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Meteorological mechanisms in association with long-range transport of Asian dust in April 2001 have been investigated using weather maps, satellite images, TOMS and surface PM_10 data, backward trajectories, plus modeling output results (geopotential heights, horizontal wind vectors, potential temperatures, and streamlines). The results indicated that long-range transport of Asian dust to the west coast of North America was associated with strong westerlies between the Aleutian low and the Pacific high acting as a conveyor belt. Accelerating westerly flows due to cyclogenesis at the source regions over East Asia transported pollution from the continent to the central Pacific. When the system reached the Aleutian Islands, the intensity of troughs and the westerlies were amplified in the North Pacific. Thereafter the winds between the Aleutian Islands and the Pacific Ocean were more intensified from the air flow transport of the conveyor belt. Consequently, the strong wind in the conveyor belt enhanced the dust transport from the Pacific Ocean to the west coast of North America. This was evidenced by PM_10 concentration (maximum of about 100㎍m³) observed in California. Further evidence of the dust transport was found through the observation of satellite images, the distribution of TOMS aerosol index, and the analyses of streamlines and backward trajectories.
[Purpose] This study aimed to investigate the effects of treadmill exercise on body weight, blood biochemistry, and autophagy. [Methods] Triglyceride, total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, insulin, and glucose levels were measured, the Homeostatic Model Assessment of Insulin Resistance (HOMA-IR) score was calculated, and the soleus muscle was analyzed for autophagy- related factors (Beclin-1, p62, LC3, Lamp- 2) in rats with obesity induced by a high-fat diet. Eight-week-old Sprague Dawley rats were fed a high-fat diet for 35 weeks and then subjected to 10 weeks of treadmill exercise. The experimental group was divided into a Normal Diet-Sedentary (ND-SED, n=8) group, an (High-Fat Diet-Sedentary (HF-SED, n=8) group, and an High-Fat Diet + Treadmill Exercise (HF-TE, n=8) group. The intensity of treadmill exercise was set as 8 m/min for 5 min, 11 m/min for 5 min, 15 m/min for 20 min, and 11 m/min for the last 5 minutes. A glucose tolerance test was performed at the 2nd and 8th week of exercise by sampling of tail blood. [Results] With endurance exercise, the HFTE group showed a significant decrease in body weight, with improved blood biochemical indices and HOMA-IR scores, in comparison with the HF-SED group. However, there was no significant difference in Beclin-1, p62, LC3, and Lamp-2 proteins as measured by autophagic flux in the soleus muscle. [Conclusion] Treadmill exercise induced improvements in body weight, body fat, and biochemical indicators of obesity and Type 2 diabetes, but had no effect on autophagy in soleus muscle.
on the Effects of Biomedicinal Agents on Serum Concentration of Ca2+, P andALP Activity in Osteoporosis-Induced RatsSang-keun Kim, Myung-hun Lee1 and Man-hee Rhee2College of Veterinary Medicine, Chungnam National University, 220 Gungdong, Yusong-Gu, Daejeon 305-764, Korea1National Veterinary Research and Quarantine Service, Anyang 430-824, Korea2College of Veterinary Medicine, Kyungpook National University, Daegu 702-701, KoreaReceived April 3, 2003 / Accepted July 9, 2003J. Vet. Sci. (2003), 4(2), 151-154JOURNAL OFVeterinaryScience*Corresponding author: Sang-keun Kim Dept. of Vet. Med., Chungnam National University, Daejeon 305764, Korea Tel: +82-42-821-6754, Fax: +82-42-821-6754 E.-mail: email@example.com
Park Young-Keun has been evaluated as the first rate labour poet in Korea. He published Kim MiSoon Jeon which had unique elements such as epic poetry, Pansori, and Kim Jiha`s Damsi. In this long poem, the poet represents a female labourer who is innocent because of her lack of identity. She has strong desire for fashion, money and sex which are superficial elements of capitalistic society. She comes to be the victim of power that would cooperate with capital. Kwon Doga seduces her to play the role of fraktsiya. She dares to approach the leader of labor union, Walsun. She pretends to sacrifice for the union, by which she gets the trust of Walsun. Then, she steals the information of the union, which lets Walsun be prisoned. The poet tries to describe the situation objectively by using multi-viewpoints of Pansori. With this literary technique, he overcomes the literal weakness of dichotomy which has usually appeared in Labor poems. Park Young-Keun represents the characters of power, capital and laborers objectively by keeping distance, so that he can criticize even the members of labor union lacking in their own identities and strong will for reformation of society. However, the poet shows the reversal of MiSoon by having Deleuze`s good meeting which permits her spiritual transformation. She, in her fantasy or dream, meets her mother and Walsun, which leads her into repentance for her previous role as fraktsiya. From this motive, she rejects Kwondoga`s offer to play the immoral role. By discovering her transcendent change, the agent of power decides to kill her who knows too much about the conspiracy of power and capital. Experiencing the painful suffering given by the power, she would not surrender to it. Rather, she can get the complete freedom as a real labourer which can be evaluated as complete ``JeongDong`` of Deleuze.
