Increased Urinary KIM-1 and Tubular KIM-1 Expression in IgA Nephroapathy (초)

( Mi Seon Seo ),( Soon Hyo Kwon ),( Moo Young Park ),( Soo Jung Choi ),( Jin Seok Jeon ),( Hyun Jin Noh ),( Jin Gook Kim ),( Dong Cheol Han ),( Seung Duk Hwang ) 대한내과학회 2010 대한내과학회 추계학술대회 Vol.2010 No.-

탄소나노튜브 캐소드의 전계방출 및 열화특성에 미치는 페이스트의 조성과 분위기 가스의 영향

김동희,김태식,정원섭,김광호,손영국,조영래 대한금속ᆞ재료학회 2006 대한금속·재료학회지 Vol.44 No.3

경주시민의 여가활동유형과 여가만족간의 관계

김홍석,이동수,조국래 경주대학교 지역개발연구소 2000 地域開發論叢 Vol.- No.3

The purpose of this study was to grasp the relationship between of leisure of leisure activity and leisure satisfaction of the workers. more details, The issues of this research was to hold the relationship between styles of activities which are composed of sport, hobby, sight seeing, travelling, listening, social, educational activities and leisure satisfaction being organized of psychological, educational, social, physiological, relaxational, and environmental satisfaction. Subjects of this study were sampled 412 workers. Statistics employed in this research were analysis of covariance(ANCOVA) and multiple classification analysis(MCA). Based on the procedures and results, the following conclusions were warranted. First, the styles of leisure activity of the citizens in Kyongju were influenced on the social leisure satisfaction, and the social leisure satisfaction was differed from according to styles of leisure activities of the citizens in Kyongju. and then it was revealed high on sports activity. Second, 송 styles of leisure activity of the citizens in Kyongju were influenced on the physical leisure satisfaction, and the physical leisure satisfaction was differed from according to styles of leisure activities of the citizens in Kyongju. and then it was revealed high on social intercourse activity. Third, the styles of leisure activity of the citizens in Kyongju were influenced on the psychological leisure satisfaction, and the psychological leisure satisfaction was differed from according to styles of leisure activities of the citizens in Kyongju. and then it was revealed high on sports activity. Forth, the styles of leisure activity of the citizens in Kyongju were influenced on 송 educational leisure satisfaction, and the leisure satisfaction was differed from according to styles of leisure activities of the citizens in Kyongju and then it was revealed high on sights seeing activity. Fifth, the styles of leisure activity of the citizens in Kyongju were influenced on the relaxational leisure satisfaction, and the relaxational leisure satisfaction was differed from according to styles of leisure activities of the citizens in Kyongju and then it was revealed high on sports activity. Sixth, the styles of leisure activity of the citizens in Lyongju were influenced on the environmental leisure satisfaction, and the environmental leisure satisfaction was differed from according to styles of leisure activities of the citizens in Kyongju and then it was revealed high on sports activity.

세마포아 연산을 포함한 병렬 프로그램의 오류수정을 위한 추적 화일 분석

김동국,전용기 慶尙大學校 1992 論文集 Vol.31 No.2

Parallel programs may show errors generated by incorrect interactions between concurrintly executing processes, as well as logical ones which are similar to in sequential programs. Specifically, it shows nondeterministic executions by races for shared variables during program executions with anonymous synchronizations. To analyze the races, we can obtain the safe orders which are deterministic execution orders through observing the partical orders of events in a sequential trace. The main goal of the paper is an implemintation of the algorithms which determine a set of the safe orders in a given trace file.

목재 건조공정 배기가스의 특성에 관한 연구

장정국,박동근,김미란 東西大學校 2001 동서논문집 Vol.7 No.-

This study was performed to provides the characteristics of flue gas producted from wood drying process. Generally, the flue gas producted from wood drying process was elutriated with a large amount of moisture and odorous compounds such as BTX and ethanol. Therefore, it is very difficult to select and design of flue gas control devices. In order to optimum design and selection of control devices, have to investigate the various parameters such as temperature, moisture contents and flow rate of flue gas. When the wood is almost dry(<10% moisture), the moisture contents of flue gas were very high (about 18.2 V/V%). It is equivalent to 320 ton/day moisture as 1100 ton wood/day induce to the drying process. The temperature of flue gas ranges from 140℃ to 150℃ in each dryer stack with exception of the input site of wood(about 110℃). Thevelocity of flue gas In each stack ranges from 1.7 to 9.7 m/sec. About 40 VOCs in the flue gas were analyzed, and the concentrations of major VOCs(ppm) were as follows respectively; benzen: 0.054∼0.052, toluene: 1.011∼2.547, ethylbenzen: 0.472∼2.023, m,p-xylene: 0.504∼3.245, styrene: 0.015∼0.148, o-xylene : 0.271∼1.097, ethanol: 11.2∼32.5, α-pinene: 0.908∼10.578, β-pinene: 0.982∼14.278.

