建築設備工事의 施工性 向上에 관한 硏究 : 설비전담부서의 설치 필요성을 중심으로

조형근,구자두 호남대학교 1998 호남대학교 학술논문집 Vol.19 No.2

Recently construction has become large in scale, high, complex, diverse, and professional, and its consumers demand improved quality in living environments, design and construction in building services must improve in precision. However, quite often people who carry out building services works do not prepare design documents, and poor construction with defects occur in construction site many times. To address this matter, I have conducted a questionnaire survey with students in Honam Construction Engineering Education Center and officers and students in Army Engineering School for this study. The survey is about causes of poor construction that are requirement of employing specialist of building services, setup of a service department related with the matter. After the collected guestionaire data divided according to the kinds of major business and qualification educational background work experiences, the requirements of setup of a department exclusively responsible for building services and employment of relative specialists are analyzed. Base on the above results, to suggest basic methodology of constructability improvement of building services works.

建築設備工事의 施工性 向上에 관한 硏究(Ⅱ) : Focued on the Changes and Prior Coodinate 설계변경 또는 공사변경 및 이에 따른 사전협의를 중심으로

具滋斗,趙炯權 호남대학교 산업기술연구소 1999 산업기술연구논문집 Vol.7 No.-

건축물의 규모가 대형화, 고층화, 복잡화됨에 따라 건축설비공사의 중요성은 점차 증대되고 있다. 이에 본 연구에서는 건축설비공사와 관련된 설계변경 또는 공사변경 및 이에 대한 사전협의에 관한 설문조사를 실시하여 주력사업별과 자격 및 경력별로의 분석을 통해 건축설비공사의 시공성 향상을 증진하는 기초자료를 제공하고자 한다. Recently construction has become large in scale, high, complex, diverse, and professional, design and construction in building services must improve in precision. However, quite often people who carry out building services works do not prepare design documents, and poor construction with defects occur in construction site many times. To address this matter, I have conducted a questionnaire survey for this study. After the collected guestionaire data divided according to the kinds of major business and qualification educational background work experiences, the changes and prior coodinate in the design and construction of building services works are analyzed. Base on the above results, to suggest basic methodology of constructability improvement of building services work.

카드뮴투여가 흰쥐 고환의 조직변화와 단백질변화에 미치는 영향

최송표,김수일,조근자,양은진,김선,박경란,이영호,김원식 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.2

This study was done to investigate histochemical and protein changes in the rat testis I WAT and 3 WAT with 4 mg/kg of cadmium, IP, single injection. A control group and 2 experimental groups were studied. Testes were processed routinely for H&E stain and agarose gel electrophoresis. The results were as follows ; 1. In the histochemical studies, death of all the spermatogenic cells and Sertoli cells in the seminiferous tubules, and decreased ground substance, decreased fibroblasts and interstitial cells and increased inflammatory cells in the interstitial tissues were found in the cadmium treated groups, and the degree of necrotic changes was more severe in the 3 WAT group. 2. In the biochemical studies, two kinds of proteins, 25 kDa and 45 kDa, were disappeared and one kind of protein, 100 kDa, was decreased after Cd treatment. 25 kDa and 45 kDa proteins were suggested as actin which consist the spermatogenic cells, but what's the protein 100 kDa is unclear. According to the above results, it is considered that there would be irreversible changes in seminiferous convoluted tubules and also in the interstitial tissues after cadmium treatment, and detecting amino acid sequences of these proteins would help understanding the mechanism of necrosis in the testis tissue after cadmium administration.

5-FU로 백서 가슴샘에서 유도된 세포고사의 Comet Assay에 의한 분석

김수원,한승로,정옥,조근자,김선,김원식 충남대학교 의과대학 지역사회의학연구소 2001 충남의대잡지 Vol.28 No.1

Thymus is a lymphoid organ forming T-cells from hematogenous stem cells. Apoptosis of thymocytes in the cortex of thymus is so rapid that cannot find easily with routine histological techniques. In this experiment, Comet assay and SDS-PAGE were used to detect apoptotic changes and protein changes after 5-fluorouracil(5-FU) treatment in the thymus of the rat. The results were as follows. 1. The number of thymocytes in the cortex was markedly decreased, and many apoptotic cells with various size and shapes were found on DAT 5 in 5-FU treated group. 2. On DAT 5, new nodules with germinal centers began to appear in the peripheral cortex, and in the germinal center, there was many apoptotic bodies of various size and shapes. 3. In SDS-PAGE, a protein with molecular weight of 123kDa was increased on DAT 5 which was considered as integrins subfamily.

