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      • Translation and Formation of Style in the Modern Japanese Novel

        KOMORI, Yoichi 이화여자대학교 이화인문과학원 2013 탈경계인문학 Vol.6 No.3

        This paper examines the role of translation in modern Japanese literature. The formation of the modern novel in Meiji Japan is deeply connected to the style of translation. The uniqueness of modern Japanese literature is revealed when the personhood of aspects other than personal pronouns within the language are intentionally emphasized. The emphasis on personhood was influenced during the Meiji Period among intellectuals of the culture and style of translation. Morita Shiken, who is called the king of translation, clearly called attention to the new contemporary texts and readers. The direction of his stylistic revolution became much clearer after he took clues from translated novels. He rejected the conventional stereotypical expressions used when describing a condition or object. Shiken’s experimental style cooperates with Futabatei Shimei’s translations creating territory for expressions and also draws a clear line with the style of novels in the past. Through its concern with the individuality of the textual world, the limitations, and individuality of the characters, the modern novel was able to acquire the structure of narrative. The central focus of the translation work in modern Japan and also in other East Asian country was the establishment of a space for new writing. The superficial difference between styles that tried to combine the written word with the spoken or the slang with the elegant, the classical Chinese style, or the imitation of the classical style was not important. The common understanding of expression concealed behind these superficial differences is that we should comprehend the dynamic movement in the border expressions of this age.

      • KCI등재

        Molecular Mechanism of Runx2-Dependent Bone Development

        Komori, Toshihisa Korean Society for Molecular and Cellular Biology 2020 Molecules and cells Vol.43 No.2

        Runx2 is an essential transcription factor for skeletal development. It is expressed in multipotent mesenchymal cells, osteoblast-lineage cells, and chondrocytes. Runx2 plays a major role in chondrocyte maturation, and Runx3 is partly involved. Runx2 regulates chondrocyte proliferation by directly regulating Ihh expression. It also determines whether chondrocytes become those that form transient cartilage or permanent cartilage, and functions in the pathogenesis of osteoarthritis. Runx2 is essential for osteoblast differentiation and is required for the proliferation of osteoprogenitors. Ihh is required for Runx2 expression in osteoprogenitors, and hedgehog signaling and Runx2 induce the differentiation of osteoprogenitors to preosteoblasts in endochondral bone. Runx2 induces Sp7 expression, and Runx2, Sp7, and canonical Wnt signaling are required for the differentiation of preosteoblasts to immature osteoblasts. It also induces the proliferation of osteoprogenitors by directly regulating the expression of Fgfr2 and Fgfr3. Furthermore, Runx2 induces the proliferation of mesenchymal cells and their commitment into osteoblast-lineage cells through the induction of hedgehog (Gli1, Ptch1, Ihh), Fgf (Fgfr2, Fgfr3), Wnt (Tcf7, Wnt10b), and Pthlh (Pth1r) signaling pathway gene expression in calvaria, and more than a half-dosage of Runx2 is required for their expression. This is a major cause of cleidocranial dysplasia, which is caused by heterozygous mutation of RUNX2. Cbfb, which is a co-transcription factor that forms a heterodimer with Runx2, enhances DNA binding of Runx2 and stabilizes Runx2 protein by inhibiting its ubiquitination. Thus, Runx2/Cbfb regulates the proliferation and differentiation of chondrocytes and osteoblast-lineage cells by activating multiple signaling pathways and via their reciprocal regulation.

      • SCIESCOPUSKCI등재

        UNBOUNDEDNESS OF THE TRILINEAR HILBERT TRANSFORM UNDER THE CRITICAL INDEX

        Komori-Furuya, Yasuo Korean Mathematical Society 2021 대한수학회지 Vol.58 No.5

        Demeter [1] and Kuk and Lee [5] proved the unboundedness of the trilinear Hilbert transforms H<sub>a,b,c</sub> under the critical index 1/2 for some parameters a, b and c. We show the unboundedness of H<sub>a,b,c</sub> for any parameters.

      • KCI등재

        Automatic Adaptive Space Segmentation for Reinforcement Learning

        Komori, Yuki,Notsu, Akira,Honda, Katsuhiro,Ichihashi, Hidetomo Korean Institute of Intelligent Systems 2012 INTERNATIONAL JOURNAL of FUZZY LOGIC and INTELLIGE Vol.12 No.1

        We tested a single pendulum simulation and observed the influence of several situation space segmentation types in reinforcement learning processes in order to propose a new adaptive automation for situation space segmentation. Its segmentation is performed by the Contraction Algorithm and the Cell Division Approach. Also, its automation is performed by "entropy," which is defined on action values’ distributions. Simulation results were shown to demonstrate the influence and adaptability of the proposed method.

