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Cho, Han Jin,Lim, Do Young,Kwon, Gyoo Taik,Kim, Ji Hee,Huang, Zunnan,Song, Hyerim,Oh, Yoon Sin,Kang, Young-Hee,Lee, Ki Won,Dong, Zigang,Park, Jung Han Yoon MDPI 2016 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Vol.17 No.2
<P>Benzyl isothiocyanate (BITC) is a hydrolysis product of glucotropaeolin, a compound found in cruciferous vegetables, and has been shown to have anti-tumor properties. In the present study, we investigated whether BITC inhibits the development of prostate cancer in the transgenic adenocarcinoma mouse prostate (TRAMP) mice. Five-week old, male TRAMP mice and their nontransgenic littermates were gavage-fed with 0, 5, or 10 mg/kg of BITC every day for 19 weeks. The weight of the genitourinary tract increased markedly in TRAMP mice and this increase was suppressed significantly by BITC feeding. H and E staining of the dorsolateral lobes of the prostate demonstrated that well-differentiated carcinoma (WDC) was a predominant feature in the TRAMP mice. The number of lobes with WDC was reduced by BITC feeding while that of lobes with prostatic intraepithelial neoplasia was increased. BITC feeding reduced the number of cells expressing Ki67 (a proliferation marker), cyclin A, cyclin D1, and cyclin-dependent kinase (CDK)2 in the prostatic tissue. <I>In vitro</I> cell culture results revealed that BITC decreased DNA synthesis, as well as CDK2 and CDK4 activity in TRAMP-C2 mouse prostate cancer cells. These results indicate that inhibition of cell cycle progression contributes to the inhibition of prostate cancer development in TRAMP mice treated with BITC.</P>
경사진 입구를 갖는 급확대관내의 난류유동과 열전달특성에 관한 실험적 연구
권기린,한진규 濟州大學校 工科大學 産業技術硏究所 1994 産業技術硏究報告 Vol.5 No.-
Experiments were carried out for the turbulent flow and heat transfer downstream of an 10^(2) -inclined concentric expansion in a circular pipe with a constant wall heat flux. The uniform heat flux condition was imposed to the downstream of an inclined expansion by using an electrically heated pipe and the folw upstream of the expansion was unheated and fully developed. Runs were made with small diameter to large diameter ratio of 0.33 and over the Reynolds numbers range of 60,000, 90.000 and 120,000 (based on upstream diameter). Experiments were tested with air as working fluid. The results ovtained are summarized as follows; 1) Fully development region showed from x/d=22 to downstream in an 10^(2) - inclined concentric expansion turbulent flow through the test tube. 2) Friction factors of the test tube showed a maximum value at x/d=15. 3) For all Reynolds number, the wall temperature showed a curve of parabolic variation at 16<x/d<48, and the bulk temperature showed a linear distribution of increse at 9<x/d<48. 4) The location of the maximum Nu/NuDB showed at the point of 16 step-heights for Re= 60,000, 90,000 and 120,000 of an 10^(2) - inclined concentric expansion.
Squash 운동이 성인 여성의 호흡순환기능에 미치는 영향
권해주,김태운,고기준,한재웅,이재규 부산대학교 체육과학연구소 2000 體育科學硏究所 論文集 Vol.16 No.-
The purpose of this research was to change the effects of Squash exercise on cardiopulmonary functions of females. The subject group was made up of 10 females (first start to Squash exercise). After a pretest, the subjects were given an 12-weeks Squash exercise program. Then the subjects were given a posttest and cardiopulmonary functions after 12-weeks of the program. The program schedule was made up of 3days per week, 60minutes per day. The significance level was α=0.05. The following results were statistical data of difference between pre and post-test. 1.HRmax was significantly increased. 2.RFmax was significantly increased. 3.VO2 max was significantly increased.
다운증후근 아동과 청소년의 슬관절 등속성 근력 특성 비교
한동기,김권일 한국특수체육학회 2003 한국특수체육학회지 Vol.11 No.1
This study was to provide fundamental information of muscle strength training, gait, and gross motor movement through comparing and analyzing low limb isokinetic torque of children and adolescents with Down syndrome. The subjects were 8 children with Down syndrome and 8 adolescents with Down syndrome. The peak torque, average power, and total work were measured with Cybex 770 at the speed 0f 60˚/sec and 180˚/sec. The data were analyzed by SPSS. The conclusions were drawn as follows; 1. The peak torque was decreased as angular velocity increasing. 2. Muscle strength was unequal between left and right knee joint. 3. Adolescents with Down syndrome were higher that children in the peak torque, average power, total work, and flexor/extensor ratio. Therefore, children and adolescents with Down syndrome had normal characteristics related with isokinetic strength. However, there are lots of possibilities of injury during activities because of the imbalance between left and right leg and low flexor/extensor ratio.
산업장 근로자를 대상으로 실시한 한방 건강검진의 만족도
한현정,정재열,권소희,손용선,장두섭,이기남 한국산업위생학회 2003 한국산업보건학회지 Vol.13 No.2
The examinees who received oriental and western health examination both and submitted questionnaire were 257 workers in workplace for 1 month during health examination for industrial workers. The research was to compare the satisfaction of oriental and western health examination by the questionnaire. The data that were collected by health examination were analyzed into frequencies, ANOVA, T-test with use of SPSS 10.0 program by the research purposes. The results were as follows: 1. Health examination in satisfaction comparison by the general characteristics of subject was significant in oriental health examination for the subjects who had 9-10 working hours(P〈0.05). 2. The workers who had high confidence in result of health examination, affirmative thinking for requirement of health examination, arbitrary decision for receiving the health examination, had high satisfaction in oriental and western health examination both, It was statistically significant difference. 3. For the difference in subjective health condition's recognition, the subject who answered " Healthy" had high satisfaction in western health examination, and it was statistically in western health examination, and it was statistically significant The subject who answered "Healthy" for the early detection of disease had high satisfaction in western health examination, The subject who answered skeptical for the early detection of disease had high satisfaction. in oriental health examination and it was statistically significant. 4. The respondent who said "Yes" for the question, whether you know about oriental health examination or not before receiving oriental health examinatgion had relatively high satisfaction For the question about including of oriental health examination continuously in the coming future, the subject who replied affirmative answer had high satisfaction in average, and it was significant difference(P〈0.05). 5. For the question that will be needed in the item of oriental health examination, the highest item was the requirement of specific oriental health examination for various diseases, followed by the requirement of medical specialist for individual need of medical examination by the item, and the prescription of herbal medicine, the medical examination of cancer, the interview for folk remedies, the parallel treatment for acupuncture cupping, etc, the medical examination for adult disease, the requirement of room for medical examination etc.
한동기,김권일 한국특수체육학회 2003 한국특수체육학회지 Vol.11 No.2
The purpose of this study was to analyze special teachers' recognition toward the goals of physical education in the elementary school for the students with mental retardation. The subjects of this study were 237 teachers in the elementary school for the students with mental retardation, located in Seoul, Kyong-Ki, and In-Chon. The results of this study were as follows: 1. The male teacher group showed a higher than female teacher group recognition level on the goals except for the goals of psychic equilibrium and spatial orientation. 2. There were differences in the goals of physiological efficiency, object manipulation, communication, group interaction and cultural involvement among the groups by career. 3. Teachers of lower grade(1~3) have a higher level of recognition than level of upper grade(4~6) on the goal of 6 areas except the goal of spatial orientation. 4. There were no differences in recognition level of the goals of the physical education between the teachers with physical education class responsible and without.