold. The specimens' surfaces were prepared according to the following groups: group 1, no modeling agent; group 2, Modeling Liquid; group 3, a universal adhesive (G-Premio Bond); and group 4, the first step of a 2-step self-adhesive system (OptiBond XTR). Specimens were randomly allocated into 2 groups (n = 8) according to the storage medium (distilled water or coffee). VHN, Ra, and ΔE were measured at 24 hours, 1 week, and 6 weeks. The Kruskal-Wallis test followed by the Bonferroni correction for pairwise comparisons was used for statistical analysis (α = 0.05). Results: Storage time did not influence the VHN of the nano-hybrid composite in any group (p > 0.05). OptiBond XTR Primer application affected the VHN negatively in all investigated storage medium and time conditions (p < 0.05). Modeling Liquid application yielded improved Ra values for the specimens stored in coffee at each time point (p < 0.05). Modeling Liquid application was associated with the lowest ΔE values in all investigated storage medium and time conditions (p < 0.05). Conclusion: Different types of modeling agents could affect the surface properties and discoloration of nano-hybrid composites.

Optimum bracing design under wind load by using topology optimization

Kutuk, M. Akif,Gov, Ibrahim Techno-Press 2014 Wind and Structures, An International Journal (WAS Vol.18 No.5

Seismic and wind load performances of buildings are commonly improved by using bracing systems. In practice, standard bracing systems, such as X, Y, V, and K types are used. To determine the appropriate bracing type, the designer uses trial & error method among the standard bracings to obtain better results. However, using topology optimization yields more efficient bracing systems or new bracing can be developed depending on building and loading types. Determination of optimum bracing type for minimum deformation on a building under the effect of wind load is given in this study. A new bracing system is developed by using topology optimization. Element removal method is used to determine and remove the comparatively inefficient materials. Optimized bracing is compared with proposed bracing types available in the related literature. Maximum deformation value of building is used as performance indicator to compare effectiveness of different bracings to resist wind loads. The proposed bracing, yielded 99%, deformation reduction compared to the unbraced building.

Influence of modeling agents on the surface properties of an esthetic nano-hybrid composite

Kutuk Zeynep Bilge,Erden Ecem,Aksahin Damla Lara,Durak Zeynep Elif,Dulda Alp Can 대한치과보존학회 2020 Restorative Dentistry & Endodontics Vol.45 No.2

Objective: The aim of this study was to evaluate the influence of different modeling agents on the surface microhardness (Vickers hardness number; VHN), roughness (Ra), and color change (ΔE) of a nano-hybrid composite with or without exposure to discoloration by coffee. Materials and Methods: Sixty-four cylinder-shaped nano-hybrid composite specimens were prepared using a Teflon mold. The specimens' surfaces were prepared according to the following groups: group 1, no modeling agent; group 2, Modeling Liquid; group 3, a universal adhesive (G-Premio Bond); and group 4, the first step of a 2-step self-adhesive system (OptiBond XTR). Specimens were randomly allocated into 2 groups (n = 8) according to the storage medium (distilled water or coffee). VHN, Ra, and ΔE were measured at 24 hours, 1 week, and 6 weeks. The Kruskal-Wallis test followed by the Bonferroni correction for pairwise comparisons was used for statistical analysis (α = 0.05). Results: Storage time did not influence the VHN of the nano-hybrid composite in any group (p > 0.05). OptiBond XTR Primer application affected the VHN negatively in all investigated storage medium and time conditions (p < 0.05). Modeling Liquid application yielded improved Ra values for the specimens stored in coffee at each time point (p < 0.05). Modeling Liquid application was associated with the lowest ΔE values in all investigated storage medium and time conditions (p < 0.05). Conclusion: Different types of modeling agents could affect the surface properties and discoloration of nano-hybrid composites.

Performance of the predator Amblyseius swirskii (Acari: Phytoseiidae) on greenhouse eggplants in the absence and presence of pine Pinus brutia (Pinales:Pinaceae) pollen

Halil Kutuk 한국곤충학회 2017 Entomological Research Vol.47 No.4

In Turkey, the western thrips Frankliniella occidentalis (Pergande) is a key pest affecting eggplants grown in greenhouses for which an appropriate control strategy is under investigation. It was observed in a previous study that the release of the beneficial predatory mite Amblyseius swirskii (Athias‐Henriot) alone did not result in an effective control of thrips on eggplants. Since pollen is known to improve control efficiency of predators, this study was undertaken to investigate if provision of pollen to eggplants can greatly improve the efficiency of A. swirskii in controlling thrips. The experiments were carried out in both greenhouse and low tunnel. The provision of pollen led to a significant increase in the predator population density on the eggplants but did not result in an effective control of the thrips populations. In this paper, various factors are discussed that could have affected the efficiency of the predatory mite in controlling F. occidentalis on eggplants.

