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RISS 인기검색어
- 검색키워드
- 저자 : Koyuncuoglu (검색결과 2 건)
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MODELING AND VALIDATION OF TURBOCHARGED DIESEL ENGINE AIRPATH AND COMBUSTION SYSTEMS
B. UNVER,Y. KOYUNCUOGLU,M. GOKASAN,S. BOGOSYAN 한국자동차공학회 2016 International journal of automotive technology Vol.17 No.1
The ultimate aim of this study is the development of an engine modeling approach that would facilitate the design of model-based control techniques for diesel engines. This will allow for the development of more generalized, modular control strategies for different engine types and sizes as opposed to the commonly practiced map-based engine control strategies that depend on maps and feedforward control and require lengthy modifications every time a change is made. Also, most engine modeling studies focus on either airpath or combustion systems, treating these models and their validation individually, and not as an integrated system as is actually the case. To address the need for more realistic models suitable for model-based control design, this study develops a combined airpath and combustion model for the engine, using analytical models wherever possible and derives a model with appropriate control inputs and outputs that could be used in a control scheme. The inclusion of the actuator dynamics of the Exhaust gas recirculation (EGR), variable geometry turbine (VGT), and Throttle (THR) valves in the airpath model and the consideration of nonlinearities in the combustion model allow for the development of a more thorough engine model, as well as the validation of subsystems and the whole integrated engine model using a complete World Harmonized Transient Cycle (WHTC). This test cycle finds limited use due to its challenging transients, and yet, is the demanded test cycle for emission regulations nowadays. These are unique aspects of this modeling study, the results of which indicate that the developed engine model could be used in control design and hardware-in-the-loop simulation (HILS) based engine control prototyping.
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Evren Yilmaz,Meral Koyuncuoglu,İlknur Bilkay Görken,Emre Okyay,Bahadir Saatli,Emine Cagnur Ulukus,Ugur Saygili 대한부인종양학회 2011 Journal of Gynecologic Oncology Vol.22 No.2
Objective: To determine matrix metalloproteinase-2 and survivin expressions in endometrial cancers, their relation to clinical and histologic parameters and to investigate any difference in the expression of these markers between endometrioid and nonendometrioid cancers. Methods: Ninety-five patients with endometrial cancer, were included. Matrix metalloproteinase-2 and survivin expressions were analyzed immunohistochemically from paraffin-embedded tissues by using specific monoclonal antibodies. Results: Survivin nuclear expression was higher in endometrioid cancer as compared to nonendometrioid cancer (p=0.040), but there was no difference for cytoplasmic survivin and matrix metalloproteinase-2 expressions between type I and type II carcinomas. Survivin cytoplasmic staining was significantly lower in patients with deep myometrial invasion (p=0.038). Nuclear expression of survivin is decreased in histologic grade 3 tumors compared to grade 1 and 2 tumors (p=0.013), but there is no difference between grade 1 and 2. We did not find any statistically significant difference between survivin or matrix metalloproteinase-2 expressions and survival. Conclusion: Survivin and matrix metalloproteinase-2 are present in endometrioid and nonendometrioid cancers. Grade 1 and 2 tumors and carcinomas having myometrial invasion less than 50% have higher survivin expression. These results supports that, survivin may play an important role in early stage tumors and early phases of tumor development. We did not find any association between matrix metalloproteinase-2 expression and classical prognostic factors in endometrial cancer and both proteins were not associated with survival. Objective: To determine matrix metalloproteinase-2 and survivin expressions in endometrial cancers, their relation to clinical and histologic parameters and to investigate any difference in the expression of these markers between endometrioid and nonendometrioid cancers. Methods: Ninety-five patients with endometrial cancer, were included. Matrix metalloproteinase-2 and survivin expressions were analyzed immunohistochemically from paraffin-embedded tissues by using specific monoclonal antibodies. Results: Survivin nuclear expression was higher in endometrioid cancer as compared to nonendometrioid cancer (p=0.040), but there was no difference for cytoplasmic survivin and matrix metalloproteinase-2 expressions between type I and type II carcinomas. Survivin cytoplasmic staining was significantly lower in patients with deep myometrial invasion (p=0.038). Nuclear expression of survivin is decreased in histologic grade 3 tumors compared to grade 1 and 2 tumors (p=0.013), but there is no difference between grade 1 and 2. We did not find any statistically significant difference between survivin or matrix metalloproteinase-2 expressions and survival. Conclusion: Survivin and matrix metalloproteinase-2 are present in endometrioid and nonendometrioid cancers. Grade 1 and 2 tumors and carcinomas having myometrial invasion less than 50% have higher survivin expression. These results supports that, survivin may play an important role in early stage tumors and early phases of tumor development. We did not find any association between matrix metalloproteinase-2 expression and classical prognostic factors in endometrial cancer and both proteins were not associated with survival.
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