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국제동향 - Sustainable Growth of Asian Economies and Importance of Infrastructure Development
Motohashi, Kazuyuki Korea Pallet and Container Association 2013 파렛트 뉴스 Vol.70 No.-
본 원고는 지난 2013년 7월 17일 일본 동경 'Mielparque Tokyo'에서 열린 2013 제8회 APSF(Asia Pallet System Federation) 총회 기조강연으로 일본 동경대학교의 Kazuyuki Motohashi 교수가 발표하였습니다.
Role of Sphingolipids and Metabolizing Enzymes in Hematological Malignancies
Kazuyuki Kitatani,Toshiro Okazaki,Makoto Taniguchi 한국분자세포생물학회 2015 Molecules and cells Vol.38 No.6
Sphingolipids such as ceramide, sphingosine-1-phosphate and sphingomyelin have been emerging as bioactive lipids since ceramide was reported to play a role in human leukemia HL-60 cell differentiation and death. Recently, it is well-known that ceramide acts as an inducer of cell death, that sphingomyelin works as a regulator for microdomain function of the cell membrane, and that sphingosine-1- phosphate plays a role in cell survival/proliferation. The lipids are metabolized by the specific enzymes, and each metabolite could be again returned to the original form by the reverse action of the different enzyme or after a long journey of many metabolizing/synthesizing pathways. In addition, the metabolites may serve as reciprocal biomodulators like the rheostat between ceramide and sphingosine-1-phosphate. Therefore, the change of lipid amount in the cells, the subcellular localization and the downstream signal in a specific subcellular organelle should be clarified to understand the pathobiological significance of sphingolipids when extracellular stimulation induces a diverse of cell functions such as cell death, proliferation and migration. In this review, we focus on how sphingolipids and their metabolizing enzymes cooperatively exert their function in proliferation, migration, autophagy and death of hematopoetic cells, and discuss the way developing a novel therapeutic device through the regulation of sphingolipids for effectively inhibiting cell proliferation and inducing cell death in hematological malignancies such as leukemia, malignant lymphoma and multiple myeloma.
( Kazuyuki Nagai ) 한국금융법학회 2011 金融法硏究 Vol.8 No.1
In Japan, the rules of insurance was established in the Commercial Code since 1899. After then, Japan has become one of the most industrialized countries in the world, and its population has been progressively growing older. So, this old rules of insurance was facing some new challenges in these years, for example, how to protect an insurant. In the past several years, Japan had been particularly involved with efforts at improving its insurance law. And Japan had to find some solutions for these new challenges, and to make some innovation. In 2008, the Insurance Act in Japan was enacted with to be more contemporary writings. The main purpose in this new insurance law is to be written in an easy style for the people who repeatedly ask their insurance law to be necessary and reasonable. And then, Japan launched its new insurance law in recognizing that it is a key in a modern safe society to protect an insurant. In this paper, I would like to focus two-important topics in this new insurance law, as follows, ① what is the intention of the new insurance law, ② how the new insurance law is to protect an insurant. These innovations in the new insurance law should and will be an example that other countries follow in the future.
Analysis of Relaying Probability in Wireless Multi-hop Networks with QoS Routing
Kazuyuki Miyakita,Keisuke Nakano,Tetsuya Hasegawa,Masakazu Sengoku,Shoji Shinoda 대한전자공학회 2009 ITC-CSCC :International Technical Conference on Ci Vol.2009 No.7
In wireless multi-hop networks, source and destination nodes usually have some candidate paths between them, and communication quality depends on selection of a multi-hop path from these candidates. We theoretically analyzed ETX which is a measure of communication quality, for three routing algorithms in one-dimensional multi-hop networks. In this paper, we theoretically analyze relaying probability of each relay node in a one-dimensional multi-hop network with QoS routing, which minimizes ETX and propose an algorithm that makes relaying probability of each node as uniform as possible.
Prediction of Individual Thermal Sensation Using Unspecified Sensors in Sensor Networks
Kazuyuki Kojima 제어로봇시스템학회 2008 제어로봇시스템학회 국제학술대회 논문집 Vol.2008 No.10
This paper describes a prediction method for predicting human thermal sensation by using unspecified sensors over an unstable sensor network. First, a dynamically changing neural network is utilized for predicting the thermal sensation. The neural network is formed dynamically and trained by considering the strength of the correlation between the sensor readings and the thermal sensations of subjects. The neural network is modified when the difference between its estimation and the actual values increases. Next, in order to perform experiments with actual subjects, we built a sensor network in an indoor environment. For two weeks, we regularly measured certain values, such as the temperature in the environment, and investigated the thermal sensation of the subjects once every fifteen minutes while they were in this environment. Then, using our method, the thermal sensation and the thermal values were associated with each other, after which a dynamical neural network which estimates each thermal sensation was built automatically.