한의진단명과 진단요건의 표준화 연구 III : 3차년도 연구결과 보고

최선미,양기상,최승훈,박경모,박종현,심범상,김성우,노석선,이인선,정진홍,이진용,김달래,임형호,김윤범,박성식,송태원,김종우,이승기,최윤정,신순식 한국한의학연구원 1997 한국한의학연구원논문집 Vol.3 No.1

The diagnostic requirements were suggested and explained regarding the systems of differentiation of symptoms and signs in the third year study of standardization and unification of the terms and conditions used for diagnosis in oriental medicine. The systems were as follows : - analyzing and differentiating of epidemic febrile disease - analyzing and differentiating in accordance with the Sasang constitution medicine based on four-type recognition - differentiation of disease according to pathological changes of Chong and Ren channels - standards for diagnosis of women's disease - standards for diagnosis of children's disease - standards for diagnosis of motor and sensor disturbance (-muscle. born, joint, etc.) - standards for diagnosis of neuropsychiatric disease - standards for diagnosis of five sense organ disease - standards for diagnosis of external disease The indivisual diagnosis pattern was arranged by the diagnostic requirements in the following order : another name, notion of diagnosis pattern, index of differentiation of symptoms and signs, the main point of diagnosis, analysis of diagnosis pattern, discrimination of diagnosis pattern, prognosis, a way of curing a disease, prescription, herbs in common use, disease appearing the diagnosis pattern, documents. The standards for diagnosis of each disease was arranged by the diagnostic requirements in the following order : another name, notion of disease, the main point of diagnosis, analyzing and differentiating of disease, analysis of disease, discrimination of disease, prognosis, a way of curing and prescription of disease, disease in western medicine appearing the disease in oriental medicine, documents.

호산구성 간농양 54예의 임상상

강혜련,권혁수,송우정,이상민,김태범,박혜경,장윤석,김윤근,조상헌,민경업,김유영 대한알레르기학회 2004 천식 및 알레르기 Vol.24 No.2

광원의 종류에 따른 콤포짓트레진의 중합도

윤태호,이용근,임범순,김철위 대한치과기재학회 2001 대한치과재료학회지 Vol.28 No.1

콤포짓트레진의 중합도와 속도는 광원의 종류와 광조사 시간에 따라 영향을 받는다. 현재 할로겐 램프를 중합에 많이 사용하고 있으나 전구의 수명이 짧고, 시간경과에 따라 광선의 출력이 감소하므로 중합도는 낮아져 물성이 감소하고 수복물이 실패할 가능성도 높다. 이를 개선하기 위하여 콤포짓트레진 중합에 사용할 수 있는 LED (blue light emitting diode) 와 플라즈마 아크 기술이 소개되었다. 이 실험에서는 3 종의 광원(할로겐 램프, LED 및 플라즈마 아크) 에서 광조사시간을 달리하여 광에너지의 총량을 변화하는 조건으로 점주도가 서로 다른 3 종의 콤포짓트레진에서 깊이에 따른 중합도를 측정하여 각 광원의 효율성을 상호 비교하였다. 할로겐 램프, LED 및 플라즈마 아크 조사기로 광에너지 총량이 각각 8J/㎤와 16J/㎤ 이 되도록 중합하고 표면에서 1, 2, 3 및 4mm 위치에서 100㎛ 의 두께로 절단하였다. 시편 두께가 50~70㎛ 가 되도록 연마하고 FT-IR 로 표준기선법에 따라 중합직후의 중합도를 측정하였다. 중합방법 및 광조사 부위에서 깊이에 따른 평균 중합도를 계산하여 3 원 분산분석 및 Scheffe 의 방법에 따라 유의수준 0.05 에서 검정하였다. 이 실험에서 다음과 같은 결과를 얻었다. 재료, 깊이 및 광조사 시간 모두 전환율에 유의한 영향을 주었다(p〈0.01). 3 종 광원의 표층에서 1mm 깊이에서의 중합도는 저점도(RVN) 〉중점도(Z25) 〉응축형 콤포짓트레진(SRF) 순이었다(p〈0.05). 3종 광원의 중합도는 유의한 차이를 볼 수 없었다(p〉0.05). 3종의 조사광원 모두에서 광에너지 총량을 2배로 증가한 경우, 중합도는 2mm 깊이까지는 유의한 차이가 없었으나(p〉0.05), 3mm 부터는 광에너지 총량 증가에 따라 유의하게 증가하였다(p〈0.05).