Objectives: Genetic polymorphisms of Monoamine oxidase A (MAO-A) have been investigated in affective disorders. The results were controversial and even contradictory. In order to evaluate the genetic polymorphisms of MAO-A in Korean major depressive disorder, I investigated the genotype distribution and allele frequencies of MAO-A in the patients group, and compared them with those of healthy control group. Methods: Using polymerase chain reaction and electrophoresis, MAO-A genotypes were identified in 42 major depressive disorders and 100 healthy controls. Results: When genotypes of MAO-A were classified as g/g, g/t, t/t, there were no statistical differences in the genotype distribution and allele frequencies between two groups. Conclusion: These results suggest that genetic polymorphisms of MAO-A seem to be unrelated to pathogenesis of major depressive disorder.
이 논문은 2011년 10월 26일 서울시장 보궐선거에서 나타난 안철수 열풍이 여야 후보자들의 인지도에 어떠한 영향을 미쳤는지를 측정할 수 있는 계량적 방법을 제시하고 그 영향력을 측정한다. 곧 언론에 보도된 주요 인물들의 기사 건수를 자료로 삼아 아리마(ARIMA)분석기법을 사용하여 후보들을 나는 시계열로, 다른 주요 인물들을 드는 시계열로 삼아 여러 변수 아리마 모형을 만들어 그 영향력을 분석하였다. 그 결과 안철수의 영향력은 박근혜 영향력의 한 배 반 이상으로 나타났다. 박근혜는 나경원 후보의 인지도 증가에만 영향을 미치지만, 안철수는 박원순 후보에게는 인지도 증가뿐만아니라 나경원 후보의 인지도 감소에도 영향을 미치고 있다는 것을 추론할 수 있었다. 이 논문은 후보자 중심의 연구에서 벗어나 제 3의 인물이 선거 과정에 미친 영향력을 연구하는 시발점이 되었다는 점에서 정치 연구의 지평을 넓히고 있고, 제3의 인물이 선거판에 미친 영향을 단지 막연한 추측에서 벗어나 과학적으로 측정하고 분석할 수 있는 방법을 제시하였다는 점에 그 의의가 있다. This paper attempts to express, in the quantitative terms, the influence of Chul-Soo Ahn and Keun-Hye Park on the Mayoral Election of Seoul to fill a vacancy. We test some quantitative methods to measure the influence of the third influential person on the voter`s cognition of the candidates, and discuss the advantages of the Multivariate ARIMA(MARIMA) modeling techniques to excavate the influence. Based on the relations among the empirical data, MARIMA models were made, and compared Chul Soo Ahn`s influence with Keun-Hye Park`s influence. From the models, we infer that Ahn`s influence might be more than one-and-a-half times of Park`s in the election. This paper contributes to developing a quantitative method to find out the third person`s influence on the candidates, and stimulates the study of the third person`s influence in the electoral process.
Luteolysis is a cyclical regression of the corpus luteum in many non-primate mammalian species. Prostaglandin F2α (PGF2α) from the uterus and ovary induces functional and structural luteolysis in bovine. The action of PGF2α is mediated by PGF2α receptor located on the luteal steroidogenic and endothelial cell membranes. PGF2α plays an important role in regulating nitric oxide production in endothelial cells of the bovine corpus luteum. Nitric oxide production and nitric oxide synthase activity are stimulated and induced by PGF2α in luteal endothelial cells. Moreover, the reactive oxygen species inhibits progesterone secretion in bovine luteal cells and induces apoptosis. Thus, the interaction between PGF2α and reactive oxygen species provides important aspects in physiology of the corpus luteum forfunctional and structural luteolysis.
Fifty patients with the advanced non-small cell lung cancer, who had no previous treatment, were treated with a combination chemotherapy regimen consisting of cisplatin (20mg/㎡ i.v. day 1-5), etoposide (100 mg/㎡ i.v. day 2-4), and vinblastine (6 mg/㎡ i.v, day 1) every 3 weeks. Among the 50 patients entered into this study 45 patients were evaluable for response. Objective responses were achieved in 49 % (22/45) of patients (2 CRs, 20 PRs). In 23 patients with limited disease, the response rate was 61% (14/23) with no complete response, higher than that, but not statistically significant, in the extensive disease patients (36% with 2 CRs). The overall median survival of the patients was 42.6 weeks and the responding patients survived longer than non-responders (median survival; 51.5 weeks vs. 37.4 weeks, p$lt;0.05). Toxicity with this regimen was acceptable; myelosup- pression was the major toxic effect and was severe in only 11% of the patients with one treatment- related death from sepsis associated with granulocytopenia. The gastrointestinal side effects and alopecia were rather universal and the peripheral neuropathy (20%) and azotemia (9%) were not uncommon, but manageable in general.