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Kuo-Ching Tseng,Chun-Tse Chen,Chun-An Cheng 전력전자학회 2016 JOURNAL OF POWER ELECTRONICS Vol.16 No.2
This paper proposes a novel high-efficiency high-step-up interleaved converter with a voltage multiplier, which is suitable for electric vehicle power management applications. The proposed interleaved converter is capable of achieving high step-up conversion by employing a voltage-multiplier circuit. The proposed converter lowers the input-current ripple, which can extend the input source"s lifetime, and reduces the voltage stress on the main switches. Hence, large voltage spikes across the main switches are alleviated and the efficiency is improved. Finally, a prototype circuit with an input voltage of 24 V, an output voltage of 380 V, and an output rated power of 1 kW is implemented and tested to demonstrate the functionality of the proposed converter. Moreover, satisfying experimental results are obtained and discussed in this paper. The measured full-load efficiency is 95.2%, and the highest measured efficiency of the proposed converter is 96.3%.
Will Taiwan`s Economy be Marginalized by China? A Macroeconomic Policy Coordination Approach
Kuo Chun Yeh 연세대학교 동서문제연구원 2009 Global economic review Vol.38 No.1
In Taiwan, economic marginalization has become a major concern that has resulted from the fast growing Chinese economy, imbalanced cross-strait economic and political relations, and a failure to participate in important international trade and financial organizations. Is a China-Taiwan policy cooperative mechanism the best choice for Taiwan`s economic welfare? This paper is to measure Taiwan`s economic marginalization by an international policy coordination approach instead of the conventional free trade agreements. We simulate macroeconomic adjustments of Taiwan and its main economic partners (China and the U.S.) according to the different institutional scenarios and economic shocks. The baseline simulation and sensitivity analyses imply that at the current stage policy coordination between China and Taiwan cannot come into effect without the U.S.`s participation.
Current Trends and Recent Advances in Diagnosis, Therapy, and Prevention of Hepatocellular Carcinoma
Wang, Chun-Hsiang,Wey, Keh-Cherng,Mo, Lein-Ray,Chang, Kuo-Kwan,Lin, Ruey-Chang,Kuo, Jen-Juan Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.9
Hepatocellular carcinoma (HCC) has been one of the most fatal malignant tumors worldwide and its associated morbidity and mortality remain of significant concern. Based on in-depth reviews of serological diagnosis of HCC, in addition to AFP, there are other biomarkers: Lens culinaris agglutinin-reactive AFP (AFP-L3), descarboxyprothrombin (DCP), tyrosine kinase with Ig and eprdermal growth factor (EGF) homology domains 2 (TIE2)-espressing monocytes (TEMs), glypican-3 (GPC3), Golgi protein 73 (GP73), interleukin-6 (IL-6), and squamous cell carcinoma antigen (SCCA) have been proposed as biomarkers for the early detection of HCC. The diagnosis of HCC is primarily based on noninvasive standard imaging methods, such as ultrasound (US), dynamic multiphasic multidetector-row CT (MDCT) and magnetic resonance imaging (MRI). Some experts advocate gadolinium diethyl-enetriamine pentaacetic acid (Gd-EOB-DTPA) MRI and contrast-enhanced US as the promising imaging madalities of choice. With regard to recent advancements in tissue markers, many cuting-edge technologies using genome-wide DNA microarrays, qRT-PCR, and proteomic and inmunostaining studies have been implemented in an attempt to identify markers for early diagnosis of HCC. Only less than half of HCC patients at initial diagnosis are at an early stage treatable with curative options: local ablation, surgical resection, or liver transplant. Transarterial chemoembolization (TACE) is considered the standard of care with palliation for intermediate stage HCC. Recent innovative procedures using drug-eluting-beads and radioembolization using Yttrium-90 may exhibit beneficial effects in HCC treatment. During the past few years, several molecular targeted agents have been evaluated in clinical trials in advanced HCC. Sorafenib is currently the only approved systemic treatment for HCC. It has been approved for the therapy of asymptomatic HCC patients with well-preserved liver function who are not candidates for potentially curative treatments, such as surgical resection or liver transplantation. In the USA, Europe and particularly Japan, hepatitis C virus (HCV) related HCC accounts for most liver cancer, as compared with Asia-Pacific regions, where hepatitis B virus (HBV) may play a more important role in HCC development. HBV vaccination, while a vaccine is not yet available against HCV, has been recognized as a best primary prevention method for HBV-related HCC, although in patients already infected with HBV or HCV, secondary prevention with antiviral therapy is still a reasonable strategy. In addition to HBV and HCV, attention should be paid to other relevant HCC risk factors, including nonalcoholic fatty liver disease due to obesity and diabetes, heavy alcohol consumption, and prolonged aflatoxin exposure. Interestingly, coffee and vitamin K2 have been proven to provide protective effects against HCC. Regarding tertiary prevention of HCC recurrence after surgical resection, addition of antiviral treatment has proven to be a rational strategy.
Tseng, Kuo-Ching,Chen, Chun-Tse,Cheng, Chun-An The Korean Institute of Power Electronics 2016 JOURNAL OF POWER ELECTRONICS Vol.16 No.2
This paper proposes a novel high-efficiency high-step-up interleaved converter with a voltage multiplier, which is suitable for electric vehicle power management applications. The proposed interleaved converter is capable of achieving high step-up conversion by employing a voltage-multiplier circuit. The proposed converter lowers the input-current ripple, which can extend the input source's lifetime, and reduces the voltage stress on the main switches. Hence, large voltage spikes across the main switches are alleviated and the efficiency is improved. Finally, a prototype circuit with an input voltage of 24 V, an output voltage of 380 V, and an output rated power of 1 kW is implemented and tested to demonstrate the functionality of the proposed converter. Moreover, satisfying experimental results are obtained and discussed in this paper. The measured full-load efficiency is 95.2%, and the highest measured efficiency of the proposed converter is 96.3%.
