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      • KCI등재

        Intermodal Inland Waterway Transport: Modelling Conditions Influencing Its Cost Competitiveness

        Bart WIEGMANS,Rob KONINGS 한국해운물류학회 2015 The Asian journal of shipping and Logistics Vol.31 No.2

        In this paper a model is developed to analyse and compare the transport costs of intermodal inland waterway transport and road-only-transport. The influence of the economies of scale in inland waterway transport and terminal operations are taken into account in the analysis. In the model the transport costs are defined and related to different transport operations and conditions (e.g. share of empty kilometres, capacity usage of terminals, etc.) in order to analyse the sensitivity of the cost performance of intermodal inland waterway transport. By doing this it is possible to analyse to what extent intermodal freight transport is competitive with road-only transport in terms of transport costs and specific operations and conditions (both in shipping and terminal). The conclusions prove that roundtrips, drop & pick operations in pre- and end-haulage and smaller containers (20ft instead of 40ft) considerably improve the competitiveness of intermodal inland waterway transport, while the relative high cost operations in small terminals reduce the competitiveness of intermodal inland waterway transport.

      • SCISCIESCOPUS

        Global-scale assessment and combination of SMAP with ASCAT (active) and AMSR2 (passive) soil moisture products

        Kim, Hyunglok,Parinussa, Robert,Konings, Alexandra G.,Wagner, Wolfgang,Cosh, Michael H.,Lakshmi, Venkat,Zohaib, Muhammad,Choi, Minha Elsevier 2018 Remote sensing of environment Vol.204 No.-

        <P><B>Abstract</B></P> <P>Global-scale surface soil moisture (SSM) products retrieved from active and passive microwave remote sensing provide an effective method for monitoring near-real-time SSM content with nearly daily temporal resolution. In the present study, we first inter-compared global-scale error patterns and combined the Soil Moisture Active Passive (SMAP), Advanced Scatterometer (ASCAT), and Advanced Microwave Scanning Radiometer 2 (AMSR2) SSM products using a triple collocation (TC) analysis and the maximized Pearson correlation coefficient (R) method from April 2015 to December 2016. The Global Land Data Assimilation System (GLDAS) and global <I>in situ</I> observations were utilized to investigate and to compare the quality of satellite-based SSM products.</P> <P>The average R-values of SMAP, ASCAT, and AMSR2 were 0.74, 0.64, and 0.65 when they compared with <I>in situ</I> networks, respectively. The ubRMSD values were (0.0411, 0.0625, and 0.0708) m<SUP>3</SUP> m<SUP>−3</SUP>; and the bias values were (−0.0460, 0.0010, and 0.0418) m<SUP>3</SUP> m<SUP>−3</SUP> for SMAP, ASCAT, and AMSR2, respectively. The highest average R-values from SMAP against the <I>in situ</I> results are very encouraging; only SMAP showed higher R-values than GLDAS in several <I>in situ</I> networks with low ubRMSD (0.0438m<SUP>3</SUP> m<SUP>−3</SUP>). Overall, SMAP showed a dry bias (−0.0460m<SUP>3</SUP> m<SUP>−3</SUP>) and AMSR2 had a wet bias (0.0418m<SUP>3</SUP> m<SUP>−3</SUP>); while ASCAT showed the least bias (0.0010m<SUP>3</SUP> m<SUP>−3</SUP>) among all the products.</P> <P>Each product was evaluated using TC metrics with respect to the different ranges of vegetation optical depth (VOD). Under vegetation scarce conditions (VOD<0.10), such as desert and semi-desert regions, all products have difficulty obtaining SSM information. In regions with moderately vegetated areas (0.10<VOD<0.40), SMAP showed the highest Signal-to-Noise Ratio. Over highly vegetated regions (VOD>0.40) ASCAT showed comparatively better performance than did the other products.</P> <P>Using the maximized R method, SMAP, ASCAT, and AMSR2 products were combined one by one using the GLDAS dataset for reference SSM values. When the satellite products were combined, R-values of the combined products were improved or degraded depending on the VOD ranges produced, when compared with the results from the original products alone.</P> <P>The results of this study provide an overview of SMAP, ASCAT, and AMSR2 reliability and the performance of their combined products on a global scale. This study is the first to show the advantages of the recently available SMAP dataset for effective merging of different satellite products and of their application to various hydro-meteorological problems.</P> <P><B>Highlights</B></P> <P> <UL> <LI> SMAP strongly agreed with the temporal dynamics of <I>in-situ</I> observations. </LI> <LI> All remotely sensed soil moisture products were sound over moderately vegetated areas. </LI> <LI> Over densely vegetated areas, ASCAT performed better than the other products. </LI> <LI> The maximized R method was utilized to show the importance of individual datasets. </LI> <LI> The SMAP-ASCAT combination performed better than the other combined products. </LI> </UL> </P>