잠재적 간성혼수 환자의 인지기능과 양성자 자기공명분광 소견과의 상관관계

김성윤,정범석,서동완,이정희,이 철 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.6

연구목적 : 잠재성 간성혼수 환자들의 신경인지기능 장애 정도와 기저 핵이나 두정엽 백질부에서의 자기공명분광 (proton MRS)으로 측정한 양성자 함유 화합물의 변화와의 상관관계를 조사하고자 하였다. 방법: 한국판 웩슬러 지능 검사(KWIS) 중 토막짜기나 기호 바꾸기, 그리고 번호잇기 검사를 적용하여 잠재성 간성혼수로 정의된 18명의 간경변 환자를 대상군으로 하고 20명의 정상인을 대조군으로 하였다. 복합주의력과 시각 정보 분석능력 측정을 위해 Vienna 전산화 신경인지기능 검사 중, Cognitrone 검사. 미세 협응 운동능력을 위해 Grooved pegboard 검사를 적용하였단 1.5 Tesla 임상용 자기공명 촬영기를 이용해 자기공련명 분광을 얻었으며 두정엽 백질부와 기저핵의 각각 2×2×2cm3 vocel에서의 myoinositol(ml), N-acetyl-L-aspartate(NAA). creative(Cr), choline(Cho) 등의 농도를 측정하고 Cr 농도에 대한 상대적 농도비율을 구하여 분석하였다. 결과: 1) 잠재성 간성혼수 환자들의 기저핵과 두정엽 백질부에서 Cho/cr 및 ml/Cr 비가 감소하였다. 2) 미세 협응 운동능력을 반영하는 Grooved pegboard 검사의 수행능력이 기저핵의 ml 및 두정엽 백질부의 Cho농도와 유의미한 역상관관계를 보였다(r= -0.59. p<.05). 3) Cognitrone 검사 중 정반응하는데 걸리는 평균시간은 두정엽 백질부의 NAA와 역 상관관계를 보였다(r= -0.55, p<.05) . 결론 : 잠재성 간성혼수 환자들의 특정 신경인지기능의 장애는 양성자 자기공명분광법으로 측정한 기저핵 및 두정엽 백질부의 신경화학적 변화와 상관관계를 보인다. 하지만 이러한 신경화학적 변화가 잠재성 간성 혼수의 근본적 병리 생리인지 2차적 변화인지를 규명하기 위해서는 질병의 경과에 따른 신경인지기능 및 양성자 자기공명분광 소견의 추적연구가 필요하며 비슷한 인지기능의 장애를 보이는 다른 신경퇴행성 질환과의 비교 연구가 필요하다. 0bjectives To investigate the relationship of neurochemical changes of brain in SCHE patients and the level of cognitive function, the authors measured hydrogen containing neurochemicals in two brain regions using 1H MRS, and compared those changes with the level of cognitive performances such as attention, visual analysis, or fine motor function. Methods ; A total of patients with liver cirrohosis were defined as SCHE, for they performed poorly(out of 1 SD of normative data) in more than one neuropsychological tests conventionally used(digit symbol and block design tests in KWIS, trail making test A and B). They were further evaluated in attentional ability and efficacy of visual analysis using Cognitrone subtest in Vienna Neurocognitive Test battery. Fine motor coordination were also measured by Grooved Pegboard test. Patients and 20 nodal controls underwent proton MRS study. Proton containg neurochemirals , such as myoinositol(mI) , N-acetrl-L-aspartate(NAA) , creating (Cr) , choline(Cho) were measured from 2*2*2cm3 voxel of basal ganglia and parietal white matter using 1.5 tesla dinical MRI/MRS system. The ratios of above metabolites to Cr were analyzed. Results : 1) Patients with SCHE showed reductions in Cho/Cr and ml/Cr in both basal ganglia and parietal white matter compared to normal subjects. 2) Performance of Grooved Pegboard test were negatively correlated with ml level of basal gang1ia and with Cho level of parietal white matter(r= -0.59, p<.05). 3) Mean time of correct responses in Cognitrone test skewed negative correlation with NAA level of parietal white matter(r= -0.55, p<.05). Conclusion : Certain neurocognitive disturbances in SCHE patients seemed to be related with neurochemical changes in basal ganglia or parietal white matter. To further elucidate the relationship of focal biochemical changes and neurocognitive deficits in SCHE patients, however, fo11ow-up study according to the illness stage must be performed. Studies on other disorders showing similar cognitive deficit patterns would be helpful.

