Serum level changes of long chain-polyunsaturated fatty acids in patients undergoing periodontal therapy combined with one year of omega-3 supplementation: a pilot randomized clinical trial

Martinez, Gisele Lago,Koury, Josely Correa,Martins, Marcela Anjos,Nogueira, Fernanda,Fischer, Ricardo Guimaraes,Gustafsson, Anders,Figueredo, Carlos Marcelo S. Korean Academy of Periodontology 2014 Journal of Periodontal & Implant Science Vol.44 No.4

Purpose: We aimed to investigate the impact of nonsurgical periodontal treatment combined with one-year dietary supplementation with omega (${\omega}$)-3 on the serum levels of eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), docosapentaenoic acid (DPA), and arachidonic acid (AA). Methods: Fifteen patients with chronic generalized periodontitis were treated with scaling and root planing. The test group consisted of seven patients ($43.1{\pm}6.0$ years) supplemented with ${\omega}$-3, consisting of EPA plus DHA, three capsules, each of 300 mg of ${\omega}$-3 (180-mg EPA/120-mg DHA), for 12 months. The control group was composed of eight patients ($46.1{\pm}11.6$ years) that took a placebo capsule for 12 months. The periodontal examination and the serum levels of DPA, EPA, DHA, and AA were performed at baseline (T0), and 4 (T1), and 12 (T2) months after therapy. Results: In the test group, AA and DPA levels had been reduced significantly at T1 (P<0.05). AA and EPA levels had been increased significantly at T2 (P<0.05). The ${\Delta}EPA$ was significantly higher in the test compared to the placebo group at T2-T0 (P=0.02). The AA/EPA had decreased significantly at T1 and T2 relative to baseline (P<0.05). Conclusions: Nonsurgical periodontal treatment combined with ${\omega}$-3 supplementation significantly increased the EPA levels and decreased the AA/EPA ratio in serum after one year follow-up. However, no effect on the clinical outcome of periodontal therapy was observed.

Serum level changes of long chain-polyunsaturated fatty acids in patients undergoing periodontal therapy combined with one year of omega-3 supplementation: a pilot randomized clinical trial

Gisele Lago Martinez,Josely Correa Koury,Marcela Anjos Martins,Fernanda Nogueira,Ricardo Guimarães Fischer,Anders Gustafsson,Carlos Marcelo S Figueredo 대한치주과학회 2014 Journal of Periodontal & Implant Science Vol.44 No.4

Purpose: We aimed to investigate the impact of nonsurgical periodontal treatment combined with one-year dietary supplementation with omega (ω)-3 on the serum levels of eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), docosapentaenoic acid (DPA), and arachidonic acid (AA). Methods: Fifteen patients with chronic generalized periodontitis were treated with scaling and root planing. The test group consisted of seven patients (43.1±6.0 years) supplemented with ω-3, consisting of EPA plus DHA, three capsules, each of 300 mg of ω-3 (180-mg EPA/120-mg DHA), for 12 months. The control group was composed of eight patients (46.1±11.6 years) that took a placebo capsule for 12 months. The periodontal examination and the serum levels of DPA, EPA, DHA, and AA were performed at baseline (T0), and 4 (T1), and 12 (T2) months after therapy. Results: In the test group, AA and DPA levels had been reduced significantly at T1 (P<0.05). AA and EPA levels had been increased significantly at T2 (P<0.05). The ΔEPA was significantly higher in the test compared to the placebo group at T2–T0 (P=0.02). The AA/EPA had decreased significantly at T1 and T2 relative to baseline (P<0.05). Conclusions: Nonsurgical periodontal treatment combined with ω-3 supplementation significantly increased the EPA levels and decreased the AA/EPA ratio in serum after one year follow-up. However, no effect on the clinical outcome of periodontal therapy was observed.

Distributed and Nonsteady-State Model of an Air Cooler Working with R22 and R410A

R. O. Nunes,L. F. N. Castro,L. Machado,R. N. N. Koury 대한설비공학회 2016 International Journal of Air-Conditioning and Refr Vol.24 No.2

The restrictions imposed by Montreal Protocol for use of CFCs fluids and Kyoto Protocol to HCFCs have motivated researchers and the industry to seek new alternatives. Within this context, R410A has emerged as one of the most likely replacement of R22. The purpose of this work is to develop a numerical model of an air cooler to simulate its behavior operating under dynamic conditions loaded with R22 or R410A refrigerant. The model divides the air cooler in volumes control in which mass, energy, and momentum balance equations are applied and solved. Theoretical data obtained by model simulations repeated tendencies observed in experimental data taken from literature. Model simulations have also shown that for a step change in the inlet refrigerant mass flow, the superheating response of air cooler is almost the same when it is working with R22 or R410A refrigerant.