Optimum bracing design under wind load by using topology optimization

M. Akif Kutuk,Ibrahim Gov 한국풍공학회 2014 Wind and Structures, An International Journal (WAS Vol.18 No.5

Seismic and wind load performances of buildings are commonly improved by using bracing systems. In practice, standard bracing systems, such as X, Y, V, and K types are used. To determine the appropriate bracing type, the designer uses trial & error method among the standard bracings to obtain better results. However, using topology optimization yields more efficient bracing systems or new bracing can be developed depending on building and loading types. Determination of optimum bracing type for minimum deformation on a building under the effect of wind load is given in this study. A new bracing system is developed by using topology optimization. Element removal method is used to determine and remove the comparatively inefficient materials. Optimized bracing is compared with proposed bracing types available in the related literature. Maximum deformation value of building is used as performance indicator to compare effectiveness of different bracings to resist wind loads. The proposed bracing, yielded 99%, deformation reduction compared to the unbraced building.

Korea and Turkey Free Trade Agreement : A Qualitative and Quantitative Assessment

Zubeyir KILINC,Merve Mavus KUTUK,Arif ODUNCU 한국무역학회 2015 Journal of Korea trade Vol.19 No.2

The trade volume and diversity of the products traded between Korea and Turkey has been increasing since the early 2000s. On top of this, the enthusiasm of the countries in exploring new opportunities led them to start negotiations on signing a free trade agreement in 2010. The process was finalized in 2012. The agreement requires that all trade tariffs on industrial products and most of the tariffs on agricultural products will be removed in seven and ten years, respectively. To the best of our knowledge, this study is the first one that investigates possible economic impacts of this agreement on the Korean and Turkish economies. It employs a computable general equilibrium model and uses the Global Trade Analysis Project database. It finds that the agreement will benefit both parties in terms of GDP and exports. In particular, total gains of Korea and Turkey will be as high as 0.129 and 0.054 percent of their respective GDPs. Finally, the exports of Korea might increase up to 0.139 percent whereas that of Turkey might increase by 0.164 percent.

Amenorrhea as a Side Effect of Low Dose Aripiprazole: An Adolescent Case

Gulen Guler,Meryem Ozlem Kutuk,Halil Kara 대한정신약물학회 2018 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.16 No.3

Amenorrhea, oligomenorrhea, galactorrhoea, gynecomastia, infertility, and sexual dysfunction may arise as a consequence of hyperprolactinemia. Hyperprolactinemia is one of major side effects of treatment with antipsychotics, but aripiprazole is known as a dopamine stabilizer antipsychotic which can be used to improve hyperprolactinemia. In this report, it was described that an adolescent patient experienced amenorrhea after adding very low dose aripiprazole to ongoing fluoxetine treatment regime for major depressive disorder. Additionally, this case showed that the patient recovered from the amenorrhea with replacement of aripiprazole with quetiapine.

Foreign Direct Investment; Firm heterogeneity; Free Trade Agreement

Zubeyir KILINC,Merve Mavus KUTUK,Arif ODUNCU 한국무역학회 2015 Journal of Korea trade Vol.19 No.2

The trade volume and diversity of the products traded between Korea and Turkey

Effect of various bleaching treatments on shear bond strength of different universal adhesives and application modes

Oz, Fatma Dilsad,Kutuk, Zeynep Bilge The Korean Academy of Conservative Dentistry 2018 Restorative Dentistry & Endodontics Vol.43 No.2

Objectives: The aim of this in vitro study was to evaluate the bond strength of 2 universal adhesives used in different application modes to bleached enamel. Materials and Methods: Extracted 160 sound human incisors were used for the study. Teeth were divided into 4 treatment groups: No treatment, 35% hydrogen peroxide, 16% carbamid peroxide, 7.5% carbamid peroxide. After bleaching treatments, groups were divided into subgroups according to the adhesive systems used and application modes (n = 10): 1) Single Bond Universal, etch and rinse mode; 2) Single Bond Universal, self-etch mode; 3) Gluma Universal, etch and rinse mode; 4) Gluma Universal, self-etch mode. After adhesive procedures nanohybrid composite resin cylinders were bonded to the enamel surfaces. All specimens were subjected to shear bond strength (SBS) test after thermocycling. Data were analyzed using a 3-way analysis of variance (ANOVA) and Tukey post hoc test. Results: No significant difference were found among bleaching groups (35% hydrogen peroxide, 16% carbamid peroxide, 7.5% carbamid peroxide, and no treatment groups) in the mean SBS values. There was also no difference in SBS values between Single Bond Universal and Gluma Universal at same application modes, whereas self-etch mode showed significantly lower SBS values than etch and rinse mode (p < 0.05). Conclusions: The bonding performance of the universal adhesives was enhanced with the etch and rinse mode application to bleached enamel and non-bleached enamel.