Retinal Nerve Fiber Layer Thickness and Its Relationship With Executive Functions in Adult Attention Deficit Hyperactivity Disorder Patients

Derya Kaymak,I˙brahim Gü,ndog˘mus¸,Mihriban Dalkıran,Murat Kü,ç,ü,kevciliog˘ lu,Ö,zcan Uzun 대한신경정신의학회 2021 PSYCHIATRY INVESTIGATION Vol.18 No.12

Objective The aim of this study was to compare the thickness of the retinal nerve fiber layer (RNFL) with controls in individuals with attention deficit hyperactivity disorder (ADHD) and to examine the relationship between RNFL thickness and the level of performance in disease severity and executive function tests in ADHD cases.Methods The study included 38 volunteer patients diagnosed with ADHD and 30 healthy volunteers. Adult ADHD self-report scale was used for ADHD symptom severity. Executive functions were evaluated by Digit Span Test, Verbal Fluency Test, Stroop Test, and Trail Making Test. RNFL thickness of all participants was evaluated using optical coherence tomography (OCT).Results In the comparison of RNFL values, it was found that right mean, right temporal, right temporal inferior, left mean, left nasal, and left nasal inferior quadrant values were statistically thinner in ADHD cases compared to the control group (p<0.05). There was no statistically significant correlation between the mean RNFL thickness values of the right and left eyes of ADHD cases and the symptom severity and performance levels in executive function tests.Conclusion This study is a guide in terms of being the first study investigating the relationship between RNFL thickness, symptom severity, and various neuropsychological tests in adults with ADHD.

Core-Type Transformer Design Method with Integrated Series Inductance for DC-DC Converters

Murat Kaymak,Mustafa Enes Fincan,Rik W. De Doncker 전력전자학회 2019 ICPE(ISPE)논문집 Vol.2019 No.5

This paper presents two different methods to design Medium-Frequency Transformers (MFT) with required ac-link series inductance of a galvanically isolated dc-dc converter. The series inductance of the ac-link is usually formed by the leakage or stray inductance of the MFT and an additional external inductor. Here, two approaches are presented, avoiding the extra external series inductor by designing the transformer with an increased and defined leakage inductance.

The First Design and Application of Floating Photovoltaic (FPV) Energy Generation Systems in Turkey with Structural and Electrical Performance

Mustafa Kemal Kaymak,Ahmet Duran Sahin 한국정밀공학회 2022 International Journal of Precision Engineering and Vol.9 No.3

Greenhouse gas (GHG) emissions are primarily due to the exploitation of fossil fuel as an energy source, and one of the energy alternatives for the reduction of emissions is the use of renewable energy sources; one of these is solar irradiation conversion to useable clean energy. In the city of Istanbul, floating photovoltaic (FPV) installation started in 2017, on one of the lakes with an extensive surface area, Buyukcekmece, which supplies water to the city. To reduce evaporation losses and to generate electricity, two FPV prototypes were installed, with capacities of 9 and 90 kWp. Due to the location and climate of Buyukcekmece Lake, all system components including steel construction, metal sheet, maintenance way, connecting parts, and pontoons must resist extreme weather conditions, especially harsh waves and high wind loads. This paper is focused on a survey of the survival performance of the FPV system under real weather conditions without blockage of evaporation, just the reduction of it. Stress and strain tests were also applied to pontoons, one of the vital components for floating systems. The elasticity module, yield limit and tensile strength were evaluated as 0.42 GPA, 11.5 mPA, and 19 mPA, respectively. The wave height was calculated by means of four practical relationships, taking the lake’s distinctive characteristics into consideration. The electricity generation of 90 kWp FPV measured for June 2017 was 5189 kWh. The structural and electrical performance results from these systems in the city of Istanbul could be applied further to large scale FPV applications in water reservoirs nationally and internationally.

Relationships between cusp points in the extended modular group and Fibonacci numbers

¨Ozden Koruo˘glu,Sule Kaymak Sarica,Bilal Demir,A. Furkan Kaymak 호남수학회 2019 호남수학학술지 Vol.41 No.3

Cusp (parabolic) points in the extended modular group $\overline{\Gamma}$ are basically the images of infinity under the group elements. This implies that the cusp points of $\overline{\Gamma}$ are just rational numbers and the set of cusp points is $Q_{\infty}=Q\cup\left\{ \infty\right\} .$The Farey graph $F$ is the graph whose set of vertices is $Q_{\infty}$ and whose edges join each pair of Farey neighbours. Each rational number $x$ has an integer continued fraction expansion (ICF) $x=[b_{1},...,b_{n}].$ We get a path from $\infty$ to $x$ in $F$ as \TEXTsymbol{<}$\infty,C_{1},...,C_{n}>$ for each ICF. In this study, we investigate relationships between Fibonacci numbers, Farey graph, extended modular group and ICF. Also, we give a computer program that computes the geodesics, block forms and matrix represantations.

