Catching Two Birds with One Stone: Development of Novel Avian Transgenic Animal Models for Agri-medicine

Kichoon Lee 한국동물생명공학회(구 한국동물번식학회) 2017 Reproductive & Developmental Biology(Supplement) Vol.41 No.2

Obesity caused by excessive fat accretion in adipose tissue or the whole body is a major health issue in a significant portion of the US population. Economically, the CDC estimates that the US spends $147 billion annually in extra health costs related to obesity. In the poultry industry, decreasing 1% of body fat in the chicken is valued at a total of $30 million per year. The recent advances in bioinformatics and DNA microarray technology allow rapid genetic analysis to take place on a genome-wide scale and have revolutionized the way specific diseases are studied. Our comparative analysis of microarray data across animal species led us to identify several novel adipose tissue-specific genes and demonstrate functions of these genes in adipose development. Because genetics and developmental aspects of adipocyte biology are highly conserved across species, animals including the quail provided excellent models to understand the function of these genes in adipocyte development and lipid metabolism. This approach of studying obesity promises to provide a better understanding of the underlying mechanisms responsible for obesity and to discover new candidate genes and their signaling pathways, leading to the development of more effective therapeutic and nutraceutical interventions.

MEROMORPHIC FUNCTIONS, DIVISORS, AND PROJECTIVE CURVES: AN INTRODUCTORY SURVEY

Yang, Kichoon 대한수학회 1994 대한수학회지 Vol.31 No.4

COMPLETE MINIMAL SURFACES AND PUNCTURED COMPACT RIEMANN SURFACES

YANG, KICHOON Korean Mathematical Society 1991 대한수학회지 Vol.28 No.2

어린상사(Younger Boss)가 구성원의 태도에 미치는 영향 : 심리적 계약위반과 리더 정당성의 역할

김기춘 ( Kim Kichoon ),김미경 ( Kim Mikyoung ),문재승 ( Moon Jaeseung ) KNU기업경영연구소 2021 기업경영리뷰 Vol.12 No.1

최근 능력 위주의 승진 문화 확산 등으로 인해 이른바 ‘나이 어린상사’가 늘고 있으나, 나이에 따른 서열 체계가 익숙한 직장인들은 이런 새로운 흐름에 상당한 스트레스를 받고 있는 것으로 나타났다. 어린상사와 같이 근무하는 것에 대해 구성원이 스트레스를 받는 가장 큰 원인은 바로 자신의 위치에 대한 ‘심리적 불안감’이라 할 수 있다. 이러한 심리적 불안감은 궁극적으로는 이직으로 연결될 수 있다. 그러나 이러한 어린상사의 영향에 관한 논의와 실증 연구는 거의 없는 실정이다. 따라서 본 연구는 어린상사에 대한 구성원의 심리적 계약위반 지각을 통해 직무열의에 미치는 과정을 탐색하고, 리더 정당성이 심리적 계약위반 지각에 미치는 조절영향을 탐색하고자 한다. 이에 따라 설정한 가설을 검증하기 위해 다양한 기업에 근무하는 254명으로부터 수집한 설문을 분석하였다. 실증분석 결과 첫째, 어린상사는 구성원의 심리적 계약위반에 영향을 미치지 않았다. 둘째, 심리적 계약위반은 직무열의에 부정적 영향을 주었다. 셋째, 어린상사와 직무열의의 관계에서 심리적 계약위반의 매개효과가 확인되지 않았다. 넷째, 어린상사와 심리적 계약위반 관계에서 리더 정당성의 조절효과가 확인되었다. 연구결과를 바탕으로 이론적 및 실무적 시사점을 제시하면서 향후 연구방향을 제안하였다. Recently, the number of so-called “young bosses” has been increasing due to the spread of a promotion culture focused on ability, but it was found that office workers who are familiar with the hierarchy according to their age are under considerable stress from this new trend. The biggest reason why employees are stressed about working with a young boss is ‘psychological anxiety’ about their position. This psychological anxiety can increase the turnover rate and ultimately lead to retirement. However, there are few empirical studies on these young bosses. Therefore, this study seeks to explore the process that affects work engagement through the perception of organizational members’ psychological contract violations toward young bosses, and explores the moderating effect of leader legitimacy on the relationship between younger boss and psychological contract violations. For this, hypotheses were established based on previous studies. To verify the hypothesis, we collected and analyzed questionnaires from 254 employees working at various companies in Korea. As a result of empirical analysis, first, the young boss did not have a significant effect on the members’ psychological contract violation. Second, psychological contract violation had a significant effect on work engagement. Third, the mediating effect of psychological contract violation was not significant on the relationship between young boss and work engagement. Fourth, the moderating effect of the leader legitimacy on the relationship between the young boss and the psychological contract violation was significant. Based on the research results, theoretical and practical implications were discussed and future research directions were suggested.

