KI-180과 KI-188 칼슘조성물이 어린쥐의 성장발육에 미치는 영향

박승만(Seung-Man Park),성기승(Ki-Seung Seong),이종석(Jong-Seok Lee),이옥환(Ok-Hwan Lee),한찬규(Chan-Kyu Han) 한국식품과학회 2014 한국식품과학회지 Vol.46 No.3

본 연구에서는 KI-188 칼슘과 KI-180 조성물이 성장발육에 미치는 효과를 조사하였다. 시험기간중 KI-188 칼슘과 KI-180 식이군이 대조군 보다 성장률과 평균 식이섭취량은 증가하였다. 체장은 KI-188 칼슘과 KI-180 식이군이 대조군에 비해 평균 3.55 mm 더 길었고, 등뼈길이는 KI-180 식이군이 대조군 보다 통계적인 차이는 없었지만 0.5 mm 더 길었다. 대퇴골 무게는 KI-188 칼슘과 KI-180 식이군이 대조군에 비해 통계적으로 무거웠으며, 대퇴골길이는 대조군에 비해 각각 평균 0.89, 1.09 mm 더 길었다. 혈당, 총콜레스테롤 및 중성지방 농도는 차이가 없었고, 칼슘농도는 KI-188 칼슘과 KI-180 식이군 보다 대조군이 유의하게 높았다. 백혈구와 혈소판수는 차이가 없었고, 적혈구, 혈색소 및 헤마토크릿치는 대조군이 KI-188 칼슘과 KI-180 식이군 보다 통계적으로 높았다. ALP활성은 KI-180 식이군이 대조군 보다 통계적으로 높았고, osteocalcin농도는 KI-188 칼슘과 KI-180 식이군이 대조군에 비해 통계적으로 유의하게 높았다. 혈청 testosterone 농도는 KI-188 칼슘과 KI-180 식이군과 대조군 간에 차이가 없었다. IGF-1과 IGFBP-3 농도는 KI-180 조성물이 대조군 보다 각각 20%, 11% 정도 유의하게 더 높았다. 이상의 결과를 검토할 때 KI-188 칼슘과 KI-180 조성물은 어린쥐의 성장과 골격의 발달을 촉진시키고, 성장호르몬의 분비능을 양적으로 유도하여 전반적인 성장발육에 유효한 작용이 있는 것으로 사료된다. Herbs have active components that promote the growth rate of both animals and human. The KI-180 and KI-188 calcium food formulae contain Acanthopanacis cortex, Bombysis corpus and hoelen, seaweed calcium, chlorella extract, spirulina, colostrum powder, and other natural and functional components. We evaluated the growth-promoting effects of these formulae by analyzing the weight, femur and backbone, alkaline phosphatase, osteocalcin, testosterone, insulin-like growth factor (IGF)-1, and IGF binding protein-3 (IGFBP-3) of growing rats. Growing rats administered with KI-180 and KI-188 calcium showed the increase of body weight, body length, and femur weight and length of growing rats. In addition, administration of KI-180 and KI-188 calcium increased the alkaline phosphatase activity, the levels of osteocalcin and the growth hormones IGF-1 and IGFBP-3 of growing rats. The impact of KI-180 and KI-188 calcium on the physical development of growing rats suggests that the incorporation of these food formulae in the diets of growing children may promote the physical development.

직장 카르시노이드 종양에서 Ki-67 발현의 예후적 중요성

홍수민 ( Su Min Hong ),김유선 ( You Sun Kim ),문정섭 ( Jung Seop Moon ),김진남 ( Jin Nam Kim ),오명기 ( Myoung Ki Oh ),권선옥 ( Sun Ok Kwon ),정성연 ( Seong Yeon Jeong ),홍성우 ( Seong Woo Hong ),강윤경 ( Yun Kyung Kang ) 대한소화기학회 2013 대한소화기학회지 Vol.61 No.2

Background/Aims: Rectal carcinoid tumors can be resected with endoscopy, and it is important to assess their prognostic factors. We evaluated the potential of Ki-67 expression as a prognostic factor in rectal carcinoid tumors. Methods: We retrospectively reviewed the medical records of 37 patients with rectal carcinoid tumors who got endoscopic resection from January 2001 to January 2011 at Inje University Seoul Paik Hospital. We analyzed their endoscopic and histologic findings, Ki-67 expression, clinical outcome, and prognosis. Results: The mean age (±SD) of the patients was 56.3±10.7 years, and the male : female ratio was 3.6:1. The mean tumor size was 0.5±0.4 cm, 33 patients showed grade 1 tumors (89.2%) and the average Ki-67 expression was 0.7±1.2%. Thirty five patients underwent endoscopic mucosal resection, and two required endoscopic submucosal dissection. Eight patients had positive margins after resection, but no cases of lymphovascular invasion were identified. The median follow-up duration was 21.4±25.4 months, and no recurrences were observed. Conclusions: In low grade rectal carcinoid tumors which are lack of central depression on colonoscopy, the expression of a molecular marker of malignant potential, Ki-67, was low. Therefore, endoscopic resection seemed to be a safe and effective treatment for these tumors.