X-선 조사를 받은 흰쥐망막 빛감각세포의 미세구조

고정식,박동분,양남길,안의태,박경호,김진국 대한해부학회 1993 Anatomy & Cell Biology Vol.26 No.3

15주간의 신체 활동 증진 프로그램이 여자 대학생의 신체 조성 및 혈중 지질 농도에 미치는 영향

장지훈,성기홍,김남익,조국래,이동수 한국유산소운동과학회 2002 대한스포츠융합학회지 (jcses) Vol.6 No.1

The purpose of this study was to develop the lecture model as liberal arts which have the positive effects to promote physical activity and to decrease obesity-dated variables. Subjects in this study were women university students, and they were divided into two groups to voluntary applying; one was tennis group (n=10), the other table tennis group (n=10). Physical activity promotion program in this study was practiced one time a week, 130 min. one time with the intensity under 83% predicted HR max for 15 weeks. Anthropometrics, body fat(%), blood lipid profile were measured before and after attending the program, respectively. After 15-week-physical activity promotion program, body weight, BMI, WHR, body fat(%), total cholesterol concentration, triacylglyceride concentration were decreased significantly in both groups (p<.5). Resting heart rate was decreased significantly only in tennis group (p<.5). No significance was shown in systolic and diastolic blood pressure to both groups.