      • KCI등재
      • KCI등재

        Recent updates on the management of autoimmune hepatitis

        ( Atsumasa Komori ) 대한간학회 2021 Clinical and Molecular Hepatology(대한간학회지) Vol.27 No.1

        Autoimmune hepatitis (AIH) is an immunoinflammatory chronic liver disease with dynamic and rather heterogeneous disease manifestations. A trend of increasing prevalence of AIH has been observed worldwide, along with a relative increase in the percentage of male patients. AIH is characterized and diagnosed based on serum biochemistry and liver histology: elevated aminotransferases and serum immunoglobulin G (IgG), the presence of serum anti-nuclear antibody or anti-smooth muscle antibody, and interface lympho-plasmacytic hepatitis. Clinical manifestations differ among disease subtypes with distinct time-frames, i.e., AIH with a chronic insidious onset, and acute-onset AIH (the diagnosis of which is often challenging due to the lack of typical serum findings). The absence of disease-specific biomarkers or histological findings may expand the disease phenotype into drug-induced AIH-like liver injury. Corticosteroids and azathioprine are recommended first-line treatments for AIH. The complete normalization of aminotransferases and serum IgG is an essential treatment response to ensure long-term overall survival. An incomplete response or intolerance to these drugs is considered an indication for second-line treatment, especially with mycophenolate mofetil. Lifelong maintenance treatment is required for the majority of patients, but the few who achieve prolonged and stringent biochemical remission with lower alanine aminotransferase and IgG within the normal range may be able to discontinue the medications. In the future, the quality of life of AIH patients should be managed by personalized medicine, including the appropriate selection and dosing of first-line therapy and perhaps alternating with potential therapeutics, and the prediction of the success of treatment withdrawal. (Clin Mol Hepatol 2021;27:58-69)

      • In Search of Regional Governance in East Asia: Processes and Outcomes

        Yasumasa Komori 서울대학교행정대학원 2013 Asian Journal of Political Science Vol.20 No.3

        This article employs the concept of ‘regional governance’ to analyze both the processesand outcomes of the emerging regional institutional arrangements in East Asia. It arguesthat while ASEAN has played a significant role in creating and sustaining the ‘processes’of wider East Asian regional governance efforts, the level of achievement in translatingthese processes into tangible ‘outcomes’ remains severely constrained by great powerrivalry, especially between Japan and China. By focusing on the areas of trade andfinance, this article argues that the varying levels of outcomes between these two issueareas can be explained primarily by the degree of convergence between Japanese andChinese interests. In particular, while Japan and China have a shared interest incontributing to the promotion of regional financial stability, they strongly disagree overthe appropriate form and contours of a trade governance system.

      • SCOPUSKCI등재

        The New Dynamics of East Asian Regional Economy: Japanese and Chinese Strategies in Asia

        ( Yasumasa Komori ) 인하대학교 국제관계연구소 2006 Pacific Focus Vol.21 No.23

        The Japan-led flying-geese pattern of economic development has become obsolete as an accurate description of the pattern of economic relations in East Asia. Meanwhile, the rise of China as the world`s production platform has become the most significant factor in transforming the East Asian regional economy. Although the Asian financial crisis served as a major catalyst for the emergence of ASEAN+3, the China factor looms increasingly important in the subsequent development of East Asian regionalism. Despite its enhanced position in the region, however, China`s new role in East Asia is clearly different from the role that Japan played at the zenith of its economic prosperity. While Japan`s economic engagement in Asia was based on economic penetration by Japanese multilateral firms, China`s rapid growth is still predicated upon foreign capital and technology. China`s strength lies in its ability to open up its economy for trade and investment. In trade negotiations with ASEAN, China has taken the lead, surpassing Japan, a country constrained by domestic politics. However, Japan remains an important partner for ASEAN countries, not only in providing financial and developmental assistance, but also in hedging against China`s dominance.

      • Proposal and Use of a Void Model for the Simulation of Ductile Fracture Behavior in Material Forming

        Kazutake Komori 한국소성가공학회 2010 기타자료 Vol.2010 No.6

        In this study, a ductile fracture model derived from a microscopic point of view is proposed and is proved to be effective in the simulation of material forming. First, a method of predicting ductile fracture is proposed using a model from a microscopic point of view. The relationship between the void volume fraction and the strain to fracture calculated from the model, agrees well with the relationship obtained from the Thomason’s model of internal necking. Next, a new computer program, based on a conventional computer program for the finite-element method, with which the behavior of crack growth after ductile fracture can be analyzed, has been proposed. The condition whereby a material is divided into two materials upon material forming has been simulated by the proposed ductile fracture model and the proposed new computer program. Finally, the simulation of ductile fracture behavior in material forming is performed, and the validity of our proposed model is clarified by comparing the analytical results with the experimental results.

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