利用者의 心理行態에 의한 公園綠地의 休養評價에 관한 硏究

金範洙,鄭玧洙 建國大學校 自然科學硏究所 1994 建國自然科學硏究誌 Vol.5 No.1

Green park was measured on value of evaluation of resorters. Based on accessability to green park, adequacey of usefulness and management and operation; these three points are analyzed in relation with resorters' psychology and behavior and characteristics of green park. Conclusions are drawn as follows: An approach of measuring factor of accessability was adopted to indentify inter-relation ship of between environmental features of green park and resorters' psychology and behavior. It was found that there was useful effect on evaluation of green park environment of large size. Green parks of large size has strong advantage of rest and recreation due to natural rich resources compare with urban forest. Size of green park and park facilities dominate and retain a great influence on frequency of resorters and scope of resorter's residence. Resorters of large parks can be divided into resorters from far distance and resorters of local vicinity. In order to enlarge useful effect of large green park, a proper measure should sought to display sufficient functions of favoring urban forest. It is found necessary to expand parking space and other facilities of conveniences for benefit of resortors to green parks. Resorters favoring green parks are seen very cooperative with management of large sized green parks. This phenomenon contribute much to preserving the environment better effectively.

두개외 경동맥 협착증에 대한 스텐트 삽입술의 추적 결과

윤영섭,홍범기,최동훈,김선호,김동익,김승민,장양수,심원흠 대한순환기학회 1998 Korean Circulation Journal Vol.28 No.11