<b>Concordance between molecular and morphology-based phylogenies of Korean Enhydrosoma (Copepoda: Harpacticoida: Cletodidae) highlights important </b><b>synapomorphies and homoplasies in this genus globally</b>.

KARANOVIC, TOMISLAV,KIM, KICHOON,LEE, WONCHOEL Magnolia Press 2015 Zootaxa Vol.3990 No.4

Morphological and molecular affinities of two East Asian species of <i>Stenhelia</i> (Crustacea, Copepoda, Harpacticoida)

Karanovic, Tomislav,Kim, Kichoon,Lee, Wonchoel Pensoft Publishers 2014 ZooKeys Vol.411 No.-

<P>Abstract</P><P>Definition of monophyletic supraspecific units in the harpacticoid subfamily Stenheliinae Brady, 1880 has been considered problematic and hindered by the lack of molecular or morphology based phylogenies, as well as by incomplete original descriptions of many species. Presence of a modified seta on the fifth leg endopod has been suggested recently as a synapomorphy of eight species comprising the redefined genus <I>Stenhelia</I> Boeck, 1865, although its presence was not known in <I>S. pubescens</I> Chislenko, 1978. We redescribe this species in detail here, based on our freshly collected topotypes from the Russian Far East. The other species redescribed in this paper was collected from the southern coast of South Korea and identified as the Chinese <I>S. taiae</I> Mu & Huys, 2002, which represents its second record ever and the first one in Korea. A fragment of the mtCOI gene was successfully PCR-amplified from two specimens of each species, which represents the first molecular data for this genus, and from additional 19 specimens belonging to six different species of other stenheliins from Korea and Russia. Reconstructed phylogenies confirm previously postulated monophyly of <I>Stenhelia</I> and polyphyly of the closely related genus <I>Delavalia</I> Brady, 1869. Average pairwise maximum likelihood distances between <I>S. pubescens</I> and <I>S. taiae</I> are only slightly above 10%, suggesting a very close relationship despite numerous newly discovered micro-morphological differences and despite macro-morphological similarities being probable plesiomorphies.</P>

유니버설 디자인 중심의 철도서비스 개선 방안 연구

김현주(Hyunju Kim),김기춘(Kichoon Kim),김진희(Jinhee Kim),배현옥(Hyunok Bae) 한국철도학회 2014 한국철도학회 학술발표대회논문집 Vol.2014 No.5

유니버설 디자인은 교통약자를 포함하여 다양한 계층의 사람들이 동등한 입장에서 동일한 방법으로 제품, 시설, 서비스 등을 사용 할 수 있게 설계하는 것이다. 선진국의 경우 30년 전부터 유니버설 디자인 개념을 적용한 연구 및 기술개발이 국가차원에서 진행되었으며, 국내의 경우 2009년 공공디자인과 유니버설 디자인의 통합된 개념이 정책적으로 확립되어 최근 경기도 유니버설 디자인 가이드라인 및 서울시 유니버설 디자인 국제세미나 등을 통해 유니버설 디자인의 의미와 가치가 확산 되고 실제 현장의 유니버설 디자인 적용에 많은 관심을 보이고 있다. 이에 본 연구에서는 철도 이용객을 위한 국내외 유니버설 디자인 적용사례를 조사하고 시설, 제도 등 서비스 분야별로 비교분석하여, 유니버설 디자인중심의 철도서비스 개선 방안을 도출하고자 한다. Universal design refers to broad-spectrum design ideas directed to provide products, facilities and services that are accessible equally to all walks of life embracing people with disabilities and those without them. As for advanced economies, the research and development on technologies based on the concept of universal design had been initiated on a government level about three decades ago. In Korea, the integrated concept of public design and universal design first met with the organized policies from 2009. Of late, the implications and values of universal design have been expanded through the Universal Design Guideline by Gyeonggi Province and the International Seminar on Universal Design by Seoul Municipality, heightening the public"s interest on how the concept can actually be applied on a working level. In this regard, this study aims to derive solutions on improving the railroad service centered on universal design by surveying the examples of universal designs for the railroad users in and outside of Korea and by comparing/analyzing the facilities and systems based on this concept by service sectors.