      • KCI등재

        Successful Trastuzumab-Deruxtecan Rechallenge After Interstitial Lung Disease: A Case Report

        Vincent A. de Weger,Tim Schutte,Inge R.H.M. Konings,Catharina Willemien Menke-van der Houven van Oordt 한국유방암학회 2023 Journal of breast cancer Vol.26 No.5

        Trastuzumab deruxtecan (T-DXd) is used to treat human epidermal growth factor receptor 2-positive advanced breast cancer. Interstitial lung disease (ILD) is a severe adverse event associated with T-DXd. Current guidelines recommend permanent discontinuation of T-DXd after Common Terminology Criteria for Adverse Events (CTCAE) grade ≥ 2 ILD. Here, we describe a case of successful rechallenge with T-DXd after CTCAE grade 2 treatment-induced ILD. After discontinuation of T-DXd, ILD was treated with steroids until complete resolution. Given the initial beneficial antitumor response, retreatment was discussed during disease progression. In a shared decision with the patient, T-DXd was restarted at the lowest registered dose, along with low-dose steroids. ILD did not reoccur. Importantly, both clinical and radiological responses to the treatment were observed, with an improvement in the patient’s quality of life. This case demonstrates that retreatment with T-DXd after a grade 2 ILD event is feasible and yields clinical benefit.

      • Determining the Best Immunization Strategy for Protecting African Children Against Invasive <i>Salmonella</i> Disease

        Jeon, Hyon Jin,Pak, Gi Deok,Im, Justin,Owusu-Dabo, Ellis,Adu-Sarkodie, Yaw,Gassama Sow, Amy,Bassiahi Soura, Abdramane,Gasmelseed, Nagla,Keddy, Karen H,Bjerregaard-Andersen, Morten,Konings, Frank,Aseff Oxford University Press 2018 Clinical infectious diseases Vol.67 No.12

        <▼1><P><B>Abstract</B></P><P><B>Background</B></P><P>The World Health Organization recently prequalified a typhoid conjugate vaccine (TCV), recommending its use in persons ≥6 months to 45 years residing in typhoid fever (TF)–endemic areas. We now need to consider how TCVs can have the greatest impact in the most vulnerable populations.</P><P><B>Methods</B></P><P>The Typhoid Fever Surveillance in Africa Program (TSAP) was a blood culture-based surveillance of febrile patients from defined populations presenting at healthcare facilities in 10 African countries. TF and invasive non-typhoidal <I>Salmonella</I> (iNTS) disease incidences were estimated for 0–10 year-olds in one-year age increments.</P><P><B>Results</B></P><P><I>Salmonella</I> Typhi and iNTS were the most frequently isolated pathogens; 135 and 94 cases were identified, respectively. Analysis from three countries was excluded (incomplete person-years of observation (PYO) data). Thirty-seven of 123 TF cases (30.1%) and 71/90 iNTS disease cases (78.9%) occurred in children aged <5 years. No TF and 8/90 iNTS infections (8.9%) were observed in infants aged <9 months. The TF incidences (/100 000 PYO) for children aged <1 year and 1 to <2 years were 5 and 39, respectively; the highest incidence was 304 per 100 000 PYO in 4 to <5 year-olds. The iNTS disease incidence in the defined age groups ranged between 81 and 233 per 100 000 PYO, highest in 1 to <2 year-olds. TF and iNTS disease incidences were higher in West Africa.</P><P><B>Conclusions</B></P><P>High burden of TF detected in young children strengthens the need for TCV introduction. Given the concurrent iNTS disease burden, development of a trivalent vaccine against <I>S.</I> Typhi, <I>S.</I> Typhimurium, and <I>S.</I> Enteritidis may be timely in this region.</P></▼1><▼2><P>A significant burden of typhoid fever in children aged <5 years in sub-Saharan Africa merits the introduction of typhoid conjugate vaccine at age 9 months, which coincides with the first dose of measles vaccine.</P></▼2>