유방암종에서 p53, cyclin D1 및 cathersin D 단백발현의 의의

문경래,김환정,이미자,기근홍,서재홍,양정원,조현진 조선대학교 2001 The Medical Journal of Chosun University Vol.26 No.2

Background and Objectives: Breast carcinoma is a heterogenous disease. The prognosis of this carcinoma correlates with various prognostic factors. The aim of this study was to assess the prognostic significance of expression of p53, cyclin Dl and cathepsin D protiens in association with various prognostic factors in invasive breast carcinoma. Materials and Methods: The relationship is presented between expression of p53, cyclin D1 and cathepsin D by immunohistochemistry and various established prognostic factors such as tumor size, histologic grade, lymph node status and extensive intraductal component in 55 cases of invasive breast carcinoma. Results: No significant correlations were observed between expression of p53, cyclin Dl and cathepsin D and tumor size. The expression of p53 correlated with high histologic grade. The expression of p53 and cyclin Dl correlated with lymph node metastasis. Conclusion: These results indicate that expression of p53 and cyclin Dl in invasive ductal carcinoma may be an important prognostic factor, closely related to the high histologic grade and lymph node metastasis.

Pseudomonas sp. EL-G527에 의한 환경친화성 생물계면활성제의 생산최적조건

차미선,임은경,이근희,조순자,손흥주,이상준 한국환경과학회 2002 한국환경과학회지 Vol.11 No.3

A biosurfactant-producing microorganism was isolated from activated sludge by enrichment culture when grown on a minimal salt medium containing n-hexadecane as a sole carbon source. This microorganism was identified as Pseudomonas sp. and it was named Pseudomonas sp. EL-G527. It's optimal culture condition is 2% n-hexadecane, 0.2% NH_4NO_3, 0.3% KH_2PO_4, 0.3% K_2HPO_4, 0.02% MgSO_4·7H_2O, 0.0025% CaCl_2·6H_2O, 0.0015% FeSO_4·7H_2O in 1ℓ distilled water and initial pH 7.0. Cultivation was initiated with a 2% inoculum obtained from starter cultures grown in 30 ㎖ of the same medium in 250 ㎖ flask. They were cultivated at 30 ℃ in reciprocal shaking incubator and the highest biosurfactant production was observed after 4 days.

지문과 정신분열증

우숙희,정국동,최송표,조근자,양은진,김수일,박경란,이영호,김원식 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

Fingerprint patterns of 333 schizophreniacs who met with the diagnostic criterias of International Pilot Study of Schizophrenia except items associated with chronicity in exclusion criteria were studied, and the following results were obtained. 1. The frequency distribution of the fingerprint patterns in the 333 schizophreniacs was ulnar loop, whorl, twinned loop, arch, radial loop in order in both control and schizophrenia groups. 2. Finger ridge counts of both sexes were decreased significantly in schizophrenia group. 3. Dissociation of fingerprint pattern in the schizophrenia group was 51.1%, which was far greater than 6.25% of control group. Number of dissociation was greatest in the thumb, followed by index, middle, ring, and little finger in order. According to the above results, it is considered that both the number of finger ridges and degree of dissociation of fingerprint patterns were closely related with schizophrenia. Analysis of fingerprints and palmprints with the aid of chromosomal analysis would contribute the early diagnosis and prevention of schizophrenia.

Podocyte-specific Expression of C1q/TNF-α Related Protein 1 in Mice

Keun-Ja Cho(조근자),Young Yang(양영),Young Ho Lee(이영호),Sooil Kim(김수일) 대한체질인류학회 2013 해부·생물인류학 (Anat Biol Anthropol) Vol.26 No.4

