The Durham Oriental Music Festivalandits Legacy

Keith Pratt,Simon Mills,Keith Howard 아시아음악학회 2017 Asian Musicology Vol.27 No.-

Between 1976 and 1982 the city and University of Durham, UK, hosted a series of three unprecedented festivals. Their aim was to introduce Western audiences to the traditional music of Asia by means of concerts, lectures, workshops, films and exhibitions. Countries represented by topclass artists and scholars were China, Korea, Japan, Turkey, Egypt, Iraq, Iran, India, Bangladesh, Thailand, Indonesia, Vietnam and Laos. Overcoming many difficulties, the Durham Oriental Music Festival acquired a worldwide reputation and successfully helped to promote Asian music and ethnomusicology in the West. In 2009 Durham University revived its aims by introducing a Festival of East Asian Music. More modest in scale, this annually promotes performance and study of musical themes from countries of East Asia, again putting emphasis on authenticity and high quality.

Han`guk-ŭi nongyo(Farming Songs of Korea)

Keith Howard(서평자) The Academy of Korean Studies 1990 Korea Journal Vol.30 No.4

Anthocyanin-Rich Grape Extract Blocks Breast Cell DNA Damage

Keith W. Singletary,Kwan-Jae Jung,Monica Giusti 한국식품영양과학회 2007 Journal of medicinal food Vol.10 No.2

Anthocyanins, belonging to the flavonoid family of phytochemicals, have received attention as agents that mayhave potential in preventing chronic diseases such as cardiovascular diseases and certain cancers. In the present study, an an-thocyanin-rich extract from Concord grapes [referred to as Concord grape extract (CGE)] and the anthocyanin delphinidinwere evaluated for their capacity to inhibit DNA adduct formation due to the environmental carcinogen benzo[a]pyrene (BP)in MCF-10F cells, a noncancerous, immortalized human breast epithelial cell line. CGE at 10 and 20 .g/mL and delphinidinat 0.6 .M concentrations significantly inhibited BPDNA adduct formation. This was associated with a significant increasein activities of the phase II detoxification enzymes glutathione S-transferase and NAD(P)H:quinone reductase 1. In addition,these grape components also suppressed reactive oxygen species (ROS) formation, but did not induce antioxidant responseelement-dependent transcription. Taken together, these data suggest that CGE and a component grape anthocyanin have breastcancer chemopreventive potential due in part to their capacity to block carcinogenDNA adduct formation, modulate activi-ties of carcinogen-metabolizing enzymes, and suppress ROS in these noncancerous human breast cells.

Lupus and Perioperative Complications in Elective Primary Total Hip or Knee Arthroplasty

Keith T Aziz,Matthew J Best,Richard L Skolasky,Karthik E Ponnusamy,Robert S Sterling,Harpal S Khanuja 대한정형외과학회 2020 Clinics in Orthopedic Surgery Vol.12 No.1

Background: The number of patients with systemic lupus erythematosus (herein, lupus) undergoing total hip arthroplasty (THA) or total knee arthroplasty (TKA) is increasing. There is disagreement about the effect of lupus on perioperative complication rates. We hypothesized that lupus would be associated with higher complication rates in patients who undergo elective primary THA or TKA. Methods: Records of more than 6.2 million patients from the National Inpatient Sample who underwent elective primary THA or TKA from 2000 to 2009 were reviewed. Patients with lupus (n = 38,644) were compared with those without lupus (n = 6,173,826). Major complications were death, pulmonary embolism, myocardial infarction, stroke, pneumonia, and acute renal failure. Minor complications were wound infection, seroma, deep vein thrombosis, hip dislocation, wound dehiscence, and hematoma. Patient age, sex, duration of hospital stay, and number of Elixhauser comorbidities were assessed for both groups. Multivariate logistic regression models using comorbidities, age, and sex as covariates were used to assess the association of lupus with major and minor perioperative complications. The alpha level was set to 0.001. Results: Among patients who underwent THA, those with lupus were younger (mean age, 56 vs. 65 years), were more likely to be women (87% vs. 56%), had longer hospital stays (mean, 4.0 vs. 3.8 days), and had more comorbidities (mean, 2.5 vs. 1.4) than those without lupus (all p < 0.001). In patients with THA, lupus was independently associated with major complications (odds ratio [OR], 1.4; 95% confidence interval [CI], 1.1 to 1.7) and minor complications (OR, 1.2; 95% CI, 1.0 to 1.5). Similarly, among patients who underwent TKA, those with lupus were younger (mean, 62 vs. 67 years), were more likely to be women (93% vs. 64%), had longer hospital stays (mean, 3.8 vs. 3.7 days), and had more comorbidities (mean, 2.8 vs. 1.7) than those without lupus (all p < 0.001). However, in TKA patients, lupus was not associated with greater odds of major complications (OR, 1.2; 95% CI, 0.9 to 1.4) or minor complications (OR, 1.1; 95% CI, 0.9 to 1.3). Conclusions: Lupus is an independent risk factor for major and minor perioperative complications in elective primary THA but not TKA.