USING A HEAT PUMP AS AN ALTERNATIVE TO SUPPORT SOLAR COLLECTOR FOR WATER HEATING IN BRAZIL

ROBERTS VINICIUS DE MELO REIS,RAPHAEL NUNES OLIVEIRA,LUIZ MACHADO,RICARDO NICOLAU NASSAR KOURY 대한설비공학회 2012 International Journal Of Air-Conditioning and Refr Vol.20 No.3

With related greenhouse e®ect environmental issues linked to the constant problems of the °uctuations in oil prices, the use of solar energy is an important renewable energy source. Brazil is a country which is privileged considering the high rates of solar irradiation present throughout almost the entire national territory. Nevertheless, during certain times of the year, there is a solar energy de¯cit, which leads solar systems to require electrical resistance support at these times. The use of electrical resistance represents 23.5% of electric energy consumption and it presents a low residential energy e±ciency. The purpose of this work is an alternative technical design for reduction of electric energy consumption through the use of a solar energy system together with a generating heat pump for water heaters for households, as well as the ¯nancial feasibility study on the use of this system. One such heat pump has been designed, constructed and tested experimentally. The average performance coe±cient is equal to 2.10, a low value due to the use of a hermetic reciprocating compressor. Despite this low moderate price coe±cient of acquisition and installation of a heat pump, one can allow a return on investment in from 2.1 to 3.3 years, whereas the equipment has a useful life of about 20 years, this period of return on investment is interesting.

Adiabatic Capillary Tube Model for a Carbon Dioxide Transcritical Cycle

R. O. Nunes,R. N. Faria,N. Bouzidi,L. Machado,R. N. N. Koury 대한설비공학회 2015 International Journal Of Air-Conditioning and Refr Vol.23 No.2

This paper presents a mathematical model for a capillary tube using CO2 as fluid in steady flow transcritical cycle. The capillary tube is divided into N volumes controls and the model is based on applying the equations of conservation of energy, mass and momentum in the fluid in each of these volumes controls. The model calculates the mass flow of the CO2 in the capillary tube as a function of CO2 pressures at the inlet and outlet of the capillary and the temperature of CO2 at the input of this device. The capillary tube is considered to be adiabatic, and the limit of operation due to blocked flow condition is also considered in the model. The validation of the model was performed with experimental data and the results showed that the model is capable of predicting the mass flow in the capillary tube with errors less than 10%. The model was also used to determine the minimum diameter of the capillary tube for various conditions of CO2 transcritical cycle.

Digestive Neuroendocrine Tumor Distribution and Characteristics According to the 2010 WHO Classification: a Single Institution Experience in Lebanon

Kourie, Hampig Raphael,Ghorra, Claude,Rassy, Marc,Kesserouani, Carole,Kattan, Joseph Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.5

Background: Gastro-entero-pancreatic neuroendocrine neoplasms (GEP-NEN) are relatively rare tumors, not equally distributed in gastro-intestinal system. In 2010, a revised version of the WHO classification of GEP-NENs was published. This study reports for the first time the distribution and characteristics of GEP-NEN in a Lebanese population. Materials and Methods: This descriptive retrospective study concerns all the digestive neuroendocrine tumors with their characteristics diagnosed in $H\hat{o}tel$ Dieu de France in Beirut, Lebanon from 2001 to 2012, all the pathology reports being reanalyzed according to the latest WHO 2010 classification. The characteristics and features of GEP-NEN analyzed in this study were age, gender, grade and site. Results: A total of 89 GEP-NENs were diagnosed, representing 28.2% of all neuroendocrine tumors. The mean age of GEP-NEN patients was 58.7 years and the M/F sex ratio was 1.2. The primary localization was as follows: 21.3%(19) pancreatic, 18% (16) gastric, 15.7% (14) duodenal, 11.2% (10) appendix, 10.1% (9) intestinal, 10.1% (9) colorectal (7.9% colonic and 2.2% rectal), 5.6% (4) hepatic, 2.2% (2) ampulla, 1.1% (1) esophageal and 7.9%(5) NOS digestive (metastatic with unknown primary). Of the 89 patients with GEP-NEN, 56.2% (50) were diagnosed as grade I, 11.2% (10) as grade II, 20.2% (18) as grade III and 12.4% (11) were considered as mixed adeno-neuroendocrine carcinomas (MANEC). Conclusions: This study, one of the rare examples based on the 2010 WHO classification of neuroendocrine tumors in the literature, indicates that in the Lebanese population, all duodenal and appendicular tumors are G1 and the majority of MANEC tumors are gastric and pancreatic tumors. Moreover, more duodenal tumors and fewer rectal tumors were encountered in our study compared to European reports.