화차소요량 판단의 객관성 확보를 위한 적정 회귀일 산정

하오근(Ohkeun Ha),김기춘(Kichoon Kim),공현덕(Hyunduk Kong),최성필(Sungpil Choi) 한국철도학회 2013 한국철도학회 학술발표대회논문집 Vol.2013 No.11

화차 회귀일은 화차 소요 판단시 반영되는 지표로서 현재 철도공사에서 적용하고 있는 회귀일은 화물운송 및 운영특성을 고려하지 못하고 담당자의 주관적 판단 하에 목표조정 회귀일을 설정하여 적용하고 있는 상황이다. 이렇듯 화차 투자심의시 적용되고 있는 목표 조정 회귀일에 대한 객관성 부족에 대한 지적이 지속적으로 제기되고 있어 모두가 공감할 수 있는 객관적인 화차 회귀일 산정의 필요성이 증대되고 있다. 따라서 본 연구는 철도화물 운송에 활용되는 화차의 소요량 판단시 적용할 수 있는 화차 회귀일의 적용기준을 산정하는데 목적이 있다. 이를 위해 화차 회귀일의 개념 및 특징을 살펴보고 주요 화물역을 대상으로 회귀일 단축을 위한 의견조사를 통해 운영 및 인프라부분의 개선방안을 제시하였다. 끝으로 과거 5 년간(‘08~’12 년) 화차운송 프로세스별 소요시간 자료를 이용하여 차종별 회귀일을 산출하고 작업일수 변화에 따른 화차소요량 변화를 분석하였다. Wagon return days are an indicator reflected when the wagon quantity required is judged. The return days currently applied by Korean Railroad Corporation have been set as target adjusted return days under subjective judgment by persons in charge without considering the characteristics of freight transportation and operation. The lack of objectivity of the target adjusted return days applied to wagon investment deliberation has been continuously has been continuously pointed out and thus the necessity of calculations of objective wagon return days that can win the sympathy of everybody has been increasing. Therefore, the purpose of this study is to prepare the standard for application of wagon return days that can be applied when judging the required quantity of wagons utilized in railway freight transportation. To this end, the concept and characteristics of wagon return days were examined and measures to improve the operation of infrastructures were presented through a survey of opinions for shortening return days. Finally, return days by car type were calculated using data on time required by wagon transportation process over the last five years(2008~2012) and changes in wagon quantity required according to changes in the number of working days were analyzed.

A new species of <i>Harpacticella</i> Sars, 1908 ( Copepoda , Harpacticoida ), from a tidal pool on Jeju Island, Korea

Lee, Seunghan,Kim, Kichoon,Lee, Wonchoel Pensoft Publishers 2014 ZooKeys Vol.445 No.-

<P>Abstract</P><P>A new species of the genus <I>Harpacticella</I> Sars, 1908 is described from a tidal pool on Jeju Island, Korea. <I>Harpacticellajejuensis</I><B>sp. n.</B> is closely related to <I>Harpacticellaitoi</I> Chang & Kim, 1991, with regard to the structure of P1 exp-1 and enp-1, the length of P1 exp-1 and exp-2, and the setal number of the P5 exopod in males. However, the new species is clearly distinguishable from <I>Harpacticellaitoi</I> by the combined following characters: six setae on the P5 exopod in females, one naked seta on the inner margin of P1 exp-2, the short endopod of P1 compared to the exopod, and a naked long seta on the proximal inner margin of the P5 exopod of males. The mtCOI partial sequence is provided as a DNA barcode for the new species.</P>

Two unrecorded species of the family Comesomatidae Filipjev, 1918 (Nematoda: Araeolaimida) from Korea

Jung-Ho Hong,김형근,Kichoon Kim,이승한,이강현,WonchoelLee 국립생물자원관 2023 Journal of species research Vol.12 No.2

Two known species of the family Comesomatidae Filipjev, 1918 were collected from marine sediments of the sublittoral zone in the East Sea, Korea and described and illustrated. Dorylaimopsis variabilis Muthumbi, Soetaert and Vincx, 1997, which was originally described from the Kenyan coast in the Indian Ocean, is recorded from the East Sea, Korea for the first time; there are only slight differences in amphidial fovea turns, body length, body width and relative length of tail. Setosabatieria hilarula (De Man, 1922), Platt, 1985, which was originally described from the North Sea, is recorded from the East Sea, Korea for the first time; there are only slight differences in the number of precloacal supplements, the relative length of tail and the posterior portion of tail. We provide pictorial keys for determination of valid species in the genera Dorylaimopsis Ditlevsen, 1918 and Setosabatieria Platt, 1985. This is the first description of the genus Dorylaimopsis and Setosabatieria from Korean waters.