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An Improved Pseudorandom Sequence Generator and its Application to Image Encryption
Keshav Sinha,Partha Paul,Amritanjali 한국인터넷정보학회 2022 KSII Transactions on Internet and Information Syst Vol.16 No.4
This paper proposes an improved Pseudorandom Sequence Generator (PRSG) based on the concept of modular arithmetic systems with non-integral numbers. The generated random sequence use in various cryptographic applications due to its unpredictability. Here the mathematical model is designed to solve the problem of the non-uniform distribution of the sequences. In addition, PRSG has passed the standard statistical and empirical tests, which shows that the proposed generator has good statistical characteristics. Finally, image encryption has been performed based on the sort-index method and diffusion processing to obtain the encrypted image. After a thorough evaluation of encryption performance, there has been no direct association between the original and encrypted images. The results show that the proposed PRSG has good statistical characteristics and security performance in cryptographic applications.
Carotid cavernous fistula: Redefining the angioarchitecture
Keshav Mishra,Vivek Kumar,Vinay,Ashok Gandhi,Trilochan Srivastava 대한뇌혈관외과학회 2022 Journal of Cerebrovascular and Endovascular Neuros Vol.24 No.4
Objective: Numerous classification schemes have been used for carotid cavernous fistula (CCF), each describing some aspect of the disease process but none of them provides a complete description of the fistula including its clinical features, natural history, arterial and venous architecture. Methods: Retrospective clinical and radiological review was done for all the patients diagnosed with CCF and treated at our institute. The CCF were classified according to the proposed API-ACE classification along with Barrow and Thomas classification. Results: Overall 28 patients (M=21, F=7) were diagnosed and treated during the 6-year period. 89.2% of CCF developed following an episode of head injury. Orbital symptoms were the most common presenting complaints. Barrows type A was the most predominant subtype (n=24) and most of the patients (n=23) demonstrated decreased ipsilateral carotid filling. Combined anterior and posterior drainage pattern was the most common drainage pattern and anterior drainage was more commonly observed than posterior drainage. Conclusions: API-ACE classification helps to better understand and classify the angioarchitecture of CCF which could
Keshav Kumar Nepal,오태진,Bimala Subba,유진철,송재경 한국분자세포생물학회 2009 Molecules and cells Vol.27 No.1
Amino acid homology analysis predicted that rbmD, a putative glycosyltransferase from Streptomyces ribosidificus ATCC 21294, has the highest homology with neoD in neomycin biosynthesis. S. fradiae BS1, in which the production of neomycin was abolished, was generated by disruption of the neoD gene in the neomycin producer S. fradiae. The restoration of neomycin by self complementation suggested that there was no polar effect in the mutant. In addition, S. fradiae BS6 was created with complementation by rbmD in S. fradiae BS1, and secondary metabolite analysis by ESI/MS, LC/MS and MS/MS showed the restoration of neomycin production in S. fradiae BS6. These gene inactivation and complementation studies suggested that, like neoD, rbmD functions as a 2-N-acetlyglucosaminyltransferase and demonstrated the potential for the generation of novel aminoglycoside antibiotics using glycosyltransferases in vivo.
Randomized Block Size (RBS) Model for Secure Data Storage in Distributed Server
( Keshav Sinha ),( Partha Paul ),( Amritanjali ) 한국인터넷정보학회 2021 KSII Transactions on Internet and Information Syst Vol.15 No.12
Today distributed data storage service are being widely used. However lack of proper means of security makes the user data vulnerable. In this work, we propose a Randomized Block Size (RBS) model for secure data storage in distributed environments. The model work with multifold block sizes encrypted with the Chinese Remainder Theorem-based RSA (C-RSA) technique for end-to-end security of multimedia data. The proposed RBS model has a key generation phase (KGP) for constructing asymmetric keys, and a rand generation phase (RGP) for applying optimal asymmetric encryption padding (OAEP) to the original message. The experimental results obtained with text and image files show that the post encryption file size is not much affected, and data is efficiently encrypted while storing at the distributed storage server (DSS). The parameters such as ciphertext size, encryption time, and throughput have been considered for performance evaluation, whereas statistical analysis like similarity measurement, correlation coefficient, histogram, and entropy analysis uses to check image pixels deviation. The number of pixels change rate (NPCR) and unified averaged changed intensity (UACI) were used to check the strength of the proposed encryption technique. The proposed model is robust with high resilience against eavesdropping, insider attack, and chosen-plaintext attack.
Central fever: a challenging clinical entity in neurocritical care
Keshav Goyal,Neha Garg,Parmod Bithal 대한신경집중치료학회 2020 대한신경집중치료학회지 Vol.13 No.1
Fever is probably the most frequent symptom observed in neurointensive care by healthcare providers. It is seen in almost 70% of neurocritically ill patients. Fever of central origin was first described in the journal Brain by Erickson in 1939. A significant number of patients develop this fever due to a noninfectious cause, but are often treated as having an infectious fever. Unjustified use of antibiotics adds to the increased cost of treatment and the emergence of resistant strains, contributing to additional morbidity. Since fever has a detrimental impact on the recovery of the acutely injured brain and contributes to an increased stay in the neurointensive care unit (NICU), timely and accurate diagnosis of the cause of fever in the NICU is imperative. Here, we try to understand the underlying mechanism, risk factors, clinical characteristics, diagnosis and management options of the central fever. We also make an attempt to differentiate two noninfectious causes of fever in the NICU: paroxysmal sympathetic hyperactivity and central fever.
Genetic Engineering of Streptomyces lividans TK24 for the production of kanamycin derivatives.
Keshav Kumar Nepal,Tae-Jin Oh,Hei Chan Lee,Jae Kyung Sohng 한국당과학회 2008 한국당과학회 학술대회 Vol.2008 No.1
Kanamycins, pseudotrisaccharides antibiotics, have three closely related structural form namely kanamycin A, kanamycin B and kanamycin C in which 2-DOS is substituted at the C-4 position by an aminoglucose functionality: 6-amino-6- deoxy-D-glucose, neosamine, and D -glucosamine respectively and at the C-6 position by 3-amino-3-deoxy-D-glucose (kanosamine). Here, we have Engineered Streptomyces lividans TK24 by expressing two sets of rebombinant plasmids pSK-7 and pSK-17 responsible for the production of paromamine and kanamycin C respectively. Bio-active secondary metabolite from pSK-17/SL against Bacillus subtilis and ESI/MS,LC/MS and ESI/MS/MS at 485 [M+H]+ were the evidences for the production of Kanamycin C.