The Direct Myocardial Depressant Effect of Naloxone in Vitro: Mechanical and Electrophysiological Actions

Ki Jun Kim,Haeng Cheol Lee,Ki Young Lee,Ji Young Kim,Sueng Teck Joo,Wyun Kon Park Korean Society of Critical Care Medicine 2002 Acute and Critical Care Vol.17 No.2

BACKGROUND: Naloxone,an opioidant agonist, has been s hown t o have a c ar di ovascular pressor effect in states of hemorrhagic and endotoxic shock.We determined the direct inotropic effect of naloxone using guinea pig right ventricular papillary muscles. METHODS: With institutional approval,isometric contractile force was measured in normal and 26mM K+ Tyrode's solution at various stimulation rates.Normal and slow action potentials (APs) were measured with conventional microelectrode technique.The effects of naloxone on sarcoplasmic recticulum function were evaluated by measuring rapid cooling contractures (RCCs)in normal Tyrode 's solution and rested-state (RS)contraction in low Na+ (25 mM)Tyrode's solution.Patch clamp study was performed to examine the direct effect on Ca2+ current in myocytes. RESULTS: Naloxone (50,100,200 micro M)caused dose-dependent depression of peak force and maximal rate of peak force (dF/dt-max)by 30,50 and 70%,respectively.Modest depression was shown in RS contraction in low Na+ Tyrode's solution.In 26 mM K+ Tyrode's solution,100 micro M naloxone markedly depressed late force development.100 micro M naloxone depressed RCCs by 20%. While 100 micro M naloxone did not alter amplitude or dV/dt-max in normal and slow APs at 0.25 Hz, AP duration was prolonged significantly.In patch clamp study,50 micro M naloxone depressed Ca2+ current by 50%. CONCLUSIONS: Naloxone depresses contractile force.Myocardial depressant effect partly seems to be caused by depressed Ca2+ influx through cardiac membrane.Rapid release of Ca2+ from the sarcoplasmic reticulum by depolarization and release by rapid cooling seems to be minimally affected.

RP-HPLC를 이용한 혈액에 포함된 펩타이드의 분리

이승기(Sueng Ki Lee),Yulia Polyakova,노경호(Kyung Ho Row) 한국생물공학회 2002 KSBB Journal Vol.17 No.3

학교체육시설물-철봉의 강도규정 및 이의 평가방법 개발에 관한 연구

강기원 ( Ki Weon Kang ),안병화 ( Byoung Hwa Ahn ),유승원 ( Sueng Won You ),도영민 ( Young Min Do ) 한국스포츠정책과학원(구 한국스포츠개발원) 2003 체육과학연구 Vol.14 No.1

학교체육시설물의 안전성 및 효율성을 향상시키기 위해서는 이의 구체적인 요건을 정하는 표준규격의 제정이 요구된다. 이러한 표준 규격은 품질규정, 형상규정 및 강도규정 등으로 세분화될 수 있으며 이 중 표준 규격의 핵심요소인 강도규정은 학교체육시설물이 보유하여야 하는 기준강도에 대한 내용을 포함하므로 이의 적합한 설정은 매우 중요하다. 또한 이와 같이 설정된 강도규정의 타당성 및 적합성을 검증하기 위해서는 강도규정에 대한 시험방법의 선정 역시 매우 중요하다. 그러나 철봉으로 대표되는 학교체육시설물은 대부분 운동장과 같은 야외에 설치·운영되고 또한 이의 운동형태가 매우 다양하므로 기존의 시험방법으로는 이에 대한 시험평가가 매우 어려운 실정이다. 따라서 본 논문에서는 대표적인 학교체육시설물인 야외용 철봉의 강도규정 및 이의 평가를 위한 시험방법을 제정하고 이들의 적합성 및 타당성 검증에 대한 연구를 수행하였다. The present study is aiming at developing the strength specification and evaluation methodology in horizontal bars intended for permanent installation for use at elementary, middle and high schools. For these purpose, the strength specification is, firstly, established through the structural analysis considering the environmental, service and loading conditions of horizontal bars. Additionally, an evaluation methodology is developed to identify the usefulness and conformity of the strength specification. And then this study ends with the tests for prototype of horizontal bars according to the strength specification and evaluation methodology through a portable universal testing machine, which is designed to be able to adjust the loading direction and operate outdoors.