      • KCI등재

        Probabilistic time-dependent sensitivity analysis of HPC bridge deck exposed to chlorides

        Pratanu Ghosh,Petr Konečný,Petr Lehner,Paul J. Tikalsky 사단법인 한국계산역학회 2017 Computers and Concrete, An International Journal Vol.19 No.3

        A robust finite element based reinforced concrete bridge deck corrosion initiation model is applied for time-dependent probabilistic sensitivity analysis. The model is focused on uncertainties in the governing parameters that include variation of high performance concrete (HPC) diffusion coefficients, concrete cover depth, surface chloride concentration, holidays in reinforcements, coatings and critical chloride threshold level in several steel reinforcements. The corrosion initiation risk is expressed in the form of probability over intended life span of the bridge deck. Conducted study shows the time-dependent sensitivity analysis to evaluate the significance of governing parameters on chloride ingress rate, various steel reinforcement protection and the corrosion initiation likelihood. Results from this probabilistic analysis provide better insight into the effect of input parameters variation on the estimate of the corrosion initiation risk for the design of concrete structures in harsh chloride environments.

      • SCOPUSKCI등재

        The Role of the Campus Outdoor Environment on University Student Mental Health

        Mallory Koning(Mallory Koning ),김준현(Jun-Hyun Kim),Fatemeh Saeidi-Rizi(Fatemeh Saeidi-Rizi ),Noah Durst(Noah Durst ) 인간식물환경학회 2022 인간식물환경학회지 Vol.25 No.3

        Background and objective: The mental health and wellness of university students has been a pressing concern in recentyears in the US and is becoming an even larger issue due to the COVID-19 Pandemic. Numerous studies have supportedthe idea that the natural environment can have a positive impact on mental health, but only a few studies focus on the roleof university outdoor campus environments on student's mental health. The main purpose of this study is to investigatethe correlations between university student mental health and their campus's outdoor environment. Methods: An online survey was designed and distributed to students at Michigan State University, USA. Students wereasked questions about their overall mental well-being, as well as questions about their environmental perceptions, outdooractivity, views to nature through windows and safety concerns regarding their outdoor campus environment. Results: The major findings indicate a significant difference in mental health scores for windows in living quarters, wherestudents with living quarter windows had better mental health scores (MHS) than students without living quarter windows. This study also found a marginally significant difference in MHS for students with classroom windows. Other results of thisstudy include a significant difference in MHS for students' perception of safety on campus, outdoor work time, andperception of greenspace on campus. Conclusion: Future campus planner, landscape architects, university planners, and student counselors will use this studyto determine what kinds of outdoor spaces should be created and used to improve the well-being of students.

      • SCIESCOPUSKCI등재

        Measuring hull girder deformations on a 9300 TEU containership

        Koning, Jos,Schiere, Marcus The Society of Naval Architects of Korea 2014 International Journal of Naval Architecture and Oc Vol.6 No.4

        A 9300 TEU container carrier was equipped in 2006 with instrumentation aimed at wave induced accelerations, and motions. In 2010 the system was extended with strain sensors to include structural loads. Section loads for vertical bending could be readily obtained but the originally intended derivation of horizontal bending and torsion from the measured strains was found to be unreliable. This paper addresses an alternative approach that was adopted in the post processing of results. In particular the concept to use acceleration sensors to capture global hull deformations along the length of the hull, and the use of a data fusion procedure to obtain section loads from combined sensor data and finite element calculations. The approach is illustrated by comparison of actually measured accelerations and local strains with values obtained from the data fusion model. It is concluded that the approach is promising but in need of further validation and development. In particular the number and shapes of the modes used may not have been sufficient to represent the true deflection and thus strain distributions along the high loaded areas.

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