Current Trends in Force/Torque Sensing

Keith A. Morris 제어로봇시스템학회 1989 제어로봇시스템학회 국내학술대회 논문집 Vol.1989 No.10

The Association of Delirium with Perioperative Complications in Primary Elective Total Hip Arthroplasty

Keith T Aziz,Matthew J Best,Zan Naseer,Richard L Skolasky,Karthik E Ponnusamy,Robert S Sterling,Harpal S Khanuja 대한정형외과학회 2018 Clinics in Orthopedic Surgery Vol.10 No.3

Background: Our goal was to determine whether postoperative delirium is associated with inpatient complication rates after primary elective total hip arthroplasty (THA). Methods: Using the National Inpatient Sample, we analyzed records of patients who underwent primary elective THA from 2000 through 2009 to identify patients with delirium (n = 13,551) and without delirium (n = 1,992,971) and to assess major perioperative complications (acute renal failure, death, myocardial infarction, pneumonia, pulmonary embolism, and stroke) and minor perioperative complications (deep vein thrombosis, dislocation, general procedural complication, hematoma, seroma, and wound infection). Patient age, sex, length of hospital stay, and number of comorbidities were assessed. We used multivariate logistic regression to determine the association of delirium with complication rates (significance, p < 0.01). Results: Patients with delirium were older (mean, 75 ± 0.2 vs. 65 ± 0.1 years), were more likely to be male (56% vs. 52%), had longer hospital stays (mean, 5.7 ± 0.07 vs. 3.8 ± 0.02 days), and had more comorbidities (mean, 2.8 ± 0.03 vs. 1.4 ± 0.01) (all p < 0.001) versus patients without delirium. Patients with delirium were more likely to have major (11% vs. 3%) and minor (17% vs. 7%) perioperative complications versus patients without delirium (both p < 0.001). When controlling for age, sex, and number of comorbidities, delirium was independently associated with major and minor complications (odds ratio, 2.0; 95% confidence interval, 1.7 to 2.3). Conclusions: Delirium is an independent risk factor for major and minor perioperative complications after primary elective THA.

More Than Tourism

Keith Dinnie 동아시아재단 2012 Global Asia Vol.7 No.3

On the Backfoot : How the UK’s fight against COVID-19 began

Keith Cooper,Arthy Hartwell 대한의사협회 의료정책연구소 2020 의료정책포럼 Vol.18 No.4

Diabetes Care of Non-obese Korean Americans: Considerable Room for Improvement

Keith Tsz-Kit Chan,Karen M. Kobayashi,Adity Roy,Esme Fuller-Thomson 대한가정의학회 2019 Korean Journal of Family Medicine Vol.40 No.2

Background: Family doctors are increasingly managing the diabetes care of Korean-Americans. Little is known about the prevalence of diabetes among non-obese Korean-Americans, or the extent to which they receive timely and appropriate diabetes care. The purpose of this investigation is to: (1) identify the prevalence of diabetes and to determine the adjusted odds of diabetes among non-obese Korean-Americans compared to non-Hispanic White (NHW) Americans, (2) examine the factors associated with having diabetes in a large sample of non-obese Korean- Americans, and (3) determine the prevalence and adjusted odds of optimal frequency of eye care, foot care and A1C blood glucose level monitoring among non-obese Korean-Americans with diabetes in comparison to NHWs with diabetes. Methods: Secondary analysis of population-based data from the combined 2007, 2009, and 2011 adult California Health Interview Survey. The sample included 74,361 respondents with body mass index (BMI) <30 kg/m2 (referred to as ‘non-obese BMI’), of whom 2,289 were Korean-Americans and 72,072 were NHWs, and 4,576 had diabetes. Results: The prevalence and adjusted odds of diabetes among non-obese Korean-Americans are significantly higher than among their NHW peers. More than 90% of Korean-Americans with diabetes were non-obese. NHWs had substantially higher odds of having optimal frequency of eye care, foot care and A1C glucose level monitoring, even after adjusting for insulin dependence, sex, age, education, income, and BMI. Conclusion: Non-obese Korean-Americans are at higher risk for diabetes and are much less likely to receive optimal diabetes care in comparison to NHWs. Targeted outreach is necessary.

The Bioactive Agent Ergothioneine, a Key Component of Dietary Mushrooms, Inhibits Monocyte Binding to Endothelial Cells Characteristic of Early Cardiovascular Disease

Keith R. Martin 한국식품영양과학회 2010 Journal of medicinal food Vol.13 No.6

Regular consumption of fruits and vegetables is strongly associated with a reduced risk of cardiovascular disease (CVD). This effect occurs, in part, because of the plethora of bioactive agents in foods and their subsequent function as antioxidants. Ergothioneine (ERT), a novel antioxidant, is present in edible mushrooms and is not synthesized, but is accumulated, by humans through diet. In this study, we tested whether ERT, a bioactive agent, could interrupt pro-inflammatory induction of adhesion molecule expression associated with atherogenesis. Human aortic endothelial cells (HAECs) were incubated with increasing concentrations of ERT (0.01–10.0mM) overnight (16 hours) followed by incubation with medium alone or with the pro-inflammatory cytokine interleukin (IL)-1β (5ng/mL) for 6 hours to induce expression of vascular cell adhesion molecule-1 (VCAM-1), intercellular adhesion molecule-1 (ICAM-1), and endothelial-leukocyte adhesion molecule (ELAM-1 or E-selectin). ERT at 0.1–0.3mM significantly (P<.05) reduced VCAM-1, ICAM-1, and E-selectin expression up to 41%. VCAM-1 was suppressed to the greatest extent followed by E-selectin and then ICAM-1. We next tested if binding of preloaded U937 human monocytes to HAECs would be inhibited. U937 binding to HAECs was significantly reduced in IL-1β-stimulated HAECs preincubated with 1 and 3mM ERT. Unstimulated monolayers demonstrated marginal, but significant, reductions. ERT was not toxic to HAECs at any concentration used. These data provide evidence that ERT found in commonly consumed dietary mushrooms can protect against events observed in atherogenesis, suggesting increased dietary intake of edible mushrooms would be a prudent medicinal means of reducing CVD risk.