정신분열병 환자의 우울증에서 Paroxetine과 삼환계 항우울제 병용치료

심주철,공보금,박정환,윤영란,신재국,김정익,안동성,김용관,차인준,김영훈 大韓神經精神醫學會 1997 신경정신의학 Vol.36 No.4

저자들은 마산동서병원에 입원중인 우울증이 동반된 정신분열증 환자 10명을 대상으로 사용중인 항정신병약물에 paroxetine과 저용량의 삼환계 항우울제를 6주간 병용투여한 후 우울증상에 대한 효과와 치료의 안전성 및 약물상호작용을 알아보았다. Paroxetine은 고정량의 항정신병약물과 삼환계 항우울제에 부가하여 일일 20㎎을 6주간 병용하게 하였으며, 임상상태는 HDRS, HARS, UKU Side Effect Rating Scale등의 평가척도를 사용하여 평가하였다. 또한 약동학적 약물상호작용은 삼환계 항우울제들의 혈장농도를 HPLC로 측정하여 분석하였다. 결과는 다음과 같다. 1) 10명의 전체 대상환자에서의 HDRS 평균점수는 TCA와 paroxetine 병용투여 6주후에 통계적으로 유의하게 감소되었다. 이중 40%의 환자에서는 병용투여 6주후에 HDRS 점수상 50% 이상의 감소를 보여, 일부의 환자들에서는 정신분열병에 동반된 우울증상의 치료에 소량의 삼환계 항우울제와 paroxetine의 병용치료가 효과가 있음을 확인하였다. 2) 두 명의 환자에게서 심각한 약물독성이 발생하였다. 이중 한 명은 삼환계 항우울제의 높은 혈중농도로 인한 항콜린성 위기(anticholinergic crisis) 소견을 보였으며, 다른 한 명은 인지기능 및 의식수준은 명료하였으나 망상과 환각증상이 약화되는 소견을 보였다. 따라서 본 연구에서 시도된 복합적 약물치료의 경우, 삼환계 항우울제의 혈중농도의 측정을 포함한 세심한 임상적 추적이 필요하다고 생각된다. 3) 기저치의 amitriptyline과 그 대사물인 nortriptyline의 농도합. imipramine과 대사물인 desipramine의 농도합은 각각 47.8-226.5ng/㎖. 80.5-395.6ng/㎖였으며 일반적으로 이들 약물들의 단독사용시에 문헌에 보고된 혈중농도를 훨씬 상회하고 있었다. 이는 병용투여된 항정신병 약물 약시 강력한 CYP2D6 효소억제제로서 기저치의 삼환계 항우울제들의 혈장농도를 이미 상당히 증가시켰던 것으로 판단되며, 그러한 결과로 인해 본 연구에서는 paroxetine이 이전의 문헌보고들과는 달리 뚜렷하게 삼환계 항우울제들의 혈장농도를 증가시키지 못하였다. 본 연구는 SSRI와 삼환계 항우울제의 병합 투여가 우울증의 개선 효과를 빠르게 하고, 치료역을 넓히고, 약물상호작용의 결과 paroxetine이 삼환계 항우울제의 혈중농도를 증가시킨다는 기존의 연구결과를 이용하여 정신분열병 우울증상의 치료에 parotextine과 소량의 삼환계 항우울제를 병용하는 방법을 시도해 본 연구이다. 저자들은 이러한 약물치료가 일부의 환자들에게서 효과가 있음을 관찰하였으나, 항정신병약물과 삼환계 항우울제를 병용투여 할 경우는 물론 이에 paroxetine과 같은 선택적 세로토닌 재흡수 억제제를 병용할 경우 복합약물상호작용의 결과로 약물독성의 위험성이 크며 세심한 주의가 필요함을 경험하였다. Depression is well-known to comorbid with several psychiatric disorders. Many schizophrenics also suffer from depression in the course of their illness. Combined therapy of SSRI and tricyclic antidepressants were reported to have benefits in some depressed patients. Paroxetine, a potent CYP2D6 inhibitor, increases the blood levels of tricyclic antidepressant markedly. Using paroxetine, we tried this combined therapy in the treatment of depressive symptoms in 10 chronic schizophrenic inpatients and evaluated its efficacy and drug interactions between paroxetine and tricyclic antidepressants. The following results were obtained : 1) The mean score of Hamilton's Depression Rating Scale(HDRS) was reduced significantly after 6 weeks-trials of this combined therapy for the mild depressive symptoms in 10 chronic schizophrenics. In four patients, 50% or more reductions in the scores of HDRS were noticed at final evaluation. 2) Two among our 10 subjects experienced severe toxic behavioral problems. Anticholinergic crisis with toxic confusion due to high blood levels of tricyclics was found in one patient and the other showed rapid clinical deterioration in his psychotic symptoms such as delusion and hallucination without any consciousness alternation. 3) Baseline plasma levels of tricyclics before adding paroxetine were higher than expected in our chronic schizophrenic subjects maintained with their antipsychotic medications. Several antipsychotics were also known as a potent CYP2D6 inhibitors and to increase the blood levels of tricyclics. Because the blood levels of tricyclics had already increased significantly by the use of antipsychotics, adding paroxetine to antipsychotics and tricyclic antidepressant in our subjects could increase the blood levels of tricyclics not so much as previously reported in the literatures.

Bismuth-telluride Thermoelectric Nanoparticles Synthesized by Using a Polyol Process

Kim, KyungTae,Lee, Hye Moon,Kim, Dong Won,Kim, Kyong Ju,Lee, Gil Geun,Ha, Gook Hyun Korean Physical Society 2010 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.57 No.4

Sampling Time and pH-Dependences of Silicon Nanowire Ion-Sensitive Field-Effect Transistor-Based Biosensors

Kim, Seohyeon,Kim, Jungmok,Jang, Jungkyu,Mo, Hyun-Sun,Kim, Dong Myong,Choi, Sung-Jin,Park, Byung-Gook,Kim, Dae Hwan,Park, Jisun American Scientific Publishers 2017 Journal of nanoscience and nanotechnology Vol.17 No.5

<P>Silicon nanowire ion-sensitive field-effect transistor (SiNW ISFET) is widely used for the label-free detection and real-time analysis in chemical and biological experiments. However, hysteresis and dynamic transfer characteristic related to time dependence are main drawbacks of SiNW ISFET. By changing hold time (T-H), delay time (T-D), and pH level under aqueous environment, we explained mechanism of hysteresis and dynamic transfer characteristic through analyzing the electrical characteristics. We believe that the results found in this study are able to minimize the effects caused by hysteresis, which contributes to advanced biosensing experiment in the future.</P>