C1q/TNF-α Related Protein 1 (CTRP1)은 adiponectin의 파라로그로서 C1q/TNF-α?Related Protein 계열의 새로운 물질이다. CTRP1은 콩팥에서 발현되지만 콩팥에서의 국소발현과 기능에 대해서는 알려져 있지 않다. 본 연구에서는 CTRP1의 콩팥에서 발현과 기능을 알아보고자 하였다. C57/BL6쥐와 FGS/Nga 생쥐의 콩팥에서 CTRP1에 대한 면역조직화학염색과 PAS 염색을 하였다. Podocin에 대한 in situ hybridization도 생쥐 콩팥에서 시행하였다. CTRP1 양성세포가 콩팥의 토리에서 발견되었으며, 이들 세포가 발세포임을 확인하였다. CTRP1 양성세포 수와 면역강도는 진행형 단백뇨와 국소토리굳음증을 나타내는 FGS/Nga 생쥐 토리에서 감소하였다. CTRP1은 생쥐 콩팥의 발세포에서 발현되는 단백질이며 콩팥에서 토리 여과와 관련된 역할을 할 것으로 본다. C1q/TNF-α Related Protein 1 (CTRP1), an adiponectin paralog, is a novel member of the C1q-TNF Related Protein family. CTRP1 is expressed in the kidney, although its localization and role in the kidney have not been studied. This study examined CTRP1 expression and function in the kidney. CTRP1 immunohistochemistry and PAS staining of the kidneys of C57/BL6 and FGS/Nga mice were performed. In situ hybridization for podocin in the kidney was also performed. CTRP1 immunoreactivity was found only in the glomeruli of the kidney. The CTRP1-immunoreactive cells in the glomeruli were identified as podocytes. The number of CTPR1-immunoreactive cells and the intensity of CTRP1 immunoreactivity were lower in the glomeruli of FGS/Nga mice, which develop progressive proteinuria and focal glomerulosclerosis. CTRP1 is a novel protein expressed in podocytes of the mouse kidney and may have a role in podocytes related to glomerular filtration in the kidney.

초등학생의 공격성 양상을 평가하기 위한 신체적 지표로서 둘째-넷째손가락 길이비 (2D : 4D)의 활용

조근자(Keun-Ja Cho),김수일(Sooil Kim) 대한체질인류학회 2017 해부·생물인류학 (Anat Biol Anthropol) Vol.30 No.4

본 연구는 초등학생의 둘째-넷째손가락 길이비에 따른 공격성의 차이를 분석함으로써 청소년범죄, 폭력 등을 사전에 예방할 수 있는 기초적인 자료를 제공하고자 한다. 둘째-넷째손가락 길이는 손가락 복사본에서 손바닥쪽 몸쪽 주름 중간지점부터 손가락 끝까지의 최단거리를 디지털 캘리퍼스를 이용하여 0.01 mm까지 측정하였다. 공격성은 30문항으로 된 질문지를 사용하여 자가응답식으로 기입하였다. 대상자는 초등학교 3학년부터 6학년까지 187명 (남자 98명, 여자 89명)이었으며, 자료수집은 2016년 9월 19일부터 10월 7일까지 실시하였다. 자료 분석은 SPSS win 21.0을 이용하였으며, 분석방법은 교차분석, 독립표본 t-검정을 사용하였다. 연구 결과 둘째-넷째손가락 길이비는 남자가 유의하게 낮았고 (p=.025), 공격성은 남자가 유의하게 높은 것으로 나타났다 (p=.020). 특히, 둘째-넷째손가락 길이비에 따른 공격성은 남학생의 왼손가락 길이비에서만 0.900이하인 집단이 1.000 이상인 집단보다 통계적으로 유의하게 높은 것으로 나타났다 (p=.002). 따라서 둘째-넷째손가락 길이비, 특히 왼손가락 길이비는 남자 초등학생에서 공격성을 평가하는 신체적 지표 중 하나로 활용하는 것을 고려해 볼 수 있을 것이다. The aim of this study is to provide basic data to prevent adolescent crime or violence by analyzing aggression according to second digit to fourth digit ratio (2D : 4D). Index and ring finger length on both hands by photocopy was measured using Callipers from ventral proximal crease to finger tip. This study was done on 187 elementary school students (98 males, 89 females). Data were collected by measuring index and ring finger length on both hands by photocopy and by completing self-reported questionnaire. The data were analyzed using SPSS win 21.0. This study showed that the 2D : 4D of males was significantly lower than female, and the aggression score of males was significantly higher than female. Especially, there was significantly differences between 0.900 or less than 0.900 digit ratio group and 1.000 or more than 1.000 digit ratio group only left hand of males. The results of this study suggest that left digit ratio of males in elementary school students are able to be used as one of physical markers to evaluate aggression.