아 역청탄 촤 산화 반응속도론에 관한 실험적 연구

강기태(Ki Tae Kang),송주헌(Ju Hun Song),이천성(Chuen Sueng Lee),장영준(Young June Chang),전충환(Chung Hwan Jeon) 한국에너지학회 2009 에너지공학 Vol.18 No.4

MZ세대의 운동참여 종목에 따른 과시적소비성향 및 상징적소비성향 비교연구: 무도, 골프, 보디빌딩 참여자 중심으로

전기제 ( Ki-jae Jeon ),성준영 ( Jun-young Sung ),신승아 ( Sueng-a Shin ) 대한무도학회 2022 대한무도학회지 Vol.24 No.1

이 연구의 목적은 최근 MZ세대들의 참여도가 지속적으로 증가하고 있는 골프와 보디빌딩 참여자와 무도에 참여하고 있는 MZ세대 참여자의 성향을 비교분석하고자 한다. 이를 통해 미래 환경 변화에 따른 무도 참여 활성화를 위한 기초적 자료를 제공하는데 있다. 연구의 대상은 무도, 골프, 보디빌딩 종목에 지속적으로 참여하고 있는 MZ세대 참여자를 대상으로 설정하였으며, 코로나19 바이러스 감염 우려를 대비해 Google온라인 설문조사로 설문을 진행하였다. 자료처리는 SPSS 23.0 통계프로그램을 활용하여, 빈도분석, 탐색적 요인분석과 신뢰도 분석, One-way ANOVA를 실시하였고, 사후검증은 Scheffe분석을 실시하였다. 연구결과, 첫째, 과시적소비성향 요인 중 타인인정지향, 종목의 상징성, 유행추구, 인기종목선호 요인에서 3종목 참여자 간의 차이가 있는 것으로 나타났으며, 골프 참여자의 과시적소비성향이 가장 높은 것으로 나타났다. 둘째, 상징적소비성 요인 중 자기계발 및 강화, 자아형성, 의사소통 및 교류 요인에서 3종목 참여자 간의 차이가 있는 것으로 나타났으며, 자기계발 및 강화는 보디빌딩 참여자, 자아형성은 무도 종목 참여자, 의사소통 및 교류는 골프 참여자가 가장 높은 것으로 나타났다. The purpose of this study was to compare and analyze the recent tendency of MZ generation to participate in golf, bodybuilding, and martial arts and the study was to provide basic data for revitalizing martial arts according to future environmental changes. The subjects of the study were MZ generation participants who continuously participated in martial arts, golf, and bodybuilding, and a Google online survey was conducted. For data processing, frequency analysis, exploratory factor analysis and reliability analysis, one-way ANOVA, and Scheffe analysis were performed using the SPSS 23.0. As a result of the study, first, propensity to others, symbolism of sports, pursuit of trends, and preference for popular sports factors of conspicuous consumption showed a significant differences according to each 3 sports events participants, and golf participants showed the significant highest the conspicuous consumption. Second, self-development and reinforcement, self-formation, communication factors of symbolic consumption showed a significant differences according to each 3 sports participants, and bodybuilding participants, martial arts participants, golf participants showed the significant highest the self-development and reinforcement, self-formation, and communication respectively.

호텔 종사원 직업선택 동기의 중요도-만족도(IPA)에 의한 추천의도 연구

김기철 ( Ki Cheul Kim ),고재승 ( Jae Sueng Ko ) 관광경영학회 2012 관광경영연구 Vol.50 No.-

The major variable and motivation in the selection of works for employees having engaged in the hotel is the priority variable that can have influence on customer satisfaction, so related businesses should perceive the importance for motivation of job selection of employees and it is necessary to find out variable of influence through actual method study. On the other hand, the study for the motivation of job selection of workers engaging in current hotel business and tourism industry is very restrictive. Therefore providing basic data is higher meaningful in an academic aspect not dealing with the subject related to this study until now, by finding out between importance and difference for motivation of job selection. As the result of this study, hypothesis I turns out to be a difference in the motivation of the job selection of the hotel workers, recommendation purpose and whole satisfaction of sex, the demographic trait, age, seniority, position, academic background, monthly income, company level and major. Hypothesis II shows the positive number in all measurement variable for importance and satisfaction of motivation for job selection of the hotel workers with the result analyzing IPA and there is low satisfaction in the job selection of hotel workers, while they are engaged in the hotel currently because the factor that they think importantly before entering into this hotel is changed after into. Hypothesis III shows the most important factor in the satisfaction and recommendation purpose is respect and self-realization in the satisfaction and working environment in the recommendation purpose as a result of analyzing influence relations for hotel workers, motivation and recommendation purpose of the job selection and whole satisfaction.