EMISSION TOMOGRAPHY : A CONCISE THEORETICAL OVERVIEW

Kouris, Kypros 대한핵의학회 1984 핵의학 분자영상 Vol.18 No.1

Outcome of Breast Cancer Screening: A Lebanese Single Institution Experience

Kourie, Hampig Raphael,Daher, Alain,Matar, Dany,Antoun, Joelle,Salloum, Lony,Kattan, Joseph Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.21

Background: Since 2002, from October till December of each year, the Lebanese Ministry of Public Health conducts a mammogram based breast cancer screening campaign in the whole country for women over 40 years of age. These mammograms are performed free of charge in governmental hospitals or for reduced fees in private hospitals. The aim of this study is to analyze the direct impact of this campaign on cancer detection and subsequent treatment. Materials and Methods: Radiologic records of women screened with a mammogram during the campaign period from October till December 2012 at Saint Joseph Hospital, Baouchrieh, Beirut, were reviewed. Results of mammograms were reported using the ACR score. Women with ACR score ${\geq}4$ were tracked and investigated. Results: 900 screening mammograms were performed; median age was 55.2 years (range:31-81 years). Some 826 (91.8%) had an ACR score of ${\leq}2$; 66 (7.3%) an ACR =3 and only 8 (0.89%) an ACR=4. Thus, less than 1% (8/900) of all screened women were considered at high risk and needed a close follow-up. Among these 8 women, 4 underwent surgery for an early breast cancer, one had synchronous metastatic breast cancer and two were lost to follow-up. Conclusions: To coclude, Among 900-screened women for BC, less than 1 % (8 out of 900) were at high risk of hiding a BC (ACR=4), half of them benefited from early therapy (4 women out of 900) and one was a false positive. Larger studies on national level should be accomplished to have a complete data on breast cancer screening in Lebanon. The results of these studies can affect the Lebanese health policy regarding BC.

Histologic Distribution of Pulmonary Tumors in Lebanon: A 5-Year Single Institution Experience

Kourie, Hampig Raphael,Rassy, Marc,Ghorra, Claude,Naderi, Samah,Kattan, Joseph Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.14

Background: To compare the current histologic distribution of lung cancer in Lebanon to the worldwide trends, according to the 2004 WHO Classification. Materials and Methods: 1,760 patients with a pulmonary pathology examination at Hotel-Dieu de France University Hospital between July 2009 and July 2014 were included. Results: Some 676 out of the total investigated patients (38.4%) had a lung tumor. In 665 (98.4%) the tumors were malignant, with a mean age at diagnosis of 63.8 years and a male/female (M/F) sex ratio of 1.7:1. Among the malignant tumors, 86.2% were epithelial tumors with a mean age at diagnosis of 64.8 years and an M/F sex ratio of 1.9. Other malignant tumors consisted of metastatic tumors (10.2%), lymphoproliferative tumors (2.1%) and mesenchymal tumors (1.5%). Most common carcinoma subtypes were adenocarcinoma (48.0%), squamous cell carcinoma (23.0%) and small cell carcinoma (13.3%). Carcinoid tumors were the only carcinoma subtype with an M/F sex ratio below 1 (0.7). Salivary gland tumors were the carcinoma with lowest mean age at diagnosis (45.5 years). Conclusions: The histologic distribution of lung tumors in Lebanon is similar to that in developed countries. We believe this resemblance is due to common smoking habits, known to be responsible for the increase of lung adenocarcinoma at the expense of other subtypes.

Quality Control Systems, for railway passenger transport. Case study: Hellenic Railways

Panagiota Kouri-Toyas 한국철도학회 2008 한국철도학회 학술발표대회논문집 Vol.- No.-