RELATIONSHIPS BETWEEN CUSP POINTS IN THE EXTENDED MODULAR GROUP AND FIBONACCI NUMBERS

Koruoglu, Ozden,Sarica, Sule Kaymak,Demir, Bilal,Kaymak, A. Furkan The Honam Mathematical Society 2019 호남수학학술지 Vol.41 No.3

Cusp (parabolic) points in the extended modular group ${\bar{\Gamma}}$ are basically the images of infinity under the group elements. This implies that the cusp points of ${\bar{\Gamma}}$ are just rational numbers and the set of cusp points is $Q_{\infty}=Q{\cup}\{{\infty}\}$.The Farey graph F is the graph whose set of vertices is $Q_{\infty}$ and whose edges join each pair of Farey neighbours. Each rational number x has an integer continued fraction expansion (ICF) $x=[b_1,{\cdots},b_n]$. We get a path from ${\infty}$ to x in F as $<{\infty},C_1,{\cdots},C_n>$ for each ICF. In this study, we investigate relationships between Fibonacci numbers, Farey graph, extended modular group and ICF. Also, we give a computer program that computes the geodesics, block forms and matrix represantations.

The evaluation of maximum bite force in the occlusal rehabilitation of patient with Angle Class III malocclusion: a case report

Karakis, Duygu,Kaymak, Dilek,Dogan, Arife The Korean Academy of Prosthodonitics 2013 The Journal of Advanced Prosthodontics Vol.5 No.3

The case report describes the occlusal rehabilitation of a male patient with Angle Class III malocclusion and its effect on maximum bite force. The main complaints of patient were masticatory difficulty and poor esthetic. The patient's expectations from the treatment were a good esthetic and function with a less invasive and relatively promptly way. Therefore, increasing of the occlusal vertical dimension (OVD) and then restoring the maxillary and mandibular teeth was chosen by the patient among the treatment options. At the beginning of treatment maximum bite force of patient was measured. Then an occlusal splint was provided to evaluate the adaptation of the patient to the altered OVD. Full mouth rehabilitation with metal ceramic restorations was made. After the completion of full mouth restoration, bite force measurement was repeated and patient exhibited increased maximum bite force. Full mouth restorative treatment in a patient with Class III malocclusion could be an effective treatment approach to resolve esthetic concern and to improve masticatory function related to maximum bite force.

The evaluation of maximum bite force in the occlusal rehabilitation of patient with Angle Class III malocclusion: a case report

Arife Dogan,Dilek Kaymak,Duygu Karakıs 대한치과보철학회 2013 The Journal of Advanced Prosthodontics Vol.5 No.3

The case report describes the occlusal rehabilitation of a male patient with Angle Class III malocclusion and its effect on maximum bite force. The main complaints of patient were masticatory difficulty and poor esthetic. The patient's expectations from the treatment were a good esthetic and function with a less invasive and relatively promptly way. Therefore, increasing of the occlusal vertical dimension (OVD) and then restoring the maxillary and mandibular teeth was chosen by the patient among the treatment options. At the beginning of treatment maximum bite force of patient was measured. Then an occlusal splint was provided to evaluate the adaptation of the patient to the altered OVD. Full mouth rehabilitation with metal ceramic restorations was made. After the completion of full mouth restoration, bite force measurement was repeated and patient exhibited increased maximum bite force. Full mouth restorative treatment in a patient with Class III malocclusion could be an effective treatment approach to resolve esthetic concern and to improve masticatory function related to maximum bite force.

Treatment Outcomes and Survival Study of Gastric Cancer Patients: A Retrospective Analysis in an Endemic Region

Basaran, Hamit,Koca, Timur,Cerkesli, Arda Kaymak,Arslan, Deniz,Karaca, Sibel Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.5