UV-TiO₂광촉매 반응기를 이용한 미생물의 살균효과

김시욱,이정섭,정해광,박열,윤성명,유진철,이범규,이인화,박진열 조선대학교 환경공해연구소 1998 環境公害硏究 Vol.14 No.-

UV-TiO_(2) 반응기를 이용하여 Escherichia coli와 Aspergillus oryzae var. oryzae의 살균효과를 측정하였다. 254 ㎚에서 최대 14 watt의 자외선 방출량을 내는 램프를 원형 Pyrex유리관 중앙에 설치하였고 TiO_(2)는 석영관에 박막증착(Thin Film Coating)된 형태와 슬러리 형태로 나누어 회분식으로 살균정도를 측정하였다. E. coli에 대한 살균력은 1.7× 10^(7) cells/㎖에 대해 5분간 자외선 조사를 하였을 경우 2.0× 10^(2) cells/㎖으로 감소하였고, 자외선 조사와 함께 슬러리 형태의 TiO_(2)를 첨가하였을 경우에는 3.4× 10 cells/㎖으로, 자외선 조사와 함께 TiO_(2)가 석영관에 박막증착된 경우에는 7.6× 10^(2) cells/㎖으로 감소하였다. 한편 위와 같은 조건에 유리관 하부에서 기포를 주입후 11분 동안 자외선을 조사시킨 경우에는 1.3× 10^(2) cells/㎖으로, 자외선 조사와 함께 슬러리 형태의 TiO_(2)를 첨가하였을 경우에는 1× 100 cells/㎖으로, 자외선 조사와 함께 TiO_(2)가 박막증착된 경우에는 7.9× 10 cells/㎖을 나타내었다. 결국 UV-TiO_(2) 반응기에 사용되는 TiO_(2)가 슬러리 형태일 때 최대 살균효과를 나타내었으나 기포가 첨가되었을때는 오히려 살균에 장애를 받는 것으로 나타난 반면 석영관에 박막증착된 경우에는 기포가 첨가되는 것이 살균에 효과적인 것으로 관찰되었다. The killing effect of UV-TiO_(2) photocatalytic system on the Escherichia coli DH5-慣 and Aspergillus oryzae var. oryzae (KCTC 6095) was studied. The UV lamp which emits maximum 14 watts at 254 nm was set on the center of pyrex round glass tube. Two types of TiO_(2), one of which is slurry and another which is thin film coated form, were used to determine the killing effect. When UV was irradiated to 1.7 * 10^(5) cells/??of E. coli for 11 min, the living cell number decreased to 4.0 * 1.0^(0) cells/?? The effect of UV system together with slurried TiO_(2) was less than 1 cells/?? whereas that of UV-coated TiO_(2) system decreased to 7.1 * 10^(3) cells/?? To study the effect of bubble on the killing of microorganisms, air was bubbled to the bottom of glass tube. When 1.7 * 10^(5) cells/??were exposed to UV for 11 min in combination with air bubble, the living cell number decreased to 1.3 x 10^(2) cells/?? In the same condition except the addition of slurried TiO_(2), the living cells were 1 * 10^(2) cells/?? However, more cells could be killed by the system which consists of UV, coated TiO_(2), and air bubble (7.9 * 10^(1) cells/??. From these results, it was found that UV-slurried system is the most effective one, but its killing effect is not stimulated by air bubble. However, bubbling was very effective in the UV-coated TiO_(2) system.

광중합형 글라스 아이오노머 시멘트의 개발에 관한 연구

김철위,윤수한,임범순 대한치과기재학회 1998 대한치과재료학회지 Vol.25 No.1

The object of this study was to synthesize the experimental light-activated glass ionomer cement change of glass components such as aluminum, fluorine, calcium, and strontium. To reinforce the glass ionomer cement, additions of metallic powder, ceramic powder, and light-activated composite resin to glass ionomer cements were performed. Radiopacity, comprehensive strength, bond strength, fracture toughness, sloubility, and cytotoxicity of the various experimental glass ionomer cements were investigated. From the experiment, the following results were obtained: 1. Experimental light-activated glass ionomer cement showed similar physical and mechanical properties to commercial glass ionomer cement. Radiopacity, resistance of solubility, fracture thoughness, and compressive strength of the experimental cement were superior to those of commercial cements, but bond strength and biocompatibility of the experimental cement were inferior to commercial cements. 2. Addition of amalgam powder to light-activated glass ionomer cement resulted in the lower compressive strength and fracture toughness, but addition of aluminium powder resulted in the enhanced the fracture toughness. 3. Addition of alumina powder (Al₂O₃) could enhance the compressive strength and fracture toughness of the glass ionomer cement without sacrificing of the esthetic property. 4. Physical mixing light-activated glass ionomer cement with light-activated composite resin could enhanced the physical properties except for bond strength.