티타늄 가공의 공구 및 절삭 조건에 따른 가공 특성 고찰

홍기환(Ki-Hwan Hong),이승호(Seung-Ho Lee),김승우(Sueng-Woo Kim),조성훈(Sung-Hoon Cho),현용탁(Yong Tak Hyun),김형중(Hyung-Jung Kim) 대한기계학회 2013 대한기계학회 춘추학술대회 Vol.2013 No.12

高分子 界面活性劑에 관한 硏究 (第3報)

Nam Ki Dae(南基大),Jeong No Hee(鄭魯喜),No Sueng Ho(盧承鎬) 한국유화학회 1989 한국응용과학기술학회지 Vol.6 No.2

Allyl aliphatic carboxylates were synthesized by azotropic reaction with benzene between allyl alcohol and capric acid, lauric acid, myristic acid, palmitic acid or stearic acid respectively. allyl aliphatic carboxylates oligomers were prepared from polymerization giving allyl aliphatic carvboxylates in the presence of potassium persulfate in methanol, and the α-sulfonation of these five allyl aliphatic carboxylates oligomers were carried by direct addition of dry sulfur trioxide. Especially, molecular weights of fatty acid alylester oligomers and their sodium salts of α-sulfo fatty acid allylester oligomers were measured by boiling point method.

IEEE 802.15.4 MAC 계층의 성능 향상을 위한 분할 경합 접근 방식 (pp.436-440)

배성재(Sueng Jae Bae),기형주(Hyung Joo Ki),이태진(Tae-Jin Lee),정민영(Min Young Chung) 한국정보과학회 2008 정보과학회 컴퓨팅의 실제 논문지 Vol.14 No.4

본 논문은 IEEE 802.15.4 beacon-enabled 모드의 경합 접근 구간(CAP: Contention Access Period)에서 단말수의 증가에 따른 성능 저하를 개선하기 위해 분할경합 접근 방식(PCAM: Partitioned Contention Access Mechanism)을 제안한다. 분할 경합 접근 방식에서 PAN 코디네이터는 사용 가능한 전체 경합 접근 구간을 같은 크기의 두 개의 소구간으로 나눈다. 단말은 자신이 소속된 소구간에서만 전송을 위해 서로 경쟁한다. 이와 같은 방법으로 분할 경합 접근 방식은 경쟁하는 단말의 수를 반으로 줄여 전송 프레임의 충돌을 감소시키고 경쟁 시간을 반으로 줄여 단말의 전력 소모를 줄이는 특징을 가진다. 본 논문에서는 분할 경합 접근 방식과 기존 IEEE 802.15.4 표준의 접근 방식과의 성능을 비교하기 위해 시뮬레이션을 수행하였으며, 시뮬레이션 결과 정규화 수율 및 에너지 효율측면에서 분할 경합 접근 방식이 기존의 방식보다 좋은 성능을 가짐을 확인하였다. In IEEE 802.15.4 beacon-enabled mode, performance decreases as the number of devices competing in the contention access period (CAP) increases. In this letter, we propose partitioned contention access mechanism (PCAM) to compensate performance degradation. In PCAM, the PAN coordinator divides CAP into two subperiods and activity of devices is delimited in their assigned sub-periods. Since PCAM reduces the number of devices which compete at the same time by half, collision probability between transmitted frames can be reduced. In addition, devices can save their power consumption because PCAM shorten the duration that devices stay in active state into half. We perform simulations to compare the performance of PCAM with that of the IEEE 802.15.4 standard. From the result, PCAM yields better performance than IEEE 802.15.4 standard.

재해기상연구센터 모바일 기상관측차량시스템 소개

Kim, Ki-Hoon,Seon Jeong Kim,Sueng-Pil Jung,Sang-Ok Han 한국기상학회 2013 한국기상학회 학술대회 논문집 Vol.2013 No.4