Purpose: To present information about prognostic factors of gastric cancer patients treated in our Erzurum center including age, gender, tumour location, pathological grade, stage and the effect of treatment on survival. Materials and Methods: This retrospective study was performed on patients who applied to our clinic and diagnosed as gastric cancer. Age and gender of the patients, primary location, histopathological characteristics, TNM stage of the gastric cancers (GCs), treatment applied, oncological treatment modalities and survival outcomes were studied. A univariate analysis of potential prognostic factors was performed with the log-rank test for categorical factors and parameters with a p value < 0.05 at the univariate step were included in the multivariate regression. Results: A total of 228 patients with a confirmed diagnosis of gastric cancer were included in the study with a male/female ratio of 1.47. Median follow-up period was estimated as 22.3 (range, 3 to 96) months. When diagnosis of the patients at admission was analysed, stage III patients were most frequently encountered (n=147; 64.5%). One hundred and twenty-six (55.3%) underwent surgical treatment, while 117 (51.3%) were given adjuvant chemotherapy. Median overall survival time was 18.0 (${\pm}1.19$) months. Mean overall survival rates for 1, 2, 3 and 5 years were $68{\pm}0.031%$, $36{\pm}0.033%$, $24{\pm}0.031%$and $15.5{\pm}0.036%$, respectively. Univariate variables found to be significant for median OS in the multivariate analysis were evaluated with Cox regression analysis. A significant difference was found among TNM stage groups, location of the tumour and postoperative adjuvant treatment receivers (p values were 0.011, 0.025 and 0.001, respectively). Conclusions: This study revealed that it is possible to achieve long-term survival of gastric cancer with early diagnosis. Besides, in locally advanced GC patients, curative resection followed by adjuvant concomitant chemoradiotherapy based on the McDonald regimen was an independent prognostic factor for survival.

Thiol-disulphide Homeostasis in Patients with Schizophrenia: The Potential Biomarkers of Oxidative Stress in Acute Exacerbation of Schizophrenia

Şükrü Alperen Korkmaz,Semra Ulusoy Kaymak,Salim Neşelioğlu,Özcan Erel 대한정신약물학회 2024 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.22 No.1

Objective: Recent evidence suggests that oxidative stress contributes to the pathophysiology of schizophrenia. This study aimed to compare thiol-disulphide homeostasis in acute and stable phases of schizophrenia for the first time. Methods: Among the patients with schizophrenia, 61 in the acute-phase and 61 in the stable phase of their illness were enrolled in the study. Native thiol (NT), total thiol (TT), disulphide (SS), disulphide/native thiol, disulphide/total thiol, and native thiol/total thiol for thiol-disulphide homeostasis were compared between the groups. The Brief Psychiatric Rating Scale (BPRS), Scale for the Assessment of Positive/Negative Symptoms (SAPS/SANS), Clinical Global Impression- Severity Scale (CGI-S), Barnes Akathisia Rating Scale, and Simpson-Angus Scale were used to assess symptoms. Results: After controlling for age, sex, body mass index, and smoking status there were significant differences in NT, TT, SS/NT, SS/TT, and NT/TT, but not SS. Thiol/disulphide homeostasis has shifted in favour of the oxidative side in patients with acute-phase compared to that in stable schizophrenia. BPRS, SAPS, and CGI-S scores were significantly correlated with all six thiol-disulphide parameters, but not SANS, when controlling for age and sex. Significant receiver operating characteristic (ROC) curves were obtained for all thiol-disulphide homeostasis parameters. Discriminant analysis was found to be statistically significant in discriminating between groups. Conclusion: These results show that oxidative status increases thiol-disulphide homeostasis in patients with acute-phase schizophrenia compared to those with stable schizophrenia. These findings suggest that thiol-disulphide parameters can be used as biomarkers for the acute exacerbation of schizophrenia.

Awareness of Turkish Female Adolescents and Young Women about HPV and their Attitudes Towards HPV Vaccination

Ozyer, Sebnem,Uzunlar, Ozlem,Ozler, Sibel,Kaymak, Oktay,Baser, Eralp,Gungor, Tayfun,Mollamahmutoglu, Leyla Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.8

Background: The aim of the study was to assess the knowledge about HPV and HPV vaccines and attitudes towards vaccination among the females aged 9-24 years in Turkey. Materials and Methods: Self-administered questionnaires were filled out individually by the participants covering demographic information, knowledge about HPV infection and HPV vaccines, attitudes towards vaccination, and the perceptions of them about their parental attitudes about vaccination. Results: Of the 408 subjects participating in the study, 41.6% (n=170) had heard of HPV. Thirty-three percent (n=136) knew the causal relationship between HPV and cervical cancer. Only 27.9% (n=114) of them knew that HPV vaccines can prevent cervical cancer. Eleven percent (n=46) of the females participating in the study were willing to be vaccinated, and only 1.4% (n=6) were already vaccinated at the current time. The main reason listed among the participants who were not willing to be vaccinated was lack of information. Conclusions: Awareness and knowledge of Turkish female adolescents and young women about HPV, relation with cervical cancer and prevention of cervical cancer by Pap smear and vaccine are still limited. If the most important barrier to vaccination, which is reported as lack of information, were to be addressed, it would greatly impact the decision-making and vaccine acceptance.