손잡이에 따른 지문의 특성

조근자(Keun-Ja Cho),김수일(Soo-Il Kim) 대한체질인류학회 2010 해부·생물인류학 (Anat Biol Anthropol) Vol.23 No.1

왼손잡이는 유전성을 가지고 있으며 오른손잡이와 대뇌조직화의 양상이 서로 다르며 인체의 비대칭성은 발생초기에 어느 한쪽의 세포분열이 더 빠르다는 것을 암시한다. 지문 역시 유전성향이 있고 개인마다 다르며 선천적으로 결정되어 일생동안 변하지 않는다. 따라서 본 연구에서는 한국인을 대상으로 손잡이 유형을 분류하고, 손잡이 유형에 따른 지문의 특징을 분석함으로써 지문이 선천적으로 우세한 손에 따라 유전적으로 차이가 있는지 확인해 보고자 하였다. 연구대상은 대전ㆍ충남지역의 대학생 1,063명을 대상으로 손잡이 평가도구를 이용하여 평가한 후 지문채취에 동의한 199명(왼손잡이: 55명, 오른손잡이: 144명)이었으며 수집된 자료는 SPSS 15.0을 이용하여 신뢰도분석, 교차분석, X² test, independent t-test, paired t-test로 분석하였다. 손잡이 유형에 따른 지문의 성별 빈도는, 남자와 여자 모두 왼손잡이가 오른손잡이보다 활형이 많고(남자 4.7%, 여자 12.3%) 소용돌이형은 적었으며(남자 31.3%, 여자 38.2%), 왼손잡이와 오른손잡이 모두 성별에 따라 지문분포순서에 차이가 있는 것으로 나타났다. 또한 왼손과 오른손 모두 왼손잡이가 오른손잡이보다 활형과 자쪽고리형이 많고 노쪽고리형과 소용돌이형은 적었다. 왼손과 오른손의 손잡이에 따른 손가락별 지문유형은 왼손에서 가운데손가락(p<0.05), 반지손가락(p<0.05), 새끼손가락(p<0.01)이 손잡이 유형에 따라 유의하게 다른 것으로 나타났다. 지문의 능선 수는 왼손잡이가 왼손 집게손가락(10.2)과 가운데손가락(11.4)에서, 그리고 오른손 가운데손가락(11.0)과 반지손가락(14.0)에서 오른손잡이보다 유의하게 적은 것으로 나타났다(p<0.05). 삼교차점수는 양손 모두 왼손잡이가 가운데손가락, 반지손가락, 새끼손가락에서 유의하게 오른손잡이보다 적은 것으로 나타났으며, 총삼교차점수도 왼손잡이(12.6)가 오른손잡이(14.1)보다 유의하게 적었다(p<0.05). 지문의 형태는 손잡이의 유형에 따라 지문유형 분포, 피부능선수, 삼교차점에서 차이가 있는 것으로 나타났으며, 특히 왼손잡이에서 활형이 두드러지게 나타나고, 왼손에서 왼손잡이와 오른손잡이의 지문차이가 현저한 것으로 나타났다. 따라서 지문은 선천적으로 우세한 손잡이의 발달에 따라 유전성을 반영하는 것으로 사료된다. Left handedness is known to be related with inheritance and is different from right handedness in brain development and various aspects of perceptive and cognitive performance. Fingerprints are also related with inheritance and do not change for the whole life. In addition, individuals have different fingerprints. The aim of the present study was to identify genetic correlation between fingerprints and handedness by examining how different fingerprints are between left handers and right handers. The study group to imprint fingerprints was composed of 55 left handers and 144 right handers of 1063 college students. The reliability of handedness assessment tool was Cronbach’s α=0.948. The imprinted fingerprints were classified by fingerprint type (arch, radial loop, ulnar loop, whorl). Finger ridges and triradii in fingerprints were also counted. We performed frequency analysis, reliability analysis, cross-tabs analysis, X2 test, independent t-test, paired ttest by SPSS win 15.0 for the data. The left handed males and females exhibited more arch types than the right handers and less whorl types than the right handers. The left handers in both hands exhibited more arch and ulnar loop types than the right handers and less whorl and radial loop types than the right handers. In the left hand, the 3rd (p<0.05), 4th (p<0.05), and 5th (p<0.01) fingerprints of the left handers were different from those of the right handers. The finger ridge counts of left handers were significantly less than those of the right handers in the 2nd and 3rd fingers of the left hand, and in the 3rd and 4th fingers in the right hand. The triradii counts of left handers were significantly less than those of right handers (p<0.05) in the 3rd, 4th, and 5th finger of the left and right hand. Total triradii counts of left handers were also significantly less than those of right handers (p<0.05). These results demonstrate that fingerprint type, finger ridge and triradius counts of the left handers are different from those of the right handers, and fingerprints may reflect genetic tendency for handedness.