Simulation Model을 利用한 自然景觀과 建築物의 相關性에 關한 硏究

金範洙,鄭玧洙 建國大學校 自然科學硏究所 1995 建國自然科學硏究誌 Vol.6 No.-

本 硏究는 自然景觀을 배경으로 建築物의 形態와 규모를 合成하여 작성한 景觀 Simulation Model을 이용하여 自然景觀과 建築物과의 調和性을 平價하에 있어서 景觀構成要素와 景觀評價特性과의 相互關係를 究明하기 위하여 수행되었다. 寫眞合成에 사용한 自然景觀과 建築物은 1994年 7月부터 8月에 걸쳐서 撮影하였으며, Simulation Model에 5段階 尺度에 의한 心理測定法을 適用하여 1994年 8月에 評價하였다. 이번 硏究의 주요 內容은 自然景觀과 建築物과의 調和性을 모색하기 위한 문제점의 제기와 아울러 代案을 제시하였으며, 그 결과를 요약하면 다음과 같다. 1) 양호한 自然景觀에 建築物을 도입하게 되면 어떠한 형태이든 負의 상관이 나타나는 것으로 판명되었다. 2) 전반적으로 中層의 建築物이 高層의 建築物에 비하여 高度의 경관적 評價値를 보이고 있음이 밝혀졌다. 3) 建築物의 占有率과 導入 建物의 棟數가 증가함에 따라 綜合的 景觀性 및 自然性의 평가치는 저하된다. 4) 建築物이 自然景觀을 해치는 경향을 적게 하고 相互 調和를 도모하는 방법으로서 다음과 같은 사항을 제시코자 한다. ① 建築物의 높이를 낮게 제한한다. ② 규모에 있어서도 建築物의 시각적 점유율이 15% 범위를 초과하지 않도록 한다. ③ 配置形態는 連立形式으로 建築하거나 또는 建築物의 幅을 약간 넓도록 설계한다. ④ 視覺的으로 棟數를 적게 한다. The aim of this study was to explain the relationship between the landscape organization and evaluating factors to harmonize the buildings with natural landscape using the landscape simulation models controled the form and size of buildings and obtain some knowledges about the introduction of buildings into natural landscape. Through this study, the results were summerized as follow. It was proved that the introduction of buildings into good natural scenery, whatever form they might be had negative effect. It was revealed that the multistoried building, overall showed a high value of scenery in comparision with the high-rise building. As the occupancy rate of the building and the number of buildings increased, the evaluation of comprehensive scenery and natural quality became low. To attempt the harmony between the building and natural scenery to reduce the impact that the former had on the latter, an attempt is made to present the following matter; ① The hight of the building should be restricted to its low hight. ② The visual occupancy rate of the building should be made be within 15 percent in terms of its size. ③ The layout form of the building is in the form of the tenement house or the width of the building should be somewhat widely set. And, ④ The visual number of building should be made low.

광조사 방법에 따른 치과용 심미수복재의 중합수축

윤태호,이용근,임범순,김철위 대한치과기재학회 2000 대한치과재료학회지 Vol.27 No.4

Dental resin composites were introduced commercially in the mid-1960s for the restoration of anterior teeth. Since their advent, resin composites have undergone significant development, which continues to improve the longevity and application of resin composite restorations. Despite the development of new dentin-bonding agents, no system is currently available that completely withstands the formation of contraction gaps at the cementum/dentin-restoration junction, due to the unavoidable polymerization shrinkage of the resin composite during setting, therefore, a major aim of this study was to minimize or control the polymerization shrinkage of composites allowing flow of resin during setting reaction. A thermal dilatometer (DIL 402C, TASC 414/3A Controller, Netzche, Germany) was used to measure and compare conventional continuous cure and pulse cure polymerization shrinkage of seven light curing dental composites and three compomers. For conventional cure, restorative material were polymerized for 2 minutes using VIP (Bisco, U.S.A.) with 400 ㎽/㎠ intensity. After then, further polymerization was allowed for next 12 minutes that total 14 minutes of shrinkage was measured. For pulse cure, material was pre-polymerized irradiating light for 5 seconds with 200 ㎽/㎠ and post-ploymerized 3 minutes later with 400 ㎽/㎠ for 2 minutes. 9 minutes were allowed for further polymerization that total 14 minutes of shrinkage was measured. Polymerization shrinkage ranged from 3.758 ㎛/㎜ (SYC) to 6.897 ㎛/㎜ (P60) for conventional cure and 4.026 ㎛/㎜ (FLT) to 6.996 ㎛/㎜ (SRF) for pulse cure. The highest difference between the two methods was found at EAN (2.713 ㎛/㎜), followed by F20 and CRA which showed significant differences of 2.133, 1.274 ㎛/㎜ respectively (p<0.05). The least difference was found at SYC (0.489 ㎛/㎜). Universal resin composite group showed the highest polymerization shrinkage (6.514±0873 ㎛/㎜), and flowable composite showed the least shrinkage (4.139 ㎛/㎜). Packable composite showed 5.090±1.906 ㎛/㎜, and compomers showed 6.129±2.652 ㎛/㎜.