Recent Research and A, pp.ication of Earthquake Protection System in Taiwan
Chang Kuo Chun,Tsai Meng Hao 한국지진공학회 1998 한국지진공학회논문집 Vol.2 No.3
Research and a, pp.ication of earthquake protection system in Taiwan have become very active since about ten years ago. Many passive isolators, etc., have been studied extensively. These studies have resulted in a few practical a, pp.ications and proposals of two draft design provisions for seismic isolation design of bridges and buildings. In addition to the pass control, analytical studies on active semi-active control have also been very active and the experimental studies have scheduled in the near future. This paper summarise the progress on recent research and a, pp.ication of earthquake protection systems in Taiwan. The emphases are given to the control systems that have been a, pp.ied in practical a, pp.ications.
Tsai Li-Jen,Chung Chi-Hsiang,Lin Chien-Jung,Su Sheng-Chiang,Kuo Feng-Chih,Liu Jhih-Syuan,Chen Kuan-Chan,Ho Li-Ju,Kuo Chih-Chun,Chang Chun-Yung,Lin Ming-Hsun,Chu Nain-Feng,Lee Chien-Hsing,Hsieh Chang-H 한국한의학연구원 2022 Integrative Medicine Research Vol.11 No.2
Background: Diabetic patients are at high risk of developing cancer. Traditional Chinese medicine (TCM) has become increasingly popular as an adjuvant treatment for patients with chronic diseases, and some studies have identified its beneficial effect in diabetic patients with cancer. The purpoes of this study was to outline the potential of TCM to attenuate hospitalization and mortality rates in diabetic patients with carcinoma in situ (CIS). Methods: A total of 6,987 diabetic subjects with CIS under TCM therapy were selected from the National Health Insurance Research Database of Taiwan, along with 38,800 of 1:1 sex-, age-, and index year-matched controls without TCM therapy. Cox proportional hazard analysis was conducted to compare hospitalization and mortality rates during an average of 15 years of follow-up. Results: A total of 3,999/1,393 enrolled-subjects (28.62%/9.97%) had hospitalization/mortality, including 1,777/661 in the TCM group (25.43%/9.46%) and 2,222/732 in the control group (31.80%/10.48%). Cox proportional hazard regression analysis showed a lower rate of hospitalization and mortality for subjects in the TCM group (adjusted HR=0.536; 95% CI=0.367–0.780, P<0.001; adjusted HR=0.783; 95% CI=0.574– 0.974, P = 0.022). Kaplan-Meier analysis showed that the cumulative risk of hospitalization and mortality in the case and control groups was significantly different (log rank, P<0.001 and P = 0.011, respectively). Conclusions: Diabetic patients with CIS under TCM therapy were associated with lower hospitalization and mortality rates compared to those without TCM therapy. Thus, TCM application may reduce the burden of national medical resources.
Chun-An Cheng,Chien-Hsuan Chang,Hung-Liang Cheng,Tsung-Yuan Chung,Ching-Hsien Tseng,Kuo-Ching Tseng 전력전자학회 2016 JOURNAL OF POWER ELECTRONICS Vol.16 No.4
This study proposes a single-stage light-emitting diode (LED) tube lamp driver with input-current shaping for T8/T10-type fluorescent lamp replacements. The proposed AC–DC LED driver integrates a dual-boost converter with coupled inductors and a half-bridge series-resonant converter with a bridge rectifier into a single-stage power conversion topology. This paper presents the operational principles and design considerations for one T8-type 18 W-rated LED tube lamp with line input voltages ranging from 100 V rms to 120 V rms. Experimental results for the prototype driver show that the highest power factor (PF = 0.988), lowest input current total harmonic distortion (THD = 7.22%), and highest circuit efficiency (η = 92.42%) are obtained at an input voltage of 120 V. Hence, the proposed driver is feasible for use in energy-efficient indoor lighting applications.
Using Kano Model to Explore the Charm of Painting Art Works in the Meaning of Life and Death
Kuo, Chin-Chin,Chen, Chun-Chih,Chia-Hui Huang 한국일러스트레이션학회 2022 일러스트레이션 포럼 Vol.23 No.70
The study of life and death is a learning topic. When we face to the life and death issue, it relates to our own lives. Most people are happy with life, but are full of fear of death. This research uses life and death as an example to explore "the creation of the meaning of life and death in composite media." It is hoped that through the extension of the meaning and images of life and death, the themes and elements of painting creation can be integrated to provide the exploration and thinking direction of the meaning of life. This research hopes to extend the meaning and imagery of life and death and incorporate the creative themes and elements of mixed media, so as to provide a direction for the exploration and thinking of the meaning of life. Applying the Miryoku Engineering Evaluation Grid Method to clarify the relationship between the meaning of life and death, style and perceptual imagery, and through the artistic creation of mixed media, summarize the preferences of mixed media creation works that affect the expression of birth and death images. Using the Evaluation Grid Method, 7 people with high involvement in the creation of mixed media and the imagery of life and death were conducted in-depth interviews on the charm and feelings of the meaning of life and death. By summarizing the attractiveness factors of choosing between life and death, the conclusion can be used as a basis for the development of future painting creation after subsequent verification and research on the purpose of life, the meaning of life, the value of survival, and the true meaning of death.