인체대장암에서의 Cyclin 유전자의 발현

백원기,서민호,서성일,문성희,박종욱,최병길,배옥석 대한대장항문학회 1996 Annals of Coloproctolgy Vol.12 No.2

RBL-2H3 세포에서 Spermine에 의한 히스타민 유리와 칼슘유입에 미치는 상백피의억제효과

채옥희,강경진,신인호,김영기,이무삼,전병득 대한해부학회 1994 Anatomy & Cell Biology Vol.27 No.2

여성 외음부에 발생한 선상 편평상피세포암종

김창옥,양기화,강석진,이안희,김병기,김선무 대한병리학회 1991 Journal of Pathology and Translational Medicine Vol.25 No.1

대학 운동클럽(Club)학생들의 체형. 신체구성에 관한 연구

한기문,박승옥 광운대학교 기초과학연구소 1997 기초과학연구소논문집 Vol.26 No.-

The purpose of this study is to find the somatotype and body composition of the students in sports clubs in our school, and the subjects of study are 169 students in all including 68 students in sports clubs(16 in table tennis club, 12 in tennis club, 14 in basketball club, 12 in keumdo club), 53 non-sports club students and 48 common students. The result of data analysis is as follows. 1. Somatotype The mean somatotype of the group in table tennis club is found to be endomorphic mesomorph of 3.59-4.51-3.10, that of the group in tennis club ectomorphic mesomorph of 2.97-4.67-3.18, that of the group in basketball club endomorphic mesomorph of 3.88-4.62-2.77, that of the group in baseball club endomorphic mesomorph of 4.13-4.81-2.12, and that of the group in keumdo club ectomorphic mesomorph of 2.98-4.35-3.20. The mean somatotype of all the group is found to be endomorphic mesomorph of 3.37-4.37-1.26. 2. Absolute Fat 1) % Fat The average of the group in table tennis club showed 18.97%, that of the group in tennis club 16.11%, that of the group in basketball club 19.83%, that of the group in baseball club 21.41%, that of the group in keumdo club 15.51%. 2) Absolute Fat The average of the group in table tennis club showed 12.51kg, that of the group in tennis club 10.02kg, that of the group in basketball club 13.83%, that of the group in baseball club 14.85kg, that of the group in keumdo club 9.98kg. 3. The comparison of the group in sports club with the group in non-sports club. The comparison of the two groups in somatotype showed that the group in sports club is much higher(p〈0.05) than the group in non-sports club in mesomorphic components. The comparison of absolute fat showed that the group in sports club is much more than the group in non-sports club only in lean body mass, and didn't show any striking difference in other components.

체육수업에서의 운동상해에 관한 연구

윤기대,양정옥,김영수 신라대학교 교육과학연구소 2004 교육과학연구 Vol.- No.9

중소도시 하수관거의 침입수량 및 수질오염 원단위 산정

김옥형,박승기,정재훈,임경호 公州大學校 工學硏究院 生産技術硏究所 2004 論文集 Vol.12 No.-

The volume of wastewater in combined sewers in study areas usually exceeds capacities of the sewer system or the treatment plant during storms. For this reason, combined sewer systems are designed to overflow occasionally and discharge excess waste water. The 6 monitoring sites were selected from two small cities near the Hongsung prefecture during over a rainy season. Monitoring was performed by collecting grab samples and by measuring the rainfall and flow rates during dry and wet seasons. Generally the flow rate of wastewater in combined sewers was rapidly decreased after 23:00 PM and gradually increased from 06:30 AM in all sites during the dry season. Due to monitoring and statistical analysis, the groundwater contributes on sewage volume increase (average 3.4-25.4% more) during experimental periods. Therefore, this research is focus on the investigation of the effects of stormwater and groundwater to combined sewer systems.

數學科 敎育의 發展 課題

강옥기 성균관대학교 기초과학연구소 1993 論文集 Vol.44 No.1

Korean Ministry of Education developed 6^th mathematics curriculum which will be executed from 1995. But this curriculum is very limited for the coming society which requires high technologies and informations. This study discussed and suggested some tasks to be solved to develop Korean mathematics education. The results are as follows : First, mathematics curriculum should be developed to emphasize problem solving, introduce discrete mathematics, and apply calculators and computers for mathematics instructions. Second, mathematics textbooks should be reformed to have creative features for various individual differences and courses. Regulations for teaching instruments and equipments should be revised for each school should purchase effective instruments and equipments for mathematics instruction. Third, evaluation directions of mathematics education in mathematics classrooms and for college enterance examinations should be changed to assess basic and principal mathematics knowledges, mathematical powers, and positive attitudes toward mathematics. Fourth, teachers' colleges should develop new curriculum focused on training good teachers. For the department of mathematics education, at least 9 units of compulsory and 6 units of optional mathematics education subjects are required.

국민학교에서의 임상 장학의 이용 가능성에 관한 연구

윤기옥 仁川敎育大學校 1987 論文集 Vol.21 No.1